Published in Cell Metab on August 19, 2010
A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell (2011) 9.24
microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice. J Clin Invest (2012) 1.84
miRNAs as serum biomarkers for Duchenne muscular dystrophy. EMBO Mol Med (2011) 1.80
Electrical stimulation counteracts muscle decline in seniors. Front Aging Neurosci (2014) 1.61
Expression analysis in multiple muscle groups and serum reveals complexity in the microRNA transcriptome of the mdx mouse with implications for therapy. Mol Ther Nucleic Acids (2012) 1.53
miR-31 modulates dystrophin expression: new implications for Duchenne muscular dystrophy therapy. EMBO Rep (2011) 1.50
Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis. J Clin Invest (2013) 1.42
Inhibition of miR-29 by TGF-beta-Smad3 signaling through dual mechanisms promotes transdifferentiation of mouse myoblasts into myofibroblasts. PLoS One (2012) 1.30
MicroRNAs in skeletal myogenesis. Cell Cycle (2011) 1.26
miR-29 targets Akt3 to reduce proliferation and facilitate differentiation of myoblasts in skeletal muscle development. Cell Death Dis (2013) 1.26
A feedforward regulatory loop between HuR and the long noncoding RNA linc-MD1 controls early phases of myogenesis. Mol Cell (2014) 1.24
Cyclin D1 is a major target of miR-206 in cell differentiation and transformation. Cell Cycle (2013) 1.16
Decreased miR-29 suppresses myogenesis in CKD. J Am Soc Nephrol (2011) 1.15
MicroRNA-199a is induced in dystrophic muscle and affects WNT signaling, cell proliferation, and myogenic differentiation. Cell Death Differ (2013) 1.14
S-nitrosylation: integrator of cardiovascular performance and oxygen delivery. J Clin Invest (2013) 1.12
Emerging drugs for Duchenne muscular dystrophy. Expert Opin Emerg Drugs (2012) 1.11
PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis. Cell Death Differ (2011) 1.11
Loss of miR-29 in myoblasts contributes to dystrophic muscle pathogenesis. Mol Ther (2012) 1.07
Histone deacetylase inhibitors in the treatment of muscular dystrophies: epigenetic drugs for genetic diseases. Mol Med (2011) 1.06
Attenuation of p38-mediated miR-1/133 expression facilitates myoblast proliferation during the early stage of muscle regeneration. PLoS One (2012) 1.05
MicroRNA in myogenesis and muscle atrophy. Curr Opin Clin Nutr Metab Care (2013) 1.04
HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles. Genes Dev (2014) 1.03
Distinctive serum miRNA profile in mouse models of striated muscular pathologies. PLoS One (2013) 1.03
Deregulated microRNAs in myotonic dystrophy type 2. PLoS One (2012) 1.01
Defective homocysteine metabolism: potential implications for skeletal muscle malfunction. Int J Mol Sci (2013) 0.99
Regulation of IRS1/Akt insulin signaling by microRNA-128a during myogenesis. J Cell Sci (2013) 0.94
MicroRNAs in skeletal muscle biology and exercise adaptation. Free Radic Biol Med (2013) 0.94
Hmgb3 is regulated by microRNA-206 during muscle regeneration. PLoS One (2012) 0.94
Exon 45 skipping through U1-snRNA antisense molecules recovers the Dys-nNOS pathway and muscle differentiation in human DMD myoblasts. Mol Ther (2012) 0.93
MicroRNA-486-dependent modulation of DOCK3/PTEN/AKT signaling pathways improves muscular dystrophy-associated symptoms. J Clin Invest (2014) 0.92
Integrative analysis of porcine microRNAome during skeletal muscle development. PLoS One (2013) 0.92
Novel long noncoding RNAs (lncRNAs) in myogenesis: a miR-31 overlapping lncRNA transcript controls myoblast differentiation. Mol Cell Biol (2014) 0.91
miR-411 is up-regulated in FSHD myoblasts and suppresses myogenic factors. Orphanet J Rare Dis (2013) 0.91
S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration. Proc Natl Acad Sci U S A (2013) 0.91
Epigenetic control of skeletal muscle regeneration: Integrating genetic determinants and environmental changes. FEBS J (2013) 0.89
Molecular mechanism of sphingosine-1-phosphate action in Duchenne muscular dystrophy. Dis Model Mech (2013) 0.89
Treatment with a nitric oxide-donating NSAID alleviates functional muscle ischemia in the mouse model of Duchenne muscular dystrophy. PLoS One (2012) 0.89
Altered expression and splicing of Ca(2+) metabolism genes in myotonic dystrophies DM1 and DM2. Neuropathol Appl Neurobiol (2013) 0.88
Laminin α2 Chain-Deficiency is Associated with microRNA Deregulation in Skeletal Muscle and Plasma. Front Aging Neurosci (2014) 0.88
Megarole for microRNA in muscle disease. Cell Metab (2010) 0.87
Dg-Dys-Syn1 signaling in Drosophila regulates the microRNA profile. BMC Cell Biol (2012) 0.86
MicroRNA-206: a promising theranostic marker. Theranostics (2014) 0.85
MicroRNA-206: a potential circulating biomarker candidate for amyotrophic lateral sclerosis. PLoS One (2014) 0.85
Interactions between muscle stem cells, mesenchymal-derived cells and immune cells in muscle homeostasis, regeneration and disease. Cell Death Dis (2015) 0.84
Stress-induced ECM alteration modulates cellular microRNAs that feedback to readjust the extracellular environment and cell behavior. Front Genet (2013) 0.84
Nitric oxide synthase deficiency and the pathophysiology of muscular dystrophy. J Physiol (2014) 0.84
Current and emerging treatment strategies for Duchenne muscular dystrophy. Neuropsychiatr Dis Treat (2016) 0.83
Recombinant adenoviral microRNA-206 induces myogenesis in C2C12 cells. Med Sci Monit (2011) 0.83
Long-term Exon Skipping Studies With 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides in Dystrophic Mouse Models. Mol Ther Nucleic Acids (2012) 0.83
SMYD1 and G6PD modulation are critical events for miR-206-mediated differentiation of rhabdomyosarcoma. Cell Cycle (2015) 0.83
Non-coding RNAs in muscle dystrophies. Int J Mol Sci (2013) 0.82
Impaired regeneration in LGMD2A supported by increased PAX7-positive satellite cell content and muscle-specific microrna dysregulation. Muscle Nerve (2013) 0.82
miRNA-based buffering of the cobblestone-lissencephaly-associated extracellular matrix receptor dystroglycan via its alternative 3'-UTR. Nat Commun (2014) 0.81
Overexpression of NF90-NF45 Represses Myogenic MicroRNA Biogenesis, Resulting in Development of Skeletal Muscle Atrophy and Centronuclear Muscle Fibers. Mol Cell Biol (2015) 0.81
Converging pathways involving microRNA-206 and the RNA-binding protein KSRP control post-transcriptionally utrophin A expression in skeletal muscle. Nucleic Acids Res (2013) 0.81
Loss of emerin alters myogenic signaling and miRNA expression in mouse myogenic progenitors. PLoS One (2012) 0.81
The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesis. Cell Death Dis (2016) 0.80
RBM4-MEF2C network constitutes a feed-forward circuit that facilitates the differentiation of brown adipocytes. RNA Biol (2015) 0.80
Functional muscle ischemia in Duchenne and Becker muscular dystrophy. Front Physiol (2013) 0.79
Dystrophin Orchestrates the Epigenetic Profile of Muscle Cells Via miRNAs. Front Genet (2011) 0.79
Kruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival. Oncogenesis (2015) 0.79
MicroRNA-431 accelerates muscle regeneration and ameliorates muscular dystrophy by targeting Pax7 in mice. Nat Commun (2015) 0.79
The role of microRNAs in the biology of rare diseases. Int J Mol Sci (2011) 0.78
Chromatin signaling in muscle stem cells: interpreting the regenerative microenvironment. Front Aging Neurosci (2015) 0.78
The absence of dystrophin brain isoform expression in healthy human heart ventricles explains the pathogenesis of 5' X-linked dilated cardiomyopathy. BMC Med Genet (2012) 0.78
Skeletal Muscle MicroRNAs: Their Diagnostic and Therapeutic Potential in Human Muscle Diseases. J Neuromuscul Dis (2016) 0.78
Detrimental effect of class-selective histone deacetylase inhibitors during tissue regeneration following hindlimb ischemia. J Biol Chem (2013) 0.77
Mast cell plasticity and sphingosine-1-phosphate in immunity, inflammation and cancer. Mol Immunol (2014) 0.77
Non-coding RNAs in muscle differentiation and musculoskeletal disease. J Clin Invest (2016) 0.77
Comparison of non-coding RNAs in human and canine cancer. Front Genet (2013) 0.77
Epigenetic alterations in muscular disorders. Comp Funct Genomics (2012) 0.77
MicroRNAs modulated by local mIGF-1 expression in mdx dystrophic mice. Front Aging Neurosci (2015) 0.77
Up-regulation of miR-31 in human atrial fibrillation begets the arrhythmia by depleting dystrophin and neuronal nitric oxide synthase. Sci Transl Med (2016) 0.76
Dystrophin and the two related genetic diseases, Duchenne and Becker muscular dystrophies. Bosn J Basic Med Sci (2015) 0.76
Postmitotic Expression of SOD1 (G93A) Gene Affects the Identity of Myogenic Cells and Inhibits Myoblasts Differentiation. Mediators Inflamm (2015) 0.76
The lack of the Celf2a splicing factor converts a Duchenne genotype into a Becker phenotype. Nat Commun (2016) 0.76
Characterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C2C12 Myocytes and mdx Mice. PLoS One (2016) 0.75
Identification in GRMD dog muscle of critical miRNAs involved in pathophysiology and effects associated with MuStem cell transplantation. BMC Musculoskelet Disord (2016) 0.75
S100B protein in skeletal muscle regeneration: regulation of myoblast and macrophage functions. Eur J Transl Myol (2016) 0.75
MicroRNA and mRNA Expression Changes in Steroid Naïve and Steroid Treated DMD Patients. J Neuromuscul Dis (2015) 0.75
Muscle-specific microRNAs as biomarkers of Duchenne Muscular Dystrophy progression and response to therapies. Rare Dis (2014) 0.75
Identification of β-Dystrobrevin as a Direct Target of miR-143: Involvement in Early Stages of Neural Differentiation. PLoS One (2016) 0.75
Circulating Biomarkers for Duchenne Muscular Dystrophy. J Neuromuscul Dis (2015) 0.75
New perspectives on the development of muscle contractures following central motor lesions. J Physiol (2016) 0.75
Glucose-6-phosphate dehydrogenase contributes to the regulation of glucose uptake in skeletal muscle. Mol Metab (2016) 0.75
Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma. Cancer Res (2016) 0.75
Transcriptional and Chromatin Dynamics of Muscle Regeneration after Severe Trauma. Stem Cell Reports (2016) 0.75
Circulating miRNAs are generic and versatile therapeutic monitoring biomarkers in muscular dystrophies. Sci Rep (2016) 0.75
Investigating Synthetic Oligonucleotide Targeting of Mir31 in Duchenne Muscular Dystrophy. PLoS Curr (2016) 0.75
Coordinated Actions of MicroRNAs with other Epigenetic Factors Regulate Skeletal Muscle Development and Adaptation. Int J Mol Sci (2017) 0.75
Decreased myoblast differentiation in chronic binge alcohol administered simian immunodeficiency virus-infected male macaques: role of decreased miR-206. Am J Physiol Regul Integr Comp Physiol (2017) 0.75
Acute resistance exercise modulates microRNA expression profiles: Combined tissue and circulatory targeted analyses. PLoS One (2017) 0.75
Upregulation of circulating myomiR following short-term energy restriction is inversely associated with whole-body protein synthesis. Am J Physiol Regul Integr Comp Physiol (2017) 0.75
Integration of miRNA and mRNA expression profiles reveals microRNA-regulated networks during muscle wasting in cardiac cachexia. Sci Rep (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Safety and efficacy of gene transfer for Leber's congenital amaurosis. N Engl J Med (2008) 17.21
A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell (2011) 9.24
A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis. Cell (2005) 9.22
Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial. Lancet (2009) 6.71
Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration. Mol Ther (2009) 3.93
Primary microRNA transcripts are processed co-transcriptionally. Nat Struct Mol Biol (2008) 3.21
AAV2 gene therapy readministration in three adults with congenital blindness. Sci Transl Med (2012) 2.87
Clinical and molecular genetics of Leber's congenital amaurosis: a multicenter study of Italian patients. Invest Ophthalmol Vis Sci (2007) 2.69
Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model. J Cell Biol (2005) 2.61
Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice. J Clin Invest (2008) 2.40
Skeletal muscle is a primary target of SOD1G93A-mediated toxicity. Cell Metab (2008) 2.34
Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport. J Clin Invest (2004) 2.30
Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells. EMBO J (2008) 2.25
MicroRNA profiling in human medulloblastoma. Int J Cancer (2009) 2.12
Novel adeno-associated virus serotypes efficiently transduce murine photoreceptors. J Virol (2007) 2.05
Three-year follow-up after unilateral subretinal delivery of adeno-associated virus in patients with Leber congenital Amaurosis type 2. Ophthalmology (2013) 1.85
miRNAs as serum biomarkers for Duchenne muscular dystrophy. EMBO Mol Med (2011) 1.80
Local expression of IGF-1 accelerates muscle regeneration by rapidly modulating inflammatory cytokines and chemokines. FASEB J (2007) 1.76
The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells. Proc Natl Acad Sci U S A (2007) 1.68
CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery. J Biol Chem (2008) 1.62
A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation. Nucleic Acids Res (2010) 1.58
Body-wide gene therapy of Duchenne muscular dystrophy in the mdx mouse model. Proc Natl Acad Sci U S A (2006) 1.55
Coupled RNA processing and transcription of intergenic primary microRNAs. Mol Cell Biol (2009) 1.54
The human visual cortex responds to gene therapy-mediated recovery of retinal function. J Clin Invest (2011) 1.52
Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material. Hum Gene Ther (2010) 1.51
Purified box C/D snoRNPs are able to reproduce site-specific 2'-O-methylation of target RNA in vitro. Mol Cell Biol (2002) 1.50
miR-31 modulates dystrophin expression: new implications for Duchenne muscular dystrophy therapy. EMBO Rep (2011) 1.50
Functional analysis of yeast snoRNA and snRNA 3'-end formation mediated by uncoupling of cleavage and polyadenylation. Mol Cell Biol (2002) 1.49
Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia. Blood (2007) 1.48
A new vector, based on the PolII promoter of the U1 snRNA gene, for the expression of siRNAs in mammalian cells. Mol Ther (2004) 1.48
RNA interference-mediated suppression and replacement of human rhodopsin in vivo. Am J Hum Genet (2007) 1.47
Versatility of AAV vectors for retinal gene transfer. Vision Res (2007) 1.44
Long-term high-level exercise promotes muscle reinnervation with age. J Neuropathol Exp Neurol (2014) 1.40
Purification, cloning, and characterization of XendoU, a novel endoribonuclease involved in processing of intron-encoded small nucleolar RNAs in Xenopus laevis. J Biol Chem (2003) 1.40
Natural antisense transcripts associated with genes involved in eye development. Hum Mol Genet (2005) 1.40
Systemic but not intraocular Epo gene transfer protects the retina from light-and genetic-induced degeneration. Mol Ther (2004) 1.35
FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment. EMBO J (2012) 1.35
Msx2 and necdin combined activities are required for smooth muscle differentiation in mesoangioblast stem cells. Circ Res (2004) 1.33
p66(ShcA) and oxidative stress modulate myogenic differentiation and skeletal muscle regeneration after hind limb ischemia. J Biol Chem (2007) 1.27
Colony shape as a genetic trait in the pattern-forming Bacillus mycoides. BMC Microbiol (2002) 1.25
Increased IGF-1 in muscle modulates the phenotype of severe SMA mice. Hum Mol Genet (2011) 1.24
The cotranscriptional assembly of snoRNPs controls the biosynthesis of H/ACA snoRNAs in Saccharomyces cerevisiae. Mol Cell Biol (2005) 1.24
Chimeric snRNA molecules carrying antisense sequences against the splice junctions of exon 51 of the dystrophin pre-mRNA induce exon skipping and restoration of a dystrophin synthesis in Delta 48-50 DMD cells. Proc Natl Acad Sci U S A (2002) 1.24
Adaptation of mouse skeletal muscle to long-term microgravity in the MDS mission. PLoS One (2012) 1.23
Correction of Hunter syndrome in the MPSII mouse model by AAV2/8-mediated gene delivery. Hum Mol Genet (2006) 1.21
Biochemical, pathological, and skeletal improvement of mucopolysaccharidosis VI after gene transfer to liver but not to muscle. Mol Ther (2007) 1.21
Functional correction of CNS lesions in an MPS-IIIA mouse model by intracerebral AAV-mediated delivery of sulfamidase and SUMF1 genes. Hum Mol Genet (2007) 1.20
Atrophy/hypertrophy cell signaling in muscles of young athletes trained with vibrational-proprioceptive stimulation. Neurol Res (2011) 1.19
Reconstitution of the entire hepatitis C virus life cycle in nonhepatic cells. J Virol (2012) 1.18
Long-term benefit of adeno-associated virus/antisense-mediated exon skipping in dystrophic mice. Hum Gene Ther (2008) 1.17
AAV-mediated gene transfer for retinal diseases. Expert Opin Biol Ther (2006) 1.15
PEGylation of a vesicular stomatitis virus G pseudotyped lentivirus vector prevents inactivation in serum. J Virol (2004) 1.15
Functional characterization of XendoU, the endoribonuclease involved in small nucleolar RNA biosynthesis. J Biol Chem (2005) 1.13
Filamin A is mutated in X-linked chronic idiopathic intestinal pseudo-obstruction with central nervous system involvement. Am J Hum Genet (2007) 1.13
Counteracting muscle wasting in aging and neuromuscular diseases: the critical role of IGF-1. Aging (Albany NY) (2009) 1.13
Chimeric adeno-associated virus/antisense U1 small nuclear RNA effectively rescues dystrophin synthesis and muscle function by local treatment of mdx mice. Hum Gene Ther (2006) 1.11
Disease rescue and increased lifespan in a model of cardiomyopathy and muscular dystrophy by combined AAV treatments. PLoS One (2009) 1.09
Exon skipping and duchenne muscular dystrophy therapy: selection of the most active U1 snRNA antisense able to induce dystrophin exon 51 skipping. Mol Ther (2010) 1.09
Coupling between snoRNP assembly and 3' processing controls box C/D snoRNA biosynthesis in yeast. EMBO J (2004) 1.09
ROCK2 and its alternatively spliced isoform ROCK2m positively control the maturation of the myogenic program. Mol Cell Biol (2007) 1.09
Correlation between photoreceptor layer integrity and visual function in patients with Stargardt disease: implications for gene therapy. Invest Ophthalmol Vis Sci (2012) 1.09
Impact of ageing on muscle cell regeneration. Ageing Res Rev (2009) 1.08
Long-term inducible gene expression in the eye via adeno-associated virus gene transfer in nonhuman primates. Hum Gene Ther (2005) 1.07
Long-term amelioration of feline Mucopolysaccharidosis VI after AAV-mediated liver gene transfer. Mol Ther (2010) 1.06
Abnormal autophagy, ubiquitination, inflammation and apoptosis are dependent upon lysosomal storage and are useful biomarkers of mucopolysaccharidosis VI. Pathogenetics (2009) 1.06
Stress induces region specific alterations in microRNAs expression in mice. Behav Brain Res (2009) 1.06
Alpha4beta1 integrin acts as a cell receptor for murine polyomavirus at the postattachment level. J Virol (2003) 1.06
Worsening of cardiomyopathy using deflazacort in an animal model rescued by gene therapy. PLoS One (2011) 1.05