Survival benefit with proapoptotic molecular and pathologic responses from dual targeting of mammalian target of rapamycin and epidermal growth factor receptor in a preclinical model of pancreatic neuroendocrine carcinogenesis.

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Published in J Clin Oncol on September 07, 2010

Authors

Christopher W Chiu1, Hiroaki Nozawa, Douglas Hanahan

Author Affiliations

1: University of California, San Francisco, CA, USA.

Associated clinical trials:

Efficacy and Safety of Everolimus (RAD001) Compared to Placebo in Patients With Advanced Neuroendocrine Tumors (RADIANT-3) | NCT00510068

RAD001 and Erlotinib in Patients With Neuroendocrine Tumors | NCT00843531

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