Autism in fragile X syndrome: a category mistake?

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A developmental, longitudinal investigation of autism phenotypic profiles in fragile X syndrome. J Neurodev Disord (2016) 1.39

Networking in autism: leveraging genetic, biomarker and model system findings in the search for new treatments. Neuropsychopharmacology (2011) 1.15

What can we learn about autism from studying fragile X syndrome? Dev Neurosci (2011) 1.11

Effects of sampling context on spontaneous expressive language in males with fragile X syndrome or Down syndrome. J Speech Lang Hear Res (2012) 1.11

Evidence of a distinct behavioral phenotype in young boys with fragile X syndrome and autism. J Am Acad Child Adolesc Psychiatry (2012) 1.10

Lessons learned from studying syndromic autism spectrum disorders. Nat Neurosci (2016) 1.04

Trajectories of early brain volume development in fragile X syndrome and autism. J Am Acad Child Adolesc Psychiatry (2012) 0.98

Defining genetically meaningful language and personality traits in relatives of individuals with fragile X syndrome and relatives of individuals with autism. Am J Med Genet B Neuropsychiatr Genet (2012) 0.96

Investigating word learning in fragile X syndrome: a fast-mapping study. J Autism Dev Disord (2013) 0.95

Contributions of phonological and verbal working memory to language development in adolescents with fragile X syndrome. J Neurodev Disord (2011) 0.92

Repetitive and self-injurious behaviors: associations with caudate volume in autism and fragile X syndrome. J Neurodev Disord (2013) 0.92

Symptoms of Autism in Males with Fragile X Syndrome: A Comparison to Nonsyndromic ASD Using Current ADI-R Scores. J Autism Dev Disord (2015) 0.91

Early identification of autism in fragile X syndrome: a review. J Intellect Disabil Res (2012) 0.91

Early negative affect predicts anxiety, not autism, in preschool boys with fragile X syndrome. J Abnorm Child Psychol (2013) 0.88

Autism Symptomatology in Boys with Fragile X Syndrome: A Cross Sectional Developmental Trajectories Comparison with Nonsyndromic Autism Spectrum Disorder. J Autism Dev Disord (2015) 0.87

Intervention in the context of development: pathways toward new treatments. Neuropsychopharmacology (2014) 0.86

Identifying large-scale brain networks in fragile X syndrome. JAMA Psychiatry (2013) 0.86

Behavioral signatures related to genetic disorders in autism. Mol Autism (2014) 0.84

A comparison of pragmatic language in boys with autism and fragile X syndrome. J Speech Lang Hear Res (2014) 0.84

The origin and natural history of autism spectrum disorders. Nat Neurosci (2016) 0.82

A 'learning platform' approach to outcome measurement in fragile X syndrome: a preliminary psychometric study. J Intellect Disabil Res (2012) 0.81

DSM-5 changes and the prevalence of parent-reported autism spectrum symptoms in Fragile X syndrome. J Autism Dev Disord (2015) 0.80

FRAGILE X SYNDROME: PSYCHIATRIC MANIFESTATIONS, ASSESSMENT AND EMERGING THERAPIES. Curr Psychiatry Rev (2013) 0.80

Effect of speaker gaze on word learning in fragile X syndrome: a comparison with nonsyndromic autism spectrum disorder. J Speech Lang Hear Res (2015) 0.79

Novel roles of amyloid-beta precursor protein metabolites in fragile X syndrome and autism. Mol Psychiatry (2016) 0.79

Finding novel distinctions between the sAPPα-mediated anabolic biochemical pathways in Autism Spectrum Disorder and Fragile X Syndrome plasma and brain tissue. Sci Rep (2016) 0.79

Cardiac autonomic regulation in autism and Fragile X syndrome: a review. Psychol Bull (2014) 0.78

A Spoken-Language Intervention for School-Aged Boys With Fragile X Syndrome. Am J Intellect Dev Disabil (2016) 0.78

Presence of autism, hyperserotonemia, and severe expressive language impairment in Williams-Beuren syndrome. Mol Autism (2013) 0.78

Updated report on tools to measure outcomes of clinical trials in fragile X syndrome. J Neurodev Disord (2017) 0.77

Effects of labeling and pointing on object gaze in boys with fragile X syndrome: an eye-tracking study. Res Dev Disabil (2014) 0.77

Characterising repetitive behaviours in young boys with fragile X syndrome. J Intellect Disabil Res (2015) 0.77

Amygdala regulation of fear and emotionality in fragile X syndrome. Dev Neurosci (2011) 0.77

The relationship between autistic symptomatology and independent living skills in adolescents and young adults with fragile X syndrome. J Autism Dev Disord (2015) 0.75

Signaling of noncomprehension in communication breakdowns in fragile X syndrome, Down syndrome, and autism spectrum disorder. J Commun Disord (2017) 0.75

High-functioning autism spectrum disorder and fragile X syndrome: report of two affected sisters. Mol Autism (2012) 0.75

Joint Engagement and Early Language in Young Children With Fragile X Syndrome. J Speech Lang Hear Res (2016) 0.75

Investigating Autism-Related Symptoms in Children with Prader-Willi Syndrome: A Case Study. Int J Mol Sci (2017) 0.75

Autism Spectrum Disorder Symptoms in Infants with Fragile X Syndrome: A Prospective Case Series. J Autism Dev Disord (2017) 0.75

Autism Spectrum Disorder in Fragile X Syndrome: Cooccurring Conditions and Current Treatment. Pediatrics (2017) 0.75

Language Skills of Males with Fragile X Syndrome or Nonsyndromic Autism Spectrum Disorder. J Autism Dev Disord (2017) 0.75

Effects of a social stimulus on gene expression in a mouse model of fragile X syndrome. Mol Autism (2017) 0.75

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell (1991) 17.00

Autism diagnostic observation schedule: a standardized observation of communicative and social behavior. J Autism Dev Disord (1989) 7.53

Autism screening questionnaire: diagnostic validity. Br J Psychiatry (1999) 6.61

Time to give up on a single explanation for autism. Nat Neurosci (2006) 3.87

The behavioral phenotype in fragile X: symptoms of autism in very young children with fragile X syndrome, idiopathic autism, and other developmental disorders. J Dev Behav Pediatr (2001) 3.64

Autistic behavior in children with fragile X syndrome: prevalence, stability, and the impact of FMRP. Am J Med Genet A (2006) 2.61

Autism spectrum disorder in fragile X syndrome: communication, social interaction, and specific behaviors. Am J Med Genet A (2004) 2.58

Autism profiles of males with fragile X syndrome. Am J Ment Retard (2008) 2.35

The epidemiology of autistic spectrum disorders: is the prevalence rising? Ment Retard Dev Disabil Res Rev (2002) 2.30

Autistic behavior, FMR1 protein, and developmental trajectories in young males with fragile X syndrome. J Autism Dev Disord (2001) 2.29

Autism spectrum phenotype in males and females with fragile X full mutation and premutation. J Autism Dev Disord (2007) 2.28

Autistic behavior in young boys with fragile X syndrome. J Autism Dev Disord (1998) 1.91

Caudate nucleus is enlarged in high-functioning medication-naive subjects with autism. Biol Psychiatry (2007) 1.70

Neuroanatomy of fragile X syndrome is associated with aberrant behavior and the fragile X mental retardation protein (FMRP). Ann Neurol (2008) 1.66

Rapid antibody test for diagnosing fragile X syndrome: a validation of the technique. Hum Genet (1997) 1.59

Linguistic and cognitive functioning and autism symptoms in young children with fragile X syndrome. Am J Ment Retard (2004) 1.58

Social behavior profile in young males with fragile X syndrome: characteristics and specificity. Am J Med Genet A (2004) 1.56

Longitudinal study of amygdala volume and joint attention in 2- to 4-year-old children with autism. Arch Gen Psychiatry (2009) 1.54

From complexity to category: responding to diagnostic uncertainties of autistic spectrum disorders. J Paediatr Child Health (2005) 1.52

Compulsive, self-injurious, and autistic behavior in children and adolescents with fragile X syndrome. Am J Ment Retard (2008) 1.43

Teasing apart the heterogeneity of autism: Same behavior, different brains in toddlers with fragile X syndrome and autism. J Neurodev Disord (2009) 1.42

An analysis of autism in fifty males with the fragile X syndrome. Am J Med Genet (1986) 1.38

The near universal presence of autism spectrum disorders in children with Smith-Lemli-Opitz syndrome. Am J Med Genet A (2006) 1.37

Autism in Angelman syndrome: implications for autism research. Clin Genet (2004) 1.37

Autism spectrum disorders in genetic syndromes: implications for diagnosis, intervention and understanding the wider autism spectrum disorder population. J Intellect Disabil Res (2009) 1.34

Autism spectrum disorder in fragile X syndrome: a longitudinal evaluation. Am J Med Genet A (2009) 1.33

The influence of environmental and genetic factors on behavior problems and autistic symptoms in boys and girls with fragile X syndrome. Pediatrics (2001) 1.32

Socio-communicative deficits in young children with Williams syndrome: performance on the Autism Diagnostic Observation Schedule. Child Neuropsychol (2007) 1.21

Conversational analyses of males with fragile X, Down syndrome, and autism: comparison of the emergence of deviant language. Am J Ment Retard (1990) 1.16

Brain anatomy, gender and IQ in children and adolescents with fragile X syndrome. Brain (2001) 1.13

Autism spectrum disorder in Fragile X syndrome: differential contribution of adaptive socialization and social withdrawal. Am J Med Genet A (2006) 1.13

Physiological correlates of social avoidance behavior in children and adolescents with fragile x syndrome. J Am Acad Child Adolesc Psychiatry (2009) 1.07

Fragile X syndrome: assessment and treatment implications. Child Adolesc Psychiatr Clin N Am (2007) 1.06

Autism is associated with the fragile-X syndrome. J Autism Dev Disord (1982) 1.05

Using percentile schedules to increase eye contact in children with Fragile X syndrome. J Appl Behav Anal (2009) 1.02

Autism and phenylketonuria. J Autism Dev Disord (2003) 1.00

Autistic-like behavior in CHARGE syndrome. Am J Med Genet A (2005) 1.00

Effects of age and communication level on eye contact in fragile X males and non-fragile X autistic males. Am J Med Genet (1991) 0.98

Parent-child dyadic gaze patterns in fragile X males and in non-fragile X males with autistic disorder. J Child Psychol Psychiatry (1989) 0.97

Behavioural and cognitive phenotypes in idiopathic autism versus autism associated with fragile X syndrome. J Child Psychol Psychiatry (2008) 0.97

The acquisition of stimulus equivalence in individuals with fragile X syndrome. J Intellect Disabil Res (2006) 0.93

Childhood developmental disorders: an academic and clinical convergence point for psychiatry, neurology, psychology and pediatrics. J Child Psychol Psychiatry (2009) 0.93

Treatments for fragile X syndrome: a closer look at the data. Dev Disabil Res Rev (2009) 0.91

Autism spectrum disorders and underlying brain pathology in CHARGE association. Dev Med Child Neurol (2006) 0.87

Is autism associated with the fragile X syndrome? Am J Med Genet (1992) 0.84

Brief report: autism in individuals with Down syndrome. J Autism Dev Disord (2005) 0.83

What is associated with the fragile X syndrome? Am J Med Genet (1993) 0.83

Autism is not associated with the fragile X syndrome. Am J Med Genet (1989) 0.79

Detrimental effects of overestimating the occurrence of autism. Intellect Dev Disabil (2008) 0.77

Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci U S A (2002) 31.14

Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc Natl Acad Sci U S A (2004) 19.84

Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci (2007) 19.58

Resting-state functional connectivity in major depression: abnormally increased contributions from subgenual cingulate cortex and thalamus. Biol Psychiatry (2007) 9.08

White matter development during childhood and adolescence: a cross-sectional diffusion tensor imaging study. Cereb Cortex (2005) 4.07

White matter structure in autism: preliminary evidence from diffusion tensor imaging. Biol Psychiatry (2004) 3.70

Persistent default-mode network connectivity during light sedation. Hum Brain Mapp (2008) 3.66

The amygdala is enlarged in children but not adolescents with autism; the hippocampus is enlarged at all ages. J Neurosci (2004) 3.30

Maturation of brain function associated with response inhibition. J Am Acad Child Adolesc Psychiatry (2002) 3.00

A developmental fMRI study of the Stroop color-word task. Neuroimage (2002) 2.61

Early white-matter abnormalities of the ventral frontostriatal pathway in fragile X syndrome. Dev Med Child Neurol (2009) 2.38

A quantitative comparison of NIRS and fMRI across multiple cognitive tasks. Neuroimage (2010) 2.29

Stress predicts brain changes in children: a pilot longitudinal study on youth stress, posttraumatic stress disorder, and the hippocampus. Pediatrics (2007) 2.26

Towards effective and rewarding data sharing. Neuroinformatics (2003) 2.24

COMT genotype predicts longitudinal cognitive decline and psychosis in 22q11.2 deletion syndrome. Nat Neurosci (2005) 2.21

Abnormal cortical complexity and thickness profiles mapped in Williams syndrome. J Neurosci (2005) 2.15

Functional and morphometric brain dissociation between dyslexia and reading ability. Proc Natl Acad Sci U S A (2007) 2.05

Risk factors for the emergence of psychotic disorders in adolescents with 22q11.2 deletion syndrome. Am J Psychiatry (2007) 2.04

Neural systems predicting long-term outcome in dyslexia. Proc Natl Acad Sci U S A (2010) 1.95

Symmetry of cortical folding abnormalities in Williams syndrome revealed by surface-based analyses. J Neurosci (2006) 1.90

Humor modulates the mesolimbic reward centers. Neuron (2003) 1.83

Diurnal salivary cortisol in pediatric posttraumatic stress disorder. Biol Psychiatry (2002) 1.80

Neuroanatomical correlates of dysglycemia in young children with type 1 diabetes. Diabetes (2013) 1.78

NIRS-based hyperscanning reveals increased interpersonal coherence in superior frontal cortex during cooperation. Neuroimage (2011) 1.76

More is not always better: increased fractional anisotropy of superior longitudinal fasciculus associated with poor visuospatial abilities in Williams syndrome. J Neurosci (2007) 1.73

Decreased prefrontal cortical volume associated with increased bedtime cortisol in traumatized youth. Biol Psychiatry (2010) 1.72

Functional near infrared spectroscopy (NIRS) signal improvement based on negative correlation between oxygenated and deoxygenated hemoglobin dynamics. Neuroimage (2009) 1.70

Psychiatric disorders and behavioral problems in children with velocardiofacial syndrome: usefulness as phenotypic indicators of schizophrenia risk. Biol Psychiatry (2002) 1.69

Neuroanatomy of fragile X syndrome is associated with aberrant behavior and the fragile X mental retardation protein (FMRP). Ann Neurol (2008) 1.66

3D pattern of brain abnormalities in Williams syndrome visualized using tensor-based morphometry. Neuroimage (2007) 1.62

Defining the social phenotype in Williams syndrome: a model for linking gene, the brain, and behavior. Dev Psychopathol (2008) 1.61

Toward an empirical definition of pediatric PTSD: the phenomenology of PTSD symptoms in youth. J Am Acad Child Adolesc Psychiatry (2002) 1.60

Parietal attentional system aberrations during target detection in adolescents with attention deficit hyperactivity disorder: event-related fMRI evidence. Am J Psychiatry (2006) 1.55

Amygdalar activation associated with positive and negative facial expressions. Neuroreport (2002) 1.55

Volumetric analysis of regional cerebral development in preterm children. Pediatr Neurol (2004) 1.53

Event-related FMRI evidence of frontotemporal involvement in aberrant response inhibition and task switching in attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry (2004) 1.52

Functional brain activation during arithmetic processing in females with fragile X Syndrome is related to FMR1 protein expression. Hum Brain Mapp (2002) 1.46

Brain volume reductions within multiple cognitive systems in male preterm children at age twelve. J Pediatr (2007) 1.46

Compulsive, self-injurious, and autistic behavior in children and adolescents with fragile X syndrome. Am J Ment Retard (2008) 1.43

Teasing apart the heterogeneity of autism: Same behavior, different brains in toddlers with fragile X syndrome and autism. J Neurodev Disord (2009) 1.42

ADHD- and medication-related brain activation effects in concordantly affected parent-child dyads with ADHD. J Child Psychol Psychiatry (2007) 1.40

Emotional attribution in high-functioning individuals with autistic spectrum disorder: a functional imaging study. J Am Acad Child Adolesc Psychiatry (2004) 1.39

Automated extraction of the cortical sulci based on a supervised learning approach. IEEE Trans Med Imaging (2007) 1.37

Morphometric spatial patterns differentiating boys with fragile X syndrome, typically developing boys, and developmentally delayed boys aged 1 to 3 years. Arch Gen Psychiatry (2008) 1.36

3D pattern of brain abnormalities in Fragile X syndrome visualized using tensor-based morphometry. Neuroimage (2006) 1.34

Longitudinal brain volume changes in preterm and term control subjects during late childhood and adolescence. Pediatrics (2009) 1.31

The neuroanatomy and neuroendocrinology of fragile X syndrome. Ment Retard Dev Disabil Res Rev (2004) 1.31

White matter tract alterations in fragile X syndrome: preliminary evidence from diffusion tensor imaging. Am J Med Genet B Neuropsychiatr Genet (2003) 1.31

Aberrant brain activation during a response inhibition task in adolescent eating disorder subtypes. Am J Psychiatry (2010) 1.31

A solution to limitations of cognitive testing in children with intellectual disabilities: the case of fragile X syndrome. J Neurodev Disord (2009) 1.31

Increased local gyrification mapped in Williams syndrome. Neuroimage (2006) 1.30

Regional analysis of hippocampal activation during memory encoding and retrieval: fMRI study. Hippocampus (2003) 1.29

Prediction of children's reading skills using behavioral, functional, and structural neuroimaging measures. Behav Neurosci (2007) 1.27

Region-specific alterations in brain development in one- to three-year-old boys with fragile X syndrome. Proc Natl Acad Sci U S A (2010) 1.27

Effects of X-monosomy and X-linked imprinting on superior temporal gyrus morphology in Turner syndrome. Biol Psychiatry (2003) 1.27

Developmental trajectories of brain structure in adolescents with 22q11.2 deletion syndrome: a longitudinal study. Schizophr Res (2007) 1.26

Functional neuroanatomy of spatial orientation processing in Turner syndrome. Cereb Cortex (2004) 1.25

Gender differences in the mesocorticolimbic system during computer game-play. J Psychiatr Res (2008) 1.25

Hippocampal volume, PTSD, and alcoholism in combat veterans. Am J Psychiatry (2006) 1.24

Reduced hippocampal activity in youth with posttraumatic stress symptoms: an FMRI study. J Pediatr Psychol (2009) 1.23

Psychometric study of the Aberrant Behavior Checklist in Fragile X Syndrome and implications for targeted treatment. J Autism Dev Disord (2012) 1.23

To modulate or not to modulate: differing results in uniquely shaped Williams syndrome brains. Neuroimage (2006) 1.22

Cortical magnetic resonance imaging findings in familial pediatric bipolar disorder. Biol Psychiatry (2005) 1.22

Preterm birth results in alterations in neural connectivity at age 16 years. Neuroimage (2010) 1.22

Posttraumatic stress symptoms and brain function during a response-inhibition task: an fMRI study in youth. Depress Anxiety (2008) 1.20

Limbic and corpus callosum aberrations in adolescents with bipolar disorder: a tract-based spatial statistics analysis. Biol Psychiatry (2009) 1.19

Similar white matter aberrations in children with autism and their unaffected siblings: a diffusion tensor imaging study using tract-based spatial statistics. Arch Gen Psychiatry (2010) 1.19

Aberrant frontal lobe maturation in adolescents with fragile X syndrome is related to delayed cognitive maturation. Biol Psychiatry (2011) 1.19

Alterations in functional connectivity for language in prematurely born adolescents. Brain (2009) 1.18

Social behavior and cortisol reactivity in children with fragile X syndrome. J Child Psychol Psychiatry (2006) 1.18

Alterations in white matter structure in young children with type 1 diabetes. Diabetes Care (2013) 1.17

Applying tensor-based morphometry to parametric surfaces can improve MRI-based disease diagnosis. Neuroimage (2013) 1.17

Fronto-striatal dysfunction and potential compensatory mechanisms in male adolescents with fragile X syndrome. Hum Brain Mapp (2007) 1.16

The fusiform face area is enlarged in Williams syndrome. J Neurosci (2010) 1.16

Increased temporal lobe gyrification in preterm children. Neuropsychologia (2005) 1.16

Arithmetic ability and parietal alterations: a diffusion tensor imaging study in velocardiofacial syndrome. Brain Res Cogn Brain Res (2005) 1.15

Investigation of neuroanatomical differences between autism and Asperger syndrome. Arch Gen Psychiatry (2004) 1.14

Autism and the development of face processing. Clin Neurosci Res (2006) 1.14

The feasibility of detecting neuropsychologic and neuroanatomic effects of type 1 diabetes in young children. Diabetes Care (2011) 1.14

Personality predicts activity in reward and emotional regions associated with humor. Proc Natl Acad Sci U S A (2005) 1.14

Brain development in Turner syndrome: a magnetic resonance imaging study. Psychiatry Res (2002) 1.14

Longitudinal changes in intellectual development in children with Fragile X syndrome. J Abnorm Child Psychol (2008) 1.12

Neuroanatomic variation in monozygotic twin pairs discordant for the narrow phenotype for autism. Am J Psychiatry (2004) 1.12

Here's looking at you, kid: neural systems underlying face and gaze processing in fragile X syndrome. Arch Gen Psychiatry (2004) 1.12

Neural correlates of auditory perception in Williams syndrome: an fMRI study. Neuroimage (2003) 1.12

Future of genetics of mood disorders research. Biol Psychiatry (2002) 1.11

Assessment and prevention of head motion during imaging of patients with attention deficit hyperactivity disorder. Psychiatry Res (2007) 1.11

Frontostriatal dysfunction during response inhibition in Williams syndrome. Biol Psychiatry (2006) 1.11

Outcome measures for clinical trials in fragile X syndrome. J Dev Behav Pediatr (2013) 1.10

The brain basis of the phonological deficit in dyslexia is independent of IQ. Psychol Sci (2011) 1.10

Effects of intranasal oxytocin on social anxiety in males with fragile X syndrome. Psychoneuroendocrinology (2011) 1.10