Published in J Neurotrauma on October 20, 2010
Large-scale chondroitin sulfate proteoglycan digestion with chondroitinase gene therapy leads to reduced pathology and modulates macrophage phenotype following spinal cord contusion injury. J Neurosci (2014) 1.05
Mammalian target of rapamycin's distinct roles and effectiveness in promoting compensatory axonal sprouting in the injured CNS. J Neurosci (2014) 0.98
Intracerebral chondroitinase ABC and heparan sulfate proteoglycan glypican improve outcome from chronic stroke in rats. Proc Natl Acad Sci U S A (2012) 0.98
Neurorestorative treatments for traumatic brain injury. Discov Med (2010) 0.94
Temporal dynamics of cerebral blood flow, cortical damage, apoptosis, astrocyte-vasculature interaction and astrogliosis in the pericontusional region after traumatic brain injury. Front Neurol (2014) 0.92
Erythropoietin promotes neurovascular remodeling and long-term functional recovery in rats following traumatic brain injury. Brain Res (2011) 0.84
The expression pattern of ADP-ribosyltransferase 3 in rat traumatic brain injury. J Mol Histol (2011) 0.82
Chondroitinase enhances cortical map plasticity and increases functionally active sprouting axons after brain injury. J Neurotrauma (2013) 0.81
Bi-directional changes in fractional anisotropy after experiment TBI: Disorganization and reorganization? Neuroimage (2016) 0.80
Cortical reorganization after experimental traumatic brain injury: a functional autoradiography study. J Neurotrauma (2013) 0.79
Chondroitin sulfate proteoglycans in the nervous system: inhibitors to repair. Biomed Res Int (2014) 0.79
Disconnection and hyper-connectivity underlie reorganization after TBI: A rodent functional connectomic analysis. Exp Neurol (2015) 0.79
Intraventricular hemorrhage induces deposition of proteoglycans in premature rabbits, but their in vivo degradation with chondroitinase does not restore myelination, ventricle size and neurological recovery. Exp Neurol (2013) 0.78
Translational spinal cord injury research: preclinical guidelines and challenges. Handb Clin Neurol (2012) 0.78
In the presence of danger: The extracellular matrix defensive response to central nervous system injury. Neural Regen Res (2014) 0.78
Chondroitinase ABC promotes functional recovery after spinal cord injury. Nature (2002) 8.22
Reactivation of ocular dominance plasticity in the adult visual cortex. Science (2002) 6.06
Combining an autologous peripheral nervous system "bridge" and matrix modification by chondroitinase allows robust, functional regeneration beyond a hemisection lesion of the adult rat spinal cord. J Neurosci (2006) 3.21
Nogo receptor antagonism promotes stroke recovery by enhancing axonal plasticity. J Neurosci (2004) 2.67
Chondroitinase ABC treatment opens a window of opportunity for task-specific rehabilitation. Nat Neurosci (2009) 2.37
Changes in distribution, cell associations, and protein expression levels of NG2, neurocan, phosphacan, brevican, versican V2, and tenascin-C during acute to chronic maturation of spinal cord scar tissue. J Neurosci Res (2003) 2.04
Chondroitinase ABC digestion of the perineuronal net promotes functional collateral sprouting in the cuneate nucleus after cervical spinal cord injury. J Neurosci (2006) 2.00
Regeneration of CNS axons back to their target following treatment of adult rat brain with chondroitinase ABC. Nat Neurosci (2001) 1.99
The "staircase test": a measure of independent forelimb reaching and grasping abilities in rats. J Neurosci Methods (1991) 1.93
Myelinated and unmyelinated axons of the corpus callosum differ in vulnerability and functional recovery following traumatic brain injury. Exp Neurol (2005) 1.67
Functional axonal regeneration through astrocytic scar genetically modified to digest chondroitin sulfate proteoglycans. J Neurosci (2007) 1.64
Animals lacking link protein have attenuated perineuronal nets and persistent plasticity. Brain (2010) 1.63
Synergistic effects of transplanted adult neural stem/progenitor cells, chondroitinase, and growth factors promote functional repair and plasticity of the chronically injured spinal cord. J Neurosci (2010) 1.59
Inosine promotes recovery of skilled motor function in a model of focal brain injury. Brain (2007) 1.57
Time course of cellular pathology after controlled cortical impact injury. Exp Neurol (2003) 1.55
Sustained delivery of thermostabilized chABC enhances axonal sprouting and functional recovery after spinal cord injury. Proc Natl Acad Sci U S A (2009) 1.48
Delayed treatment with monoclonal antibody IN-1 1 week after stroke results in recovery of function and corticorubral plasticity in adult rats. J Cereb Blood Flow Metab (2005) 1.48
Anti-Nogo-A antibody infusion 24 hours after experimental stroke improved behavioral outcome and corticospinal plasticity in normotensive and spontaneously hypertensive rats. J Cereb Blood Flow Metab (2003) 1.42
Versican is upregulated in CNS injury and is a product of oligodendrocyte lineage cells. J Neurosci (2002) 1.29
Chondroitinase ABC combined with neural stem/progenitor cell transplantation enhances graft cell migration and outgrowth of growth-associated protein-43-positive fibers after rat spinal cord injury. Eur J Neurosci (2005) 1.24
Synergistic effects of brain-derived neurotrophic factor and chondroitinase ABC on retinal fiber sprouting after denervation of the superior colliculus in adult rats. J Neurosci (2003) 1.13
Acute and long-lasting changes in extracellular-matrix chondroitin-sulphate proteoglycans induced by injection of chondroitinase ABC in the adult rat brain. Exp Brain Res (1998) 1.13
Degradation of chondroitin sulfate proteoglycans induces sprouting of intact purkinje axons in the cerebellum of the adult rat. J Neurosci (2005) 1.13
Chondroitinase ABC has a long-lasting effect on chondroitin sulphate glycosaminoglycan content in the injured rat brain. J Neurochem (2007) 1.06
Axonal regeneration of Clarke's neurons beyond the spinal cord injury scar after treatment with chondroitinase ABC. Exp Neurol (2003) 1.05
Pericontusion axon sprouting is spatially and temporally consistent with a growth-permissive environment after traumatic brain injury. J Neuropathol Exp Neurol (2010) 0.99
Attenuation of the electrophysiological function of the corpus callosum after fluid percussion injury in the rat. J Neurotrauma (2002) 0.98
Administration of chondroitinase ABC rostral or caudal to a spinal cord injury site promotes anatomical but not functional plasticity. J Neurotrauma (2009) 0.98
Characterization of a prolonged regenerative attempt by diffusely injured axons following traumatic brain injury in adult cat: a light and electron microscopic immunocytochemical study. Acta Neuropathol (1997) 0.93
Bilateral growth-related protein expression suggests a transient increase in regenerative potential following brain trauma. J Comp Neurol (2000) 0.93
Traumatic brain injury results in disparate regions of chondroitin sulfate proteoglycan expression that are temporally limited. J Neurosci Res (2009) 0.91
Traumatic brain injury in rats results in increased expression of Gap-43 that correlates with behavioral recovery. Neurosci Lett (1998) 0.91
Regeneration of lesioned entorhino-hippocampal axons in vitro by combined degradation of inhibitory proteoglycans and blockade of Nogo-66/NgR signaling. FASEB J (2006) 0.90
Changes in the amounts of chondroitin sulfate proteoglycans in rat brain after neonatal hypoxia-ischemia. J Neurosci Res (2005) 0.82
Clinical trials in head injury. J Neurotrauma (2002) 4.34
Metabolic crisis without brain ischemia is common after traumatic brain injury: a combined microdialysis and positron emission tomography study. J Cereb Blood Flow Metab (2005) 2.52
Lateral fluid percussion brain injury: a 15-year review and evaluation. J Neurotrauma (2005) 2.37
Repeated mild traumatic brain injury: mechanisms of cerebral vulnerability. J Neurotrauma (2013) 2.12
Persistent metabolic crisis as measured by elevated cerebral microdialysis lactate-pyruvate ratio predicts chronic frontal lobe brain atrophy after traumatic brain injury. Crit Care Med (2008) 2.00
NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans. Nat Neurosci (2012) 1.94
Persistently low extracellular glucose correlates with poor outcome 6 months after human traumatic brain injury despite a lack of increased lactate: a microdialysis study. J Cereb Blood Flow Metab (2003) 1.93
The molecular pathophysiology of concussive brain injury. Clin Sports Med (2011) 1.82
Pericontusional brain tissue exhibits persistent elevation of lactate/pyruvate ratio independent of cerebral perfusion pressure. Crit Care Med (2007) 1.72
Translational neurochemical research in acute human brain injury: the current status and potential future for cerebral microdialysis. J Neurotrauma (2005) 1.67
Efficacy of hyperventilation, blood pressure elevation, and metabolic suppression therapy in controlling intracranial pressure after head injury. J Neurosurg (2002) 1.67
Tight glycemic control increases metabolic distress in traumatic brain injury: a randomized controlled within-subjects trial. Crit Care Med (2012) 1.62
Neuroimaging of structural pathology and connectomics in traumatic brain injury: Toward personalized outcome prediction. Neuroimage Clin (2012) 1.52
Energy dysfunction as a predictor of outcome after moderate or severe head injury: indices of oxygen, glucose, and lactate metabolism. J Cereb Blood Flow Metab (2003) 1.42
Time window for voluntary exercise-induced increases in hippocampal neuroplasticity molecules after traumatic brain injury is severity dependent. J Neurotrauma (2007) 1.36
Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injury. J Neurotrauma (2005) 1.31
The new neurometabolic cascade of concussion. Neurosurgery (2014) 1.31
Mitochondrial damage and dysfunction in traumatic brain injury. Mitochondrion (2004) 1.30
Increased pentose phosphate pathway flux after clinical traumatic brain injury: a [1,2-13C2]glucose labeling study in humans. J Cereb Blood Flow Metab (2007) 1.28
Early nonischemic oxidative metabolic dysfunction leads to chronic brain atrophy in traumatic brain injury. J Cereb Blood Flow Metab (2009) 1.28
Experience-dependent behavioral plasticity is disturbed following traumatic injury to the immature brain. Behav Brain Res (2005) 1.20
Ontogeny of Rat Recognition Memory measured by the novel object recognition task. Dev Psychobiol (2009) 1.20
Increased hippocampal CA3 vulnerability to low-level kainic acid following lateral fluid percussion injury. J Neurotrauma (2003) 1.13
Accuracy of a method using short inhalation of (15)O-O(2) for measuring cerebral oxygen extraction fraction with PET in healthy humans. J Nucl Med (2004) 1.13
Developing experimental models to address traumatic brain injury in children. J Neurotrauma (2003) 1.11
Metabolic and histologic effects of sodium pyruvate treatment in the rat after cortical contusion injury. J Neurotrauma (2009) 1.10
Routine and quantitative EEG in mild traumatic brain injury. Clin Neurophysiol (2005) 1.10
N-methyl-D-aspartate receptor subunit changes after traumatic injury to the developing brain. J Neurotrauma (2006) 1.10
Patient-tailored connectomics visualization for the assessment of white matter atrophy in traumatic brain injury. Front Neurol (2012) 1.09
Selective metabolic reduction in gray matter acutely following human traumatic brain injury. J Neurotrauma (2004) 1.09
The fate of glucose during the period of decreased metabolism after fluid percussion injury: a 13C NMR study. J Neurotrauma (2007) 1.08
The effects of a ketogenic diet on behavioral outcome after controlled cortical impact injury in the juvenile and adult rat. J Neurotrauma (2009) 1.05
The effects of age and ketogenic diet on local cerebral metabolic rates of glucose after controlled cortical impact injury in rats. J Neurotrauma (2009) 1.04
Lateral fluid percussion injury in the developing rat causes an acute, mild behavioral dysfunction in the absence of significant cell death. Brain Res (2006) 1.03
Correlation of regional metabolic rates of glucose with glasgow coma scale after traumatic brain injury. J Nucl Med (2003) 1.01
Acute changes in regional cerebral (18)F-FDG kinetics in patients with traumatic brain injury. J Nucl Med (2004) 1.01
Pericontusion axon sprouting is spatially and temporally consistent with a growth-permissive environment after traumatic brain injury. J Neuropathol Exp Neurol (2010) 0.99
Comparison of acute and chronic traumatic brain injury using semi-automatic multimodal segmentation of MR volumes. J Neurotrauma (2011) 0.99
Glucose metabolism after traumatic brain injury: estimation of pyruvate carboxylase and pyruvate dehydrogenase flux by mass isotopomer analysis. J Neurotrauma (2007) 0.99
Genes preferentially induced by depolarization after concussive brain injury: effects of age and injury severity. J Neurotrauma (2002) 0.98
Concussive brain injury enhances fear learning and excitatory processes in the amygdala. Biol Psychiatry (2011) 0.98
Subcortical white matter metabolic changes remote from focal hemorrhagic lesions suggest diffuse injury after human traumatic brain injury. Neurosurgery (2004) 0.97
A pediatric perspective on concussion pathophysiology. Curr Opin Pediatr (2012) 0.97
Beneficial effects of sodium or ethyl pyruvate after traumatic brain injury in the rat. Exp Neurol (2010) 0.95
Differential gene expression in hippocampus following experimental brain trauma reveals distinct features of moderate and severe injuries. J Neurotrauma (2004) 0.93
Ketogenic diet prevents alterations in brain metabolism in young but not adult rats after traumatic brain injury. J Neurotrauma (2011) 0.92
Regional heterogeneity of post-traumatic brain metabolism as studied by microdialysis, magnetic resonance spectroscopy and positron emission tomography. Brain Pathol (2004) 0.92
Metabolic, neurochemical, and histologic responses to vibrissa motor cortex stimulation after traumatic brain injury. J Cereb Blood Flow Metab (2003) 0.92
Early and persistent impaired percent alpha variability on continuous electroencephalography monitoring as predictive of poor outcome after traumatic brain injury. J Neurosurg (2002) 0.90
Injury severity differentially affects short- and long-term neuroendocrine outcomes of traumatic brain injury. J Neurotrauma (2008) 0.89
Molecular and physiological responses to juvenile traumatic brain injury: focus on growth and metabolism. Dev Neurosci (2010) 0.88
The impact of substance abuse on mortality in patients with severe traumatic brain injury. J Trauma (2008) 0.88
Controlled contusion injury alters molecular systems associated with cognitive performance. J Neurosci Res (2009) 0.88
Redefining the pericontusional penumbra following traumatic brain injury: evidence of deteriorating metabolic derangements based on positron emission tomography. J Neurotrauma (2013) 0.87
Alcohol consumption in traumatic brain injury: attenuation of TBI-induced hyperthermia and neurocognitive deficits. J Neurotrauma (2002) 0.87
Temperature and heart rate responses to exercise following mild traumatic brain injury. J Neurotrauma (2013) 0.87
Astrocyte oxidative metabolism and metabolite trafficking after fluid percussion brain injury in adult rats. J Neurotrauma (2010) 0.86
Traumatic brain injury induced neuroprotection of retinal ganglion cells to optic nerve crush. J Neurotrauma (2006) 0.86
Early metabolic crisis-related brain atrophy and cognition in traumatic brain injury. Brain Imaging Behav (2013) 0.85
Delayed sodium pyruvate treatment improves working memory following experimental traumatic brain injury. Neurosci Lett (2011) 0.85
Restoration of cerebral vasoreactivity by an L-type calcium channel blocker following fluid percussion brain injury. J Neurotrauma (2005) 0.85
Paradoxical effects of cortical impact injury on environmentally enriched rats. J Neurotrauma (2004) 0.85
Preventing flow-metabolism uncoupling acutely reduces axonal injury after traumatic brain injury. J Neurotrauma (2012) 0.84
Insights into the metabolic response to traumatic brain injury as revealed by (13)C NMR spectroscopy. Front Neuroenergetics (2013) 0.84
Duration of ATP reduction affects extent of CA1 cell death in rat models of fluid percussion injury combined with secondary ischemia. Brain Res (2008) 0.83
Glucose administration after traumatic brain injury improves cerebral metabolism and reduces secondary neuronal injury. Brain Res (2013) 0.83
Potentially neuroprotective gene modulation in an in vitro model of mild traumatic brain injury. Mol Cell Biochem (2012) 0.83
Injury severity differentially alters sensitivity to dexamethasone after traumatic brain injury. J Neurotrauma (2010) 0.82
Chondroitinase enhances cortical map plasticity and increases functionally active sprouting axons after brain injury. J Neurotrauma (2013) 0.81
Measurement of the global lumped constant for 2-deoxy-2-[18F]fluoro-D-glucose in normal human brain using [15O]water and 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography imaging. A method with validation based on multiple methodologies. Mol Imaging Biol (2003) 0.81
Restoration of neuroendocrine stress response by glucocorticoid receptor or GABA(A) receptor antagonists after experimental traumatic brain injury. J Neurotrauma (2013) 0.79
The New Neurometabolic Cascade of Concussion. Neurosurgery (2014) 0.79
Recovery of stress response coincides with responsiveness to voluntary exercise after traumatic brain injury. J Neurotrauma (2013) 0.78
Care of war veterans with mild traumatic brain injury. N Engl J Med (2009) 0.78
Metabolomic analysis of cerebral spinal fluid from patients with severe brain injury. Acta Neurochir Suppl (2013) 0.77
Increased cerebral uptake of [18F]fluoro-deoxyglucose but not [1-14C]glucose early following traumatic brain injury in rats. J Neurotrauma (2009) 0.77
Adolescent TBI-induced hypopituitarism causes sexual dysfunction in adult male rats. Dev Neurobiol (2014) 0.76
The linear relationship between transcranial Doppler pulsatility indices and intracranial pressure is influenced by traumatic brain injury and vasospasm. Acta Neurochir Suppl (2012) 0.76
Oxidative need and oxidative capacity following traumatic brain injury. Crit Care Med (2007) 0.75
Subarachnoid hemorrhage induces dynamic changes in regional cerebral metabolism in rats. J Neurotrauma (2002) 0.75