PubRank

Andrew D Miranker

Author PubWeight™ 44.92‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Phospholipid catalysis of diabetic amyloid assembly. J Mol Biol 2004 2.46
2 Islet amyloid: phase partitioning and secondary nucleation are central to the mechanism of fibrillogenesis. Biochemistry 2002 2.44
3 Conserved and cooperative assembly of membrane-bound alpha-helical states of islet amyloid polypeptide. Biochemistry 2006 2.25
4 A native to amyloidogenic transition regulated by a backbone trigger. Nat Struct Mol Biol 2006 2.20
5 Fiber-dependent amyloid formation as catalysis of an existing reaction pathway. Proc Natl Acad Sci U S A 2007 1.75
6 Direct detection of transient alpha-helical states in islet amyloid polypeptide. Protein Sci 2006 1.74
7 The interplay of catalysis and toxicity by amyloid intermediates on lipid bilayers: insights from type II diabetes. Annu Rev Biophys 2009 1.72
8 Helix stabilization precedes aqueous and bilayer-catalyzed fiber formation in islet amyloid polypeptide. J Mol Biol 2009 1.53
9 Oligomeric assembly of native-like precursors precedes amyloid formation by beta-2 microglobulin. Biochemistry 2004 1.53
10 Islet amyloid polypeptide demonstrates a persistent capacity to disrupt membrane integrity. Proc Natl Acad Sci U S A 2011 1.37
11 Protein-induced photophysical changes to the amyloid indicator dye thioflavin T. Proc Natl Acad Sci U S A 2010 1.35
12 The mechanism of insulin action on islet amyloid polypeptide fiber formation. J Mol Biol 2004 1.31
13 A regulatable switch mediates self-association in an immunoglobulin fold. Nat Struct Mol Biol 2008 1.30
14 Formation of a copper specific binding site in non-native states of beta-2-microglobulin. Biochemistry 2002 1.28
15 A peptidomimetic approach to targeting pre-amyloidogenic states in type II diabetes. Chem Biol 2009 1.18
16 Single-molecule fluorescence spectroscopy using phospholipid bilayer nanodiscs. Methods Enzymol 2010 1.17
17 Common mechanism unites membrane poration by amyloid and antimicrobial peptides. Proc Natl Acad Sci U S A 2013 1.16
18 Concentration-dependent transitions govern the subcellular localization of islet amyloid polypeptide. FASEB J 2011 1.14
19 Synthetic alpha-helix mimetics as agonists and antagonists of islet amyloid polypeptide aggregation. Angew Chem Int Ed Engl 2010 1.11
20 Contribution of the intrinsic disulfide to the assembly mechanism of islet amyloid. Protein Sci 2004 1.09
21 Amide inequivalence in the fibrillar assembly of islet amyloid polypeptide. Protein Eng Des Sel 2008 1.07
22 Interaction of membrane-bound islet amyloid polypeptide with soluble and crystalline insulin. Protein Sci 2008 1.06
23 Formation of a stable oligomer of beta-2 microglobulin requires only transient encounter with Cu(II). J Mol Biol 2006 1.00
24 Metal binding sheds light on mechanisms of amyloid assembly. Prion 2009 0.99
25 From chance to frequent encounters: origins of beta2-microglobulin fibrillogenesis. Biochim Biophys Acta 2005 0.99
26 A membrane-bound antiparallel dimer of rat islet amyloid polypeptide. Angew Chem Int Ed Engl 2011 0.95
27 A foldamer approach to targeting membrane bound helical states of islet amyloid polypeptide. Chem Commun (Camb) 2013 0.89
28 Delineating the conformational elements responsible for Cu(2+)-induced oligomerization of beta-2 microglobulin. Biochemistry 2009 0.85
29 The role of prefibrillar structures in the assembly of a peptide amyloid. J Mol Biol 2009 0.85
30 A common landscape for membrane-active peptides. Protein Sci 2013 0.83
31 Scope and utility of hydrogen exchange as a tool for mapping landscapes. Protein Sci 2007 0.83
32 Small molecule screening in context: lipid-catalyzed amyloid formation. Protein Sci 2014 0.82
33 Structural biology: fibres hinge on swapped domains. Nature 2005 0.79
34 Peptide amyloid surface display. Biochemistry 2015 0.78
35 Protein aggregation: p53 succumbs to peer pressure. Nat Chem Biol 2011 0.75
36 Foldamer scaffolds suggest distinct structures are associated with alternative gains-of-function in a preamyloid toxin. Chem Commun (Camb) 2016 0.75