Graeme L Conn

Author PubWeight™ 24.02‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Distinct contributions of T1R2 and T1R3 taste receptor subunits to the detection of sweet stimuli. Curr Biol 2005 2.00
2 General plasmids for producing RNA in vitro transcripts with homogeneous ends. Nucleic Acids Res 2003 1.56
3 Determination of the target nucleosides for members of two families of 16S rRNA methyltransferases that confer resistance to partially overlapping groups of aminoglycoside antibiotics. Nucleic Acids Res 2009 1.10
4 Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA. Proc Natl Acad Sci U S A 2014 1.06
5 Conserved nucleotides within the J domain of the encephalomyocarditis virus internal ribosome entry site are required for activity and for interaction with eIF4G. J Virol 2003 1.03
6 Systematic deletion of the adenovirus-associated RNAI terminal stem reveals a surprisingly active RNA inhibitor of double-stranded RNA-activated protein kinase. J Biol Chem 2008 1.00
7 Critical residues for cofactor binding and catalytic activity in the aminoglycoside resistance methyltransferase Sgm. J Bacteriol 2008 0.99
8 The solution structure of a DNA*RNA duplex containing 5-propynyl U and C; comparison with 5-Me modifications. Nucleic Acids Res 2003 0.99
9 Structure of the thiostrepton resistance methyltransferase.S-adenosyl-L-methionine complex and its interaction with ribosomal RNA. J Biol Chem 2009 0.96
10 Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria. Nucleic Acids Res 2010 0.95
11 Expression and purification of functional ligand-binding domains of T1R3 taste receptors. Chem Senses 2006 0.95
12 Expression, purification and crystallization of adenosine 1408 aminoglycoside-resistance rRNA methyltransferases for structural studies. Protein Expr Purif 2010 0.94
13 Analysis of adenovirus VA RNAI structure and stability using compensatory base pair modifications. Nucleic Acids Res 2008 0.89
14 Magnesium-dependent interaction of PKR with adenovirus VAI. J Mol Biol 2010 0.89
15 The PKR-binding domain of adenovirus VA RNAI exists as a mixture of two functionally non-equivalent structures. Nucleic Acids Res 2009 0.86
16 Raman and Raman optical activity (ROA) analysis of RNA structural motifs in Domain I of the EMCV IRES. Nucleic Acids Res 2007 0.85
17 Cis-acting ribozymes for the production of RNA in vitro transcripts with defined 5' and 3' ends. Methods Mol Biol 2012 0.84
18 Optimization of a ribosomal structural domain by natural selection. Biochemistry 2006 0.82
19 General protocols for preparation of plasmid DNA template, RNA in vitro transcription, and RNA purification by denaturing PAGE. Methods Mol Biol 2012 0.82
20 Aminoglycoside resistance genes sgm and kgmB protect bacterial but not yeast small ribosomal subunits in vitro despite high conservation of the rRNA A-site. Res Microbiol 2008 0.81
21 Coevolution of protein and RNA structures within a highly conserved ribosomal domain. Chem Biol 2005 0.80
22 Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and disruption of a distant poly-(L-proline) II helix. Chem Senses 2011 0.79
23 Plasmid template design and in vitro transcription of short RNAs within a "structure cassette" for structure probing experiments. Methods Mol Biol 2012 0.78
24 Identification of new inhibitors of protein kinase R guided by statistical modeling. Bioorg Med Chem Lett 2011 0.78
25 Recombinant RNA expression. Nat Methods 2007 0.75
26 Heterologous Escherichia coli expression, purification and characterization of the GrmA aminoglycoside-resistance methyltransferase. Protein J 2009 0.75