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1
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A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information.
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Mol Syst Biol
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2007
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11.03
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2
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Genome-scale models of microbial cells: evaluating the consequences of constraints.
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Nat Rev Microbiol
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2004
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9.61
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3
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Integrating high-throughput and computational data elucidates bacterial networks.
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Nature
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2004
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7.72
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4
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Mast cells are essential intermediaries in regulatory T-cell tolerance.
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Nature
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2006
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5.49
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5
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Towards environmental systems biology of Shewanella.
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Nat Rev Microbiol
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2008
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4.37
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6
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Severe human lower respiratory tract illness caused by respiratory syncytial virus and influenza virus is characterized by the absence of pulmonary cytotoxic lymphocyte responses.
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J Infect Dis
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2007
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3.62
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7
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Hierarchical thinking in network biology: the unbiased modularization of biochemical networks.
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Trends Biochem Sci
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2004
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3.31
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8
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Experimental and computational assessment of conditionally essential genes in Escherichia coli.
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J Bacteriol
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2006
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2.93
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9
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Rapid antigen testing compares favorably with transcription-mediated amplification assay for the detection of Trichomonas vaginalis in young women.
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Clin Infect Dis
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2007
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2.85
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10
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Transcriptional patterns in both host and bacterium underlie a daily rhythm of anatomical and metabolic change in a beneficial symbiosis.
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Proc Natl Acad Sci U S A
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2010
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1.82
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11
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The global transcriptional regulatory network for metabolism in Escherichia coli exhibits few dominant functional states.
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Proc Natl Acad Sci U S A
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2005
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1.63
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12
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A community effort towards a knowledge-base and mathematical model of the human pathogen Salmonella Typhimurium LT2.
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BMC Syst Biol
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2011
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1.50
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13
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Constraint-based model of Shewanella oneidensis MR-1 metabolism: a tool for data analysis and hypothesis generation.
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PLoS Comput Biol
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2010
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1.48
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14
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OptORF: Optimal metabolic and regulatory perturbations for metabolic engineering of microbial strains.
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BMC Syst Biol
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2010
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1.47
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15
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MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function.
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J Allergy Clin Immunol
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2010
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1.41
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16
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The evolution of metabolic networks of E. coli.
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BMC Syst Biol
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2011
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1.32
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17
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Respiratory syncytial virus and influenza virus infections: observations from tissues of fatal infant cases.
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Pediatr Infect Dis J
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2008
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1.31
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18
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Network-based analysis of metabolic regulation in the human red blood cell.
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J Theor Biol
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2003
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1.23
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19
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Analysis of metabolic capabilities using singular value decomposition of extreme pathway matrices.
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Biophys J
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2003
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1.17
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20
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Mycoplasma genitalium detected by transcription-mediated amplification is associated with Chlamydia trachomatis in adolescent women.
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Sex Transm Dis
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2008
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1.17
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21
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Metabolic reconstruction and modeling of nitrogen fixation in Rhizobium etli.
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PLoS Comput Biol
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2007
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1.12
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22
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Isolation and characterization of monoclonal antibodies which neutralize human metapneumovirus in vitro and in vivo.
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J Virol
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2006
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1.09
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23
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Safety and immunogenicity of a recombinant parvovirus B19 vaccine formulated with MF59C.1.
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J Infect Dis
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2003
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1.05
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24
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Genome-scale modeling of light-driven reductant partitioning and carbon fluxes in diazotrophic unicellular cyanobacterium Cyanothece sp. ATCC 51142.
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PLoS Comput Biol
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2012
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1.05
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25
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An automated phenotype-driven approach (GeneForce) for refining metabolic and regulatory models.
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PLoS Comput Biol
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2010
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1.05
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26
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Predicting outcomes of steady-state ¹³C isotope tracing experiments using Monte Carlo sampling.
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BMC Syst Biol
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2012
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1.02
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27
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Complex physiology and compound stress responses during fermentation of alkali-pretreated corn stover hydrolysate by an Escherichia coli ethanologen.
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Appl Environ Microbiol
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2012
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1.00
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28
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Atlantoaxial rotary subluxation after minor trauma.
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Pediatr Emerg Care
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2008
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0.99
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29
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Large-scale bi-level strain design approaches and mixed-integer programming solution techniques.
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PLoS One
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2011
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0.99
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30
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Pyruvate and lactate metabolism by Shewanella oneidensis MR-1 under fermentation, oxygen limitation, and fumarate respiration conditions.
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Appl Environ Microbiol
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2011
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0.98
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31
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Synergy between (13)C-metabolic flux analysis and flux balance analysis for understanding metabolic adaptation to anaerobiosis in E. coli.
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Metab Eng
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2010
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0.98
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32
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RELATCH: relative optimality in metabolic networks explains robust metabolic and regulatory responses to perturbations.
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Genome Biol
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2012
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0.97
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33
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iRsp1095: a genome-scale reconstruction of the Rhodobacter sphaeroides metabolic network.
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BMC Syst Biol
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2011
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0.95
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34
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Identification of functional differences in metabolic networks using comparative genomics and constraint-based models.
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PLoS One
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2012
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0.94
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35
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Computational evaluation of Synechococcus sp. PCC 7002 metabolism for chemical production.
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Biotechnol J
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2013
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0.90
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36
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Improving notification of sexually transmitted infections: a quality improvement project and planned experiment.
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Pediatrics
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2012
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0.89
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37
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Randomized trial of Nordic walking in patients with moderate to severe heart failure.
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Can J Cardiol
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2013
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0.85
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38
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Quantitative assessment of thermodynamic constraints on the solution space of genome-scale metabolic models.
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Biophys J
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2013
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0.85
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39
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Software platforms to facilitate reconstructing genome-scale metabolic networks.
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Environ Microbiol
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2013
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0.85
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40
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Intrapersonal, social and physical environmental determinants of moderate-to-vigorous physical activity in working-age women: a systematic review protocol.
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Syst Rev
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2014
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0.84
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41
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Inferring ancient metabolism using ancestral core metabolic models of enterobacteria.
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BMC Syst Biol
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2013
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0.83
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42
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Cytosolic, autocrine alpha-1 proteinase inhibitor (A1PI) inhibits caspase-1 and blocks IL-1β dependent cytokine release in monocytes.
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PLoS One
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2012
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0.83
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43
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Individual, social and physical environmental correlates of sedentary behaviours in adults: a systematic review protocol.
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Syst Rev
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2014
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0.83
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44
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FOCAL: an experimental design tool for systematizing metabolic discoveries and model development.
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Genome Biol
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2012
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0.82
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45
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Constraint-based strain design using continuous modifications (CosMos) of flux bounds finds new strategies for metabolic engineering.
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Biotechnol J
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2013
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0.82
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46
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Mechanistic analysis of multi-omics datasets to generate kinetic parameters for constraint-based metabolic models.
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BMC Bioinformatics
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2013
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0.82
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47
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Point-of-care testing improves accuracy of STI care in an emergency department.
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Sex Transm Infect
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2013
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0.81
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48
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Epitope mapping by random peptide phage display reveals essential residues for vaccinia extracellular enveloped virion spread.
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Virol J
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2012
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0.81
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49
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Computational approaches in metabolic engineering.
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J Biomed Biotechnol
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2011
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0.80
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50
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BioMog: a computational framework for the de novo generation or modification of essential biomass components.
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PLoS One
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2013
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0.79
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51
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Effect of high dietary restraint on energy availability and menstrual status.
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Med Sci Sports Exerc
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2013
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0.76
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52
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Electronic cigarettes.
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CMAJ
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2013
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0.75
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53
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Correction: Directed Evolution Reveals Unexpected Epistatic Interactions That Alter Metabolic Regulation and Enable Anaerobic Xylose Use by Saccharomyces cerevisiae.
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PLoS Genet
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2016
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0.75
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54
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Mucosal antibody responses are directed by viral burden in children with acute influenza infection.
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Influenza Other Respir Viruses
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2012
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0.75
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55
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Improving flux predictions by integrating data from multiple strains.
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Bioinformatics
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2017
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0.75
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56
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Do Adolescents With Higher Knowledge of HIV Have Lower Sexual Risk Behaviors?
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Pediatr Emerg Care
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2016
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0.75
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