Published in IRB on September 21, 2010
Quantifying the risks of non-oncology phase I research in healthy volunteers: meta-analysis of phase I studies. BMJ (2015) 3.36
Improving understanding in the research informed consent process: a systematic review of 54 interventions tested in randomized control trials. BMC Med Ethics (2013) 2.38
Length and complexity of US and international HIV consent forms from federal HIV network trials. J Gen Intern Med (2011) 1.28
A randomized controlled trial of short and standard-length consent forms for a genetic cohort study: is longer better? J Epidemiol (2012) 0.97
Randomization to standard and concise informed consent forms: development of evidence-based consent practices. Contemp Clin Trials (2012) 0.95
A pilot study of simple interventions to improve informed consent in clinical research: feasibility, approach, and results. Clin Trials (2014) 0.89
Improving participant understanding of informed consent in an HIV-prevention clinical trial: a comparison of methods. AIDS Behav (2012) 0.88
Analysis of informed consent document utilization in a minimal-risk genetic study. Ann Intern Med (2011) 0.87
Research ethics. Aligning regulations and ethics in human research. Science (2012) 0.84
Use of mobile devices and the internet for multimedia informed consent delivery and data entry in a pediatric asthma trial: Study design and rationale. Contemp Clin Trials (2015) 0.80
The MICHR Genomic DNA BioLibrary: An Empirical Study of the Ethics of Biorepository Development. J Empir Res Hum Res Ethics (2015) 0.77
A review of approaches to improve participation of culturally and linguistically diverse populations in clinical trials. Trials (2016) 0.76
A Comparison of the Quality of Informed Consent for Clinical Trials of an Experimental Hookworm Vaccine Conducted in Developed and Developing Countries. PLoS Negl Trop Dis (2017) 0.75
Permission form synopses to improve parents' understanding of research: a randomized trial. J Perinatol (2017) 0.75
Improving biobank consent comprehension: a national randomized survey to assess the effect of a simplified form and review/retest intervention. Genet Med (2016) 0.75
Interventions to improve research participants' understanding in informed consent for research: a systematic review. JAMA (2004) 7.97
Readability standards for informed-consent forms as compared with actual readability. N Engl J Med (2003) 7.58
Quality of informed consent in cancer clinical trials: a cross-sectional survey. Lancet (2001) 6.07
Informed consent for clinical trials: a comparative study of standard versus simplified forms. J Natl Cancer Inst (1998) 3.89
Informed consent: study of quality of information given to participants in a clinical trial. BMJ (1991) 3.46
Payment of clinical research subjects. J Clin Invest (2005) 3.15
Obtaining informed consent. Form or substance. Arch Intern Med (1969) 2.52
Conventional consent with opting in versus simplified consent with opting out: an exploratory trial for studies that do not increase patient risk. J Pediatr (1998) 2.46
Randomized, controlled trial of an easy-to-read informed consent statement for clinical trial participation: a study of the Eastern Cooperative Oncology Group. J Clin Oncol (2003) 2.41
Are informed consent forms that describe clinical oncology research protocols readable by most patients and their families? J Clin Oncol (1994) 2.24
On paying money to research subjects: 'due' and 'undue' inducements. IRB (1981) 2.12
Money for research participation: does in jeopardize informed consent? Am J Bioeth (2001) 2.02
Can the written information to research subjects be improved?--an empirical study. J Med Ethics (1999) 1.88
Longer consent forms for clinical trials compromise patient understanding: so why are they lengthening? J Clin Oncol (2007) 1.66
Paying people to participate in research: why not? A response to Wilkinson and Moore. Bioethics (1997) 1.64
Modifying a standard industry clinical trial consent form improves patient information retention as part of the informed consent process. Acad Emerg Med (2001) 1.58
How informed is informed consent? The BHAT experience. Control Clin Trials (1981) 1.55
Justice for the professional guinea pig. Am J Bioeth (2001) 1.42
Informed consent documents: increasing comprehension by reducing reading level. IRB (1993) 1.42
Guinea pigs on the payroll: the ethics of paying research subjects. Account Res (1999) 1.39
Clinical research with economically disadvantaged populations. J Med Ethics (2007) 1.36
Improving understanding of research consent disclosures among persons with mental illness. Psychiatr Serv (2001) 1.36
Informed consent for research. Effects of readability, patient age, and education. J Am Geriatr Soc (1986) 1.35
Recall of informed consent information by healthy volunteers in clinical trials. QJM (2008) 1.24
Improving comprehension and recall of information for an HIV vaccine trial among women at risk for HIV: reading level simplification and inclusion of pictures to illustrate key concepts. AIDS Educ Prev (1999) 1.21
Conducting empirical research on informed consent: challenges and questions. IRB (2004) 1.14
Emergency medicine research consent form readability assessment. Ann Emerg Med (1997) 1.14
Case study. Is longer always better? Commentary. Hastings Cent Rep (2008) 0.79
The research subject as entrepreneur. Am J Bioeth (2001) 0.78
The limitations of "vulnerability" as a protection for human research participants. Am J Bioeth (2004) 14.06
What makes clinical research in developing countries ethical? The benchmarks of ethical research. J Infect Dis (2004) 9.65
Risks and benefits of phase 1 oncology trials, 1991 through 2002. N Engl J Med (2005) 8.25
Interventions to improve research participants' understanding in informed consent for research: a systematic review. JAMA (2004) 7.97
Are racial and ethnic minorities less willing to participate in health research? PLoS Med (2005) 7.88
Dealing with the long-term social implications of research. Am J Bioeth (2011) 5.41
How much is life worth: cetuximab, non-small cell lung cancer, and the $440 billion question. J Natl Cancer Inst (2009) 5.40
The debate over research on stored biological samples: what do sources think? Arch Intern Med (2002) 5.28
Misunderstanding in clinical research: distinguishing therapeutic misconception, therapeutic misestimation, and therapeutic optimism. IRB (2003) 3.82
Enduring and emerging challenges of informed consent. N Engl J Med (2015) 3.79
Clinical trials and medical care: defining the therapeutic misconception. PLoS Med (2007) 3.77
Descriptions of benefits and risks in consent forms for phase 1 oncology trials. N Engl J Med (2002) 3.62
Oversight of human participants research: identifying problems to evaluate reform proposals. Ann Intern Med (2004) 3.58
SHEA guideline for management of healthcare workers who are infected with hepatitis B virus, hepatitis C virus, and/or human immunodeficiency virus. Infect Control Hosp Epidemiol (2010) 3.44
Patients' decision-making process regarding participation in phase I oncology research. J Clin Oncol (2006) 2.72
Informed Consent. N Engl J Med (2017) 2.56
Moral distress: a growing problem in the health professions? Hastings Cent Rep (2010) 2.23
Adhesion formation after laparoscopic excision of endometriosis and lysis of adhesions. Fertil Steril (2005) 2.08
A systematic review of the empirical literature evaluating IRBs: what we know and what we still need to learn. J Empir Res Hum Res Ethics (2011) 2.03
Racial and ethnic differences in end-of-life costs: why do minorities cost more than whites? Arch Intern Med (2009) 2.02
More than the money: a review of the literature examining healthy volunteer motivations. Contemp Clin Trials (2010) 1.92
Paying research subjects: an analysis of current policies. Ann Intern Med (2002) 1.90
Place of death: U.S. trends since 1980. Health Aff (Millwood) (2004) 1.85
The ethics of paying for children's participation in research. J Pediatr (2002) 1.80
Participants in phase 1 oncology research trials: are they vulnerable? Arch Intern Med (2008) 1.74
Ethical climate, ethics stress, and the job satisfaction of nurses and social workers in the United States. Soc Sci Med (2007) 1.72
The invisible hand in clinical research: the study coordinator's critical role in human subjects protection. J Law Med Ethics (2002) 1.72
The quality of informed consent: mapping the landscape. A review of empirical data from developing and developed countries. J Med Ethics (2012) 1.69
Is emergency research without initial consent justified?: the consent substitute model. Arch Intern Med (2010) 1.65
Why patients continue to participate in clinical research. Arch Intern Med (2008) 1.62
Research on stored biological samples: the views of Ugandans. IRB (2005) 1.59
Disclosing a diagnosis of cancer: where and how does it occur? J Clin Oncol (2010) 1.57
Views of potential subjects toward proposed regulations for clinical research with adults unable to consent. Am J Psychiatry (2002) 1.55
Ethical considerations in HIV cure research: points to consider. Curr Opin HIV AIDS (2013) 1.55
Community health workers combat readmission. Arch Intern Med (2012) 1.51
Regional ethics organizations for protection of human research participants. Nat Med (2004) 1.48
Effects of once versus twice-daily parathyroid hormone 1-34 therapy in children with hypoparathyroidism. J Clin Endocrinol Metab (2008) 1.46
Biomarker-assisted dose selection for safety and efficacy in early development of PNU-100480 for tuberculosis. Antimicrob Agents Chemother (2010) 1.44
Long-term treatment of 12 children with chronic hypoparathyroidism: a randomized trial comparing synthetic human parathyroid hormone 1-34 versus calcitriol and calcium. J Clin Endocrinol Metab (2010) 1.44
Assessing the ethical and practical wisdom of surrogate consent for living organ donation. JAMA (2004) 1.40
Euthanasia and physician-assisted suicide: implications for physicians. J Clin Ethics (2004) 1.38
Respondent burden in clinical research: when are we asking too much of subjects? IRB (2005) 1.37
An analysis of U.S. practices of paying research participants. Contemp Clin Trials (2005) 1.37
Clinical characteristics of a cohort of 244 patients with congenital adrenal hyperplasia. J Clin Endocrinol Metab (2012) 1.36
Clinical research with economically disadvantaged populations. J Med Ethics (2007) 1.36
Too much glucagon, too little insulin: time course of pancreatic islet dysfunction in new-onset type 1 diabetes. Diabetes Care (2008) 1.36
Racial and ethnic differences in hospice use among patients with heart failure. Arch Intern Med (2010) 1.34
Does it pay to pay? A randomized trial of prepaid financial incentives and lottery incentives in surveys of nonphysician healthcare professionals. Nurs Res (2005) 1.32
Including persons with HIV infection in cancer clinical trials. J Clin Oncol (2008) 1.30
Money, coercion, and undue inducement: attitudes about payments to research participants. IRB (2012) 1.29
What should research participants understand to understand they are participants in research? Bioethics (2008) 1.27
Reciprocity and post-trial access for participants in antiretroviral therapy trials. AIDS (2006) 1.26
Utility of various functional and anatomic imaging modalities for detection of ectopic adrenocorticotropin-secreting tumors. J Clin Endocrinol Metab (2010) 1.24
Quality of parental consent in a Ugandan malaria study. Am J Public Health (2005) 1.19
Estimating population prevalence of posttraumatic stress disorder: an example using the PTSD checklist. J Trauma Stress (2008) 1.18
A pharmacokinetic and pharmacodynamic study of delayed- and extended-release hydrocortisone (Chronocort) vs. conventional hydrocortisone (Cortef) in the treatment of congenital adrenal hyperplasia. Clin Endocrinol (Oxf) (2009) 1.17
Blood pressure in pediatric patients with Cushing syndrome. J Clin Endocrinol Metab (2009) 1.16
Enrolling pregnant women: issues in clinical research. Womens Health Issues (2013) 1.13
Points to consider: The research ethics consultation service and the IRB. IRB (2009) 1.13
The quality of informed consent in a clinical research study in Thailand. IRB (2005) 1.13
Diagnostic experience among 4,334 women reporting surgically diagnosed endometriosis. Fertil Steril (2008) 1.11
Views of adolescents and parents on pediatric research without the potential for clinical benefit. Pediatrics (2012) 1.11
When to start ART in Africa. N Engl J Med (2013) 1.09
Macronodular adrenal hyperplasia due to mutations in an armadillo repeat containing 5 (ARMC5) gene: a clinical and genetic investigation. J Clin Endocrinol Metab (2014) 1.07
Planning for posttrial access to antiretroviral treatment for research participants in developing countries. Am J Public Health (2009) 1.06
Quality improvement and ethical oversight. Ann Intern Med (2007) 1.06
Use of adherence monitors as part of a team approach to control clonal spread of multidrug-resistant Acinetobacter baumannii in a research hospital. Infect Control Hosp Epidemiol (2011) 1.05
Relating pelvic pain location to surgical findings of endometriosis. Obstet Gynecol (2011) 1.05
Recovery of the hypothalamic-pituitary-adrenal axis in children and adolescents after surgical cure of Cushing's disease. J Clin Endocrinol Metab (2012) 1.03
Magnetic resonance imaging-guided volumetric ablation of symptomatic leiomyomata: correlation of imaging with histology. J Vasc Interv Radiol (2012) 1.02
Severe acute respiratory syndrome: providing care in the face of uncertainty. JAMA (2003) 1.01
Bioethical considerations of monoclonal B-cell lymphocytosis: donor transfer after haematopoietic stem cell transplantation. Br J Haematol (2007) 1.01
Return of chronic pelvic pain from endometriosis after raloxifene treatment: a randomized controlled trial. Obstet Gynecol (2008) 1.01
Misconceptions about coercion and undue influence: reflections on the views of IRB members. Bioethics (2012) 1.00
Rethinking the responsiveness requirement for international research. Lancet (2009) 1.00
Radioimmunoassay and tandem mass spectrometry measurement of bedtime salivary cortisol levels: a comparison of assays to establish hypercortisolism. J Clin Endocrinol Metab (2007) 1.00
Ethics of clinical research in the developing world. Nat Rev Immunol (2002) 0.99
Cancers, infections, and endocrine diseases in women with endometriosis. Fertil Steril (2009) 0.99
Specificity of screening tests for Cushing's syndrome in an overweight and obese population. J Clin Endocrinol Metab (2009) 0.98
Using location, color, size, and depth to characterize and identify endometriosis lesions in a cohort of 133 women. Fertil Steril (2007) 0.97
Does fear of retaliation deter requests for ethics consultation? Med Health Care Philos (2007) 0.96
Migraine in women with chronic pelvic pain with and without endometriosis. Fertil Steril (2010) 0.96
Randomization to standard and concise informed consent forms: development of evidence-based consent practices. Contemp Clin Trials (2012) 0.95
Nurse Practitioners' attitudes about cancer clinical trials and willingness to recommend research participation. Contemp Clin Trials (2011) 0.95
Post-trial access to tested interventions: the views of IRB/REC chair, investigators, and research participants in a multinational HIV/AIDS study. AIDS Res Hum Retroviruses (2006) 0.94
Psychiatric characterization of children with genetic causes of hyperandrogenism. Eur J Endocrinol (2010) 0.94
Conducting HIV research in racial and ethnic minority communities: building a successful interdisciplinary research team. J Assoc Nurses AIDS Care (2011) 0.94
Exploring decision-making of HIV-infected Hispanics and African Americans participating in clinical trials. J Assoc Nurses AIDS Care (2011) 0.93
Technical details influence the diagnostic accuracy of the 1 microg ACTH stimulation test. Eur J Endocrinol (2009) 0.93
A phase 2 study of Chronocort, a modified-release formulation of hydrocortisone, in the treatment of adults with classic congenital adrenal hyperplasia. J Clin Endocrinol Metab (2014) 0.93
"Special scrutiny": a targeted form of research protocol review. Ann Intern Med (2004) 0.92
Hypercortisolism is associated with increased coronary arterial atherosclerosis: analysis of noninvasive coronary angiography using multidetector computerized tomography. J Clin Endocrinol Metab (2013) 0.92
Effects of Cushing disease on bone mineral density in a pediatric population. J Pediatr (2010) 0.91
Financial incentives and response rates in nursing research. Nurs Res (2004) 0.91
Addressing the American health-care cost crisis: role of the oncology community. J Natl Cancer Inst (2013) 0.91
Circumcision and HIV prevention research: an ethical analysis. Lancet (2006) 0.90