| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: a randomised, double-blind study.
|
Lancet
|
2011
|
11.28
|
|
2
|
Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind study.
|
J Clin Oncol
|
2010
|
9.29
|
|
3
|
Randomized, double-blind study of denosumab versus zoledronic acid in the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma.
|
J Clin Oncol
|
2011
|
6.16
|
|
4
|
hDOT1L links histone methylation to leukemogenesis.
|
Cell
|
2005
|
5.83
|
|
5
|
Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L.
|
Nat Cell Biol
|
2006
|
1.97
|
|
6
|
Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease.
|
Blood
|
2005
|
1.89
|
|
7
|
1.3-μm InAs/GaAs quantum-dot lasers monolithically grown on Si substrates using InAlAs/GaAs dislocation filter layers.
|
Opt Express
|
2014
|
1.82
|
|
8
|
Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition.
|
J Clin Invest
|
2010
|
1.74
|
|
9
|
The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis.
|
J Exp Med
|
2005
|
1.70
|
|
10
|
Bone-related complications and quality of life in advanced breast cancer: results from a randomized phase III trial of denosumab versus zoledronic acid.
|
Clin Cancer Res
|
2012
|
1.26
|
|
11
|
Preservation of effect and the regulatory approval of new treatments on the basis of non-inferiority trials.
|
Stat Med
|
2008
|
1.18
|
|
12
|
Foxp3 and Treg cells in HIV-1 infection and immuno-pathogenesis.
|
Immunol Res
|
2008
|
1.11
|
|
13
|
Endothelial cells enhance prostate cancer metastasis via IL-6→androgen receptor→TGF-β→MMP-9 signals.
|
Mol Cancer Ther
|
2013
|
1.10
|
|
14
|
Elevated serum polybrominated diphenyl ethers and thyroid-stimulating hormone associated with lymphocytic micronuclei in Chinese workers from an E-waste dismantling site.
|
Environ Sci Technol
|
2008
|
1.08
|
|
15
|
A genetic approach to inactivating chemokine receptors using a modified viral protein.
|
Nat Biotechnol
|
2003
|
1.07
|
|
16
|
On the clinical meaningfulness of a treatment's effect on a time-to-event variable.
|
Stat Med
|
2011
|
1.07
|
|
17
|
New therapy targeting differential androgen receptor signaling in prostate cancer stem/progenitor vs. non-stem/progenitor cells.
|
J Mol Cell Biol
|
2012
|
1.07
|
|
18
|
Evolution of the HIV-1 env gene in the Rag2-/- gammaC-/- humanized mouse model.
|
J Virol
|
2009
|
1.05
|
|
19
|
Responder analyses and the assessment of a clinically relevant treatment effect.
|
Trials
|
2007
|
0.99
|
|
20
|
Increased infiltrated macrophages in benign prostatic hyperplasia (BPH): role of stromal androgen receptor in macrophage-induced prostate stromal cell proliferation.
|
J Biol Chem
|
2012
|
0.99
|
|
21
|
Pain outcomes in patients with advanced breast cancer and bone metastases: results from a randomized, double-blind study of denosumab and zoledronic acid.
|
Cancer
|
2012
|
0.99
|
|
22
|
Ertapenem versus ceftriaxone followed by appropriate oral therapy for treatment of complicated urinary tract infections in adults: results of a prospective, randomized, double-blind multicenter study.
|
Antimicrob Agents Chemother
|
2002
|
0.96
|
|
23
|
Relevance of serum estradiol and estrogen receptor beta expression from a high-incidence area for esophageal squamous cell carcinoma in China.
|
Med Oncol
|
2010
|
0.96
|
|
24
|
Efficient infection, activation, and impairment of pDCs in the BM and peripheral lymphoid organs during early HIV-1 infection in humanized rag2⁻/⁻γ C⁻/⁻ mice in vivo.
|
Blood
|
2011
|
0.96
|
|
25
|
An overview of prostate diseases and their characteristics specific to Asian men.
|
Asian J Androl
|
2012
|
0.96
|
|
26
|
Unique sodium phosphosilicate glasses designed through extended topological constraint theory.
|
J Phys Chem B
|
2014
|
0.95
|
|
27
|
Targeting androgen receptor to suppress macrophage-induced EMT and benign prostatic hyperplasia (BPH) development.
|
Mol Endocrinol
|
2012
|
0.94
|
|
28
|
Assessment of futility in clinical trials.
|
Pharm Stat
|
2007
|
0.94
|
|
29
|
Persistent efficacy of live attenuated hepatitis A vaccine (H2-strain) after a mass vaccination program.
|
Chin Med J (Engl)
|
2005
|
0.92
|
|
30
|
Levofloxacin-containing triple and sequential therapy or standard sequential therapy as the first line treatment for Helicobacter pylori eradication in China.
|
Helicobacter
|
2012
|
0.92
|
|
31
|
Informative noncompliance in endpoint trials.
|
Curr Control Trials Cardiovasc Med
|
2004
|
0.89
|
|
32
|
Galpha13 mediates a signal that is essential for proliferation and survival of thymocyte progenitors.
|
J Exp Med
|
2004
|
0.88
|
|
33
|
A prospective, multicenter, randomized, double-blind study comparing ertapenem and ceftriaxone followed by appropriate oral therapy for complicated urinary tract infections in adults.
|
Urology
|
2002
|
0.88
|
|
34
|
Controlling the type 1 error rate in non-inferiority trials.
|
Stat Med
|
2008
|
0.87
|
|
35
|
Treatment of complicated urinary tract infection in adults: combined analysis of two randomized, double-blind, multicentre trials comparing ertapenem and ceftriaxone followed by appropriate oral therapy.
|
J Antimicrob Chemother
|
2004
|
0.86
|
|
36
|
Estimating minimally important differences for the worst pain rating of the Brief Pain Inventory-Short Form.
|
J Support Oncol
|
2011
|
0.85
|
|
37
|
Anti-depressant effects of aqueous extract from Acanthopanax senticosus in mice.
|
Phytother Res
|
2013
|
0.85
|
|
38
|
Fiber optic pressure sensing with conforming elastomers.
|
Appl Opt
|
2010
|
0.84
|
|
39
|
[Long-term immunogenicity and effectiveness of live attenuated hepatitis A vaccine (H2-strain)-a study on the result of 15 years' follow up].
|
Zhonghua Liu Xing Bing Xue Za Zhi
|
2010
|
0.84
|
|
40
|
Identifying early urinary metabolic changes with long-term environmental exposure to cadmium by mass-spectrometry-based metabolomics.
|
Environ Sci Technol
|
2014
|
0.84
|
|
41
|
In vitro protective effects of pyrroloquinoline quinone on methylmercury-induced neurotoxicity.
|
Environ Toxicol Pharmacol
|
2008
|
0.82
|
|
42
|
Primary stromal cells isolated from human various histological/pathological prostate have different phenotypes and tumor promotion role.
|
Chin Med J (Engl)
|
2011
|
0.82
|
|
43
|
Safety monitoring in clinical trials.
|
Pharmaceutics
|
2013
|
0.82
|
|
44
|
Zonal differences in prostate diseases.
|
Chin Med J (Engl)
|
2012
|
0.80
|
|
45
|
InAs/GaAsSb quantum dot solar cells.
|
Opt Express
|
2014
|
0.80
|
|
46
|
Protective effects of aqueous extract from Acanthopanax senticosus against corticosterone-induced neurotoxicity in PC12 cells.
|
J Ethnopharmacol
|
2013
|
0.79
|
|
47
|
A CAPE analogue as novel antiplatelet agent efficiently inhibits collagen-induced platelet aggregation.
|
Pharmazie
|
2014
|
0.79
|
|
48
|
Biomimetic peptoid oligomers as dual-action antifreeze agents.
|
Proc Natl Acad Sci U S A
|
2012
|
0.79
|
|
49
|
Inhibition of fatty-acid synthase suppresses P-AKT and induces apoptosis in bladder cancer.
|
Urology
|
2012
|
0.78
|
|
50
|
Predictive value of F-18 FDG PET/CT quantization parameters in diffuse large B cell lymphoma: a meta-analysis with 702 participants.
|
Med Oncol
|
2014
|
0.78
|
|
51
|
Safety and local tolerability of intramuscularly administered ertapenem diluted in lidocaine: a prospective, randomized, double-blind study versus intramuscular ceftriaxone.
|
Clin Ther
|
2002
|
0.78
|
|
52
|
Caspase-dependent molecular mechanisms of anti-human DR5 monoclonal antibody mDRA-6 inducing apoptosis of human leukemia Jurkat cells.
|
Ai Zheng
|
2009
|
0.77
|
|
53
|
A novel agonistic anti-human death receptor 5 monoclonal antibody with tumoricidal activity induces caspase- and mitochondrial-dependent apoptosis in human leukemia Jurkat cells.
|
Cancer Biother Radiopharm
|
2011
|
0.77
|
|
54
|
Indirect comparisons in the comparative efficacy and non-inferiority settings.
|
Pharm Stat
|
2011
|
0.77
|
|
55
|
Predicting analysis time in event-driven clinical trials with event-reporting lag.
|
Stat Med
|
2012
|
0.76
|
|
56
|
A counterfactual p-value approach for benefit-risk assessment in clinical trials.
|
J Biopharm Stat
|
2015
|
0.75
|
|
57
|
Androgen receptors expressed by prostatic stromal cells obtained from younger versus older males exhibit opposite roles in prostate cancer progression.
|
Asian J Androl
|
2013
|
0.75
|
|
58
|
The role of urethral pressure profile on treating premature ejaculation by tamsulosin.
|
Asian J Androl
|
2014
|
0.75
|
|
59
|
InAs/GaAs quantum-dot superluminescent diodes monolithically grown on a Ge substrate.
|
Opt Express
|
2014
|
0.75
|
|
60
|
Effects of extracellular environment factors on the motility in Japanese eel spermatozoa.
|
Cell Biol Int
|
2011
|
0.75
|
|
61
|
[Analysis of the impact of two typical air pollution events on the air quality of Nanjing].
|
Huan Jing Ke Xue
|
2012
|
0.75
|
|
62
|
In situ annealing enhancement of the optical properties and laser device performance of InAs quantum dots grown on Si substrates.
|
Opt Express
|
2016
|
0.75
|
|
63
|
[Clinical observational study of anemia in mechanically ventilated patients].
|
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
|
2012
|
0.75
|
|
64
|
[Characterization of stromal cell cultures from the prostatic peripheral zone of men at different ages].
|
Zhonghua Nan Ke Xue
|
2011
|
0.75
|
|
65
|
[Impacts of ultraviolet irradiation on the sperm motility and longevity of Acipenser baerii].
|
Ying Yong Sheng Tai Xue Bao
|
2011
|
0.75
|
|
66
|
Continuous-wave InAs/GaAs quantum-dot laser diodes monolithically grown on Si substrate with low threshold current densities.
|
Opt Express
|
2012
|
0.75
|
|
67
|
Evaluation of statistical methods for safety signal detection: a simulation study.
|
Pharm Stat
|
2014
|
0.75
|
|
68
|
Analysis of multiple endpoints in clinical trials: it's time for the designations of primary, secondary and tertiary to go.
|
Pharm Stat
|
2011
|
0.75
|
|
69
|
[Polymorphisms of hsp 60 gene in Chinese Han people].
|
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
|
2006
|
0.75
|
|
70
|
The issue of multiplicity in noninferiority studies.
|
Clin Trials
|
2012
|
0.75
|
|
71
|
A Contemporary Assessment of Acute Mechanical Ventilation in Beijing: Description, Costs, and Outcomes.
|
Crit Care Med
|
2017
|
0.75
|
|
72
|
[Spatial distribution of three endocrine disrupting chemicals in sediments of the Suzhou Creek and their environmental risks].
|
Huan Jing Ke Xue
|
2012
|
0.75
|
|
73
|
[Research on cytokines gene express of rats alcoholic liver disease affected by tea polyphenol].
|
Zhongguo Zhong Yao Za Zhi
|
2005
|
0.75
|