PubRank

Roel Goldschmeding

Author PubWeight™ 90.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair. Nat Genet 2012 2.74
2 Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy? Matrix Biol 2002 2.45
3 Protein restriction in lactation confers nephroprotective effects in the male rat and is associated with increased antioxidant expression. Am J Physiol Regul Integr Comp Physiol 2007 2.15
4 CTGF expression in mesangial cells: involvement of SMADs, MAP kinase, and PKC. Kidney Int 2002 1.77
5 Treatment with cyclophosphamide delays the progression of chronic lesions more effectively than does treatment with azathioprine plus methylprednisolone in patients with proliferative lupus nephritis. Arthritis Rheum 2007 1.69
6 The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy. PLoS One 2008 1.68
7 Gain of glycosylation in integrin α3 causes lung disease and nephrotic syndrome. J Clin Invest 2012 1.66
8 Circulating growth differentiation factor-15 correlates with myocardial fibrosis in patients with non-ischaemic dilated cardiomyopathy and decreases rapidly after left ventricular assist device support. Eur J Heart Fail 2012 1.64
9 Reduction of urinary connective tissue growth factor by Losartan in type 1 patients with diabetic nephropathy. Kidney Int 2005 1.52
10 Fibrin-thrombin coated sealant increases strength of esophagogastric anastomoses in a rat model. J Surg Res 2012 1.43
11 A shift in the balance of vascular endothelial growth factor and connective tissue growth factor by bevacizumab causes the angiofibrotic switch in proliferative diabetic retinopathy. Br J Ophthalmol 2012 1.33
12 Induction of renal fibrotic genes by TGF-β1 requires EGFR activation, p53 and reactive oxygen species. Cell Signal 2013 1.29
13 Bone-marrow-derived cells contribute to glomerular endothelial repair in experimental glomerulonephritis. Am J Pathol 2003 1.28
14 Urinary connective tissue growth factor excretion correlates with clinical markers of renal disease in a large population of type 1 diabetic patients with diabetic nephropathy. Diabetes Care 2006 1.20
15 In mice, proteinuria and renal inflammatory responses to albumin overload are strain-dependent. Nephrol Dial Transplant 2005 1.20
16 CTGF inhibits BMP-7 signaling in diabetic nephropathy. J Am Soc Nephrol 2008 1.19
17 Plasma connective tissue growth factor is an independent predictor of end-stage renal disease and mortality in type 1 diabetic nephropathy. Diabetes Care 2008 1.18
18 Association of connective tissue growth factor with fibrosis in vitreoretinal disorders in the human eye. Arch Ophthalmol 2006 1.18
19 Connective tissue growth factor and igf-I are produced by human renal fibroblasts and cooperate in the induction of collagen production by high glucose. Diabetes 2003 1.16
20 Interobserver agreement of scoring of histopathological characteristics and classification of lupus nephritis. Nephrol Dial Transplant 2007 1.13
21 Fidelity and evolution of recurrent FSGS in renal allografts. J Am Soc Nephrol 2008 1.11
22 Effect of VEGF-A on expression of profibrotic growth factor and extracellular matrix genes in the retina. Invest Ophthalmol Vis Sci 2007 1.10
23 Oxidative stress in obstructive nephropathy. Int J Exp Pathol 2010 1.10
24 Angiogenesis is not impaired in connective tissue growth factor (CTGF) knock-out mice. J Histochem Cytochem 2007 1.10
25 Loss of the BMP antagonist USAG-1 ameliorates disease in a mouse model of the progressive hereditary kidney disease Alport syndrome. J Clin Invest 2010 1.09
26 Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction. Dev Dyn 2004 1.08
27 Bone morphogenetic protein-7 and connective tissue growth factor: novel targets for treatment of renal fibrosis? Pharm Res 2008 1.07
28 Temporal expression profile and distribution pattern indicate a role of connective tissue growth factor (CTGF/CCN-2) in diabetic nephropathy in mice. Am J Physiol Renal Physiol 2005 1.06
29 Connective tissue growth factor is increased in plasma of type 1 diabetic patients with nephropathy. Diabetes Care 2004 1.05
30 BMP signaling and podocyte markers are decreased in human diabetic nephropathy in association with CTGF overexpression. J Histochem Cytochem 2009 1.04
31 Loss of endogenous bone morphogenetic protein-6 aggravates renal fibrosis. Am J Pathol 2011 1.03
32 CTGF/CCN-2 over-expression can directly induce features of skeletal muscle dystrophy. J Pathol 2011 1.02
33 Perinatal L-arginine and antioxidant supplements reduce adult blood pressure in spontaneously hypertensive rats. Hypertension 2004 1.02
34 Targeting podocyte-associated diseases. Adv Drug Deliv Rev 2010 1.01
35 Target organ cross talk in cardiorenal syndrome: animal models. Am J Physiol Renal Physiol 2012 0.99
36 Reduced Cx43 expression triggers increased fibrosis due to enhanced fibroblast activity. Circ Arrhythm Electrophysiol 2012 0.98
37 Bone-marrow-derived cells contribute to endothelial repair after thrombotic microangiopathy. Blood 2002 0.97
38 Allelic depletion of grem1 attenuates diabetic kidney disease. Diabetes 2009 0.97
39 Connective tissue growth factor (CTGF/CCN2) is increased in peritoneal dialysis patients with high peritoneal solute transport rate. Am J Physiol Renal Physiol 2009 0.97
40 Healthy bone marrow cells reduce progression of kidney failure better than CKD bone marrow cells in rats with established chronic kidney disease. Cell Transplant 2012 0.97
41 Connective tissue growth factor (CTGF/CCN2) ELISA: a novel tool for monitoring fibrosis. Biomarkers 2011 0.97
42 Lipoxin A₄ and benzo-lipoxin A₄ attenuate experimental renal fibrosis. FASEB J 2011 0.96
43 Connective tissue growth factor is necessary for retinal capillary basal lamina thickening in diabetic mice. J Histochem Cytochem 2008 0.95
44 Differential regulation of E-cadherin and alpha-smooth muscle actin by BMP 7 in human renal proximal tubule epithelial cells and its implication in renal fibrosis. Am J Physiol Renal Physiol 2009 0.92
45 Imbalance of growth factor signalling in diabetic kidney disease: is connective tissue growth factor (CTGF, CCN2) the perfect intervention point? Nephrol Dial Transplant 2004 0.91
46 A perinatal nitric oxide donor increases renal vascular resistance and ameliorates hypertension and glomerular injury in adult fawn-hooded hypertensive rats. Am J Physiol Regul Integr Comp Physiol 2008 0.91
47 Renal proximal tubular dysfunction is a major determinant of urinary connective tissue growth factor excretion. Am J Physiol Renal Physiol 2010 0.90
48 Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy. Hum Mol Genet 2013 0.90
49 Could aging human skin use a connective tissue growth factor boost to increase collagen content? J Invest Dermatol 2010 0.88
50 Hypercholesterolemia in rats induces podocyte stress and decreases renal cortical nitric oxide synthesis via an angiotensin II type 1 receptor-sensitive mechanism. J Am Soc Nephrol 2004 0.88
51 Direct visualization of Smad1/5/8-mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys. J Pathol 2011 0.87
52 Nitric oxide down-regulates connective tissue growth factor in rat mesangial cells. Kidney Int 2002 0.87
53 Proteinuria is preceded by decreased nitric oxide synthesis and prevented by a NO donor in cholesterol-fed rats. Kidney Int 2002 0.86
54 Hemizygous deletion of CTGF/CCN2 does not suffice to prevent fibrosis of the severely injured kidney. Matrix Biol 2012 0.85
55 Male gender increases sensitivity to renal injury in response to cholesterol loading. Am J Physiol Renal Physiol 2002 0.84
56 Deletion of Irs2 causes reduced kidney size in mice: role for inhibition of GSK3beta? BMC Dev Biol 2010 0.84
57 The nitric oxide donor molsidomine rescues cardiac function in rats with chronic kidney disease and cardiac dysfunction. Am J Physiol Heart Circ Physiol 2010 0.83
58 Perinatal micronutrient supplements ameliorate hypertension and proteinuria in adult fawn-hooded hypertensive rats. Am J Hypertens 2010 0.83
59 Minimal coronary artery damage by myocardial electroporation ablation. Europace 2012 0.82
60 Temporary losartan or captopril in young SHR induces malignant hypertension despite initial normotension. Kidney Int 2004 0.82
61 Expression patterns of connective tissue growth factor and of TGF-beta isoforms during glomerular injury recapitulate glomerulogenesis. Am J Physiol Renal Physiol 2010 0.82
62 Modulation of TGF-β/BMP-6 expression and increased levels of circulating smooth muscle progenitor cells in a type I diabetes mouse model. Cardiovasc Diabetol 2010 0.82
63 Met-RANTES reduces endothelial progenitor cell homing to activated (glomerular) endothelium in vitro and in vivo. Am J Physiol Renal Physiol 2007 0.81
64 Activated vitronectin as a target for anticancer therapy with human antibodies. Cancer Immunol Immunother 2004 0.81
65 Subtotal nephrectomy plus coronary ligation leads to more pronounced damage in both organs than either nephrectomy or coronary ligation. Am J Physiol Heart Circ Physiol 2011 0.81
66 Effects of antiproteinuric intervention on elevated connective tissue growth factor (CTGF/CCN-2) plasma and urine levels in nondiabetic nephropathy. Clin J Am Soc Nephrol 2011 0.81
67 Connective tissue growth factor is associated with a stable atherosclerotic plaque phenotype and is involved in plaque stabilization after stroke. Stroke 2010 0.80
68 Vitreous TIMP-1 levels associate with neovascularization and TGF-β2 levels but not with fibrosis in the clinical course of proliferative diabetic retinopathy. J Cell Commun Signal 2012 0.79
69 The CTGF -945GC polymorphism is not associated with plasma CTGF and does not predict nephropathy or outcome in type 1 diabetes. J Negat Results Biomed 2011 0.79
70 Neonatal dexamethasone treatment in the rat leads to kidney damage in adulthood. Pediatr Res 2010 0.78
71 A perspective on anti-CCN2 therapy for chronic kidney disease. Nephrol Dial Transplant 2014 0.78
72 CCN2/CTGF is required for matrix organization and to protect growth plate chondrocytes from cellular stress. J Cell Commun Signal 2013 0.78
73 Involvement of connective tissue growth factor in human and experimental hypertensive nephrosclerosis. Nephron Exp Nephrol 2010 0.78
74 Intervention in growth factor activated signaling pathways by renally targeted kinase inhibitors. J Control Release 2008 0.78
75 Effect of GFR on plasma N-terminal connective tissue growth factor (CTGF) concentrations. Am J Kidney Dis 2012 0.77
76 Urinary connective tissue growth factor is associated with human renal allograft fibrogenesis. Transplantation 2013 0.77
77 Compensatory growth of congenital solitary kidneys in pigs reflects increased nephron numbers rather than hypertrophy. PLoS One 2012 0.77
78 Histological assessment of pre-transplant kidney biopsies is reproducible and representative. Histopathology 2010 0.77
79 Amelioration of anti-Thy1-glomerulonephritis by PPAR-gamma agonism without increase of endothelial progenitor cell homing. Am J Physiol Renal Physiol 2007 0.77
80 The Dutch Transplantation in Vasculitis (DUTRAVAS) Study: Outcome of Renal Transplantation in Antineutrophil Cytoplasmic Antibody-associated Glomerulonephritis. Transplantation 2016 0.77
81 Kidney fibrosis: origins and interventions. Transplantation 2016 0.76
82 I-131 accumulation in a benign cystic mesothelioma in a patient with follicular thyroid cancer. Thyroid 2008 0.76
83 ACE Inhibition in Anti-Thy1 Glomerulonephritis Limits Proteinuria but Does Not Improve Renal Function and Structural Remodeling. Nephron Extra 2012 0.76
84 Visualizing tubular lipid peroxidation in intact renal tissue in hypertensive rats. J Am Soc Nephrol 2002 0.76
85 Reduction of cerebral injury in stroke-prone spontaneously hypertensive rats by amlodipine. Eur J Pharmacol 2002 0.76
86 Llama heavy-chain antibody fragments efficiently remove toxic shock syndrome toxin 1 from plasma in vitro but not in experimental porcine septic shock. Shock 2010 0.76
87 Distinct genetic subsets in ANCA-associated vasculitis. N Engl J Med 2012 0.75
88 Connective tissue growth factor is involved in structural retinal vascular changes in long-term experimental diabetes. J Histochem Cytochem 2013 0.75
89 Does high or low urinary connective tissue growth factor predict CKD? Am J Kidney Dis 2011 0.75
90 IgG4-related disease with atypical laryngeal presentation and Behçet/granulomatous polyangiitis mimicking features. BMJ Case Rep 2013 0.75
91 Nrf2 implicated as a novel therapeutic target for renal regeneration after acute kidney injury. Nephrol Dial Transplant 2013 0.75
92 Headache and a syndrome of bilateral hydronephrosis. Nephrol Dial Transplant 2002 0.75
93 A dry mouth and oedematous ankle. Nephrol Dial Transplant 2006 0.75