Published in J Vis Exp on July 23, 2010
FOXP3 orchestrates H4K16 acetylation and H3K4 trimethylation for activation of multiple genes by recruiting MOF and causing displacement of PLU-1. Mol Cell (2011) 1.14
A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of Ferrochelatase. Biochemistry (2016) 0.81
Protein kinase CK2 inactivates PRH/Hhex using multiple mechanisms to de-repress VEGF-signalling genes and promote cell survival. Nucleic Acids Res (2012) 0.81
A clickable psoralen to directly quantify DNA interstrand crosslinking and repair. Bioorg Med Chem (2016) 0.75
The cellular DNA helicase ChlR1 regulates chromatin and nuclear matrix attachment of the human papillomavirus type 16 E2 protein and high copy viral genome establishment. J Virol (2016) 0.75
Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery. Epigenetics Chromatin (2015) 0.75
Redistribution and differential extraction of soluble proteins in permeabilized cultured cells. Implications for immunofluorescence microscopy. J Cell Sci (1992) 2.09
Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF(alpha)/AML/PEBP2(alpha)) dependent activation of tissue-specific gene transcription. J Cell Sci (2000) 2.08
Association with the nuclear matrix and interaction with Groucho and RUNX proteins regulate the transcription repression activity of the basic helix loop helix factor Hes1. J Biol Chem (2001) 1.38
The hinge of the human papillomavirus type 11 E2 protein contains major determinants for nuclear localization and nuclear matrix association. J Virol (2000) 1.37
Targeting of the YY1 transcription factor to the nucleolus and the nuclear matrix in situ: the C-terminus is a principal determinant for nuclear trafficking. J Cell Biochem (1998) 1.19
TopBP1 regulates human papillomavirus type 16 E2 interaction with chromatin. J Virol (2007) 1.06
Measuring the induction or inhibition of apoptosis by HPV proteins. Methods Mol Med (2005) 0.88
The transcription factor encyclopedia. Genome Biol (2012) 1.28
The proline-rich homeodomain protein recruits members of the Groucho/Transducin-like enhancer of split protein family to co-repress transcription in hematopoietic cells. J Biol Chem (2004) 1.28
PRH/Hhex controls cell survival through coordinate transcriptional regulation of vascular endothelial growth factor signaling. Mol Cell Biol (2010) 1.14
PRH/Hex: an oligomeric transcription factor and multifunctional regulator of cell fate. Biochem J (2008) 1.11
Urban domestic gardens: the effects of human interventions on garden composition. Environ Manage (2011) 1.10
CK2 phosphorylation of the PRH/Hex homeodomain functions as a reversible switch for DNA binding. Nucleic Acids Res (2009) 1.07
E2 proteins from high- and low-risk human papillomavirus types differ in their ability to bind p53 and induce apoptotic cell death. J Virol (2006) 1.03
Comprehensive comparison of the interaction of the E2 master regulator with its cognate target DNA sites in 73 human papillomavirus types by sequence statistics. Nucleic Acids Res (2007) 0.96
Characterization of an enhancer region of the galanin gene that directs expression to the dorsal root ganglion and confers responsiveness to axotomy. J Neurosci (2007) 0.95
Oligomerisation of the developmental regulator proline rich homeodomain (PRH/Hex) is mediated by a novel proline-rich dimerisation domain. J Mol Biol (2006) 0.93
The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors. Biochem J (2009) 0.92
Comparison of the structure and DNA-binding properties of the E2 proteins from an oncogenic and a non-oncogenic human papillomavirus. J Mol Biol (2003) 0.91
The transcriptional repressor protein PRH interacts with the proteasome. Biochem J (2003) 0.89
DNA wrapping and distortion by an oligomeric homeodomain protein. J Mol Biol (2008) 0.89
The papillomavirus E2 DNA binding domain. Front Biosci (2008) 0.88
Measuring the induction or inhibition of apoptosis by HPV proteins. Methods Mol Med (2005) 0.88
Human papillomavirus type 16 E2- and L1-specific serological and T-cell responses in women with vulval intraepithelial neoplasia. J Gen Virol (2003) 0.86
The recognition of local DNA conformation by the human papillomavirus type 6 E2 protein. Nucleic Acids Res (2006) 0.85
Activation of proteinase-activated receptor 2 stimulates soluble vascular endothelial growth factor receptor 1 release via epidermal growth factor receptor transactivation in endothelial cells. Hypertension (2010) 0.85
P53 represses human papillomavirus type 16 DNA replication via the viral E2 protein. Virol J (2008) 0.84
Protein flexibility directs DNA recognition by the papillomavirus E2 proteins. Nucleic Acids Res (2010) 0.84
Purification of the proline-rich homeodomain protein. J Chromatogr B Analyt Technol Biomed Life Sci (2003) 0.82
Protein kinase CK2 inactivates PRH/Hhex using multiple mechanisms to de-repress VEGF-signalling genes and promote cell survival. Nucleic Acids Res (2012) 0.81
DNA compaction by the higher-order assembly of PRH/Hex homeodomain protein oligomers. Nucleic Acids Res (2010) 0.81
Dasatinib inhibits leukaemic cell survival by decreasing PRH/Hhex phosphorylation resulting in increased repression of VEGF signalling genes. Leuk Res (2012) 0.81
Herpes simplex virus VP22-human papillomavirus E2 fusion proteins produced in mammalian or bacterial cells enter mammalian cells and induce apoptotic cell death. Biotechnol Appl Biochem (2004) 0.81
Purification and characterisation of the PRH homeodomain: Removal of the N-terminal domain of PRH increases the PRH homeodomain-DNA interaction. Int J Biol Macromol (2006) 0.81
The human papillomavirus E7-E2 interaction mechanism in vitro reveals a finely tuned system for modulating available E7 and E2 proteins. Biochemistry (2009) 0.81
A cancer cell-specific inducer of apoptosis. Hum Gene Ther (2007) 0.79
Diffusible VP22-E2 protein kills bystander cells and offers a route for cervical cancer gene therapy. Hum Gene Ther (2006) 0.78
The proline rich homeodomain protein PRH/Hhex forms stable oligomers that are highly resistant to denaturation. PLoS One (2012) 0.77
Development of a topical protein therapeutic for human papillomavirus and associated cancers. BioDrugs (2006) 0.76
A quadrivalent vaccine for human papillomavirus. Drugs Today (Barc) (2006) 0.75