T cell vaccination therapy in an induced model of anti-RNP autoimmune glomerulonephritis.

PubWeight™: 0.81‹?›

🔗 View Article (PMC 2950256)

Published in Clin Immunol on August 24, 2010

Authors

Sapna Trivedi1, YunJuan Zang, Schartess Culpepper, Erica Rosenbaum, Irina Fernandez, Laisel Martinez, Robert W Hoffman, Eric L Greidinger

Author Affiliations

1: University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

Articles cited by this

Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease. Arthritis Rheum (2005) 4.84

Functional assay of type I interferon in systemic lupus erythematosus plasma and association with anti-RNA binding protein autoantibodies. Arthritis Rheum (2006) 3.33

Association of antibodies to ribonucleoprotein and Sm antigens with mixed connective-tissue disease, systematic lupus erythematosus and other rheumatic diseases. N Engl J Med (1976) 3.22

Short term administration of costimulatory blockade and cyclophosphamide induces remission of systemic lupus erythematosus nephritis in NZB/W F1 mice by a mechanism downstream of renal immune complex deposition. J Immunol (2003) 1.74

B cell depletion therapy in systemic lupus erythematosus: relationships among serum B lymphocyte stimulator levels, autoantibody profile and clinical response. Ann Rheum Dis (2007) 1.62

Vaccination with selected synovial T cells in rheumatoid arthritis. Arthritis Rheum (2007) 1.53

Spliceosomal peptide P140 for immunotherapy of systemic lupus erythematosus: results of an early phase II clinical trial. Arthritis Rheum (2008) 1.17

Changes in anti-U1 RNA antibody levels correlate with disease activity in patients with systemic lupus erythematosus overlap syndrome. Arthritis Rheum (1992) 1.04

Apoptotic U1-70 kd is antigenically distinct from the intact form of the U1-70-kd molecule. Arthritis Rheum (2002) 1.03

A murine model of mixed connective tissue disease induced with U1 small nuclear RNP autoantigen. Arthritis Rheum (2006) 1.00

Treatment of lupus nephritis in adult (NZB + NZW)F1 mice by cortisone-facilitated tolerance to nucleic acid antigens. J Clin Invest (1978) 0.99

T cell immunity in connective tissue disease patients targets the RNA binding domain of the U1-70kDa small nuclear ribonucleoprotein. J Immunol (2002) 0.98

Structural analysis of TCRalpha and beta chains from human T-Cell clones specific for small nuclear ribonucleoprotein polypeptides Sm-D, Sm-B and U1-70 kDa: TCR complementarity determining region 3 usage appears highly conserved. Scand J Immunol (2001) 0.90

Human T cell clones specific for heterogeneous nuclear ribonucleoprotein A2 autoantigen from connective tissue disease patients assist in autoantibody production. Arthritis Rheum (2004) 0.89

CD4+ T cells target epitopes residing within the RNA-binding domain of the U1-70-kDa small nuclear ribonucleoprotein autoantigen and have restricted TCR diversity in an HLA-DR4-transgenic murine model of mixed connective tissue disease. J Immunol (2008) 0.85

Cloned human TCR from patients with autoimmune disease can respond to two structurally distinct autoantigens. J Immunol (2004) 0.85

Vaccination with autoreactive CD4(+)Th1 clones in lupus-prone MRL/Mp-Fas(lpr/lpr) mice. J Autoimmun (2009) 0.84

Tissue targeting of anti-RNP autoimmunity: effects of T cells and myeloid dendritic cells in a murine model. Arthritis Rheum (2009) 0.83

Murine chronic graft-versus-host disease as a model of systemic lupus erythematosus: effect of immunosuppressive drugs on disease development. Clin Exp Immunol (1989) 0.80

Articles by these authors

Ultraviolet radiation damages self noncoding RNA and is detected by TLR3. Nat Med (2012) 1.68

IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis. J Allergy Clin Immunol (2012) 1.46

Recent advances and opportunities in research on lupus: environmental influences and mechanisms of disease. Environ Health Perspect (2008) 1.17

An injectable synthetic immune-priming center mediates efficient T-cell class switching and T-helper 1 response against B cell lymphoma. J Control Release (2011) 1.07

U1 RNA induces innate immunity signaling. Arthritis Rheum (2004) 1.07

Apoptotic U1-70 kd is antigenically distinct from the intact form of the U1-70-kd molecule. Arthritis Rheum (2002) 1.03

A murine model of mixed connective tissue disease induced with U1 small nuclear RNP autoantigen. Arthritis Rheum (2006) 1.00

T cell immunity in connective tissue disease patients targets the RNA binding domain of the U1-70kDa small nuclear ribonucleoprotein. J Immunol (2002) 0.98

Tastants evoke cAMP signal in taste buds that is independent of calcium signaling. Am J Physiol Cell Physiol (2006) 0.97

A genome-wide study of lupus: preliminary analysis and data release. Ann N Y Acad Sci (2007) 0.92

Unique differentiation profile of mouse embryonic stem cells in rotary and stirred tank bioreactors. Tissue Eng Part A (2010) 0.90

A major B cell epitope present on the apoptotic but not the intact form of the U1-70-kDa ribonucleoprotein autoantigen. J Immunol (2004) 0.90

Regulation of phototransduction responsiveness and retinal degeneration by a phospholipase D-generated signaling lipid. J Cell Biol (2005) 0.90

Human Y-chromosome haplotyping by allele-specific polymerase chain reaction. Electrophoresis (2008) 0.89

Human T cell clones specific for heterogeneous nuclear ribonucleoprotein A2 autoantigen from connective tissue disease patients assist in autoantibody production. Arthritis Rheum (2004) 0.89

Circulating 20S proteasome levels in patients with mixed connective tissue disease and systemic lupus erythematosus. Clin Vaccine Immunol (2008) 0.89

Differential tissue targeting of autoimmunity manifestations by autoantigen-associated Y RNAs. Arthritis Rheum (2007) 0.88

Anti-ribonucleoprotein antibodies mediate enhanced lung injury following mesenteric ischemia/reperfusion in Rag-1(-/-) mice. Autoimmunity (2007) 0.86

Cloned human TCR from patients with autoimmune disease can respond to two structurally distinct autoantigens. J Immunol (2004) 0.85

CD4+ T cells target epitopes residing within the RNA-binding domain of the U1-70-kDa small nuclear ribonucleoprotein autoantigen and have restricted TCR diversity in an HLA-DR4-transgenic murine model of mixed connective tissue disease. J Immunol (2008) 0.85

Analysis of the horse V(H) repertoire and comparison with the human IGHV germline genes, and sheep, cattle and pig V(H) sequences. Mol Immunol (2005) 0.85

Macrophage-derived IL-18 and increased fibrinogen deposition are age-related inflammatory signatures of vascular remodeling. Am J Physiol Heart Circ Physiol (2014) 0.85

Clinical and immunologic manifestations of mixed connective tissue disease in a Miami population compared to a Midwestern US Caucasian population. J Rheumatol (2008) 0.85

Tissue targeting of anti-RNP autoimmunity: effects of T cells and myeloid dendritic cells in a murine model. Arthritis Rheum (2009) 0.83

Sicca symptoms and anti-SSA/Ro antibodies are common in mixed connective tissue disease. J Rheumatol (2002) 0.83

Development of feeder-free culture systems for generation of ckit+sca1+ progenitors from mouse iPS cells. Stem Cell Rev (2011) 0.82

Endosomal Toll-like receptors in autoimmunity: mechanisms for clinical diversity. Therapy (2009) 0.82

Characterization of TLR4-mediated auto-antibody production in a mouse model of histidyl-tRNA synthetase-induced myositis. Innate Immun (2012) 0.81

Autoantibodies in the pathogenesis of mixed connective tissue disease. Rheum Dis Clin North Am (2005) 0.81

A Rasch analysis for classification of systemic lupus erythematosus and mixed connective tissue disease. J Appl Meas (2008) 0.81

Two problematic human polymorphic Alu insertions. Electrophoresis (2003) 0.78

Polymorphic Alu insertions and genetic diversity among African populations. Hum Biol (2005) 0.77

Patients with antibodies to both PmScl and dsDNA. J Rheumatol (2004) 0.76

Conservation of pathogenic TCR homology across class II restrictions in anti-ribonucleoprotein autoimmunity: extended efficacy of T cell vaccine therapy. J Immunol (2014) 0.75

Epitope spreading in systemic lupus erythematosus: comment on the article by Monneaux and Muller. Arthritis Rheum (2003) 0.75

T cells and the loss of immunologic tolerance in Sjögren's syndrome and systemic lupus erythematosus. Arthritis Rheum (2007) 0.75