Alessandro Gronchi

Author PubWeight™ 114.16‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A new mutation in the KIT ATP pocket causes acquired resistance to imatinib in a gastrointestinal stromal tumor patient. Gastroenterology 2004 3.61
2 NCCN Task Force report: management of patients with gastrointestinal stromal tumor (GIST)--update of the NCCN clinical practice guidelines. J Natl Compr Canc Netw 2007 3.40
3 Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study. Lancet Oncol 2007 3.38
4 Malignant peripheral nerve sheath tumors: prognostic factors and survival in a series of patients treated at a single institution. Cancer 2006 2.98
5 Desmoid-type fibromatosis: a front-line conservative approach to select patients for surgical treatment. Ann Surg Oncol 2009 2.48
6 Synovial sarcoma: a retrospective analysis of 271 patients of all ages treated at a single institution. Cancer 2004 2.46
7 Rhabdomyosarcoma in adults. A retrospective analysis of 171 patients treated at a single institution. Cancer 2003 2.11
8 Imatinib mesylate in chordoma. Cancer 2004 1.94
9 Phase II study of imatinib in advanced chordoma. J Clin Oncol 2012 1.89
10 Chordoma. Curr Opin Oncol 2007 1.75
11 Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells. Cancer Res 2010 1.68
12 Adult-type soft tissue sarcomas in pediatric-age patients: experience at the Istituto Nazionale Tumori in Milan. J Clin Oncol 2005 1.61
13 High-grade soft-tissue sarcomas: tumor response assessment--pilot study to assess the correlation between radiologic and pathologic response by using RECIST and Choi criteria. Radiology 2009 1.53
14 Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors. Mol Cancer Ther 2009 1.52
15 Validation and adaptation of a nomogram for predicting the survival of patients with extremity soft tissue sarcoma using a three-grade system. Cancer 2005 1.45
16 Telomere maintenance mechanisms in liposarcomas: association with histologic subtypes and disease progression. Cancer Res 2006 1.44
17 Therapeutic consequences from molecular biology for gastrointestinal stromal tumor patients affected by neurofibromatosis type 1. Clin Cancer Res 2008 1.43
18 Thoracopleuropneumonectomy with riblike reconstruction for recurrent thoracic sarcomas. Ann Surg Oncol 2014 1.40
19 Lack of SYT-SSX fusion transcripts in malignant peripheral nerve sheath tumors on RT-PCR analysis of 34 archival cases. Lab Invest 2002 1.40
20 Response to sunitinib malate in advanced alveolar soft part sarcoma. Clin Cancer Res 2009 1.39
21 Molecular and biochemical analyses of platelet-derived growth factor receptor (PDGFR) B, PDGFRA, and KIT receptors in chordomas. Clin Cancer Res 2006 1.35
22 Dermatofibrosarcoma protuberans treated at a single institution: a surgical disease with a high cure rate. J Clin Oncol 2005 1.32
23 Sunitinib malate and figitumumab in solitary fibrous tumor: patterns and molecular bases of tumor response. Mol Cancer Ther 2010 1.29
24 Aggressive surgery in retroperitoneal soft tissue sarcoma carried out at high-volume centers is safe and is associated with improved local control. Ann Surg Oncol 2010 1.28
25 Neoadjuvant imatinib in locally advanced gastrointestinal stromal tumors (GIST): the EORTC STBSG experience. Ann Surg Oncol 2013 1.28
26 Chordoma of the mobile spine and sacrum: a retrospective analysis of a series of patients surgically treated at two referral centers. Ann Surg Oncol 2009 1.28
27 Aggressive fibromatosis in children and adolescents: the Italian experience. Cancer 2010 1.27
28 Epithelioid sarcoma in children and adolescents: a report from the Italian Soft Tissue Sarcoma Committee. Cancer 2006 1.27
29 Myxoid/round cell and pleomorphic liposarcomas: prognostic factors and survival in a series of patients treated at a single institution. Cancer 2007 1.27
30 Prognostic effect of re-excision in adult soft tissue sarcoma of the extremity. Ann Surg Oncol 2006 1.27
31 Cyclooxygenase-2 and platelet-derived growth factor receptors as potential targets in treating aggressive fibromatosis. Clin Cancer Res 2007 1.21
32 p15INK4b, p14ARF, and p16INK4a inactivation in sporadic and neurofibromatosis type 1-related malignant peripheral nerve sheath tumors. Clin Cancer Res 2003 1.16
33 Gastrointestinal stromal tumor of the rectum: results of surgical and multimodality therapy in the era of imatinib. Ann Surg Oncol 2012 1.16
34 The prognostic impact of dedifferentiation in retroperitoneal liposarcoma: a series of surgically treated patients at a single institution. Cancer 2008 1.15
35 CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence: an independent, multicenter validation study. Cancer 2013 1.13
36 Natural history of imatinib-naive GISTs: a retrospective analysis of 929 cases with long-term follow-up and development of a survival nomogram based on mitotic index and size as continuous variables. Am J Surg Pathol 2011 1.12
37 Epithelioid sarcoma: prognostic factors and survival in a series of patients treated at a single institution. Ann Surg Oncol 2007 1.11
38 High-grade sarcomatous overgrowth in solitary fibrous tumors: a clinicopathologic study of 10 cases. Am J Surg Pathol 2012 1.11
39 Surgical technique, morbidity, and outcome of primary retroperitoneal sarcoma involving inferior vena cava. Ann Surg Oncol 2011 1.11
40 Myxofibrosarcoma: prognostic factors and survival in a series of patients treated at a single institution. Ann Surg Oncol 2010 1.09
41 Expression of ligand-activated KIT and platelet-derived growth factor receptor beta tyrosine kinase receptors in synovial sarcoma. Clin Cancer Res 2004 1.08
42 Dermatofibrosarcoma protuberans-derived fibrosarcoma: clinical history, biological profile and sensitivity to imatinib. Int J Cancer 2011 1.08
43 9p21 locus analysis in high-risk gastrointestinal stromal tumors characterized for c-kit and platelet-derived growth factor receptor alpha gene alterations. Cancer 2005 1.07
44 Analysis of receptor tyrosine kinases (RTKs) and downstream pathways in chordomas. Neuro Oncol 2010 1.04
45 PDGFRA, PDGFRB, EGFR, and downstream signaling activation in malignant peripheral nerve sheath tumor. Neuro Oncol 2009 1.04
46 Desmoid-type fibromatosis and pregnancy: a multi-institutional analysis of recurrence and obstetric risk. Ann Surg 2014 1.03
47 Current concepts and future perspectives in retroperitoneal soft-tissue sarcoma management. Expert Rev Anticancer Ther 2009 1.03
48 Carney triad: case report and molecular analysis of gastric tumor. Hum Pathol 2005 1.01
49 c-Kit/PDGFRA gene status alterations possibly related to primary imatinib resistance in gastrointestinal stromal tumors. Clin Cancer Res 2007 1.01
50 Alveolar soft part sarcoma: clinical presentation, treatment, and outcome in a series of 33 patients at a single institution. Ann Surg Oncol 2010 1.00
51 Hyperthermic intraperitoneal intraoperative chemotherapy after cytoreductive surgery for the treatment of abdominal sarcomatosis: clinical outcome and prognostic factors in 60 consecutive patients. Cancer 2004 0.99
52 Peritoneal sarcomatosis: is there a subset of patients who may benefit from cytoreductive surgery and hyperthermic intraperitoneal chemotherapy? Ann Surg Oncol 2010 0.98
53 Soft tissue sarcomas of childhood and adolescence: the prognostic role of tumor size in relation to patient body size. J Clin Oncol 2008 0.97
54 Spontaneous regression of primary abdominal wall desmoid tumors: more common than previously thought. Ann Surg Oncol 2013 0.97
55 Prognostic relevance of ALT-associated markers in liposarcoma: a comparative analysis. BMC Cancer 2010 0.96
56 Gastrointestinal stromal tumors I: pathology, pathobiology, primary therapy, and surgical issues. Semin Oncol 2009 0.95
57 Adult-type soft tissue sarcomas in paediatric age: a nomogram-based prognostic comparison with adult sarcoma. Eur J Cancer 2007 0.94
58 Tumor response assessment by modified Choi criteria in localized high-risk soft tissue sarcoma treated with chemotherapy. Cancer 2012 0.94
59 Desmoid-type fibromatosis: what works best? Eur J Cancer 2009 0.93
60 Novel models of myxoid liposarcoma xenografts mimicking the biological and pharmacologic features of human tumors. Clin Cancer Res 2010 0.93
61 Response to imatinib in villonodular pigmented synovitis (PVNS) resistant to nilotinib. Clin Sarcoma Res 2013 0.91
62 Anthracycline-based chemotherapy in extraskeletal myxoid chondrosarcoma: a retrospective study. Clin Sarcoma Res 2013 0.91
63 Soft-tissue sarcomas of the extremities in patients of pediatric age. J Child Orthop 2007 0.90
64 Adjuvant treatment of GIST with imatinib: solid ground or still quicksand? A comment on behalf of the EORTC Soft Tissue and Bone Sarcoma Group, the Italian Sarcoma Group, the NCRI Sarcoma Clinical Studies Group (UK), the Japanese Study Group on GIST, the French Sarcoma Group and the Spanish Sarcoma Group (GEIS). Eur J Cancer 2009 0.89
65 Prognostic determinants in epithelioid sarcoma. Eur J Cancer 2011 0.89
66 Prognostic factors and outcome of spermatic cord sarcoma. Ann Surg Oncol 2014 0.89
67 Extraskeletal myxoid chondrosarcoma: tumor response to sunitinib. Clin Sarcoma Res 2012 0.89
68 Emerging therapies for adult soft tissue sarcoma. Expert Rev Anticancer Ther 2014 0.88
69 Histology-specific nomogram for primary retroperitoneal soft tissue sarcoma. Cancer 2010 0.88
70 Technical considerations in surgery for retroperitoneal sarcomas: position paper from E-Surge, a master class in sarcoma surgery, and EORTC-STBSG. Ann Surg Oncol 2012 0.87
71 Sacral Chordoma: Long-term Outcome of a Large Series of Patients Surgically Treated at Two Reference Centers. Spine (Phila Pa 1976) 2016 0.87
72 Feasibility of peritonectomy associated with intraperitoneal hyperthermic perfusion in patients with Pseudomyxoma peritonei. Tumori 2002 0.86
73 Hyperthermia as an adjunctive treatment for soft-tissue sarcoma. Expert Rev Anticancer Ther 2009 0.86
74 Evidence of neural differentiation in a case of post-therapy primitive neuroectodermal tumor/Ewing sarcoma of bone. Am J Surg Pathol 2003 0.86
75 High CD133 expression levels in gastrointestinal stromal tumors. Cytometry B Clin Cytom 2011 0.83
76 KIT, PDGFRA, and BRAF mutational spectrum impacts on the natural history of imatinib-naive localized GIST: a population-based study. Am J Surg Pathol 2015 0.82
77 Receptor tyrosine kinase pathway analysis sheds light on similarities between clear-cell sarcoma and metastatic melanoma. Genes Chromosomes Cancer 2011 0.82
78 Is autophagy rather than apoptosis the regression driver in imatinib-treated gastrointestinal stromal tumors? Transl Oncol 2008 0.82
79 Activate and resist: L576P-KIT in GIST. Mol Cancer Ther 2009 0.82
80 Advanced extremity soft tissue sarcoma: prognostic effect of isolated limb perfusion in a series of 88 patients treated at a single institution. Ann Surg Oncol 2006 0.82
81 Postoperative Morbidity After Radical Resection of Primary Retroperitoneal Sarcoma: A Report From the Transatlantic RPS Working Group. Ann Surg 2017 0.82
82 Resection of uninvolved adjacent organs can be part of surgery for retroperitoneal soft tissue sarcoma. J Clin Oncol 2009 0.81
83 Localised thoracic sarcomas: outcome improvement over time at a single institution. Eur J Cancer 2013 0.81
84 Adjuvant therapy of gastrointestinal stromal tumors (GIST). Curr Treat Options Oncol 2012 0.81
85 Angiosarcoma of the breast and vascular endothelial growth factor receptor. Tumori 2011 0.81
86 Quality of local treatment or biology of the tumor: which are the trump cards for loco-regional control of retroperitoneal sarcoma? Ann Surg Oncol 2013 0.80
87 The combination of surgery and imatinib in GIST: a reality for localized tumors at high risk, an open issue for metastatic ones. Ann Surg Oncol 2012 0.80
88 In vitro and in silico studies of MDM2/MDMX isoforms predict Nutlin-3A sensitivity in well/de-differentiated liposarcomas. Lab Invest 2013 0.79
89 Surgery in retroperitoneal soft tissue sarcoma: a call for a consensus between Europe and North America. Ann Surg Oncol 2011 0.79
90 Gastrointestinal stromal tumors: evolving role of the multidisciplinary team approach in management. Expert Rev Anticancer Ther 2012 0.79
91 Surgery in soft tissue sarcoma: more conservative in extremities, more extended in the retroperitoneum. Expert Rev Anticancer Ther 2012 0.78
92 Development of transplantable human chordoma xenograft for preclinical assessment of novel therapeutic strategies. Neuro Oncol 2014 0.78
93 Telomere maintenance mechanisms in malignant peripheral nerve sheath tumors: expression and prognostic relevance. Neuro Oncol 2012 0.78
94 MRP1 overexpression determines poor prognosis in prospectively treated patients with localized high-risk soft tissue sarcoma of limbs and trunk wall: an ISG/GEIS study. Mol Cancer Ther 2013 0.78
95 The role of hyperthermic intraperitoneal chemotherapy (HIPEC) and isolated perfusion (ILP) interventions in sarcoma. J Surg Oncol 2014 0.77
96 Imatinib response in two GIST patients carrying two hitherto functionally uncharacterized PDGFRA mutations: an imaging, biochemical and molecular modeling study. Int J Cancer 2011 0.77
97 Personalizing surgical margins in retroperitoneal sarcomas. Expert Rev Anticancer Ther 2015 0.76
98 Efficacy and economic value of adjuvant imatinib for gastrointestinal stromal tumors. Oncologist 2013 0.75
99 Optimal approach to sporadic desmoid tumors: from radical surgery to observation. Time for a consensus? Ann Surg Oncol 2012 0.75
100 ILP and RT: the study that will never be. Ann Surg Oncol 2011 0.75
101 Proteomic detection of a large amount of SCGFα in the stroma of GISTs after imatinib therapy. J Transl Med 2011 0.75
102 Long-term Efficacy of Methotrexate Plus Vinblastine/Vinorelbine in a Large Series of Patients Affected by Desmoid-Type Fibromatosis. Cancer J 2017 0.75
103 Leiomyosarcoma and sarcoma with myogenic differentiation: two different entities or 2 faces of the same disease? Cancer 2012 0.75
104 Cytoreductive surgery in advanced GIST: timing is everything. Ann Surg Oncol 2013 0.75
105 Morbidity of left pancreatectomy when associated with multivisceral resection for abdominal mesenchymal neoplasms. JOP 2011 0.75
106 Axial skeletal osteosarcoma: a 25-year monoinstitutional experience in children and adolescents. Med Oncol 2014 0.75
107 Fluorescence in situ hybridization analysis and immunophenotyping of c-Kit/PDGFRA and Bcl-2 expression in gastrointestinal stromal tumors. Anal Quant Cytol Histol 2010 0.75
108 Neoadjuvant treatment: a novel standard? Curr Opin Oncol 2017 0.75
109 Collaborations between SSO and the Connective Tissue Oncology Society (CTOS) series. Ann Surg Oncol 2015 0.75