Protamine 1 to protamine 2 ratio correlates with dynamic aspects of DNA fragmentation in human sperm.

PubWeight™: 0.87‹?›

🔗 View Article (PMID 20667534)

Published in Fertil Steril on July 29, 2010

Authors

Agustín García-Peiró1, Juan Martínez-Heredia, María Oliver-Bonet, Carlos Abad, María José Amengual, Joaquima Navarro, Celine Jones, Kevin Coward, Jaime Gosálvez, Jordi Benet

Author Affiliations

1: Departament de Biologia Cellular, Fisiologia i Immunologia, Càtedra de Recerca Eugin-UAB, Universitat Autònoma de Barcelona, Bellaterra, Spain. agusti.garcia@uab.es

Articles by these authors

Simple determination of human sperm DNA fragmentation with an improved sperm chromatin dispersion test. Fertil Steril (2005) 3.37

Human sperm devoid of PLC, zeta 1 fail to induce Ca(2+) release and are unable to initiate the first step of embryo development. J Clin Invest (2008) 1.64

Increased pregnancy after reduced male abstinence. Syst Biol Reprod Med (2013) 1.43

Diagnostic accuracy of sperm DNA degradation index (DDSi) as a potential noninvasive biomarker to identify men with varicocele-associated infertility. Int Urol Nephrol (2015) 1.30

A translational medicine appraisal of specialized andrology testing in unexplained male infertility. Int Urol Nephrol (2014) 1.30

Specialized sperm function tests in varicocele and the future of andrology laboratory. Asian J Androl (2016) 1.28

Epigenetics and its role in male infertility. J Assist Reprod Genet (2012) 1.27

Human male recombination maps for individual chromosomes. Am J Hum Genet (2004) 1.21

DNA fragmentation in microorganisms assessed in situ. Appl Environ Microbiol (2008) 1.09

Endothelial cell chimerism does not influence allograft tolerance in liver transplant patients after withdrawal of immunosuppression. Transplantation (2003) 1.08

Types, causes, detection and repair of DNA fragmentation in animal and human sperm cells. Int J Mol Sci (2012) 1.04

Sperm DNA fragmentation in infertile men with genitourinary infection by Chlamydia trachomatis and Mycoplasma. Fertil Steril (2007) 1.03

Application of FISH to detect DNA damage. DNA breakage detection-FISH (DBD-FISH). Methods Mol Biol (2002) 1.00

Marked correlations in protein expression identified by proteomic analysis of human spermatozoa. Proteomics (2007) 0.99

Viability assessment for artificial gametes: the need for biomarkers of functional competency. Biol Reprod (2012) 0.98

A maternally inherited autosomal point mutation in human phospholipase C zeta (PLCζ) leads to male infertility. Hum Reprod (2011) 0.97

Comprehensive embryo analysis of advanced maternal age-related aneuploidies and mosaicism by short comparative genomic hybridization. Fertil Steril (2010) 0.97

DNA fragmentation and meiotic segregation in sperm of carriers of a chromosomal structural abnormality. Fertil Steril (2008) 0.96

The solution structure of the invasive tip complex from Afa/Dr fibrils. Mol Microbiol (2006) 0.95

Alkali-labile sites in sperm cells from Sus and Ovis species. Int J Androl (2007) 0.94

Loss of activity mutations in phospholipase C zeta (PLCζ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytes. Hum Reprod (2011) 0.94

A two-tailed Comet assay for assessing DNA damage in spermatozoa. Reprod Biomed Online (2009) 0.93

Phospholipase C zeta undergoes dynamic changes in its pattern of localization in sperm during capacitation and the acrosome reaction. Fertil Steril (2008) 0.92

Variance in total levels of phospholipase C zeta (PLC-ζ) in human sperm may limit the applicability of quantitative immunofluorescent analysis as a diagnostic indicator of oocyte activation capability. Fertil Steril (2012) 0.92

Double stranded sperm DNA breaks, measured by Comet assay, are associated with unexplained recurrent miscarriage in couples without a female factor. PLoS One (2012) 0.91

Reliability of comparative genomic hybridization to detect chromosome abnormalities in first polar bodies and metaphase II oocytes. Hum Reprod (2004) 0.90

Synapsis and meiotic recombination analyses: MLH1 focus in the XY pair as an indicator. Hum Reprod (2005) 0.90

Birth of a healthy boy after a double factor PGD in a couple carrying a genetic disease and at risk for aneuploidy: case report. Hum Reprod (2008) 0.89

Effects of gonadotrophin releasing hormone analogues on human endometrial stromal cells and embryo invasion in vitro. Hum Reprod (2009) 0.87

Detection of unbalanced chromosome segregations in preimplantation genetic diagnosis of translocations by short comparative genomic hibridization. Fertil Steril (2011) 0.87

Phospholipase C zeta (PLCζ): oocyte activation and clinical links to male factor infertility. Adv Biol Regul (2013) 0.86

Increased aneuploidy rate in sperm with fragmented DNA as determined by the sperm chromatin dispersion (SCD) test and FISH analysis. J Androl (2006) 0.86

Swim-up procedure selects spermatozoa with longer telomere length. Mutat Res (2010) 0.85

New application of the comet assay: chromosome--comet assay. J Histochem Cytochem (2011) 0.85

Rapid and simple determination of ciprofloxacin resistance in clinical strains of Escherichia coli. J Clin Microbiol (2009) 0.85

Motile sperm organelle morphology evaluation-selected globozoospermic human sperm with an acrosomal bud exhibits novel patterns and higher levels of phospholipase C zeta. Hum Reprod (2012) 0.85

Nerve fibers in lumbar spine structures and injured spinal roots express the sensory neuron-specific sodium channels SNS/PN3 and NaN/SNS2. Spine (Phila Pa 1976) (2002) 0.85

Critically short telomeres are associated with sperm DNA fragmentation. Fertil Steril (2005) 0.84

Proteomics in the study of the sperm cell composition, differentiation and function. Syst Biol Reprod Med (2008) 0.84

In vivo gene transfer by electroporation allows expression of a fluorescent transgene in hamster testis and epididymal sperm and has no adverse effects upon testicular integrity or sperm quality. Biol Reprod (2005) 0.84

The importance of aneuploidy screening in reciprocal translocation carriers. Reproduction (2006) 0.84

Multiple mutation analysis of the cystic fibrosis gene in single cells. Mol Hum Reprod (2005) 0.84

The ability of sperm selection techniques to remove single- or double-strand DNA damage. Asian J Androl (2011) 0.83

Infertile men with varicocele show a high relative proportion of sperm cells with intense nuclear damage level, evidenced by the sperm chromatin dispersion test. J Androl (2006) 0.83

Prevalence of bronchiectasis in asthma according to oral steroid requirement: influence of immunoglobulin levels. Biomed Res Int (2013) 0.83

Analysis of invdupdel(8p) rearrangement: Clinical, cytogenetic and molecular characterization. Am J Med Genet A (2015) 0.82

Errors at mitotic segregation early in oogenesis and at first meiotic division in oocytes from donor females: comparative genomic hybridization analyses in metaphase II oocytes and their first polar body. Fertil Steril (2009) 0.82

Oocyte activation and phospholipase C zeta (PLCζ): diagnostic and therapeutic implications for assisted reproductive technology. Cell Commun Signal (2012) 0.82

Comparative biology of sperm factors and fertilization-induced calcium signals across the animal kingdom. Mol Reprod Dev (2013) 0.82

DNA fragmentation dynamics allows the assessment of cryptic sperm damage in human: evaluation of exposure to ionizing radiation, hyperthermia, acidic pH and nitric oxide. Mutat Res (2012) 0.82

DNA damage in women with cervical neoplasia evaluated by DNA breakage detection-fluorescence in situ hybridization. Anal Quant Cytol Histol (2011) 0.82

Interstitial telomeric sequence blocks in constitutive pericentromeric heterochromatin from Pyrgomorpha conica (Orthoptera) are enriched in constitutive alkali-labile sites. Mutat Res (2006) 0.82

An improved experimental model for understanding the impact of sperm DNA fragmentation on human pregnancy following ICSI. Reprod Sci (2012) 0.81

Simultaneous determination in situ of DNA fragmentation and 8-oxoguanine in human sperm. Fertil Steril (2009) 0.81

Karyotyping of human synaptonemal complexes by cenM-FISH. Eur J Hum Genet (2003) 0.81

A rapid in situ procedure for determination of bacterial susceptibility or resistance to antibiotics that inhibit peptidoglycan biosynthesis. BMC Microbiol (2011) 0.81

Characterization of two heterozygous mutations of the oocyte activation factor phospholipase C zeta (PLCζ) from an infertile man by use of minisequencing of individual sperm and expression in somatic cells. Fertil Steril (2012) 0.81

Structure of human sperm DNA and background damage, analysed by in situ enzymatic treatment and digital image analysis. Mol Hum Reprod (2004) 0.81

Reduced fertilization after ICSI and abnormal phospholipase C zeta presence in spermatozoa from the wobbler mouse. Reprod Biomed Online (2010) 0.80

Aberrant protamine content in sperm and consequential implications for infertility treatment. Hum Fertil (Camb) (2014) 0.80

Halosperm is an easy, available, and cost-effective alternative for determining sperm DNA fragmentation. Fertil Steril (2005) 0.80

Whole-comparative genomic hybridization (W-CGH): 1. The quick overview of repetitive DNA sequences on a genome. Chromosome Res (2003) 0.80

Differential resistance of mammalian sperm chromatin to oxidative stress as assessed by a two-tailed comet assay. Reprod Fertil Dev (2011) 0.80

Assessing sperm DNA fragmentation with the sperm chromatin dispersion test. Methods Mol Biol (2011) 0.80

A new method to analyze boar sperm DNA fragmentation under bright-field or fluorescence microscopy. Theriogenology (2005) 0.79

Differential clustering of sperm subpopulations in infertile males with clinical varicocele and carriers of rearranged genomes. J Androl (2011) 0.78

Elevated dietary intake of Zn-methionate is associated with increased sperm DNA fragmentation in the boar. Reprod Toxicol (2010) 0.78

Effects of cryopreservation and density-gradient washing on phospholipase C zeta concentrations in human spermatozoa. Reprod Biomed Online (2011) 0.78

Rapid rates of sperm DNA damage after activation in tench (Tinca tinca: Teleostei, Cyprinidae) measured using a sperm chromatin dispersion test. Reproduction (2009) 0.78

Outcome of twin babies free of Von Hippel-Lindau disease after a double-factor preimplantation genetic diagnosis: monogenetic mutation analysis and comprehensive aneuploidy screening. Fertil Steril (2009) 0.78

Decreased length of telomeric DNA sequences and increased numerical chromosome aberrations in human osteoarthritic chondrocytes. Mutat Res (2011) 0.78