Comparison of the new high sensitive cardiac troponin T with myoglobin, h-FABP and cTnT for early identification of myocardial necrosis in the acute coronary syndrome.

PubWeight™: 1.08‹?› | Rank: Top 10%

🔗 View Article (PMID 20852870)

Published in Clin Res Cardiol on September 18, 2010

Authors

Kerstin Kurz1, Evangelos Giannitsis, Maike Becker, Georg Hess, Dietmar Zdunek, Hugo A Katus

Author Affiliations

1: Medizinische Klinik, Abteilung für Innere Medizin III, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 410, Heidelberg, Germany. Kerstin.Kurz@med.uni-heidelberg.de

Articles citing this

Diagnostic accuracy of single baseline measurement of Elecsys Troponin T high-sensitive assay for diagnosis of acute myocardial infarction in emergency department: systematic review and meta-analysis. BMJ (2015) 1.87

Smoking restrictions and hospitalization for acute coronary events in Germany. Clin Res Cardiol (2012) 1.08

Comparison of the temporal release pattern of copeptin with conventional biomarkers in acute myocardial infarction. Clin Res Cardiol (2011) 1.00

Pre- and early in-hospital procedures in patients with acute coronary syndromes: first results of the "German chest pain unit registry". Clin Res Cardiol (2012) 0.95

Proteomic mapping of proteins released during necrosis and apoptosis from cultured neonatal cardiac myocytes. Am J Physiol Cell Physiol (2014) 0.92

Combined determination of highly sensitive troponin T and copeptin for early exclusion of acute myocardial infarction: first experience in an emergency department of a general hospital. Vasc Health Risk Manag (2011) 0.89

Cardiogoniometry as a diagnostic tool in patients with acute coronary syndromes: results of the CGM@ACS trial. Clin Res Cardiol (2012) 0.86

Impact of copeptin on diagnosis, risk stratification, and intermediate-term prognosis of acute coronary syndromes. Clin Res Cardiol (2013) 0.86

Cost-effectiveness of cardiac biomarkers as screening test in acute chest pain. J Cardiovasc Thorac Res (2014) 0.81

Association of high-sensitivity assayed troponin I with cardiovascular phenotypes in the general population: the population-based Gutenberg health study. Clin Res Cardiol (2013) 0.81

A simple score for rapid risk assessment of non-high-risk pulmonary embolism. Clin Res Cardiol (2012) 0.81

Atrial fibrillation, elevated troponin, ischemic stroke and adverse outcomes: understanding the connection. Clin Res Cardiol (2013) 0.81

Cardiac troponin T concentrations above the 99th percentile value as measured by a new high-sensitivity assay predict long-term prognosis in patients with acute coronary syndromes undergoing routine early invasive strategy. Clin Res Cardiol (2011) 0.80

No Added Value of Novel Biomarkers in the Diagnostic Assessment of Patients Suspected of Acute Coronary Syndrome. PLoS One (2015) 0.80

Criteria of the German Society of Cardiology for the establishment of chest pain units: update 2014. Clin Res Cardiol (2015) 0.79

Biological variation of high sensitive Troponin T in stable heart failure patients with ischemic or dilated cardiomyopathy. Clin Res Cardiol (2011) 0.79

Utility of Heart-type Fatty Acid Binding Protein as a New Biochemical Marker for the Early Diagnosis of Acute Coronary Syndrome. J Clin Diagn Res (2015) 0.79

Diagnostic accuracy of sensitive or high-sensitive troponin on presentation for myocardial infarction: a meta-analysis and systematic review. Vasc Health Risk Manag (2014) 0.79

TNF-α, myocardial perfusion and function in patients with ST-segment elevation myocardial infarction and primary percutaneous coronary intervention. Clin Res Cardiol (2012) 0.78

Diagnosis of Non-ST-Elevation Acute Coronary Syndrome by the Measurement of Heart-Type Fatty Acid Binding Protein in Serum: A Prospective Case Control Study. J Biomark (2014) 0.75

Articles cited by this

Universal definition of myocardial infarction. J Am Coll Cardiol (2007) 8.68

Early diagnosis of myocardial infarction with sensitive cardiac troponin assays. N Engl J Med (2009) 8.05

Sensitive troponin I assay in early diagnosis of acute myocardial infarction. N Engl J Med (2009) 6.62

Analytical validation of a high-sensitivity cardiac troponin T assay. Clin Chem (2009) 3.24

Ninety-minute exclusion of acute myocardial infarction by use of quantitative point-of-care testing of myoglobin and troponin I. Circulation (2001) 2.22

High-sensitivity cardiac troponin T for early prediction of evolving non-ST-segment elevation myocardial infarction in patients with suspected acute coronary syndrome and negative troponin results on admission. Clin Chem (2010) 2.14

Short- and long-term biological variation in cardiac troponin I measured with a high-sensitivity assay: implications for clinical practice. Clin Chem (2008) 2.11

National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: clinical characteristics and utilization of biochemical markers in acute coronary syndromes. Clin Chem (2007) 1.82

Incremental value of copeptin for rapid rule out of acute myocardial infarction. J Am Coll Cardiol (2009) 1.71

Validation of the 99th percentile cutoff independent of assay imprecision (CV) for cardiac troponin monitoring for ruling out myocardial infarction. Clin Chem (2005) 1.58

Release of heart fatty acid-binding protein into plasma after acute myocardial infarction in man. Mol Cell Biochem (1992) 1.34

Diagnostic value of serial measurement of cardiac markers in patients with chest pain: limited value of adding myoglobin to troponin I for exclusion of myocardial infarction. Am Heart J (2004) 1.26

Use of the Centaur TnI-Ultra assay for detection of myocardial infarction and adverse events in patients presenting with symptoms suggestive of acute coronary syndrome. Clin Chem (2008) 1.23

Early detection of acute myocardial infarction: additional diagnostic information from serum concentrations of myoglobin in patients without ST elevation. Br Heart J (1990) 1.19

Ninety-minute accelerated critical pathway for chest pain evaluation. Am J Cardiol (2001) 1.10

Office cardiologists cooperative study on whole blood rapid panel tests in patients with suspicious acute myocardial infarction: comparison between heart-type fatty acid-binding protein and troponin T tests. Circ J (2004) 0.97

Clinical assessment of heart-type fatty acid binding protein in early diagnosis of acute coronary syndrome. Eur J Emerg Med (2008) 0.96

Evaluation of a new rapid quantitative immunoassay for serum myoglobin versus CK-MB for ruling out acute myocardial infarction in the emergency department. Ann Emerg Med (1994) 0.83

Role of heart-type fatty acid-binding protein in early detection of acute myocardial infarction. Clin Chem (2000) 0.82

Early markers of myocardial injury: cTnI is enough. Clin Chim Acta (2008) 0.80

Development of a rapid microparticle-enhanced turbidimetric immunoassay for plasma fatty acid-binding protein, an early marker of acute myocardial infarction. Clin Chem (1998) 0.78

Minor troponin T elevation in patients 6 months after acute myocardial infarction: an observational study. Clin Res Cardiol (2009) 0.75

High-sensitive cardiac troponin assays: application for prime-time use. Biomark Med (2010) 0.75

The clinical dilemma of positive results of high-sensitive troponin assays. Am J Cardiol (2009) 0.75

A prospective study of an algorithm using cardiac troponin I and myoglobin as adjuncts in the diagnosis of acute myocardial infarction and intermediate coronary syndromes in a veteran's hospital. Clin Cardiol (2000) 0.75

Articles by these authors

Universal definition of myocardial infarction. Circulation (2007) 11.69

Third universal definition of myocardial infarction. J Am Coll Cardiol (2012) 8.59

Third universal definition of myocardial infarction. Circulation (2012) 8.47

Third universal definition of myocardial infarction. Eur Heart J (2012) 7.98

Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy. N Engl J Med (2015) 6.00

Tumor regression in cancer patients by very low doses of a T cell-engaging antibody. Science (2008) 5.30

Myocardial infarction accelerates atherosclerosis. Nature (2012) 4.48

Hypertrophy of the heart: a new therapeutic target? Circulation (2004) 4.45

Persistent GB virus C infection and survival in HIV-infected men. N Engl J Med (2004) 4.06

MicroRNA-34a regulates cardiac ageing and function. Nature (2013) 4.03

High-mobility group box-1 in ischemia-reperfusion injury of the heart. Circulation (2008) 3.46

Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the carvedilol prospective randomized cumulative survival (COPERNICUS) study. Circulation (2002) 3.34

Analytical validation of a high-sensitivity cardiac troponin T assay. Clin Chem (2009) 3.24

Exercise and respiratory training improve exercise capacity and quality of life in patients with severe chronic pulmonary hypertension. Circulation (2006) 2.67

The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload. Proc Natl Acad Sci U S A (2009) 2.66

Serial changes in highly sensitive troponin I assay and early diagnosis of myocardial infarction. JAMA (2011) 2.61

Cardiac troponin I but not cardiac troponin T induces severe autoimmune inflammation in the myocardium. Circulation (2006) 2.58

Tubular markers do not predict the decline in glomerular filtration rate in type 1 diabetic patients with overt nephropathy. Kidney Int (2011) 2.52

Targeted next-generation sequencing for the molecular genetic diagnostics of cardiomyopathies. Circ Cardiovasc Genet (2011) 2.45

Circadian profile of cardiac autonomic nervous modulation in healthy subjects: differing effects of aging and gender on heart rate variability. J Cardiovasc Electrophysiol (2003) 2.41

Cardiac myosin light chain-2: a novel essential component of thick-myofilament assembly and contractility of the heart. Circ Res (2006) 2.36

Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart. Genes Dev (2006) 2.29

Influence of pretreatment systolic blood pressure on the effect of carvedilol in patients with severe chronic heart failure: the Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) study. J Am Coll Cardiol (2004) 2.29

Prehospital initiation of tirofiban in patients with ST-elevation myocardial infarction undergoing primary angioplasty (On-TIME 2): a multicentre, double-blind, randomised controlled trial. Lancet (2008) 2.26

Rescue renal sympathetic denervation in a patient with ventricular electrical storm refractory to endo- and epicardial catheter ablation. Clin Res Cardiol (2014) 2.15

Absolute and relative kinetic changes of high-sensitivity cardiac troponin T in acute coronary syndrome and in patients with increased troponin in the absence of acute coronary syndrome. Clin Chem (2011) 2.14

Toward the blood-borne miRNome of human diseases. Nat Methods (2011) 2.14

High-sensitivity cardiac troponin T for early prediction of evolving non-ST-segment elevation myocardial infarction in patients with suspected acute coronary syndrome and negative troponin results on admission. Clin Chem (2010) 2.14

Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stress. Nat Med (2004) 2.11

Skeletal scintigraphy indicates disease severity of cardiac involvement in patients with senile systemic amyloidosis. Int J Cardiol (2011) 2.10

Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy. Nat Med (2009) 2.08

Improved cardiac gene transfer by transcriptional and transductional targeting of adeno-associated viral vectors. Cardiovasc Res (2006) 2.07

Interpreting changes in troponin--clinical judgment is essential. Clin Chem (2012) 2.06

Stent thrombosis with ticagrelor versus clopidogrel in patients with acute coronary syndromes: an analysis from the prospective, randomized PLATO trial. Circulation (2013) 2.03

Inhibition of IL-17A attenuates atherosclerotic lesion development in apoE-deficient mice. J Immunol (2009) 2.03

Comparison of a 3-hour versus a 6-hour sampling-protocol using high-sensitivity cardiac troponin T for rule-out and rule-in of non-STEMI in an unselected emergency department population. Int J Cardiol (2012) 2.02

How to use high-sensitivity cardiac troponins in acute cardiac care. Eur Heart J (2012) 2.00

The sarcomeric Z-disc: a nodal point in signalling and disease. J Mol Med (Berl) (2006) 1.99

High anti-lymphoma activity of bendamustine/mitoxantrone/rituximab in rituximab pretreated relapsed or refractory indolent lymphomas and mantle cell lymphomas. A multicenter phase II study of the German Low Grade Lymphoma Study Group (GLSG). Leuk Lymphoma (2007) 1.89

Recommendations for the use of cardiac troponin measurement in acute cardiac care. Eur Heart J (2010) 1.88

MicroRNA signatures in total peripheral blood as novel biomarkers for acute myocardial infarction. Basic Res Cardiol (2010) 1.87

Determinants of troponin release in patients with stable coronary artery disease: insights from CT angiography characteristics of atherosclerotic plaque. Heart (2010) 1.87

Wnt signaling is critical for maladaptive cardiac hypertrophy and accelerates myocardial remodeling. Hypertension (2010) 1.84

Longitudinal left ventricular function for prediction of survival in systemic light-chain amyloidosis: incremental value compared with clinical and biochemical markers. J Am Coll Cardiol (2012) 1.84

Renal sympathetic denervation therapy in the real world: results from the Heidelberg registry. Clin Res Cardiol (2013) 1.78

Prognostic value of high-dose dobutamine stress magnetic resonance imaging in 1,493 consecutive patients: assessment of myocardial wall motion and perfusion. J Am Coll Cardiol (2010) 1.78

Biomarkers in relation to the effects of ticagrelor in comparison with clopidogrel in non-ST-elevation acute coronary syndrome patients managed with or without in-hospital revascularization: a substudy from the Prospective Randomized Platelet Inhibition and Patient Outcomes (PLATO) trial. Circulation (2013) 1.77

Connexin 43 gene therapy prevents persistent atrial fibrillation in a porcine model. Cardiovasc Res (2011) 1.76

Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue. Circulation (2007) 1.73

Cardiac troponin level elevations not related to acute coronary syndromes. Nat Rev Cardiol (2013) 1.71

High-sensitive troponin T: a novel biomarker for prognosis and disease severity in patients with pulmonary arterial hypertension. Clin Sci (Lond) (2010) 1.70

Patient alert in implantable cardioverter defibrillators: toy or tool? J Am Coll Cardiol (2004) 1.68

S100A1 genetically targeted therapy reverses dysfunction of human failing cardiomyocytes. J Am Coll Cardiol (2011) 1.68

Prevention of cardiomyopathy in delta-sarcoglycan knockout mice after systemic transfer of targeted adeno-associated viral vectors. Cardiovasc Res (2009) 1.67

Safety and clinical activity of a combination therapy comprising two antibody-based targeting agents for the treatment of non-Hodgkin lymphoma: results of a phase I/II study evaluating the immunoconjugate inotuzumab ozogamicin with rituximab. J Clin Oncol (2013) 1.65

Multivariate miRNA signatures as biomarkers for non-ischaemic systolic heart failure. Eur Heart J (2013) 1.65

Effects of initiating carvedilol in patients with severe chronic heart failure: results from the COPERNICUS Study. JAMA (2003) 1.64

GB virus C (GBV-C) infection in hepatitis C virus (HCV)/HIV-coinfected patients receiving HCV treatment: importance of the GBV-C genotype. J Infect Dis (2006) 1.64

Prevalence of different gadolinium enhancement patterns in patients after heart transplantation. J Am Coll Cardiol (2008) 1.63

There is no transmural heterogeneity in an index of action potential duration in the canine left ventricle. Heart Rhythm (2009) 1.59

Prognostic impact of plasma N-terminal pro-brain natriuretic peptide in severe chronic congestive heart failure: a substudy of the Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) trial. Circulation (2004) 1.59

Genetic suppression of atrial fibrillation using a dominant-negative ether-a-go-go-related gene mutant. Heart Rhythm (2011) 1.59

Cardiac adenoviral S100A1 gene delivery rescues failing myocardium. J Clin Invest (2004) 1.58

Regulation of cardiac cAMP synthesis and contractility by nucleoside diphosphate kinase B/G protein beta gamma dimer complexes. Circ Res (2007) 1.58

MicroRNA-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting vascular endothelial growth factor signaling. Circ Res (2012) 1.56

Efficacy and safety of imatinib in adult patients with c-kit-positive acute myeloid leukemia. Blood (2004) 1.55

Mechanisms of disease: hypertrophic cardiomyopathy. Nat Rev Cardiol (2011) 1.55

Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model. Sci Transl Med (2011) 1.54

Cardiospecificity of the 3rd generation cardiac troponin T assay during and after a 216 km ultra-endurance marathon run in Death Valley. Clin Res Cardiol (2007) 1.54

Strain-encoded cardiac magnetic resonance during high-dose dobutamine stress testing for the estimation of cardiac outcomes: comparison to clinical parameters and conventional wall motion readings. J Am Coll Cardiol (2011) 1.53

VEGF-PLCgamma1 pathway controls cardiac contractility in the embryonic heart. Genes Dev (2005) 1.53

Cardiac troponin elevations in patients without acute coronary syndrome. Circulation (2002) 1.53

Cardiac G-protein-coupled receptor kinase 2 ablation induces a novel Ca2+ handling phenotype resistant to adverse alterations and remodeling after myocardial infarction. Circulation (2012) 1.52

(90)Yttrium-ibritumomab-tiuxetan as first-line treatment for follicular lymphoma: 30 months of follow-up data from an international multicenter phase II clinical trial. J Clin Oncol (2012) 1.50

Purulent pericarditis and pleural empyema due to Staphylococcus aureus septicemia. Int J Cardiol (2006) 1.49

Injection of nerve growth factor into stellate ganglia improves norepinephrine reuptake into failing hearts. Hypertension (2005) 1.49

Beneficial effects of Mammalian target of rapamycin inhibition on left ventricular remodeling after myocardial infarction. J Am Coll Cardiol (2009) 1.46

Control of organ transplant-associated graft-versus-host disease by activated host lymphocyte infusions. Transplantation (2004) 1.45

Objective quantification of aortic valvular structures by cardiac computed tomography angiography in patients considered for transcatheter aortic valve implantation. Catheter Cardiovasc Interv (2013) 1.45

TLR4-mediated inflammatory activation of human coronary artery endothelial cells by LPS. Cardiovasc Res (2002) 1.45

Role of p22phox in angiotensin II and platelet-derived growth factor AA induced activator protein 1 activation in vascular smooth muscle cells. J Mol Med (Berl) (2003) 1.45

Impact of troponin I-autoantibodies in chronic dilated and ischemic cardiomyopathy. Basic Res Cardiol (2010) 1.44

Evidence of left ventricular contractile asynchrony by echocardiographic phase imaging in patients with type 2 diabetes mellitus and without clinically evident heart disease. Am J Cardiol (2006) 1.44

Tirofiban optimizes platelet inhibition for immediate percutaneous coronary intervention in high-risk acute coronary syndromes. Thromb Haemost (2008) 1.44