Published in Cancer Prev Res (Phila) on June 22, 2010
Epidermal growth factor receptor expression and gene copy number in the risk of oral cancer. Cancer Prev Res (Phila) (2010) 1.80
Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science (2011) 11.12
TP53 mutations and survival in squamous-cell carcinoma of the head and neck. N Engl J Med (2007) 5.92
BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer. J Clin Endocrinol Metab (2005) 4.39
Trends in incidence and prognosis for head and neck cancer in the United States: a site-specific analysis of the SEER database. Int J Cancer (2005) 3.27
Alcohol consumption and expenditures for underage drinking and adult excessive drinking. JAMA (2003) 2.59
MicroRNA alterations in head and neck squamous cell carcinoma. Int J Cancer (2008) 2.56
Impact of pharyngeal closure technique on fistula after salvage laryngectomy. JAMA Otolaryngol Head Neck Surg (2013) 2.37
Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells. J Biol Chem (2008) 2.07
DNA global hypomethylation in squamous cell head and neck cancer associated with smoking, alcohol consumption and stage. Int J Cancer (2007) 1.97
Mitochondrial C-tract alteration in premalignant lesions of the head and neck: a marker for progression and clonal proliferation. Clin Cancer Res (2002) 1.97
Cystic lymph node metastasis in patients with head and neck cancer: An HPV-associated phenomenon. Head Neck (2008) 1.97
Inverse correlation between cyclin A1 hypermethylation and p53 mutation in head and neck cancer identified by reversal of epigenetic silencing. Cancer Res (2004) 1.74
Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck. Proc Natl Acad Sci U S A (2007) 1.68
Consensus statement on the classification and terminology of neck dissection. Arch Otolaryngol Head Neck Surg (2008) 1.68
Endothelin receptor type B gene promoter hypermethylation in salivary rinses is independently associated with risk of oral cavity cancer and premalignancy. Cancer Prev Res (Phila) (2010) 1.68
Mitochondrial mutations are a late event in the progression of head and neck squamous cell cancer. Clin Cancer Res (2007) 1.62
Evaluation of promoter hypermethylation detection in body fluids as a screening/diagnosis tool for head and neck squamous cell carcinoma. Clin Cancer Res (2008) 1.62
Promoter methylation and inactivation of tumour-suppressor genes in oral squamous-cell carcinoma. Lancet Oncol (2006) 1.61
The molecular biology of mucosal field cancerization of the head and neck. Crit Rev Oral Biol Med (2003) 1.58
Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer. Int J Cancer (2006) 1.56
Quantitative detection of Merkel cell virus in human tissues and possible mode of transmission. Int J Cancer (2010) 1.53
Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity. Clin Cancer Res (2002) 1.53
DeltaNp63alpha up-regulates the Hsp70 gene in human cancer. Cancer Res (2005) 1.44
Serum microRNA biomarkers for detection of non-small cell lung cancer. PLoS One (2012) 1.43
Mitochondrial DNA quantity increases with histopathologic grade in premalignant and malignant head and neck lesions. Clin Cancer Res (2004) 1.37
The role of human papillomavirus in oral carcinogenesis. Crit Rev Oral Biol Med (2004) 1.31
Presence of HPV DNA in convalescent salivary rinses is an adverse prognostic marker in head and neck squamous cell carcinoma. Oral Oncol (2008) 1.29
TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization. Clin Cancer Res (2010) 1.27
Identification of hypermethylated genes associated with cisplatin resistance in human cancers. Cancer Res (2010) 1.26
KIF1A and EDNRB are differentially methylated in primary HNSCC and salivary rinses. Int J Cancer (2010) 1.26
Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma. Clin Cancer Res (2009) 1.24
Overexpression of AQP5, a putative oncogene, promotes cell growth and transformation. Cancer Lett (2008) 1.23
Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma. Cancer Res (2006) 1.22
Methylation of the thyroid-stimulating hormone receptor gene in epithelial thyroid tumors: a marker of malignancy and a cause of gene silencing. Cancer Res (2003) 1.20
Value of chest CT in the diagnosis and management of tracheobronchial foreign bodies. Pediatr Int (2011) 1.16
Activation of the NOTCH pathway in head and neck cancer. Cancer Res (2013) 1.15
Integrative discovery of epigenetically derepressed cancer testis antigens in NSCLC. PLoS One (2009) 1.14
An epigenetic marker panel for detection of lung cancer using cell-free serum DNA. Clin Cancer Res (2011) 1.13
Promoter methylation in head and neck squamous cell carcinoma cell lines is significantly different than methylation in primary tumors and xenografts. PLoS One (2011) 1.12
p53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma. Oral Oncol (2010) 1.10
Integrated, genome-wide screening for hypomethylated oncogenes in salivary gland adenoid cystic carcinoma. Clin Cancer Res (2011) 1.09
A survey of methylated candidate tumor suppressor genes in nasopharyngeal carcinoma. Int J Cancer (2011) 1.08
Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: a biomarker for the early detection of cancer. Mol Cancer (2006) 1.08
A new American Joint Committee on Cancer staging system for cutaneous squamous cell carcinoma: creation and rationale for inclusion of tumor (T) characteristics. J Am Acad Dermatol (2011) 1.06
Methylation of the DFNA5 increases risk of lymph node metastasis in human breast cancer. Biochem Biophys Res Commun (2008) 1.05
Identification of genes differentially expressed in benign versus malignant thyroid tumors. Clin Cancer Res (2008) 1.05
Molecular pathology of head-and-neck cancer. Int J Cancer (2004) 1.05
Intraoperative molecular margin analysis in head and neck cancer. Arch Otolaryngol Head Neck Surg (2004) 1.04
Detection of promoter hypermethylation in salivary rinses as a biomarker for head and neck squamous cell carcinoma surveillance. Clin Cancer Res (2011) 1.04
Advances and Perspectives in the Molecular Diagnosis of Head and Neck Cancer. Expert Opin Med Diagn (2010) 1.03
Serum protein MALDI profiling to distinguish upper aerodigestive tract cancer patients from control subjects. J Natl Cancer Inst (2003) 1.03
Combination effects of salvianolic acid B with low-dose celecoxib on inhibition of head and neck squamous cell carcinoma growth in vitro and in vivo. Cancer Prev Res (Phila) (2010) 1.03
The gastrointestinal manifestations of telomere-mediated disease. Aging Cell (2013) 1.00
Increased expression and activity of repair genes TDP1 and XPF in non-small cell lung cancer. Lung Cancer (2006) 1.00
Recurrence patterns and management of oral cavity premalignant lesions. Oral Oncol (2013) 1.00
EDNRB and DCC salivary rinse hypermethylation has a similar performance as expert clinical examination in discrimination of oral cancer/dysplasia versus benign lesions. Clin Cancer Res (2013) 0.99
DCC promoter hypermethylation in esophageal squamous cell carcinoma. Int J Cancer (2008) 0.98
Detection of TIMP3 promoter hypermethylation in salivary rinse as an independent predictor of local recurrence-free survival in head and neck cancer. Clin Cancer Res (2012) 0.97
Applying the molecular biology and epigenetics of head and neck cancer in everyday clinical practice. Oral Oncol (2008) 0.97
Molecular techniques and genetic alterations in head and neck cancer. Oral Oncol (2008) 0.96
Suprabasin is hypomethylated and associated with metastasis in salivary adenoid cystic carcinoma. PLoS One (2012) 0.96
Vitamin E succinate induces ceramide-mediated apoptosis in head and neck squamous cell carcinoma in vitro and in vivo. Clin Cancer Res (2008) 0.96
Decreased mitochondrial DNA content in posttreatment salivary rinses from head and neck cancer patients. Clin Cancer Res (2006) 0.96
The Ligamp TP53 Assay for Detection of Minimal Residual Disease in Head and Neck Squamous Cell Carcinoma Surgical Margins. Clin Cancer Res (2009) 0.95
Mitochondrial DNA mutation in normal margins and tumors of recurrent head and neck squamous cell carcinoma patients. Cancer Prev Res (Phila) (2010) 0.95
Estimate of the commercial value of underage drinking and adult abusive and dependent drinking to the alcohol industry. Arch Pediatr Adolesc Med (2006) 0.95
Quantitative methylation profiles for multiple tumor suppressor gene promoters in salivary gland tumors. PLoS One (2010) 0.95
The role of pre-operative CT-guided FNAB for parapharyngeal space tumors. Otolaryngol Head Neck Surg (2007) 0.94
Cigarette smoke induces promoter methylation of single-stranded DNA-binding protein 2 in human esophageal squamous cell carcinoma. Int J Cancer (2011) 0.93
BORIS binding to the promoters of cancer testis antigens, MAGEA2, MAGEA3, and MAGEA4, is associated with their transcriptional activation in lung cancer. Clin Cancer Res (2011) 0.93
Promoter hypermethylation in Indian primary oral squamous cell carcinoma. Int J Cancer (2010) 0.92
Use of single nucleotide polymorphism arrays to identify a novel region of loss on chromosome 6q in squamous cell carcinomas of the oral cavity. Head Neck (2004) 0.91
ssDNA-binding protein 2 is frequently hypermethylated and suppresses cell growth in human prostate cancer. Clin Cancer Res (2008) 0.91
Inhibition of TGF-β enhances the in vivo antitumor efficacy of EGF receptor-targeted therapy. Mol Cancer Ther (2012) 0.90
Neck management in patients undergoing postradiotherapy salvage laryngeal surgery for recurrent/persistent laryngeal cancer. Laryngoscope (2006) 0.90
Real-time gap ligase chain reaction: a rapid semiquantitative assay for detecting p53 mutation at low levels in surgical margins and lymph nodes from resected lung and head and neck tumors. Clin Cancer Res (2004) 0.90
Transoral robotic surgery experience in 44 cases. J Laparoendosc Adv Surg Tech A (2013) 0.89
Progression of microsatellite instability from premalignant lesions to tumors of the head and neck. Int J Cancer (2002) 0.89
Evaluation of MYB promoter methylation in salivary adenoid cystic carcinoma. Oral Oncol (2011) 0.89
Improvement of prostate cancer detection by integrating the PSA test with miRNA expression profiling. Cancer Invest (2011) 0.89
Factors associated with pharyngoesophageal stricture in patients treated with concurrent chemotherapy and radiation therapy for oropharyngeal squamous cell carcinoma. Head Neck (2011) 0.89
Mitochondrial DNA alterations in thyroid cancer. J Surg Oncol (2003) 0.88
Death-associated protein kinase promoter hypermethylation in normal human lymphocytes. Cancer Res (2003) 0.88
EIF2C is overexpressed and amplified in head and neck squamous cell carcinoma. ORL J Otorhinolaryngol Relat Spec (2010) 0.87
Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands. PLoS One (2009) 0.87
Colorimetric approach to high-throughput mutation analysis. Biotechniques (2005) 0.87
Mitochondrial resequencing arrays detect tumor-specific mutations in salivary rinses of patients with head and neck cancer. Clin Cancer Res (2007) 0.87
Epstein-Barr virus in head and neck cancer assessed by quantitative polymerase chain reaction. Laryngoscope (2004) 0.87
Supracricoid laryngectomy outcomes: The Johns Hopkins experience. Laryngoscope (2007) 0.86
Head and neck cancer cell lines exhibit differential mitochondrial repair deficiency in response to 4NQO. Oral Oncol (2005) 0.86
Short hospital stay after neck dissection. Otolaryngol Head Neck Surg (2005) 0.85
Inactivation of the tumor suppressor genes causing the hereditary syndromes predisposing to head and neck cancer via promoter hypermethylation in sporadic head and neck cancers. ORL J Otorhinolaryngol Relat Spec (2010) 0.85
Transoral robotic surgery of the vocal cord. J Laparoendosc Adv Surg Tech A (2011) 0.84
MAGEB2 is activated by promoter demethylation in head and neck squamous cell carcinoma. PLoS One (2012) 0.84
Dose-dependent activation of putative oncogene SBSN by BORIS. PLoS One (2012) 0.84
Novel integrative methods for gene discovery associated with head and neck squamous cell carcinoma development. Arch Otolaryngol Head Neck Surg (2009) 0.84
Spindle assembly checkpoint defects and chromosomal instability in head and neck squamous cell carcinoma. Int J Cancer (2003) 0.83
Preferential activation of the hedgehog pathway by epigenetic modulations in HPV negative HNSCC identified with meta-pathway analysis. PLoS One (2013) 0.83
Sequencing the head and neck cancer genome: implications for therapy. Ann N Y Acad Sci (2014) 0.83