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About
Peter Hirth
Author PubWeight™ 40.38
‹?›
Top papers
Rank
Title
Journal
Year
PubWeight™
‹?›
1
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity.
Proc Natl Acad Sci U S A
2008
17.41
2
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma.
Nature
2010
16.12
3
Vemurafenib: the first drug approved for BRAF-mutant cancer.
Nat Rev Drug Discov
2012
3.09
4
Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor.
N Engl J Med
2015
1.75
5
Pharmacodynamic characterization of the efficacy signals due to selective BRAF inhibition with PLX4032 in malignant melanoma.
Neoplasia
2010
1.48
6
Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor.
Proc Natl Acad Sci U S A
2013
0.91
7
The Raf kinase inhibitor PLX5568 slows cyst proliferation in rat polycystic kidney disease but promotes renal and hepatic fibrosis.
Nephrol Dial Transplant
2011
0.83
8
A bradykinin antagonist and a caspase inhibitor prevent severe pulmonary hypertension in a rat model.
Can J Physiol Pharmacol
2002
0.82