Published in PLoS One on August 30, 2010
Sensitivity and specificity of serologic assays for detection of human infection with 2009 pandemic H1N1 virus in U.S. populations. J Clin Microbiol (2011) 1.62
Influenza infection rates, measurement errors and the interpretation of paired serology. PLoS Pathog (2012) 1.38
Differences in antibody responses of individuals with natural infection and those vaccinated against pandemic H1N1 2009 influenza. Clin Vaccine Immunol (2011) 1.37
The age-specific cumulative incidence of infection with pandemic influenza H1N1 2009 was similar in various countries prior to vaccination. PLoS One (2011) 1.23
Tools to detect influenza virus. Yonsei Med J (2013) 1.10
Serological response to the 2009 pandemic influenza A (H1N1) virus for disease diagnosis and estimating the infection rate in Thai population. PLoS One (2011) 1.02
Pandemic (H1N1) 2009 risk for frontline health care workers. Emerg Infect Dis (2011) 0.97
Rate of decline of antibody titers to pandemic influenza A (H1N1-2009) by hemagglutination inhibition and virus microneutralization assays in a cohort of seroconverting adults in Singapore. BMC Infect Dis (2014) 0.95
Factors influencing infection by pandemic influenza A(H1N1)pdm09 over three epidemic waves in Singapore. Influenza Other Respir Viruses (2013) 0.93
Inferring influenza infection attack rate from seroprevalence data. PLoS Pathog (2014) 0.91
Cumulative incidence of pandemic influenza A (H1N1) 2009 by a community-based serological cohort study in Selenghe Province, Mongolia. Influenza Other Respir Viruses (2012) 0.91
International Laboratory Comparison of Influenza Microneutralization Assays for A(H1N1)pdm09, A(H3N2), and A(H5N1) Influenza Viruses by CONSISE. Clin Vaccine Immunol (2015) 0.87
Sero-prevalence and incidence of A/H1N1 2009 influenza infection in Scotland in winter 2009-2010. PLoS One (2011) 0.86
Seroepidemiologic effects of influenza A(H1N1)pdm09 in Australia, New Zealand, and Singapore. Emerg Infect Dis (2013) 0.85
Antibody response of healthy children to pandemic A/H1N1/2009 influenza virus. Virol J (2011) 0.81
Seroprevalence of pandemic (H1N1) 2009 in pregnant women in China: an observational study. PLoS One (2011) 0.79
Does homologous reinfection drive multiple-wave influenza outbreaks? Accounting for immunodynamics in epidemiological models. Epidemics (2013) 0.79
Teacher led school-based surveillance can allow accurate tracking of emerging infectious diseases - evidence from serial cross-sectional surveys of febrile respiratory illness during the H1N1 2009 influenza pandemic in Singapore. BMC Infect Dis (2012) 0.78
The first cases of 2009 pandemic influenza A (H1N1) virus infection in the United States: a serologic investigation demonstrating early transmission. Influenza Other Respir Viruses (2012) 0.77
Little evidence of subclinical avian influenza virus infections among rural villagers in Cambodia. PLoS One (2014) 0.77
A novel benzo-heterocyclic amine derivative N30 inhibits influenza virus replication by depression of Inosine-5'-Monophospate Dehydrogenase activity. Virol J (2017) 0.75
Statistical identifiability and sample size calculations for serial seroepidemiology. Epidemics (2015) 0.75
Serological response of patients with influenza A (H1N1) pdm09-associated pneumonia: an observational study. PLoS One (2013) 0.75
Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med (2009) 42.75
Pandemic potential of a strain of influenza A (H1N1): early findings. Science (2009) 26.24
Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus. N Engl J Med (2009) 15.02
Incidence of 2009 pandemic influenza A H1N1 infection in England: a cross-sectional serological study. Lancet (2010) 12.43
Comparative epidemiology of pandemic and seasonal influenza A in households. N Engl J Med (2010) 5.90
Response to a monovalent 2009 influenza A (H1N1) vaccine. N Engl J Med (2009) 5.46
Prior H1N1 influenza infection and susceptibility of Cleveland Family Study participants during the H2N2 pandemic of 1957: an experiment of nature. J Infect Dis (2005) 5.19
Immunogenicity of a monovalent 2009 influenza A(H1N1) vaccine in infants and children: a randomized trial. JAMA (2009) 3.32
2009 influenza A(H1N1) seroconversion rates and risk factors among distinct adult cohorts in Singapore. JAMA (2010) 3.05
Real-time epidemic monitoring and forecasting of H1N1-2009 using influenza-like illness from general practice and family doctor clinics in Singapore. PLoS One (2010) 2.94
Diagnosis of influenza in the community: relationship of clinical diagnosis to confirmed virological, serologic, or molecular detection of influenza. Arch Intern Med (2001) 2.34
Recommended viruses for influenza vaccines for use in the 2010-2011 northern hemisphere influenza season. Wkly Epidemiol Rec (2010) 2.10
Seroprotection rate, mean fold increase, seroconversion rate: which parameter adequately expresses seroresponse to influenza vaccination? Virus Res (2004) 1.90
Seroprevalence Following the Second Wave of Pandemic 2009 H1N1 Influenza. PLoS Curr (2010) 1.57
Seroepidemiological studies of pandemic influenza A (H1N1) 2009 virus. Wkly Epidemiol Rec (2010) 1.54
Effectiveness of public health measures in mitigating pandemic influenza spread: a prospective sero-epidemiological cohort study. J Infect Dis (2010) 1.26
Pandemic (H1N1) 2009 surveillance and prevalence of seasonal influenza, Singapore. Emerg Infect Dis (2010) 1.16
Symptomatic infections less frequent with H1N1pdm than with seasonal strains: Antoine Flahault, Xavier de Lamballerie, Camille Pelat, Nicolas Salez, Thomas Hanslik. PLoS Curr (2009) 1.08
An outbreak of "hong Kong 'flu" in Singapore. II. Virological and serological report. Singapore Med J (1970) 1.01
Influenza A (H1N1-2009) pandemic in Singapore--public health control measures implemented and lessons learnt. Ann Acad Med Singapore (2010) 0.94
The global circulation of seasonal influenza A (H3N2) viruses. Science (2008) 10.05
Risk factors for severe outcomes following 2009 influenza A (H1N1) infection: a global pooled analysis. PLoS Med (2011) 4.02
Naturally acquired human Plasmodium knowlesi infection, Singapore. Emerg Infect Dis (2008) 3.63
The largest outbreak of hand; foot and mouth disease in Singapore in 2008: the role of enterovirus 71 and coxsackievirus A strains. Int J Infect Dis (2010) 3.49
Emergence and spread of oseltamivir-resistant A(H1N1) influenza viruses in Oceania, South East Asia and South Africa. Antiviral Res (2009) 3.39
Substitutions near the receptor binding site determine major antigenic change during influenza virus evolution. Science (2013) 3.38
Severe acute respiratory syndrome (SARS) in Singapore: clinical features of index patient and initial contacts. Emerg Infect Dis (2003) 3.10
2009 influenza A(H1N1) seroconversion rates and risk factors among distinct adult cohorts in Singapore. JAMA (2010) 3.05
Real-time epidemic monitoring and forecasting of H1N1-2009 using influenza-like illness from general practice and family doctor clinics in Singapore. PLoS One (2010) 2.94
Performance of influenza rapid point-of-care tests in the detection of swine lineage A(H1N1) influenza viruses. Influenza Other Respir Viruses (2009) 2.75
Persistent arthralgia induced by Chikungunya virus infection is associated with interleukin-6 and granulocyte macrophage colony-stimulating factor. J Infect Dis (2011) 2.69
Performance of six influenza rapid tests in detecting human influenza in clinical specimens. J Clin Virol (2007) 2.62
Zanamivir-resistant influenza viruses with a novel neuraminidase mutation. J Virol (2009) 2.59
Influenza vaccine strain selection and recent studies on the global migration of seasonal influenza viruses. Vaccine (2008) 2.56
First case of E anophelis outbreak in an intensive-care unit. Lancet (2013) 2.26
Early Dengue infection and outcome study (EDEN) - study design and preliminary findings. Ann Acad Med Singapore (2006) 2.12
Hajj-associated outbreak strain of Neisseria meningitidis serogroup W135: estimates of the attack rate in a defined population and the risk of invasive disease developing in carriers. Clin Infect Dis (2003) 2.12
Entomologic and virologic investigation of Chikungunya, Singapore. Emerg Infect Dis (2009) 2.10
Distributions of exons and introns in the human genome. In Silico Biol (2004) 2.06
MicroRNA-10b is overexpressed in pancreatic cancer, promotes its invasiveness, and correlates with a poor prognosis. Surgery (2011) 2.06
IL-1beta, IL-6, and RANTES as biomarkers of Chikungunya severity. PLoS One (2009) 2.04
Susceptibility of human influenza viruses from Australasia and South East Asia to the neuraminidase inhibitors zanamivir and oseltamivir. Antiviral Res (2004) 1.98
Re-emergence of Chikungunya virus in South-east Asia: virological evidence from Sri Lanka and Singapore. J Gen Virol (2009) 1.85
Dengue virus surveillance for early warning, Singapore. Emerg Infect Dis (2010) 1.81
Oseltamivir ring prophylaxis for containment of 2009 H1N1 influenza outbreaks. N Engl J Med (2010) 1.79
The out of Africa model of varicella-zoster virus evolution: single nucleotide polymorphisms and private alleles distinguish Asian clades from European/North American clades. Vaccine (2003) 1.72
Optical coherence tomography patterns as predictors of visual outcome in dengue-related maculopathy. Retina (2010) 1.70
Efficacy of soap and water and alcohol-based hand-rub preparations against live H1N1 influenza virus on the hands of human volunteers. Clin Infect Dis (2009) 1.67
Rapid detection and simultaneous subtype differentiation of influenza A viruses by real time PCR. J Virol Methods (2004) 1.66
Host-pathogen time series data in wildlife support a transmission function between density and frequency dependence. Proc Natl Acad Sci U S A (2009) 1.65
In vitro generation of neuraminidase inhibitor resistance in A(H5N1) influenza viruses. Antimicrob Agents Chemother (2009) 1.64
Economic impact of dengue illness and the cost-effectiveness of future vaccination programs in Singapore. PLoS Negl Trop Dis (2011) 1.63
A novel genomics approach for the identification of drug targets in pathogens, with special reference to Pseudomonas aeruginosa. In Silico Biol (2004) 1.62
Multiple infections with seasonal influenza A virus induce cross-protective immunity against A(H1N1) pandemic influenza virus in a ferret model. J Infect Dis (2010) 1.61
Active infection of human blood monocytes by Chikungunya virus triggers an innate immune response. J Immunol (2010) 1.60
MDCK-SIAT1 cells show improved isolation rates for recent human influenza viruses compared to conventional MDCK cells. J Clin Microbiol (2008) 1.59
Accuracy and user-acceptability of HIV self-testing using an oral fluid-based HIV rapid test. PLoS One (2012) 1.58
Direct detection of enterovirus 71 (EV71) in clinical specimens from a hand, foot, and mouth disease outbreak in Singapore by reverse transcription-PCR with universal enterovirus and EV71-specific primers. J Clin Microbiol (2002) 1.58
Retinal hemorrhages in 4 patients with dengue fever. Emerg Infect Dis (2005) 1.54
Lack of efficacy of prophylactic platelet transfusion for severe thrombocytopenia in adults with acute uncomplicated dengue infection. Clin Infect Dis (2009) 1.53
Evaluation of the NS1 rapid test and the WHO dengue classification schemes for use as bedside diagnosis of acute dengue fever in adults. Am J Trop Med Hyg (2011) 1.52
Influenza excess mortality from 1950-2000 in tropical Singapore. PLoS One (2009) 1.50
Confirmed adult dengue deaths in Singapore: 5-year multi-center retrospective study. BMC Infect Dis (2011) 1.49
Improving the clinical diagnosis of influenza--a comparative analysis of new influenza A (H1N1) cases. PLoS One (2009) 1.47
Epidemiology of travel-associated pandemic (H1N1) 2009 infection in 116 patients, Singapore. Emerg Infect Dis (2010) 1.47
Three-Month Real-Time Dengue Forecast Models: An Early Warning System for Outbreak Alerts and Policy Decision Support in Singapore. Environ Health Perspect (2015) 1.46
Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity. Proc Natl Acad Sci U S A (2009) 1.44
MCP-1 antibody treatment enhances damage and impedes repair of the alveolar epithelium in influenza pneumonitis. Am J Respir Cell Mol Biol (2009) 1.43
Oseltamivir resistance and the H274Y neuraminidase mutation in seasonal, pandemic and highly pathogenic influenza viruses. Drugs (2009) 1.41
Internet search limitations and pandemic influenza, Singapore. Emerg Infect Dis (2010) 1.38
Use of Prediction Models for Risk Analysis and Decision-Making in Public Health-The Catch-22 Conundrum. Ann Acad Med Singapore (2016) 1.38
Clinico-genetic characterisation of an encephalitic Dengue virus 4 associated with multi-organ involvement. J Clin Virol (2013) 1.38
Laboratory-acquired severe acute respiratory syndrome. N Engl J Med (2004) 1.37
Early appearance of neutralizing immunoglobulin G3 antibodies is associated with chikungunya virus clearance and long-term clinical protection. J Infect Dis (2012) 1.36
Comparison of the incidence of influenza in relation to climate factors during 2000-2007 in five countries. J Med Virol (2010) 1.36
Simple clinical and laboratory predictors of Chikungunya versus dengue infections in adults. PLoS Negl Trop Dis (2012) 1.34
Molecular characterization of newly emerged blaKPC-2-producing Klebsiella pneumoniae in Singapore. J Clin Microbiol (2011) 1.33
Evaluation of Chikungunya diagnostic assays: differences in sensitivity of serology assays in two independent outbreaks. PLoS Negl Trop Dis (2010) 1.32
Assessing the viral fitness of oseltamivir-resistant influenza viruses in ferrets, using a competitive-mixtures model. J Virol (2010) 1.31
Cross-reactive antibodies to pandemic (H1N1) 2009 virus, Singapore. Emerg Infect Dis (2010) 1.30
Diabetes with hypertension as risk factors for adult dengue hemorrhagic fever in a predominantly dengue serotype 2 epidemic: a case control study. PLoS Negl Trop Dis (2012) 1.29
Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein. EMBO Mol Med (2012) 1.29
Chikungunya: a bending reality. Microbes Infect (2009) 1.27
Effectiveness of public health measures in mitigating pandemic influenza spread: a prospective sero-epidemiological cohort study. J Infect Dis (2010) 1.26
Utilities and limitations of the World Health Organization 2009 warning signs for adult dengue severity. PLoS Negl Trop Dis (2013) 1.25
Inactivated trivalent seasonal influenza vaccine induces limited cross-reactive neutralizing antibody responses against 2009 pandemic and 1934 PR8 H1N1 strains. Vaccine (2010) 1.23
Injectable peramivir mitigates disease and promotes survival in ferrets and mice infected with the highly virulent influenza virus, A/Vietnam/1203/04 (H5N1). Virology (2008) 1.23
Influenza in the tropics. Lancet Infect Dis (2009) 1.23
Identification of a human influenza type B strain with reduced sensitivity to neuraminidase inhibitor drugs. Virus Res (2004) 1.22
High proportion of influenza B characterises the 2008 influenza season in Victoria. Commun Dis Intell Q Rep (2009) 1.22
Longitudinal analysis of the human antibody response to Chikungunya virus infection: implications for serodiagnosis and vaccine development. J Virol (2012) 1.21
Antigenic drift of the pandemic 2009 A(H1N1) influenza virus in A ferret model. PLoS Pathog (2013) 1.20
Strategies for antiviral stockpiling for future influenza pandemics: a global epidemic-economic perspective. J R Soc Interface (2011) 1.20