Published in J Physiol on May 01, 1991
Pathophysiology of sleep apnea. Physiol Rev (2010) 4.69
Evidence for reflex upper airway dilator muscle activation by sudden negative airway pressure in man. J Physiol (1991) 1.98
Mechanisms of apnea. Prog Cardiovasc Dis (2008) 1.53
Upper airway neuromuscular compensation during sleep is defective in obstructive sleep apnea. J Appl Physiol (1985) (2008) 1.48
The effect of sleep on reflex genioglossus muscle activation by stimuli of negative airway pressure in humans. J Physiol (1994) 1.34
The effect of sleep onset on upper airway muscle activity in patients with sleep apnoea versus controls. J Physiol (2005) 1.31
Postural effects on pharyngeal protective reflex mechanisms. Sleep (2004) 1.30
Sensory regulation of swallowing and airway protection: a role for the internal superior laryngeal nerve in humans. J Physiol (2003) 1.28
Sleep. 2: pathophysiology of obstructive sleep apnoea/hypopnoea syndrome. Thorax (2004) 1.24
Genioglossal muscle response to CO2 stimulation during NREM sleep. Sleep (2006) 1.21
Phasic mechanoreceptor stimuli can induce phasic activation of upper airway muscles in humans. J Physiol (2001) 1.18
Effect of wake-sleep transitions and rapid eye movement sleep on pharyngeal muscle response to negative pressure in humans. J Physiol (1999) 1.14
Genioglossus reflex inhibition to upper-airway negative-pressure stimuli during wakefulness and sleep in healthy males. J Physiol (2007) 1.12
Within-breath control of genioglossal muscle activation in humans: effect of sleep-wake state. J Physiol (2003) 1.11
Sleep-related breathing disorder.2. Pathophysiology of obstructive sleep apnoea. Thorax (1995) 1.08
Control of upper airway muscle activity in younger versus older men during sleep onset. J Physiol (2003) 1.06
Genioglossal inspiratory activation: central respiratory vs mechanoreceptive influences. Respir Physiol (2001) 1.03
Computational simulation of human upper airway collapse using a pressure-/state-dependent model of genioglossal muscle contraction under laminar flow conditions. J Appl Physiol (1985) (2005) 1.02
Recruitment and rate-coding strategies of the human genioglossus muscle. J Appl Physiol (1985) (2010) 1.01
State-dependent and reflex drives to the upper airway: basic physiology with clinical implications. J Appl Physiol (1985) (2013) 0.99
Tonically discharging genioglossus motor units show no evidence of rate coding with hypercapnia. J Neurophysiol (2010) 0.98
Reflex respiratory response to changes in upper airway pressure in the anaesthetized rat. J Physiol (2001) 0.97
Abraham Guz (1929-2014). J Physiol (2014) 0.97
Mechanical properties of the upper airway. Compr Physiol (2012) 0.96
Upper airway collapsibility, dilator muscle activation and resistance in sleep apnoea. Eur Respir J (2007) 0.96
Mechanisms of sleep-disordered breathing: causes and consequences. Pflugers Arch (2011) 0.88
A simple procedure for measuring pharyngeal sensitivity: a contribution to the diagnosis of sleep apnoea. Thorax (2005) 0.87
Obstructive sleep apnea syndrome: natural history, diagnosis, and emerging treatment options. Nat Sci Sleep (2010) 0.87
Upper airway sensory function in children with obstructive sleep apnea syndrome. Sleep (2010) 0.83
Computational fluid dynamics endpoints for assessment of adenotonsillectomy outcome in obese children with obstructive sleep apnea syndrome. J Biomech (2014) 0.83
Influence of pharyngeal muscle activity on inspiratory negative effort dependence in the human upper airway. Respir Physiol Neurobiol (2014) 0.83
A secondary reflex suppression phase is present in genioglossus but not tensor palatini in response to negative upper airway pressure. J Appl Physiol (1985) (2010) 0.82
Effects of CO2 and H+ on laryngeal receptor activity in the perfused larynx in anaesthetized cats. J Physiol (1999) 0.81
Smoking induces oropharyngeal narrowing and increases the severity of obstructive sleep apnea syndrome. J Clin Sleep Med (2012) 0.80
Tailored treatment strategies for obstructive sleep apnea. Respir Investig (2015) 0.78
Neural Control of the Upper Airway: Respiratory and State-Dependent Mechanisms. Compr Physiol (2016) 0.78
Healthy humans with a narrow upper airway maintain patency during quiet breathing by dilating the airway during inspiration. J Physiol (2014) 0.77
Pathophysiology & genetics of obstructive sleep apnoea. Indian J Med Res (2010) 0.77
Effect of route of breathing on the ventilatory and arousal responses to hypercapnia in awake and sleeping dogs. J Physiol (1993) 0.77
Reversal of functional disorders by aspiration, expiration, and cough reflexes and their voluntary counterparts. Front Physiol (2012) 0.77
Inhibition of inspiratory motor output by high-frequency low-pressure oscillations in the upper airway of sleeping dogs. J Physiol (1999) 0.77
Computational fluid dynamics upper airway effective compliance, critical closing pressure, and obstructive sleep apnea severity in obese adolescent girls. J Appl Physiol (1985) (2016) 0.75
Pathogenesis of upper airway occlusion during sleep. J Appl Physiol Respir Environ Exerc Physiol (1978) 5.48
Evidence for reflex upper airway dilator muscle activation by sudden negative airway pressure in man. J Physiol (1991) 1.98
Information arising from the tracheobronchial tree of mammals. Physiol Rev (1982) 1.79
Genioglossus muscle responses to upper airway pressure changes: afferent pathways. J Appl Physiol Respir Environ Exerc Physiol (1982) 1.62
Nasal and laryngeal reflex responses to negative upper airway pressure. J Appl Physiol Respir Environ Exerc Physiol (1984) 1.46
Collapsibility of the human upper airway during normal sleep. J Appl Physiol (1985) (1989) 1.34
Response of genioglossus muscle activity to nasal airway occlusion in normal sleeping adults. J Appl Physiol (1985) (1988) 1.18
Upper airway and respiratory muscle responses to continuous negative airway pressure. J Appl Physiol (1985) (1989) 1.14
Afferent pathways for hypoglossal and phrenic responses to changes in upper airway pressure. Respir Physiol (1984) 1.09
Breathing route influences upper airway muscle activity in awake normal adults. J Appl Physiol (1985) (1989) 1.03
Tongue movements--brainstem mechanisms and clinical postulates. Brain Behav Evol (1984) 0.97
Nasal 'pressure' receptors. Nihon Juigaku Zasshi (1990) 0.91
Protective effect of BCG vaccination in infant Asians: a case-control study. Arch Dis Child (1988) 4.71
Recombinant DNase in cystic fibrosis: a protocol for targeted introduction through n-of-1 trials. Scottish Cystic Fibrosis Group. Eur Respir J (1999) 2.05
Sites and sizes of fat deposits around the pharynx in obese patients with obstructive sleep apnoea and weight matched controls. Eur Respir J (1989) 2.04
Diazepam in the treatment of dyspnoea in the 'Pink Puffer' syndrome. Q J Med (1980) 2.01
Evidence for reflex upper airway dilator muscle activation by sudden negative airway pressure in man. J Physiol (1991) 1.98
Lung clearance index is a sensitive, repeatable and practical measure of airways disease in adults with cystic fibrosis. Thorax (2007) 1.93
Regional cerebral blood flow during volitional breathing in man. J Physiol (1991) 1.84
Inappropriate inhaler use: assessment of use and patient preference of seven inhalation devices. EDICI. Respir Med (2000) 1.80
DNase in cystic fibrosis: the challenge of assessing response and maximising benefit. Thorax (1998) 1.74
Exhaled nitric oxide is not elevated in the inflammatory airways diseases of cystic fibrosis and bronchiectasis. Eur Respir J (1998) 1.72
Lipopolysaccharide, tumor necrosis factor, and interleukin-1 interact to cause hypotension. J Lab Clin Med (1992) 1.65
Observations of renal function in patients undergoing therapeutic diuresis with frusemide. Clin Sci (1970) 1.61
Laboratory assessment of fitness to fly in patients with lung disease: a practical approach. Eur Respir J (2000) 1.60
Motor cortical representation of the diaphragm in man. J Physiol (1991) 1.60
Controlled trial of respiratory health worker visiting patients with chronic respiratory disability. Br Med J (Clin Res Ed) (1987) 1.59
The role of vagal and glossopharyngeal afferent nerves in respiratory sensation, control of breathing and arterial pressure regulation in conscious man. Clin Sci (1966) 1.55
The measurement of breathlessness induced in normal subjects: validity of two scaling techniques. Clin Sci (Lond) (1985) 1.53
Airways in cystic fibrosis are acidified: detection by exhaled breath condensate. Thorax (2002) 1.51
Pharyngeal size and shape during wakefulness and sleep in patients with obstructive sleep apnoea. Q J Med (1989) 1.49
Changes in global cerebral blood flow in humans: effect on regional cerebral blood flow during a neural activation task. J Physiol (1993) 1.48
Carbon monoxide in alveolar air as an index of exposure to cigarette smoke. Clin Sci Mol Med (1976) 1.47
Unilateral focal lesions in the rostrolateral medulla influence chemosensitivity and breathing measured during wakefulness, sleep, and exercise. J Neurol Neurosurg Psychiatry (1999) 1.45
Regional cerebral blood flow during volitional expiration in man: a comparison with volitional inspiration. J Physiol (1993) 1.44
An outbreak of tuberculosis in a children's hospital. J Hosp Infect (1986) 1.42
Synchronization of motor unit firing during different respiratory and postural tasks in human sternocleidomastoid muscle. J Physiol (1989) 1.41
Cigarette smoking among secondary schoolchildren in 1975. Prevalence of respiratory symptoms, knowledge of health hazards, and attitudes to smoking and health. J Epidemiol Community Health (1978) 1.41
Studies of the pulmonary vagal control of central respiratory rhythm in the absence of breathing movements. J Physiol (1973) 1.40
Stroke volume in conscious dogs; effect of respiration, posture, and vascular occlusion. J Appl Physiol (1965) 1.40
The effect of anaesthesia of the airway in dog and man: a study of respiratory reflexes, sensations and lung mechanics. Clin Sci Mol Med (1976) 1.36
A self paced treadmill walking test for breathless patients. Thorax (1985) 1.36
Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Gene Ther (1997) 1.36
Extracellular elastolytic activity in human lung lavage: a comparative study between smokers and non-smokers. Clin Sci (Lond) (1985) 1.35
The effect of sleep on reflex genioglossus muscle activation by stimuli of negative airway pressure in humans. J Physiol (1994) 1.34
Nitrite levels in breath condensate of patients with cystic fibrosis is elevated in contrast to exhaled nitric oxide. Thorax (1998) 1.34
Sympathetic and parasympathetic cardiac control in athletes and nonathletes at rest. J Appl Physiol Respir Environ Exerc Physiol (1982) 1.32
Arterial oxygen saturation and breathlessness in patients with chronic obstructive airways disease. Clin Sci (Lond) (1987) 1.32
Is the voluntary control of exercise in man necessary for the ventilatory response? J Physiol (1984) 1.32
The role of non-myelinated vagal afferent fibres from the lungs in the genesis of tachypnoea in the rabbit. J Physiol (1971) 1.31
Cryosurgery in the treatment of head and neck neoplasia. Br J Surg (1972) 1.30
Breathlessness and psychiatric morbidity in chronic bronchitis and emphysema: a study of psychotherapeutic management. Psychol Med (1983) 1.28
The effect of varying tidal volume on the associated phrenic motoneurone output:studies of vagal and chemical feedback. Respir Physiol (1975) 1.28
The effect of airway anaesthesia on the control of breathing and the sensation of breathlessness in man. Clin Sci (Lond) (1985) 1.27
Consensus statement on diagnosis, investigation, treatment and prevention of acute bacterial meningitis in immunocompetent adults. British Infection Society Working Party. J Infect (1999) 1.27
Inspiratory coactivation of the genioglossus enlarges retroglossal space in laryngectomized humans. J Appl Physiol (1985) (1996) 1.26
The effect of bilateral block of vagus and glossopharyngeal nerves on the ventilatory response to CO2 of conscious man. Respir Physiol (1966) 1.26
The role of spinal cord transmission in the ventilatory response to exercise in man. J Physiol (1984) 1.24
Putative cerebral cortical involvement in the ventilatory response to inhaled CO2 in conscious man. J Physiol (1990) 1.23
Validation of beat by beat pulsed Doppler measurements of ascending aortic blood velocity in man. Cardiovasc Res (1987) 1.23
Hyperpnoea during and immediately after exercise in man: evidence of motor cortical involvement. J Physiol (1995) 1.23
Search for evidence of lung chemoreflexes in man: study of respiratory and circulatory effects of phenyldiguanide and lobeline. Clin Sci (1972) 1.22
The effect of carbon dioxide in the airways and alveoli on ventilation; a vagal reflex studied in the dog. J Physiol (1974) 1.22
Blood pressure and flow in the ascending aorta of conscious dogs. Cardiovasc Res (1967) 1.22
Arterial oxygen desaturation during treadmill and bicycle exercise in patients with chronic obstructive airways disease. Clin Sci (Lond) (1985) 1.22
Identification of higher brain centres that may encode the cardiorespiratory response to exercise in humans. J Physiol (2001) 1.21
The language of breathlessness. Use of verbal descriptors by patients with cardiopulmonary disease. Am Rev Respir Dis (1991) 1.21
Mast cells in the human alveolar wall: an electronmicroscopic study. J Clin Pathol (1981) 1.16
Non-islet cell tumour-associated hypoglycaemia: 111In-octreotide imaging and efficacy of octreotide, growth hormone and glucocorticosteroids. Clin Endocrinol (Oxf) (1996) 1.16
Serum carbonic acid pK'1 abnormalities in patients with acid-base disturbances. Clin Sci (1967) 1.14
Detection of lipocortin 1 in human lung lavage fluid: lipocortin degradation as a possible proteolytic mechanism in the control of inflammatory mediators and inflammation. Environ Health Perspect (1990) 1.14
Cerebral areas associated with motor control of speech in humans. J Appl Physiol (1985) (1997) 1.14
The role of spinal cord transmission in the ventilatory response to electrically induced exercise in the anaesthetized dog. J Physiol (1982) 1.14
Abdominal pain in diabetic metabolic decompensation. Clinical significance. JAMA (1975) 1.13
The use of digitalis glycosides in sinus rhythm. Clin Sci Mol Med (1978) 1.13
The role of histamine receptors in asthma. Clin Sci (Lond) (1981) 1.13
Role of pulmonary vagal afferent nerve fibres in the development of rapid shallow breathing in lung inflammation. Clin Sci (1972) 1.12
Sputum and serum calprotectin are useful biomarkers during CF exacerbation. J Cyst Fibros (2010) 1.12
Breathlessness during different forms of ventilatory stimulation: a study of mechanisms in normal subjects and respiratory patients. Clin Sci (Lond) (1985) 1.12
The influence of induced hypocapnia and sleep on the endogenous respiratory rhythm in humans. J Physiol (1991) 1.12
The measurement of breathlessness induced in normal subjects: individual differences. Clin Sci (Lond) (1986) 1.11
Evidence for limbic system activation during CO2-stimulated breathing in man. J Physiol (1995) 1.11
Small bowel tonometry: assessment of small gut mucosal oxygen tension in dog and man. Nature (1965) 1.10
Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung. Gene Ther (2011) 1.10
Cigarette smoking among secondary schoolchildren 1975-79. Arch Dis Child (1982) 1.09
Left ventricular performance in the conscious dog with chronically denervated heart. Cardiovasc Res (1972) 1.08
Antibiotic resistance in common acute respiratory pathogens. Thorax (1995) 1.07
Human cerebral activity with increasing inspiratory force: a study using positron emission tomography. J Appl Physiol (1985) (1996) 1.07
Blockade of 'alveolar' and airway reflexes by local anesthetic aerosol in dogs. Respir Physiol (1987) 1.07
The clinical value of digoxin in patients with heart failure and sinus rhythm. Q J Med (1978) 1.06
Respiratory and cardiovascular effects of central and peripheral intravenous injections of capsaicin in man: evidence for pulmonary chemosensitivity. Clin Sci (Lond) (1986) 1.06
Gastro-intestinal haemorrhage following ingestion of 'Alka-Seltzer'. Scott Med J (1980) 1.06
Respiratory impairment induced by smoking in children in secondary schools. Br Med J (Clin Res Ed) (1984) 1.06
Within-breath modulation of left ventricular function during normal breathing and positive-pressure ventilation in man. J Physiol (1993) 1.06
Excursion-volume relation of the right hemidiaphragm measured by ultrasonography and respiratory airflow measurements. Thorax (1994) 1.05
Effect of changes in heart rat on left ventricular performance in conscious dogs. Circ Res (1969) 1.05
Possible role of drug malabsorption in recrudescence of falciparum malaria. Lancet (1982) 1.04
Does oxygen help dyspnea in patients with cancer? Am J Respir Crit Care Med (1996) 1.03
Cardiac output, oxygen consumption and arteriovenous oxygen difference following a sudden rise in exercise level in humans. J Physiol (1991) 1.02
Non-respiratory tuberculosis. J R Coll Physicians Lond (1981) 1.02
Central command influences cardiorespiratory response to dynamic exercise in humans with unilateral weakness. J Physiol (1992) 1.02
Diaphragmatic movement in hemiplegic patients measured by ultrasonography. Thorax (1994) 1.01
Respiratory modulation of left ventricular stroke volume in man measured using pulsed Doppler ultrasound. J Physiol (1987) 1.01
The early circulatory and ventilatory response to voluntary and electrically induced exercise in man. J Physiol (1987) 1.00
Respiratory sensations in subjects who lack a ventilatory response to CO2. Respir Physiol (1993) 1.00
Cardiopulmonary response to dynamic exercise after heart and combined heart-lung transplantation. Br Heart J (1989) 1.00