C G Parsons

Author PubWeight™ 46.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Glycine and N-methyl-D-aspartate receptors: physiological significance and possible therapeutic applications. Pharmacol Rev 1998 2.28
2 COMPLETE AURICULO-VENTRICULAR DISSOCIATION WITH HIGH VENTRICULAR RATE IN PAROXYSMAL TACHYCARDIA. Br Heart J 1943 1.34
3 Aminoadamantanes as NMDA receptor antagonists and antiparkinsonian agents--preclinical studies. Neurosci Biobehav Rev 1997 1.27
4 The N-methyl-D-aspartate receptor channel blockers memantine, MRZ 2/579 and other amino-alkyl-cyclohexanes antagonise 5-HT(3) receptor currents in cultured HEK-293 and N1E-115 cell systems in a non-competitive manner. Neurosci Lett 2001 1.20
5 Haemodynamic effects of balloon septostomy in tricuspid atresia. Br Med J 1968 1.10
6 The role of N-methylaspartate receptors in mediating responses of rat and cat spinal neurones to defined sensory stimuli. J Physiol 1987 1.08
7 Pulmonary artery banding and subsequent repair in ventricular septal defect. Br Heart J 1973 1.08
8 Pharmacodynamics of memantine: an update. Curr Neuropharmacol 2008 1.03
9 Effects of memantine on recombinant rat NMDA receptors expressed in HEK 293 cells. Br J Pharmacol 1996 0.98
10 Effects of memantine and MK-801 on NMDA-induced currents in cultured neurones and on synaptic transmission and LTP in area CA1 of rat hippocampal slices. Br J Pharmacol 1996 0.98
11 Uncompetitive NMDA receptor antagonists attenuate NMDA-induced impairment of passive avoidance learning and LTP. Neuropharmacology 1997 0.97
12 Alpha2-adrenoreceptor activation inhibits LTP and LTD in the basolateral amygdala: involvement of Gi/o-protein-mediated modulation of Ca2+-channels and inwardly rectifying K+-channels in LTD. Eur J Neurosci 2003 0.97
13 Effects of the uncompetitive NMDA receptor antagonist memantine on hippocampal long-term potentiation, short-term exploratory modulation and spatial memory in awake, freely moving rats. Eur J Neurosci 1996 0.96
14 Transposition of great arteries. A study of 65 infants followed for 1 to 4 years after balloon septostomy. Br Heart J 1971 0.96
15 Memantine restores long term potentiation impaired by tonic N-methyl-D-aspartate (NMDA) receptor activation following reduction of Mg2+ in hippocampal slices. Neuropharmacology 1999 0.95
16 Different binding affinities of NMDA receptor channel blockers in various brain regions--indication of NMDA receptor heterogeneity. Neuropharmacology 1995 0.94
17 Neuroprotective and symptomatological action of memantine relevant for Alzheimer's disease--a unified glutamatergic hypothesis on the mechanism of action. Neurotox Res 2000 0.92
18 Flupirtine shows functional NMDA receptor antagonism by enhancing Mg2+ block via activation of voltage independent potassium channels. Rapid communication. J Neural Transm (Vienna) 1999 0.89
19 Learning deficits induced by chronic intraventricular infusion of quinolinic acid--protection by MK-801 and memantine. Eur J Pharmacol 1996 0.88
20 Interactions of GYKI 52466 and NBQX with cyclothiazide at AMPA receptors: experiments with outside-out patches and EPSCs in hippocampal neurones. Neuropharmacology 1999 0.87
21 Recurrence of aortic coarctation after operation in childhood. Br Med J 1966 0.86
22 Comparison of mu, kappa and sigma preferring agonists for effects on spinal nociceptive and other responses in rats. Neuropeptides 1984 0.86
23 Effects of intravenous mu and kappa opioid receptor agonists on sensory responses of convergent neurones in the dorsal horn of spinalized rats. Br J Pharmacol 1991 0.85
24 GlycineB antagonists as potential therapeutic agents. Previous hopes and present reality. Amino Acids 1998 0.85
25 Anxiolytic activity of glycine-B antagonists and partial agonists--no relation to intrinsic activity in the patch clamp. Neuropharmacology 1997 0.84
26 Agonist concentration dependency of blocking kinetics but not equilibrium block of N-methyl-D-aspartate receptors by memantine. Neuropharmacology 2007 0.84
27 Electrophysiological study, biodistribution in mice, and preliminary PET evaluation in a rhesus monkey of 1-amino-3-[18F]fluoromethyl-5-methyl-adamantane (18F-MEM): a potential radioligand for mapping the NMDA-receptor complex. Nucl Med Biol 1998 0.83
28 Expression of early hippocampal CA1 LTP does not lead to changes in AMPA-EPSC kinetics or sensitivity to cyclothiazide. Pflugers Arch 1999 0.82
29 Synthesis and structure-affinity relationships of 1,3, 5-alkylsubstituted cyclohexylamines binding at NMDA receptor PCP site. Eur J Med Chem 2000 0.82
30 Amino-alkyl-cyclohexanes as a novel class of uncompetitive NMDA receptor antagonists. Curr Pharm Des 2002 0.82
31 Recurrent coarctation of the aorta. Am Heart J 1967 0.81
32 Memantine selectively depresses NMDA receptor-mediated responses of ratspinal neurones in vivo. Neurosci Lett 1994 0.80
33 Interactions of 2,3-benzodiazepines and cyclothiazide at AMPA receptors: patch clamp recordings in cultured neurones and area CA1 in hippocampal slices. Br J Pharmacol 1996 0.80
34 NMDA channel blockers: memantine and amino-aklylcyclohexanes--in vivo characterization. Amino Acids 2000 0.80
35 Differential effects of NMDA-receptor antagonists on long-term potentiation and hypoxic/hypoglycaemic excitotoxicity in hippocampal slices. Neuropharmacology 2000 0.80
36 Autoradiographic and electrophysiological evidence for excitatory amino acid transmission in the periaqueductal gray projection to nucleus raphe magnus in the rat. Neurosci Lett 1988 0.80
37 Anomalous left coronary artery. Report of an unusual case with spontaneous remission of symptoms. Br Heart J 1973 0.79
38 Chronic treatment with the uncompetitive NMDA receptor antagonist memantine influences the polyamine and glycine binding sites of the NMDA receptor complex in aged rats. J Neural Transm Park Dis Dement Sect 1995 0.78
39 Brain distribution of an uncompetitive NMDA receptor antagonist; comparison to its in vitro potency in electrophysiological studies. Naunyn Schmiedebergs Arch Pharmacol 1999 0.78
40 Zinc changes AMPA receptor properties: results of binding studies and patch clamp recordings. Neuropharmacology 1996 0.77
41 The fraction of activated N-methyl-D-aspartate receptors during synaptic transmission remains constant in the presence of the glutamate release inhibitor riluzole. J Neural Transm (Vienna) 2008 0.77
42 Orphenadrine is an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist: binding and patch clamp studies. J Neural Transm Gen Sect 1995 0.77
43 The in vivo relevance of the varied channel-blocking properties of uncompetitive NMDA antagonists: tests on spinal neurones. Neuropharmacology 2001 0.77
44 A novel class of amino-alkylcyclohexanes as uncompetitive, fast, voltage-dependent, N-methyl-D-aspartate (NMDA) receptor antagonists--in vitro characterization. J Neural Transm (Vienna) 2007 0.76
45 Traumatic Uraemia. Br Med J 1945 0.76
46 Do kappa opioids mimic sigma agonists as amino acid antagonists? Neuropharmacology 1986 0.76
47 Protection against post-ischaemic neuronal loss in gerbil hippocampal CA1 by glycineB and AMPA antagonists. Short communication. J Neural Transm (Vienna) 1997 0.76
48 The Treatment of Acute Leukaemia in Adults with Cyclophosphamide. Postgrad Med J 1965 0.75
49 Congenital mitral stenosis. Br Heart J 1967 0.75
50 Transposition of the great arteries. A review of 37 cases after Mustard's operation. Thorax 1973 0.75
51 GlycineB recognition site of NMDA receptors and its antagonists. Amino Acids 1998 0.75
52 Local opioid receptors mediating antinociception in inflammation: endogenous ligands. Prog Clin Biol Res 1990 0.75
53 Reflex Action During General Surgical Anaesthesia. Ann Surg 1913 0.75
54 Fluorine-18 radiolabelling, biodistribution studies and preliminary PET evaluation of a new memantine derivative for imaging the NMDA receptor. J Recept Signal Transduct Res 1999 0.75
55 Preparation for retirement. Practitioner 1978 0.75
56 Mrz 2/579, a fast kinetic NMDA channel blocker, reduces the development of morphine tolerance in awake rats. Pain 2001 0.75
57 A novel series of 2-carboxytetrahydroquinolines provides new insights into the eastern region of glycine site NMDA antagonists. Arch Pharm (Weinheim) 2000 0.75
58 Stomatitis in Childhood. Arch Dis Child 1940 0.75
59 Twelve years follow-up after surgical correction of Fallot's tetralogy in childhood. Br Heart J 1972 0.75