Published in J Neurochem on February 01, 2011
Peptide derived from HIV-1 TAT protein destabilizes a monolayer of endothelial cells in an in vitro model of the blood-brain barrier and allows permeation of high molecular weight proteins. J Biol Chem (2012) 0.85
Roles of the cellular prion protein in the regulation of cell-cell junctions and barrier function. Tissue Barriers (2013) 0.82
Combined local blood-brain barrier opening and systemic methotrexate for the treatment of brain tumors. J Cereb Blood Flow Metab (2015) 0.75
Characterisation of radioiodinated flavonoid derivatives for SPECT imaging of cerebral prion deposits. Sci Rep (2015) 0.75
Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein. Proc Natl Acad Sci U S A (2010) 2.86
Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis. J Exp Med (2003) 2.37
Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes. Proc Natl Acad Sci U S A (2002) 2.35
A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis. Science (2009) 2.30
Glutathionylation of human thioredoxin: a possible crosstalk between the glutathione and thioredoxin systems. Proc Natl Acad Sci U S A (2002) 2.00
Structural organization of the tight junctions. Biochim Biophys Acta (2007) 1.70
TCR activation eliminates glutamate receptor GluR3 from the cell surface of normal human T cells, via an autocrine/paracrine granzyme B-mediated proteolytic cleavage. J Immunol (2007) 1.58
Mutant prion protein expression is associated with an alteration of the Rab GDP dissociation inhibitor alpha (GDI)/Rab11 pathway. Mol Cell Proteomics (2009) 1.52
Increased DC trafficking to lymph nodes and contact hypersensitivity in junctional adhesion molecule-A-deficient mice. J Clin Invest (2004) 1.47
Tetracyclines affect prion infectivity. Proc Natl Acad Sci U S A (2002) 1.39
Blood-mediated scavenging of cerebrospinal fluid glutamate. J Neurochem (2003) 1.33
Protein nitration in a mouse model of familial amyotrophic lateral sclerosis: possible multifunctional role in the pathogenesis. J Biol Chem (2005) 1.26
Insoluble mutant SOD1 is partly oligoubiquitinated in amyotrophic lateral sclerosis mice. J Biol Chem (2006) 1.26
Synthesis and pharmacological evaluation of potent and highly selective D3 receptor ligands: inhibition of cocaine-seeking behavior and the role of dopamine D3/D2 receptors. J Med Chem (2003) 1.24
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole derivatives as potent and selective 5-HT1A serotonin receptor ligands. J Med Chem (2008) 1.23
Squalestatin cures prion-infected neurons and protects against prion neurotoxicity. J Biol Chem (2004) 1.19
Neuropathology of the recessive A673V APP mutation: Alzheimer disease with distinctive features. Acta Neuropathol (2010) 1.16
Neuroprotection with the CXCL8 inhibitor repertaxin in transient brain ischemia. Cytokine (2005) 1.15
The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide. J Neurochem (2009) 1.15
Closing the gap between the in-vivo and in-vitro blood-brain barrier tightness. Brain Res (2009) 1.13
Characterization of detergent-insoluble proteins in ALS indicates a causal link between nitrative stress and aggregation in pathogenesis. PLoS One (2009) 1.10
Lipid-based nanoparticles with high binding affinity for amyloid-beta1-42 peptide. Biomaterials (2010) 1.06
Brain neuroprotection by scavenging blood glutamate. Exp Neurol (2006) 1.06
Misplaced NMDA receptors in epileptogenesis contribute to excitotoxicity. Neurobiol Dis (2011) 1.04
Contribution of JAM-1 to epithelial differentiation and tight-junction biogenesis in the mouse preimplantation embryo. J Cell Sci (2004) 1.01
JNK regulates APP cleavage and degradation in a model of Alzheimer's disease. Neurobiol Dis (2009) 1.00
Synthesis and binding properties of novel selective 5-HT3 receptor ligands. Bioorg Med Chem (2004) 1.00
Longitudinal amyloid imaging in mouse brain with 11C-PIB: comparison of APP23, Tg2576, and APPswe-PS1dE9 mouse models of Alzheimer disease. J Nucl Med (2013) 1.00
Proteomic analysis of spinal cord of presymptomatic amyotrophic lateral sclerosis G93A SOD1 mouse. Biochem Biophys Res Commun (2006) 0.99
Specific recognition of biologically active amyloid-β oligomers by a new surface plasmon resonance-based immunoassay and an in vivo assay in Caenorhabditis elegans. J Biol Chem (2012) 0.97
Functionalization with ApoE-derived peptides enhances the interaction with brain capillary endothelial cells of nanoliposomes binding amyloid-beta peptide. J Biotechnol (2011) 0.96
Expression of mutant or cytosolic PrP in transgenic mice and cells is not associated with endoplasmic reticulum stress or proteasome dysfunction. PLoS One (2011) 0.96
Tetracycline and its analogues protect Caenorhabditis elegans from β amyloid-induced toxicity by targeting oligomers. Neurobiol Dis (2010) 0.96
The efficacy of tetracyclines in peripheral and intracerebral prion infection. PLoS One (2008) 0.96
Effect of tetracyclines on the dynamics of formation and destructuration of beta2-microglobulin amyloid fibrils. J Biol Chem (2010) 0.96
Mechanisms of glutamate efflux at the blood-brain barrier: involvement of glial cells. J Cereb Blood Flow Metab (2011) 0.96
The contribution of the blood glutamate scavenging activity of pyruvate to its neuroprotective properties in a rat model of closed head injury. Neurochem Res (2007) 0.95
Conformational plasticity of the Gerstmann-Sträussler-Scheinker disease peptide as indicated by its multiple aggregation pathways. J Mol Biol (2008) 0.95
The neurotoxicity of prion protein (PrP) peptide 106-126 is independent of the expression level of PrP and is not mediated by abnormal PrP species. Mol Cell Neurosci (2005) 0.94
The neuroprotective effects of oxaloacetate in closed head injury in rats is mediated by its blood glutamate scavenging activity: evidence from the use of maleate. J Neurosurg Anesthesiol (2009) 0.93
Oxaloacetate decreases the infarct size and attenuates the reduction in evoked responses after photothrombotic focal ischemia in the rat cortex. Cell Mol Neurobiol (2009) 0.93
Effect of glutamate and blood glutamate scavengers oxaloacetate and pyruvate on neurological outcome and pathohistology of the hippocampus after traumatic brain injury in rats. Anesthesiology (2012) 0.93
The role of platelet activating factor in prion and amyloid-beta neurotoxicity. Neuroreport (2004) 0.93
Curcumin-decorated nanoliposomes with very high affinity for amyloid-β1-42 peptide. Biomaterials (2010) 0.92
Functionalization of liposomes with ApoE-derived peptides at different density affects cellular uptake and drug transport across a blood-brain barrier model. Nanomedicine (2011) 0.92
Amyotrophic lateral sclerosis multiprotein biomarkers in peripheral blood mononuclear cells. PLoS One (2011) 0.92
Cell-free DNA as a marker for prediction of brain damage in traumatic brain injury in rats. J Neurotrauma (2011) 0.92
In vivo fate of avidin-nucleic acid nanoassemblies as multifunctional diagnostic tools. ACS Nano (2013) 0.92
Glial cells drive preconditioning-induced blood-brain barrier protection. Stroke (2011) 0.91
Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas. Invest New Drugs (2012) 0.91
Soluble Aβ oligomer-induced synaptopathy: c-Jun N-terminal kinase's role. J Mol Cell Biol (2013) 0.90
Use of surface plasmon resonance to study the elongation kinetics and the binding properties of the highly amyloidogenic Aβ(1-42) peptide, synthesized by depsi-peptide technique. Biosens Bioelectron (2010) 0.88
The effects of estrogen and progesterone on blood glutamate levels: evidence from changes of blood glutamate levels during the menstrual cycle in women. Biol Reprod (2010) 0.88
The protein interaction network of the epithelial junctional complex: a system-level analysis. Mol Biol Cell (2008) 0.88
Overcoming synthetic Abeta peptide aging: a new approach to an age-old problem. Amyloid (2009) 0.88
The molecular assembly of amyloid aβ controls its neurotoxicity and binding to cellular proteins. PLoS One (2011) 0.88
Oleuropein aglycone protects transgenic C. elegans strains expressing Aβ42 by reducing plaque load and motor deficit. PLoS One (2013) 0.88
β2 adrenergic-mediated reduction of blood glutamate levels and improved neurological outcome after traumatic brain injury in rats. J Neurosurg Anesthesiol (2012) 0.88
The aldehyde oxidase gene cluster in mice and rats. Aldehyde oxidase homologue 3, a novel member of the molybdo-flavoenzyme family with selective expression in the olfactory mucosa. J Biol Chem (2004) 0.87
Autoimmune epilepsy: distinct subpopulations of epilepsy patients harbor serum autoantibodies to either glutamate/AMPA receptor GluR3, glutamate/NMDA receptor subunit NR2A or double-stranded DNA. Epilepsy Res (2005) 0.87
A modified protocol to prepare seed-free starting solutions of amyloid-β (Aβ)₁₋₄₀ and Aβ₁₋₄₂ from the corresponding depsipeptides. Anal Biochem (2010) 0.87
Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinolinecarboxylic acid derivatives. Med Chem (2008) 0.87
Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors: design, synthesis, and effects on behavior. J Med Chem (2009) 0.87
A new face for old antibiotics: tetracyclines in treatment of amyloidoses. J Med Chem (2013) 0.86
Novel approaches for studying amyloidogenic peptides/proteins. Curr Opin Pharmacol (2013) 0.86
Tetracyclines and prion infectivity. Infect Disord Drug Targets (2009) 0.86
Cytoplasmic domain of human myelin protein zero likely folded as beta-structure in compact myelin. Biophys J (2006) 0.86
Blood-brain barrier alterations in the cerebral cortex in experimental autoimmune encephalomyelitis. J Neuropathol Exp Neurol (2012) 0.86
Tetracycline and its analogues as inhibitors of amyloid fibrils: searching for a geometrical pharmacophore by theoretical investigation of their conformational behavior in aqueous solution. J Mol Model (2004) 0.86
Conformational polymorphism of the PrP106-126 peptide in different environments: a molecular dynamics study. J Phys Chem B (2006) 0.85
Longitudinal tracking of human fetal cells labeled with super paramagnetic iron oxide nanoparticles in the brain of mice with motor neuron disease. PLoS One (2012) 0.85
Gerstmann-Sträussler-Scheinker disease amyloid protein polymerizes according to the "dock-and-lock" model. J Biol Chem (2005) 0.85
Peptide derived from HIV-1 TAT protein destabilizes a monolayer of endothelial cells in an in vitro model of the blood-brain barrier and allows permeation of high molecular weight proteins. J Biol Chem (2012) 0.85
Neurofilament-light increases the cell surface expression of the N-methyl-D-aspartate receptor and prevents its ubiquitination. J Neurochem (2005) 0.85
Intrastriatal administration of sigma ligands inhibits basal dopamine release in vivo. Neuropharmacology (2003) 0.85
Lack of caspase-dependent apoptosis in spinal motor neurons of the wobbler mouse. Neurosci Lett (2007) 0.85
Pyruvate's blood glutamate scavenging activity contributes to the spectrum of its neuroprotective mechanisms in a rat model of stroke. Eur J Neurosci (2011) 0.85
Good gene, bad gene: new APP variant may be both. Prog Neurobiol (2012) 0.84
Neural precursor-derived astrocytes of wobbler mice induce apoptotic death of motor neurons through reduced glutamate uptake. Exp Neurol (2010) 0.84
Analysis of the cerebellar proteome in a transgenic mouse model of inherited prion disease reveals preclinical alteration of calcineurin activity. Proteomics (2006) 0.84
Junctional adhesion molecule-A regulates cell migration and resistance to shear stress. J Cell Physiol (2006) 0.84
Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents. J Med Chem (2004) 0.84
Oxaloacetate restores the long-term potentiation impaired in rat hippocampus CA1 region by 2-vessel occlusion. Eur J Pharmacol (2008) 0.83
A new fluorogenic peptide determines proteasome activity in single cells. J Med Chem (2010) 0.83
Different mutations at V363 MAPT codon are associated with atypical clinical phenotypes and show unusual structural and functional features. Neurobiol Aging (2013) 0.83
Novel sigma receptor ligands: synthesis and biological profile. J Med Chem (2007) 0.83
Cell-free DNA--a marker to predict ischemic brain damage in a rat stroke experimental model. J Neurosurg Anesthesiol (2011) 0.83
Redox regulation of cyclophilin A by glutathionylation. Proteomics (2006) 0.83
Ginkgolide B inhibits the neurotoxicity of prions or amyloid-beta1-42. J Neuroinflammation (2004) 0.83
Galpha13 mediates activation of the cytosolic phospholipase A2alpha through fine regulation of ERK phosphorylation. Cell Signal (2006) 0.83
Morphological and neuro-behavioral parallels in the rat model of stroke. Behav Brain Res (2011) 0.83
Docosahexaenoic and eicosapentaenoic acids increase neuronal death in response to HuPrP82-146 and Abeta 1-42. Neuropharmacology (2008) 0.83
Neurotoxic and gliotrophic activity of a synthetic peptide homologous to Gerstmann-Sträussler-Scheinker disease amyloid protein. J Neurosci (2007) 0.83