A R Hawkins

Author PubWeight™ 65.43‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The isolation and nucleotide sequence of the complex AROM locus of Aspergillus nidulans. Nucleic Acids Res 1986 1.78
2 Chloramphenicol acetyltransferase gene of staphylococcal plasmid pC221. Nucleotide sequence analysis and expression studies. FEBS Lett 1985 1.73
3 Hollow waveguides with low intrinsic photoluminescence fabricated with Ta(2)O(5) and SiO(2) films. Appl Phys Lett 2011 1.46
4 Structure of dehydroquinate synthase reveals an active site capable of multistep catalysis. Nature 1998 1.41
5 The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases. EMBO J 2001 1.31
6 The two types of 3-dehydroquinase have distinct structures but catalyze the same overall reaction. Nat Struct Biol 1999 1.25
7 Isolation and characterization of the positively acting regulatory gene QUTA from Aspergillus nidulans. Nucleic Acids Res 1987 1.25
8 Loss-based optical trap for on-chip particle analysis. Lab Chip 2009 1.23
9 Nucleotide sequence encoding the biosynthetic dehydroquinase function of the penta-functional arom locus of Aspergillus nidulans. Nucleic Acids Res 1985 1.22
10 Genetical and biochemical aspects of quinate breakdown in the filamentous fungus Aspergillus nidulans. Biochem Genet 1982 1.21
11 Cloning and expression in Escherichia coli K-12 of the biosynthetic dehydroquinase function of the arom cluster gene from the eucaryote, Aspergillus nidulans. Mol Gen Genet 1982 1.20
12 A comparison of the enzymological and biophysical properties of two distinct classes of dehydroquinase enzymes. Biochem J 1992 1.19
13 Isolation, characterization and nucleotide sequences of the aroC genes encoding chorismate synthase from Salmonella typhi and Escherichia coli. J Gen Microbiol 1990 1.13
14 Ultrasensitive Qbeta phage analysis using fluorescence correlation spectroscopy on an optofluidic chip. Biosens Bioelectron 2009 1.13
15 Spatial and biological characterisation of the complete quinic acid utilisation gene cluster in Aspergillus nidulans. Mol Gen Genet 1990 1.12
16 Genetic regulation of the quinic acid utilization (QUT) gene cluster in Aspergillus nidulans. J Gen Microbiol 1988 1.11
17 Sequence analysis and transformation by the catabolic 3-dehydroquinase (QUTE) gene from Aspergillus nidulans. Biochem J 1986 1.10
18 Structural characterization of Salmonella typhimurium YeaZ, an M22 O-sialoglycoprotein endopeptidase homolog. Proteins 2006 1.09
19 Evidence for two control genes regulating expression of the quinic acid utilization (qut) gene cluster in Aspergillus nidulans. J Gen Microbiol 1984 1.06
20 Microphotonic control of single molecule fluorescence correlation spectroscopy using planar optofluidics. Opt Express 2007 1.06
21 Differential flux through the quinate and shikimate pathways. Implications for the channelling hypothesis. Biochem J 1992 1.05
22 Identification and isolation of a putative permease gene in the quinic acid utilization (QUT) gene cluster of Aspergillus nidulans. Curr Genet 1987 1.03
23 Planar thin film device for capillary electrophoresis. Lab Chip 2005 1.01
24 Ultralow power trapping and fluorescence detection of single particles on an optofluidic chip. Lab Chip 2009 0.99
25 Evidence from kinetic isotope studies for an enolate intermediate in the mechanism of type II dehydroquinases. Biochem J 1996 0.98
26 Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP78. Br J Cancer 2013 0.97
27 Nucleotide sequence analysis and overexpression of the gene encoding a type III chloramphenicol acetyltransferase. Biochem J 1988 0.96
28 In vivo overproduction of the pentafunctional arom polypeptide in Aspergillus nidulans affects metabolic flux in the quinate pathway. Mol Gen Genet 1991 0.95
29 Characterization of Neurospora crassa catabolic dehydroquinase purified from N. crassa and Escherichia coli. Biochem J 1982 0.95
30 Control of metabolic flux through the quinate pathway in Aspergillus nidulans. Biochem J 1996 0.95
31 The Aspergillus niger niaD gene encoding nitrate reductase: upstream nucleotide and amino acid sequence comparisons. Gene 1992 0.94
32 Comparison of ligand-induced conformational changes and domain closure mechanisms, between prokaryotic and eukaryotic dehydroquinate synthases. J Mol Biol 2004 0.93
33 Inducible overproduction of the Aspergillus nidulans pentafunctional AROM protein and the type-I and -II 3-dehydroquinases from Salmonella typhi and Mycobacterium tuberculosis. Biochem J 1992 0.93
34 Overproduction in Escherichia coli of the dehydroquinate synthase domain of the Aspergillus nidulans pentafunctional AROM protein. Biochem J 1992 0.91
35 Crystal structure of the dimer of two essential Salmonella typhimurium proteins, YgjD & YeaZ and calorimetric evidence for the formation of a ternary YgjD-YeaZ-YjeE complex. Protein Sci 2013 0.91
36 The QUTA activator and QUTR repressor proteins of Aspergillus nidulans interact to regulate transcription of the quinate utilization pathway genese. Microbiology 1996 0.90
37 Characterization of the type I dehydroquinase from Salmonella typhi. Biochem J 1993 0.90
38 Actin in the oomycetous fungus Phytophthora infestans is the product of several genes. Gene 1991 0.90
39 Mechanistic studies on type I and type II dehydroquinase with (6R)- and (6S)-6-fluoro-3-dehydroquinic acids. Bioorg Med Chem Lett 2000 0.90
40 Selective overexpression of the QUTE gene encoding catabolic 3-dehydroquinase in multicopy transformants of Aspergillus nidulans. Biochem J 1990 0.87
41 High-resolution structures reveal details of domain closure and "half-of-sites-reactivity" in Escherichia coli aspartate beta-semialdehyde dehydrogenase. J Mol Biol 2004 0.87
42 Dual-color fluorescence cross-correlation spectroscopy on a planar optofluidic chip. Lab Chip 2011 0.86
43 Crystallization of a type I 3-dehydroquinase from Salmonella typhi. J Mol Biol 1992 0.85
44 Structure of the ribosomal interacting GTPase YjeQ from the enterobacterial species Salmonella typhimurium. Acta Crystallogr Sect F Struct Biol Cryst Commun 2007 0.85
45 Efficient independent activity of a monomeric, monofunctional dehydroquinate synthase derived from the N-terminus of the pentafunctional AROM protein of Aspergillus nidulans. Biochem J 1994 0.85
46 Crystallization of a type II dehydroquinase from Mycobacterium tuberculosis. J Mol Biol 1994 0.85
47 Structure of the 'open' form of Aspergillus nidulans 3-dehydroquinate synthase at 1.7 A resolution from crystals grown following enzyme turnover. Acta Crystallogr D Biol Crystallogr 2004 0.85
48 Optofluidic particle concentration by a long-range dual-beam trap. Opt Lett 2009 0.84
49 Ligand-induced conformational changes and a mechanism for domain closure in Aspergillus nidulans dehydroquinate synthase. J Mol Biol 2003 0.84
50 Crystal structures of Staphylococcus aureus type I dehydroquinase from enzyme turnover experiments. Proteins 2004 0.84
51 Overproduction of, and interaction within, bifunctional domains from the amino- and carboxy-termini of the pentafunctional AROM protein of Aspergillus nidulans. Mol Gen Genet 1993 0.83
52 A single DNA-binding protein from Pseudomonas aeruginosa homologous to proteins NS1 and NS2 (HU proteins) of Escherichia coli and other bacteria. FEBS Lett 1981 0.83
53 Crystallization and preliminary X-ray analysis of the human respiratory syncytial virus nucleocapsid protein. Acta Crystallogr Sect F Struct Biol Cryst Commun 2008 0.83
54 Prediction of recurrence after mastectomy for operable breast cancer. Br J Surg 1985 0.82
55 Sequence of the Phytophthora infestans glyceraldehyde-3-phosphate dehydrogenase-encoding gene (gpdA). Plant Mol Biol 1992 0.82
56 Conformational changes and the role of metals in the mechanism of type II dehydroquinase from Aspergillus nidulans. Biochem J 1996 0.82
57 Domain structure and function within the QUTA protein of Aspergillus nidulans: implications for the control of transcription. Microbiology 1996 0.81
58 Isolation and identification of the Aspergillus nidulans gdhA gene encoding NADP-linked glutamate dehydrogenase. Curr Genet 1986 0.81
59 Expression, purification and crystallization of Aspergillus nidulans NmrA, a negative regulatory protein involved in nitrogen-metabolite repression. Acta Crystallogr D Biol Crystallogr 2001 0.81
60 Structures of respiratory syncytial virus nucleocapsid protein from two crystal forms: details of potential packing interactions in the native helical form. Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 0.81
61 Twists and turns: a tale of two shikimate-pathway enzymes. Biochem Soc Trans 2003 0.80
62 Deletion of the N-terminal region of the AREA protein is correlated with a derepressed phenotype with respect to nitrogen metabolite repression. J Bacteriol 1997 0.79
63 A second gene (qutH) within the Aspergillus nidulans-quinic-acid utilisation gene cluster encodes a protein with a putative zinc-cluster motif. Gene 1992 0.79
64 The folding and assembly of the dodecameric type II dehydroquinases. Biochem J 1999 0.78
65 Identification of many crystal forms of Aspergillus nidulans dehydroquinate synthase. Acta Crystallogr D Biol Crystallogr 2001 0.78
66 Comparative analysis of the QUTR transcription repressor protein and the three C-terminal domains of the pentafunctional AROM enzyme. Biochem J 1996 0.77
67 Identification of domains responsible for signal recognition and transduction within the QUTR transcription repressor protein. Biochem J 2000 0.75
68 Dehydroquinate synthase binds divalent and trivalent cations: role of metal binding in catalysis. Biochem Soc Trans 1997 0.75
69 The slow step of folding of Staphylococcus aureus PC1 beta-lactamase involves the collapse of a surface loop rate limited by the trans to cis isomerization of a non-proline peptide bond. Proteins 1998 0.75
70 Analysis of the effect of an electric-field profile on the gain bandwidth product of avalanche photodetectors. Opt Lett 1997 0.75
71 Centralizing supplies saves lives. Occup Health Saf 1989 0.75