Liangyou Rui

Author PubWeight™ 41.40‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Neuronal SH2B1 is essential for controlling energy and glucose homeostasis. J Clin Invest 2007 2.42
2 Recent advances in understanding leptin signaling and leptin resistance. Am J Physiol Endocrinol Metab 2009 2.27
3 Identification of SH2-B as a key regulator of leptin sensitivity, energy balance, and body weight in mice. Cell Metab 2005 2.04
4 SH2B1 enhances leptin signaling by both Janus kinase 2 Tyr813 phosphorylation-dependent and -independent mechanisms. Mol Endocrinol 2007 1.96
5 Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance. Mol Cell Biol 2004 1.65
6 Identification of MUP1 as a regulator for glucose and lipid metabolism in mice. J Biol Chem 2009 1.56
7 SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin. J Biol Chem 2004 1.51
8 SH2B regulation of growth, metabolism, and longevity in both insects and mammals. Cell Metab 2010 1.34
9 Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice. Hepatology 2009 1.31
10 SH2B1 enhances insulin sensitivity by both stimulating the insulin receptor and inhibiting tyrosine dephosphorylation of insulin receptor substrate proteins. Diabetes 2009 1.28
11 PKA phosphorylation couples hepatic inositol-requiring enzyme 1alpha to glucagon signaling in glucose metabolism. Proc Natl Acad Sci U S A 2011 1.17
12 Overexpression or ablation of JNK in skeletal muscle has no effect on glycogen synthase activity. Am J Physiol Cell Physiol 2004 1.16
13 Differential role of SH2-B and APS in regulating energy and glucose homeostasis. Endocrinology 2006 1.13
14 NF-κB–inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action. Nat Med 2012 1.10
15 Transcriptional repressor E4-binding protein 4 (E4BP4) regulates metabolic hormone fibroblast growth factor 21 (FGF21) during circadian cycles and feeding. J Biol Chem 2010 1.08
16 Leptin signaling and leptin resistance. Front Med 2013 1.08
17 Identification of SH2B2beta as an inhibitor for SH2B1- and SH2B2alpha-promoted Janus kinase-2 activation and insulin signaling. Endocrinology 2007 1.03
18 Leptin stimulates both JAK2-dependent and JAK2-independent signaling pathways. J Biol Chem 2008 1.02
19 Human SH2B1 mutations are associated with maladaptive behaviors and obesity. J Clin Invest 2012 1.01
20 Lipocalin-13 regulates glucose metabolism by both insulin-dependent and insulin-independent mechanisms. Mol Cell Biol 2010 0.98
21 Major urinary protein regulation of chemical communication and nutrient metabolism. Vitam Horm 2010 0.95
22 Mouse hepatocyte overexpression of NF-κB-inducing kinase (NIK) triggers fatal macrophage-dependent liver injury and fibrosis. Hepatology 2014 0.93
23 Critical role of the Src homology 2 (SH2) domain of neuronal SH2B1 in the regulation of body weight and glucose homeostasis in mice. Endocrinology 2010 0.91
24 Shp2 controls female body weight and energy balance by integrating leptin and estrogen signals. Mol Cell Biol 2012 0.90
25 Hepatic TRAF2 regulates glucose metabolism through enhancing glucagon responses. Diabetes 2012 0.88
26 Lipocalin 13 protein protects against hepatic steatosis by both inhibiting lipogenesis and stimulating fatty acid β-oxidation. J Biol Chem 2011 0.87
27 Neuronal Cbl controls biosynthesis of insulin-like peptides in Drosophila melanogaster. Mol Cell Biol 2012 0.85
28 Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation. J Cell Biol 2013 0.85
29 SH2B1 in β-cells regulates glucose metabolism by promoting β-cell survival and islet expansion. Diabetes 2013 0.84
30 Glucose enhances leptin signaling through modulation of AMPK activity. PLoS One 2012 0.84
31 Intracellular lipid content is a key intrinsic determinant for hepatocyte viability and metabolic and inflammatory states in mice. Am J Physiol Endocrinol Metab 2013 0.83
32 Herbal constituent sequoyitol improves hyperglycemia and glucose intolerance by targeting hepatocytes, adipocytes, and β-cells. Am J Physiol Endocrinol Metab 2012 0.82
33 Adapter protein SH2-Bbeta stimulates actin-based motility of Listeria monocytogenes in a vasodilator-stimulated phosphoprotein (VASP)-dependent fashion. Infect Immun 2007 0.81
34 Lipocalin 13 regulation of glucose and lipid metabolism in obesity. Vitam Horm 2013 0.78
35 Functional characterization of obesity-associated variants involving the α and β isoforms of human SH2B1. Endocrinology 2014 0.77
36 SH2B1 in β-cells promotes insulin expression and glucose metabolism in mice. Mol Endocrinol 2014 0.76