Published in Curr Opin Pharmacol on June 28, 2010
IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma. J Allergy Clin Immunol (2013) 1.14
Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration. Pflugers Arch (2012) 0.88
Lyn mitigates mouse airway remodeling by downregulating the TGF-β3 isoform in house dust mite models. J Immunol (2013) 0.86
Putting the Squeeze on Airway Epithelia. Physiology (Bethesda) (2015) 0.86
The preventive effect of Brassica napus L. oil on pathophysiological changes of respiratory system in experimental asthmatic rat. Avicenna J Phytomed (2013) 0.85
STAT6 controls the number of regulatory T cells in vivo, thereby regulating allergic lung inflammation. J Immunol (2013) 0.85
Central role of cellular senescence in TSLP-induced airway remodeling in asthma. PLoS One (2013) 0.82
Recombinant rat CC10 protein inhibits PDGF-induced airway smooth muscle cells proliferation and migration. Biomed Res Int (2013) 0.82
Long-term evaluation of mesenchymal stem cell therapy in a feline model of chronic allergic asthma. Clin Exp Allergy (2014) 0.81
Role of angiogenic factors in airway remodeling in an allergic rhinitis murine model. Allergy Asthma Immunol Res (2011) 0.81
FIZZ1 promotes airway remodeling through the PI3K/Akt signaling pathway in asthma. Exp Ther Med (2014) 0.80
Cell Jamming in the Airway Epithelium. Ann Am Thorac Soc (2016) 0.80
Pharmacotherapy of patients with mild persistent asthma: strategies and unresolved issues. Front Pharmacol (2011) 0.79
The Chinese Herbal Medicine Formula Sheng-Fei-Yu-Chuan-Tang Suppresses Th2 Responses and Increases IFN γ in Dermatophagoides pteronyssinus Induced Chronic Asthmatic Mice. Evid Based Complement Alternat Med (2013) 0.79
Gpr97 Is Dispensable for Inflammation in OVA-Induced Asthmatic Mice. PLoS One (2015) 0.78
CTGF upregulation correlates with MMP-9 level in airway remodeling in a murine model of asthma. Arch Med Sci (2016) 0.77
Evidences of Herbal Medicine-Derived Natural Products Effects in Inflammatory Lung Diseases. Mediators Inflamm (2016) 0.77
Antimitogenic effect of bitter taste receptor agonists on airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol (2015) 0.77
Apigenin inhibits TGF-β1-induced proliferation and migration of airway smooth muscle cells. Int J Clin Exp Pathol (2015) 0.76
TNF-α-induces airway hyperresponsiveness to cholinergic stimulation in guinea pig airways. Br J Pharmacol (2012) 0.76
A Novel in vivo System to Test Bronchodilators. J Infect Pulm Dis (2017) 0.75
Th-17 regulatory cytokines inhibit corticosteroid induced airway structural cells apoptosis. Respir Res (2016) 0.75
P2Y6 contributes to ovalbumin-induced allergic asthma by enhancing mast cell function in mice. Oncotarget (2016) 0.75
Small airway dysfunction and bronchial asthma control : the state of the art. Asthma Res Pract (2015) 0.75
Potential of Inducible Nitric Oxide Synthase as a Therapeutic Target for Allergen-Induced Airway Hyperresponsiveness: A Critical Connection to Nitric Oxide Levels and PARP Activity. Mediators Inflamm (2016) 0.75
Pathogenetic and prognostic roles of bloodborne fibrocytes in asthma. J Zhejiang Univ Sci B (2015) 0.75
Bitter Taste Receptor Agonists Alter Mitochondrial Function and Induce Autophagy in Airway Smooth Muscle Cells. Am J Physiol Lung Cell Mol Physiol (2017) 0.75
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J (2013) 8.39
Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation. Science (2004) 6.28
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science (2011) 6.19
Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis. J Clin Invest (2003) 4.08
Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I. J Exp Med (2010) 3.98
Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis. J Exp Med (2011) 3.63
IRF8 mutations and human dendritic-cell immunodeficiency. N Engl J Med (2011) 3.29
Airway remodeling-associated mediators in moderate to severe asthma: effect of steroids on TGF-beta, IL-11, IL-17, and type I and type III collagen expression. J Allergy Clin Immunol (2003) 2.98
T(H)17-associated cytokines (IL-17A and IL-17F) in severe asthma. J Allergy Clin Immunol (2009) 2.54
Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis. Immunity (2010) 2.47
B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans. J Exp Med (2010) 2.42
Increased expression of IL-33 in severe asthma: evidence of expression by airway smooth muscle cells. J Immunol (2009) 2.42
Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries. Medicine (Baltimore) (2010) 2.33
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells. Nature (2012) 2.32
Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency. Medicine (Baltimore) (2010) 2.26
Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients. J Allergy Clin Immunol (2012) 2.24
Increased IL-33 expression by epithelial cells in bronchial asthma. J Allergy Clin Immunol (2010) 2.17
Mycobacterial disease and impaired IFN-γ immunity in humans with inherited ISG15 deficiency. Science (2012) 2.06
Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report. J Allergy Clin Immunol (2006) 2.00
Injurious ventilation induces widespread pulmonary epithelial expression of tumor necrosis factor-alpha and interleukin-6 messenger RNA. Crit Care Med (2002) 1.93
Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency. J Clin Invest (2011) 1.88
Outcome of hematopoietic stem cell transplantation for adenosine deaminase-deficient severe combined immunodeficiency. Blood (2012) 1.80
Chlorine-induced injury to the airways in mice. Am J Respir Crit Care Med (2003) 1.79
Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease. Nat Immunol (2011) 1.76
Upper airway muscle inflammation and denervation changes in obstructive sleep apnea. Am J Respir Crit Care Med (2004) 1.75
Role of transforming growth factor-β in airway remodeling in asthma. Am J Respir Cell Mol Biol (2010) 1.71
IL-17 promotes p38 MAPK-dependent endothelial activation enhancing neutrophil recruitment to sites of inflammation. J Immunol (2010) 1.65
Remodeling in asthma. J Allergy Clin Immunol (2011) 1.64
S epsilon S mu and S epsilon S gamma switch circles in human nasal mucosa following ex vivo allergen challenge: evidence for direct as well as sequential class switch recombination. J Immunol (2003) 1.61
Airway remodeling in subjects with severe asthma with or without chronic persistent airflow obstruction. J Allergy Clin Immunol (2009) 1.52
Differences in airway remodeling between subjects with severe and moderate asthma. J Allergy Clin Immunol (2005) 1.52
Improper inhaler technique is associated with poor asthma control and frequent emergency department visits. Allergy Asthma Clin Immunol (2013) 1.51
Vitamin D levels in Saudi children with type 1 diabetes. Saudi Med J (2011) 1.50
Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma. J Allergy Clin Immunol (2005) 1.49
Involvement of the cysteinyl-leukotrienes in allergen-induced airway eosinophilia and hyperresponsiveness in the mouse. Am J Respir Cell Mol Biol (2003) 1.49
Control of airway inflammation maintained at a lower steroid dose with 100/50 microg of fluticasone propionate/salmeterol. J Allergy Clin Immunol (2006) 1.44
Vitamin D deficiency as a strong predictor of asthma in children. Int Arch Allergy Immunol (2011) 1.44
Airway inflammation assessed by invasive and noninvasive means in severe asthma: eosinophilic and noneosinophilic phenotypes. J Allergy Clin Immunol (2006) 1.43
Effect of salmeterol/fluticasone propionate on airway inflammation in COPD: a randomised controlled trial. Thorax (2007) 1.42
Increased expression of ADAM33 and ADAM8 with disease progression in asthma. J Allergy Clin Immunol (2007) 1.40
IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts. J Allergy Clin Immunol (2006) 1.37
Airway remodeling in asthma. Allergol Int (2007) 1.36
Differences in airway cytokine profile in severe asthma compared to moderate asthma. Chest (2007) 1.36
Distribution of nitric oxide synthase in normal and cirrhotic human liver. Proc Natl Acad Sci U S A (2002) 1.33
IL-9 in allergic inflammation. Int Arch Allergy Immunol (2004) 1.27
Myosin, transgelin, and myosin light chain kinase: expression and function in asthma. Am J Respir Crit Care Med (2008) 1.27
LPS-responsive beige-like anchor (LRBA) gene mutation in a family with inflammatory bowel disease and combined immunodeficiency. J Allergy Clin Immunol (2012) 1.26
Anti-IL-5 (mepolizumab) therapy induces bone marrow eosinophil maturational arrest and decreases eosinophil progenitors in the bronchial mucosa of atopic asthmatics. J Allergy Clin Immunol (2003) 1.23
Inherited IL-12p40 deficiency: genetic, immunologic, and clinical features of 49 patients from 30 kindreds. Medicine (Baltimore) (2013) 1.22
Remodeling in asthma. Proc Am Thorac Soc (2009) 1.20
Prevalence of obstructive sleep apnea-hypopnea in severe versus moderate asthma. J Allergy Clin Immunol (2009) 1.18
A calcium-activated chloride channel (HCLCA1) is strongly related to IL-9 expression and mucus production in bronchial epithelium of patients with asthma. J Allergy Clin Immunol (2002) 1.16
Oral corticosteroids decrease eosinophil and CC chemokine expression but increase neutrophil, IL-8, and IFN-gamma-inducible protein 10 expression in asthmatic airway mucosa. J Allergy Clin Immunol (2005) 1.16
Amb a 1-immunostimulatory oligodeoxynucleotide conjugate immunotherapy decreases the nasal inflammatory response. J Allergy Clin Immunol (2004) 1.16
Th17-associated cytokines promote human airway smooth muscle cell proliferation. FASEB J (2012) 1.14
Airway remodelling in asthma: from benchside to clinical practice. Can Respir J (2010) 1.11
A novel form of human STAT1 deficiency impairing early but not late responses to interferons. Blood (2010) 1.11
Airway smooth muscle remodeling is a dynamic process in severe long-standing asthma. J Allergy Clin Immunol (2010) 1.11
Coordinated involvement of mast cells and T cells in allergic mucosal inflammation: critical role of the CC chemokine ligand 1:CCR8 axis. J Immunol (2007) 1.10
Influence of cigarette smoke on the arginine pathway in asthmatic airways: increased expression of arginase I. J Allergy Clin Immunol (2007) 1.10
CCR3 expression and function in asthmatic airway smooth muscle cells. J Immunol (2005) 1.08
IL-9-mediated induction of eotaxin1/CCL11 in human airway smooth muscle cells. J Immunol (2004) 1.07
CD8 positive T cells express IL-17 in patients with chronic obstructive pulmonary disease. Respir Res (2011) 1.07
T helper 17 cells in airway diseases: from laboratory bench to bedside. Chest (2013) 1.06
The immunomodulatory actions of prostaglandin E2 on allergic airway responses in the rat. J Immunol (2002) 1.05
Immunopathology of atopic dermatitis. J Allergy Clin Immunol (2006) 1.05
Evidence of remodeling in peripheral airways of patients with mild to moderate asthma: effect of hydrofluoroalkane-flunisolide. J Allergy Clin Immunol (2005) 1.05
Images in allergy and immunology: neutrophils in asthma. J Allergy Clin Immunol (2007) 1.02
Inhibition of allergic airways inflammation and airway hyperresponsiveness in mice by dexamethasone: role of eosinophils, IL-5, eotaxin, and IL-13. J Allergy Clin Immunol (2003) 1.01
TNF-alpha and IFN-gamma inversely modulate expression of the IL-17E receptor in airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol (2006) 1.01
Effect of HFA-flunisolide on peripheral lung inflammation in asthma. J Allergy Clin Immunol (2003) 1.00
Synthesis of IL-13 by human B lymphocytes: regulation and role in IgE production. J Allergy Clin Immunol (2004) 0.99
Role of toll-like receptor 4 in protection by bacterial lipopolysaccharide in the nasal mucosa of atopic children but not adults. Lancet (2004) 0.99
5-oxo-6,8,11,14-eicosatetraenoic acid induces the infiltration of granulocytes into human skin. J Allergy Clin Immunol (2003) 0.99
TH17 cytokines induce human airway smooth muscle cell migration. J Allergy Clin Immunol (2011) 0.99
Mucin overproduction in chronic inflammatory lung disease. Can Respir J (2006) 0.97
Variability of sputum inflammatory cells in asthmatic patients receiving corticosteroid therapy: A prospective study using multiple samples. J Allergy Clin Immunol (2010) 0.97
ATG5, autophagy and lung function in asthma. Autophagy (2012) 0.96
Marked up-regulation of T lymphocytes and expression of interleukin-9 in bronchial biopsies from patients With chronic bronchitis with obstruction. Chest (2003) 0.96
Cigarette smoke increases TLR4 and TLR9 expression and induces cytokine production from CD8(+) T cells in chronic obstructive pulmonary disease. Respir Res (2011) 0.96
Glucocorticoid receptor-beta up-regulation and steroid resistance induction by IL-17 and IL-23 cytokine stimulation in peripheral mononuclear cells. J Clin Immunol (2012) 0.96
Clinical, immunological and molecular characterization of DOCK8 and DOCK8-like deficient patients: single center experience of twenty-five patients. J Clin Immunol (2012) 0.95
Factors associated with patient visits to the emergency department for asthma therapy. BMC Pulm Med (2012) 0.95
Intrasinus administration of topical budesonide to allergic patients with chronic rhinosinusitis following surgery. Laryngoscope (2002) 0.95
Obstructive sleep apnea syndrome and inflammation. J Allergy Clin Immunol (2005) 0.94
Dominant-negative STAT1 SH2 domain mutations in unrelated patients with Mendelian susceptibility to mycobacterial disease. Hum Mutat (2012) 0.93
Expression of IL-9 receptor alpha chain on human germinal center B cells modulates IgE secretion. J Allergy Clin Immunol (2007) 0.93
Genetic deletion of IL-17A reduces cigarette smoke-induced inflammation and alveolar type II cell apoptosis. Am J Physiol Lung Cell Mol Physiol (2013) 0.92
Human airway smooth muscle cells express the high affinity receptor for IgE (Fc epsilon RI): a critical role of Fc epsilon RI in human airway smooth muscle cell function. J Immunol (2005) 0.92
IL-22 contributes to TGF-β1-mediated epithelial-mesenchymal transition in asthmatic bronchial epithelial cells. Respir Res (2013) 0.92
Involvement of IL-9 in the bronchial phenotype of patients with nasal polyposis. J Allergy Clin Immunol (2004) 0.92
Genetic and histologic evidence for autophagy in asthma pathogenesis. J Allergy Clin Immunol (2011) 0.91
Allergen-induced increases in bone marrow T lymphocytes and interleukin-5 expression in subjects with asthma. Am J Respir Crit Care Med (2002) 0.91
Inflammation and remodeling of the sinus mucosa in children and adults with chronic sinusitis. Laryngoscope (2003) 0.90
Clinical, immunological, and molecular characterization of hyper-IgM syndrome due to CD40 deficiency in eleven patients. J Clin Immunol (2013) 0.90
Role of airway smooth muscle in airway remodeling. J Allergy Clin Immunol (2005) 0.90