Published in Discov Med on December 01, 2003
Imaging cerebral 2-ketoisocaproate metabolism with hyperpolarized (13)C magnetic resonance spectroscopic imaging. J Cereb Blood Flow Metab (2012) 0.89
Novel Approaches to Imaging Tumor Metabolism. Cancer J (2015) 0.80
Imaging Tumor Metabolism to Assess Disease Progression and Treatment Response. Clin Cancer Res (2016) 0.75
Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR. Proc Natl Acad Sci U S A (2003) 15.81
Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy. Nat Med (2007) 6.84
Real-time metabolic imaging. Proc Natl Acad Sci U S A (2006) 5.89
Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate. Nature (2008) 5.60
13C-angiography. Acad Radiol (2002) 3.24
Overhauser enhanced magnetic resonance imaging for tumor oximetry: coregistration of tumor anatomy and tissue oxygen concentration. Proc Natl Acad Sci U S A (2002) 2.62
Diffusion MRI for prediction of response of rectal cancer to chemoradiation. Lancet (2002) 2.38
13C imaging-a new diagnostic platform. Eur Radiol (2005) 2.04
Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors. Proc Natl Acad Sci U S A (2009) 2.04
Hyperpolarized Xe MR imaging of alveolar gas uptake in humans. PLoS One (2010) 1.73
Quantitative measurement of regional lung ventilation using 3He MRI. Magn Reson Med (2002) 1.47
Diffusion-weighted hyperpolarized 129Xe MRI in healthy volunteers and subjects with chronic obstructive pulmonary disease. Magn Reson Med (2010) 1.46
Direct visualisation of collateral ventilation in COPD with hyperpolarised gas MRI. Thorax (2012) 1.42
Characterization of diffusing capacity and perfusion of the rat lung in a lipopolysaccaride disease model using hyperpolarized 129Xe. Magn Reson Med (2003) 1.32
MR coronary angiography in pigs with intraarterial injections of a hyperpolarized 13C substance. Magn Reson Med (2006) 1.21
Imaging of branched chain amino acid metabolism in tumors with hyperpolarized 13C ketoisocaproate. Int J Cancer (2010) 1.16
Chronic obstructive pulmonary disease: safety and tolerability of hyperpolarized 129Xe MR imaging in healthy volunteers and patients. Radiology (2011) 1.07
Detection of tumor glutamate metabolism in vivo using (13)C magnetic resonance spectroscopy and hyperpolarized [1-(13)C]glutamate. Magn Reson Med (2011) 1.06
Tissue-specific short chain fatty acid metabolism and slow metabolic recovery after ischemia from hyperpolarized NMR in vivo. J Biol Chem (2009) 1.06
Quantitative analysis of hyperpolarized 129Xe ventilation imaging in healthy volunteers and subjects with chronic obstructive pulmonary disease. NMR Biomed (2012) 1.00
Deuteration of a molecular probe for DNP hyperpolarization--a new approach and validation for choline chloride. Contrast Media Mol Imaging (2011) 0.98
[¹⁸F]GE-180: a novel fluorine-18 labelled PET tracer for imaging Translocator protein 18 kDa (TSPO). Bioorg Med Chem Lett (2011) 0.97
Hyperpolarized 13C MRI of the pulmonary vasculature and parenchyma. Magn Reson Med (2007) 0.95
Are gadolinium-based contrast media really safer than iodinated media for digital subtraction angiography in patients with azotemia? Radiology (2002) 0.94
Metabolic pathway visualization in living yeast by DNP-NMR. Mol Biosyst (2011) 0.92
Non-invasive in-cell determination of free cytosolic [NAD+]/[NADH] ratios using hyperpolarized glucose show large variations in metabolic phenotypes. J Biol Chem (2013) 0.92
Passive catheter tracking during interventional MRI using hyperpolarized 13C. Magn Reson Med (2007) 0.88
Hyperpolarized amino acids for in vivo assays of transaminase activity. Chemistry (2009) 0.88
Hyperpolarized [1,3-13C2 ]ethyl acetoacetate is a novel diagnostic metabolic marker of liver cancer. Int J Cancer (2014) 0.87
A hyperpolarized choline molecular probe for monitoring acetylcholine synthesis. Contrast Media Mol Imaging (2010) 0.85
Gadolinium contrast media are more nephrotoxic than iodine media. The importance of osmolality in direct renal artery injections. Eur Radiol (2006) 0.82
3He MRI-based assessment of posture-dependent regional ventilation gradients in rats. J Appl Physiol (1985) (2005) 0.81
High-field dissolution dynamic nuclear polarization of [1-(13)C]pyruvic acid. Phys Chem Chem Phys (2016) 0.81
Experimental validation of the hyperpolarized (129) Xe chemical shift saturation recovery technique in healthy volunteers and subjects with interstitial lung disease. Magn Reson Med (2014) 0.81
Applications of hyperpolarized agents in solutions. Methods Mol Biol (2011) 0.80
Orally administered manganese with and without ascorbic acid as a liver-specific contrast agent and bowel marker for magnetic resonance imaging: phase I clinical trial assessing efficacy and safety. Invest Radiol (2010) 0.79
A study of the use of Overhauser enhancement to assist with needle and catheter placement during interventional MRI. J Magn Reson (2002) 0.79
Relationship between structural changes and hyperpolarized gas magnetic resonance imaging in chronic obstructive pulmonary disease using computational simulations with realistic alveolar geometry. Philos Trans A Math Phys Eng Sci (2009) 0.79
Detection of low-populated reaction intermediates with hyperpolarized NMR. Chem Commun (Camb) (2009) 0.79
Validation of an electronic image reader training programme for interpretation of [18F]flutemetamol β-amyloid PET brain images. Nucl Med Commun (2016) 0.79
Iodixanol 320 results in better renal tolerance and radiodensity than do gadolinium-based contrast media: arteriography in ischemic porcine kidneys. Radiology (2008) 0.78
The rabbit renal toxicity test: a sensitive in vivo test for the nephrotoxicity of contrast agents. Acad Radiol (2002) 0.76
GE-145, a new low-osmolar dimeric radiographic contrast medium. Acta Radiol (2010) 0.76
Regarding "Safety of gadolinium contrast angiography in patients with chronic renal insufficiency". J Vasc Surg (2004) 0.75
Real-time DNP NMR observations of acetic acid uptake, intracellular acidification, and of consequences for glycolysis and alcoholic fermentation in yeast. Chemistry (2013) 0.75
Hyperpolarized molecules in solution. Methods Mol Biol (2011) 0.75
Gadolinium contrast media for DSA in azotemia: are they really safer than iodinated agents? Acad Radiol (2002) 0.75