1
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Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human.
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Proc Natl Acad Sci U S A
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2005
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2
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Systematic analysis of head-to-head gene organization: evolutionary conservation and potential biological relevance.
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PLoS Comput Biol
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2006
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2.11
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3
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Construction of a chloroplast protein interaction network and functional mining of photosynthetic proteins in Arabidopsis thaliana.
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Cell Res
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2008
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1.58
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4
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Comparison of normalization methods with microRNA microarray.
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Genomics
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2008
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1.51
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5
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Analysis and prediction of the metabolic stability of proteins based on their sequential features, subcellular locations and interaction networks.
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PLoS One
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2010
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1.51
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6
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Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data.
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BMC Bioinformatics
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2007
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1.35
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7
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Hierarchical modularity of nested bow-ties in metabolic networks.
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BMC Bioinformatics
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2006
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1.33
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8
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Semantic search among heterogeneous biological databases based on gene ontology.
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Acta Biochim Biophys Sin (Shanghai)
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2004
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1.30
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9
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Prediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profiles.
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PLoS One
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2009
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1.26
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10
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Modular co-evolution of metabolic networks.
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BMC Bioinformatics
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2007
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1.23
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11
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DCGL: an R package for identifying differentially coexpressed genes and links from gene expression microarray data.
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Bioinformatics
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2010
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1.23
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12
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Link-based quantitative methods to identify differentially coexpressed genes and gene pairs.
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BMC Bioinformatics
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2011
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1.19
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13
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Combinatorial network of primary and secondary microRNA-driven regulatory mechanisms.
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Nucleic Acids Res
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2009
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1.19
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14
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A HMM-based method to predict the transmembrane regions of beta-barrel membrane proteins.
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Comput Biol Chem
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2003
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1.18
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15
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In silico discovery of human natural antisense transcripts.
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BMC Bioinformatics
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2006
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1.16
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16
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miR-612 suppresses the invasive-metastatic cascade in hepatocellular carcinoma.
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J Exp Med
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2013
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1.10
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17
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Identification and target prediction of miRNAs specifically expressed in rat neural tissue.
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BMC Genomics
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2009
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1.10
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18
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The prediction of interferon treatment effects based on time series microarray gene expression profiles.
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J Transl Med
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2008
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1.10
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19
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Dynamic analysis of optimality in myocardial energy metabolism under normal and ischemic conditions.
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Mol Syst Biol
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2006
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1.10
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20
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Proteomics characterization of the cytotoxicity mechanism of ganoderic acid D and computer-automated estimation of the possible drug target network.
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Mol Cell Proteomics
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2007
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1.05
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21
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DCGL v2.0: an R package for unveiling differential regulation from differential co-expression.
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PLoS One
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2013
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1.02
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22
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Sys-BodyFluid: a systematical database for human body fluid proteome research.
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Nucleic Acids Res
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2008
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1.02
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23
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High-coverage proteome analysis reveals the first insight of protein modification systems in the pathogenic spirochete Leptospira interrogans.
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Cell Res
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2009
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1.01
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24
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Computational methods for protein-protein interaction and their application.
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Curr Protein Pept Sci
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2005
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0.99
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25
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KDE Bioscience: platform for bioinformatics analysis workflows.
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J Biomed Inform
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Large scale phosphoproteome profiles comprehensive features of mouse embryonic stem cells.
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Mol Cell Proteomics
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27
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A negative cooperativity mechanism of human CYP2E1 inferred from molecular dynamics simulations and free energy calculations.
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J Chem Inf Model
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2011
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28
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Localized-statistical quantification of human serum proteome associated with type 2 diabetes.
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PLoS One
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2008
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0.93
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29
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Molecular dynamics studies on the interactions of PTP1B with inhibitors: from the first phosphate-binding site to the second one.
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Protein Eng Des Sel
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2009
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0.91
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30
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Identifying modules of coexpressed transcript units and their organization of Saccharopolyspora erythraea from time series gene expression profiles.
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PLoS One
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2010
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31
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An improved kinetic model for the acetone-butanol-ethanol pathway of Clostridium acetobutylicum and model-based perturbation analysis.
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BMC Syst Biol
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2011
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0.90
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32
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Prediction of beta-turns with learning machines.
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Peptides
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2003
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33
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Small envelope protein E of SARS: cloning, expression, purification, CD determination, and bioinformatics analysis.
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Acta Pharmacol Sin
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2003
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34
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Systems perspectives on erythromycin biosynthesis by comparative genomic and transcriptomic analyses of S. erythraea E3 and NRRL23338 strains.
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BMC Genomics
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2013
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35
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Combining gene expression profiles and protein-protein interaction data to infer gene functions.
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J Biotechnol
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36
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3D structure modeling of cytochrome P450 2C19 and its implication for personalized drug design.
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Biochem Biophys Res Commun
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2007
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0.89
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37
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Adipogenesis licensing and execution are disparately linked to cell proliferation.
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Cell Res
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2009
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Protein sumoylation sites prediction based on two-stage feature selection.
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Mol Divers
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Rig-I regulates NF-κB activity through binding to Nf-κb1 3'-UTR mRNA.
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Proc Natl Acad Sci U S A
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Identification of probable genomic packaging signal sequence from SARS-CoV genome by bioinformatics analysis.
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Acta Pharmacol Sin
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2003
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Combinatorial network of transcriptional regulation and microRNA regulation in human cancer.
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BMC Syst Biol
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Discovering multiple transcripts of human hepatocytes using massively parallel signature sequencing (MPSS).
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BMC Genomics
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Induced fit for mRNA/TIS11d complex.
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J Chem Phys
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Identification of p27/KIP1 expression level as a candidate biomarker of response to rapalogs therapy in human cancer.
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J Mol Med (Berl)
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DBH2H: vertebrate head-to-head gene pairs annotated at genomic and post-genomic levels.
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Reversal of coenzyme specificity and improvement of catalytic efficiency of Pichia stipitis xylose reductase by rational site-directed mutagenesis.
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Biotechnol Lett
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A high-throughput approach for subcellular proteome: identification of rat liver proteins using subcellular fractionation coupled with two-dimensional liquid chromatography tandem mass spectrometry and bioinformatic analysis.
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Mol Cell Proteomics
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Large number of phosphotransferase genes in the Clostridium beijerinckii NCIMB 8052 genome and the study on their evolution.
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BMC Bioinformatics
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A 3D model of SARS_CoV 3CL proteinase and its inhibitors design by virtual screening.
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Acta Pharmacol Sin
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Exploring mitochondrial evolution and metabolism organization principles by comparative analysis of metabolic networks.
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Genomics
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Analysis of gene expression profile in gastric cancer cells stimulated with Helicobacter pylori isogenic strains.
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J Med Microbiol
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52
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Scoring hidden Markov models to discriminate beta-barrel membrane proteins.
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Comput Biol Chem
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The discovery of novel protein-coding features in mouse genome based on mass spectrometry data.
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Genomics
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Crosstissue coexpression network of aging.
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GalNAc-transferase specificity prediction based on feature selection method.
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cGRNB: a web server for building combinatorial gene regulatory networks through integrated engineering of seed-matching sequence information and gene expression datasets.
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Negatively cooperative binding properties of human cytochrome P450 2E1 with monocyclic substrates.
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Curr Drug Metab
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Concurrent quantification of proteome and phosphoproteome to reveal system-wide association of protein phosphorylation and gene expression.
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Mol Cell Proteomics
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Prediction of protein secondary structure using improved two-level neural network architecture.
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Predicting protein oxidation sites with feature selection and analysis approach.
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Selection of reprogramming factors of induced pluripotent stem cells based on the protein interaction network and functional profiles.
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Protein Pept Lett
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Exploration of conformational transition in the aryl-binding site of human FXa using molecular dynamics simulations.
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Comparisons of graph-structure clustering methods for gene expression data.
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Prediction of prokaryotic promoters based on prediction of transcriptional units.
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Molecular dynamics studies on the conformational transitions of adenylate kinase: a computational evidence for the conformational selection mechanism.
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A comparison of computational methods for identifying virulence factors.
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Cancer classification from the gene expression profiles by Discriminant Kernel-PLS.
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Putative hAPN receptor binding sites in SARS_CoV spike protein.
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[Analysis and application of SNP and haplotype in the human genome].
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Analyses of copy number variation of GK rat reveal new putative type 2 diabetes susceptibility loci.
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Global transcriptome analysis profiles metabolic pathways in traditional herb Astragalus membranaceus Bge. var. mongolicus (Bge.) Hsiao.
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Computational studies on the substrate interactions of influenza A virus PB2 subunit.
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Structural flexibility and interactions of PTP1B's S-loop.
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Autoinhibitory mechanism for the mutation-induced impaired FGF9 signaling.
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Structural basis for the mutation-induced dysfunction of human CYP2J2: a computational study.
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Sorting out inherent features of head-to-head gene pairs by evolutionary conservation.
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Comparison of a proteomic approach with a microarray-based approach to detect exons in the mouse genome.
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Nat Genet
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Support vector machine for predicting alpha-turn types.
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MPSS: an integrated database system for surveying a set of proteins.
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Splice blocking of zygotic sox31 leads to developmental arrest shortly after Mid-Blastula Transition and induces apoptosis in zebrafish.
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FEBS Lett
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Modeling the effects of cell cycle M-phase transcriptional inhibition on circadian oscillation.
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PLoS Comput Biol
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EcoBrowser: a web-based tool for visualizing transcriptome data of Escherichia coli.
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Partition dataset according to amino acid type improves the prediction of deleterious non-synonymous SNPs.
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Biochem Biophys Res Commun
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EMMA: an efficient massive mapping algorithm using improved approximate mapping filtering.
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Association between alcohol, smoking and HLA-DQA1*0201 genotype in psoriasis.
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