Published in Trends Cell Biol on June 11, 2010
TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone. Am J Hum Genet (2011) 1.65
Cilia in the CNS: the quiet organelle claims center stage. Neuron (2011) 1.59
The roles of evolutionarily conserved functional modules in cilia-related trafficking. Nat Cell Biol (2013) 1.42
How do cilia organize signalling cascades? Philos Trans R Soc Lond B Biol Sci (2014) 1.19
Induction of Ran GTP drives ciliogenesis. Mol Biol Cell (2011) 1.13
The type 3 adenylyl cyclase is required for novel object learning and extinction of contextual memory: role of cAMP signaling in primary cilia. J Neurosci (2011) 1.05
A rhodopsin-guanylyl cyclase gene fusion functions in visual perception in a fungus. Curr Biol (2014) 0.98
Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites. PLoS Biol (2014) 0.95
Gastric pouches and the mucociliary sole: setting the stage for nervous system evolution. Philos Trans R Soc Lond B Biol Sci (2015) 0.95
Transcriptional profiling of C. elegans DAF-19 uncovers a ciliary base-associated protein and a CDK/CCRK/LF2p-related kinase required for intraflagellar transport. Dev Biol (2011) 0.94
Speed, sensitivity, and stability of the light response in rod and cone photoreceptors: facts and models. Prog Retin Eye Res (2012) 0.94
Changes in cGMP levels affect the localization of EGL-4 in AWC in Caenorhabditis elegans. PLoS One (2012) 0.90
Ciliopathy proteins establish a bipartite signaling compartment in a C. elegans thermosensory neuron. J Cell Sci (2014) 0.89
The apical complex provides a regulated gateway for secretion of invasion factors in Toxoplasma. PLoS Pathog (2014) 0.85
Controlling fertilization and cAMP signaling in sperm by optogenetics. Elife (2015) 0.83
Electrical Signaling in Motile and Primary Cilia. Bioscience (2014) 0.82
MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone. PLoS Biol (2016) 0.81
Localization of a guanylyl cyclase to chemosensory cilia requires the novel ciliary MYND domain protein DAF-25. PLoS Genet (2010) 0.81
A novel biosensor to study cAMP dynamics in cilia and flagella. Elife (2016) 0.80
The eukaryotic flagellum makes the day: novel and unforeseen roles uncovered after post-genomics and proteomics data. Curr Protein Pept Sci (2012) 0.78
From damage response to action potentials: early evolution of neural and contractile modules in stem eukaryotes. Philos Trans R Soc Lond B Biol Sci (2016) 0.78
A Cyclic GMP-Dependent K+ Channel in the Blastocladiomycete Fungus Blastocladiella emersonii. Eukaryot Cell (2015) 0.76
"With a Little Help from My Friends"-Social Motility in Trypanosoma brucei. PLoS Pathog (2015) 0.76
Receptor Guanylyl Cyclases in Sensory Processing. Front Endocrinol (Lausanne) (2017) 0.75
Early eukaryotic origins for cilia-associated bioactive peptide-amidating activity. J Cell Sci (2016) 0.75
PACRG, a protein linked to ciliary motility, mediates cellular signaling. Mol Biol Cell (2016) 0.75
cAMP signalling in trypanosomatids: role in pathogenesis and as a drug target. Trends Parasitol (2015) 0.75
cGMP Signalling Mediates Water Sensation (Hydrosensation) and Hydrotaxis in Caenorhabditis elegans. Sci Rep (2016) 0.75
Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene. Cell (2004) 6.10
Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome. Nature (2003) 5.96
The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4. Nat Genet (2006) 5.36
Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat Genet (2005) 4.76
The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression. Nat Genet (2004) 3.86
Functional coordination of intraflagellar transport motors. Nature (2005) 3.43
Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport. Genes Dev (2004) 3.21
Functional genomics of the cilium, a sensory organelle. Curr Biol (2005) 3.11
MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis. J Cell Biol (2011) 3.11
Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome. Nat Genet (2004) 2.64
Piecing together a ciliome. Trends Genet (2006) 2.57
Analysis of xbx genes in C. elegans. Development (2005) 2.39
Mechanism of transport of IFT particles in C. elegans cilia by the concerted action of kinesin-II and OSM-3 motors. J Cell Biol (2006) 2.32
The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization. EMBO Rep (2012) 2.17
Heterozygous mutations in BBS1, BBS2 and BBS6 have a potential epistatic effect on Bardet-Biedl patients with two mutations at a second BBS locus. Hum Mol Genet (2003) 1.87
Sensory ciliogenesis in Caenorhabditis elegans: assignment of IFT components into distinct modules based on transport and phenotypic profiles. Mol Biol Cell (2007) 1.82
Intraflagellar transport and the generation of dynamic, structurally and functionally diverse cilia. Trends Cell Biol (2009) 1.76
MKKS/BBS6, a divergent chaperonin-like protein linked to the obesity disorder Bardet-Biedl syndrome, is a novel centrosomal component required for cytokinesis. J Cell Sci (2005) 1.73
TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone. Am J Hum Genet (2011) 1.65
The interaction network of the chaperonin CCT. EMBO J (2008) 1.63
The sensory cilia of Caenorhabditis elegans. WormBook (2007) 1.61
Defects in the IFT-B component IFT172 cause Jeune and Mainzer-Saldino syndromes in humans. Am J Hum Genet (2013) 1.51
The WD repeat-containing protein IFTA-1 is required for retrograde intraflagellar transport. Mol Biol Cell (2006) 1.42
The roles of evolutionarily conserved functional modules in cilia-related trafficking. Nat Cell Biol (2013) 1.42
Loss of Bardet Biedl syndrome proteins causes defects in peripheral sensory innervation and function. Proc Natl Acad Sci U S A (2007) 1.32
Bardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signaling. J Biol Chem (2010) 1.28
Functional interactions between the ciliopathy-associated Meckel syndrome 1 (MKS1) protein and two novel MKS1-related (MKSR) proteins. J Cell Sci (2009) 1.26
Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics. Genome Biol (2006) 1.25
Quality control of cytoskeletal proteins and human disease. Trends Biochem Sci (2010) 1.17
PhLP3 modulates CCT-mediated actin and tubulin folding via ternary complexes with substrates. J Biol Chem (2006) 1.08
Caenorhabditis elegans DYF-2, an orthologue of human WDR19, is a component of the intraflagellar transport machinery in sensory cilia. Mol Biol Cell (2006) 1.08
Functional interaction between phosducin-like protein 2 and cytosolic chaperonin is essential for cytoskeletal protein function and cell cycle progression. Mol Biol Cell (2007) 1.06
An essential role for DYF-11/MIP-T3 in assembling functional intraflagellar transport complexes. PLoS Genet (2008) 1.06
Convergent evolution of clamp-like binding sites in diverse chaperones. Nat Struct Mol Biol (2006) 1.06
Divergent substrate-binding mechanisms reveal an evolutionary specialization of eukaryotic prefoldin compared to its archaeal counterpart. Structure (2007) 1.04
Getting a grip on non-native proteins. EMBO Rep (2003) 1.00
Efficient chaperone-mediated tubulin biogenesis is essential for cell division and cell migration in C. elegans. Dev Biol (2007) 0.99
Molecular clamp mechanism of substrate binding by hydrophobic coiled-coil residues of the archaeal chaperone prefoldin. Proc Natl Acad Sci U S A (2004) 0.96
Transcriptional profiling of C. elegans DAF-19 uncovers a ciliary base-associated protein and a CDK/CCRK/LF2p-related kinase required for intraflagellar transport. Dev Biol (2011) 0.94
Ciliogenesis in Caenorhabditis elegans requires genetic interactions between ciliary middle segment localized NPHP-2 (inversin) and transition zone-associated proteins. J Cell Sci (2012) 0.94
A truncating mutation of Alms1 reduces the number of hypothalamic neuronal cilia in obese mice. Dev Neurobiol (2012) 0.92
Striated rootlet and nonfilamentous forms of rootletin maintain ciliary function. Curr Biol (2013) 0.91
Sensorium: the original raison d'etre of the motile cilium? J Mol Cell Biol (2009) 0.87
Signaling proteins that regulate NaCl [corrected] chemotaxis responses modulate longevity in C. elegans. Ann N Y Acad Sci (2009) 0.87
Functional genomics of intraflagellar transport-associated proteins in C. elegans. Methods Cell Biol (2009) 0.84
Mutations in a guanylate cyclase GCY-35/GCY-36 modify Bardet-Biedl syndrome-associated phenotypes in Caenorhabditis elegans. PLoS Genet (2011) 0.83
Human prefoldin inhibits amyloid-β (Aβ) fibrillation and contributes to formation of nontoxic Aβ aggregates. Biochemistry (2013) 0.83
Localization of a guanylyl cyclase to chemosensory cilia requires the novel ciliary MYND domain protein DAF-25. PLoS Genet (2010) 0.81
Identification of 526 conserved metazoan genetic innovations exposes a new role for cofactor E-like in neuronal microtubule homeostasis. PLoS Genet (2013) 0.77