Published in J Alzheimers Dis on January 01, 2010
Blood-brain barrier structure and function and the challenges for CNS drug delivery. J Inherit Metab Dis (2013) 1.62
The hCMEC/D3 cell line as a model of the human blood brain barrier. Fluids Barriers CNS (2013) 1.56
Blood-brain barrier dysfunction as a cause and consequence of Alzheimer's disease. J Cereb Blood Flow Metab (2013) 1.45
Dietary advanced glycation end products and aging. Nutrients (2010) 1.16
Lipopolysaccharide impairs amyloid β efflux from brain: altered vascular sequestration, cerebrospinal fluid reabsorption, peripheral clearance and transporter function at the blood-brain barrier. J Neuroinflammation (2012) 1.09
P-glycoprotein regulates blood-testis barrier dynamics via its effects on the occludin/zonula occludens 1 (ZO-1) protein complex mediated by focal adhesion kinase (FAK). Proc Natl Acad Sci U S A (2011) 1.05
Differences in amyloid-β clearance across mouse and human blood-brain barrier models: kinetic analysis and mechanistic modeling. Neuropharmacology (2014) 1.03
Obstructive sleep apnea and cognitive impairment: addressing the blood-brain barrier. Sleep Med Rev (2013) 0.91
Role of ABC transporters in the pathogenesis of Alzheimer's disease. ACS Chem Neurosci (2012) 0.90
In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use. J Cereb Blood Flow Metab (2016) 0.90
Metabolic Dysfunction of Astrocyte: An Initiating Factor in Beta-amyloid Pathology? Aging Neurodegener (2013) 0.86
Regulation of ABC efflux transporters at blood-brain barrier in health and neurological disorders. Brain Res (2015) 0.85
Alzheimer's and ABC transporters--new opportunities for diagnostics and treatment. Neurobiol Dis (2014) 0.85
Smuggling Drugs into the Brain: An Overview of Ligands Targeting Transcytosis for Drug Delivery across the Blood-Brain Barrier. Pharmaceutics (2014) 0.83
In vivo Differential Brain Clearance and Catabolism of Monomeric and Oligomeric Alzheimer's Aβ protein. Front Aging Neurosci (2016) 0.80
Antioxidants and Dementia Risk: Consideration through a Cerebrovascular Perspective. Nutrients (2016) 0.78
The role of the blood-brain barrier in the pathogenesis of senile plaques in Alzheimer's disease. Int J Alzheimers Dis (2014) 0.78
Geniposide Protects Primary Cortical Neurons against Oligomeric Aβ1-42-Induced Neurotoxicity through a Mitochondrial Pathway. PLoS One (2016) 0.76
Receptor for advanced glycation end products (RAGE) and its ligands: focus on spinal cord injury. Int J Mol Sci (2014) 0.75
Geniposide Alleviates Amyloid-Induced Synaptic Injury by Protecting Axonal Mitochondrial Trafficking. Front Cell Neurosci (2017) 0.75
Retinol (Vitamin A) Increases α-Synuclein, β-Amyloid Peptide, Tau Phosphorylation and RAGE Content in Human SH-SY5Y Neuronal Cell Line. Neurochem Res (2017) 0.75
Randomized, controlled, double-blind, cross-over trial assessing treatment preference for pazopanib versus sunitinib in patients with metastatic renal cell carcinoma: PISCES Study. J Clin Oncol (2014) 6.64
Modelling of the blood-brain barrier in drug discovery and development. Nat Rev Drug Discov (2007) 2.19
Temsirolimus and bevacizumab, or sunitinib, or interferon alfa and bevacizumab for patients with advanced renal cell carcinoma (TORAVA): a randomised phase 2 trial. Lancet Oncol (2011) 2.17
Underuse of oral anticoagulation for individuals with atrial fibrillation in a nursing home setting in France: comparisons of resident characteristics and physician attitude. J Am Geriatr Soc (2015) 2.04
Interaction of the RAGE cytoplasmic domain with diaphanous-1 is required for ligand-stimulated cellular migration through activation of Rac1 and Cdc42. J Biol Chem (2008) 1.97
Mouse syngenic in vitro blood-brain barrier model: a new tool to examine inflammatory events in cerebral endothelium. Lab Invest (2005) 1.92
Peroxisome proliferator-activated receptor-alpha activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment. J Neurosci (2003) 1.78
Mitochondrial dysfunction as an arrhythmogenic substrate: a translational proof-of-concept study in patients with metabolic syndrome in whom post-operative atrial fibrillation develops. J Am Coll Cardiol (2013) 1.53
Improved in vitro biocompatibility of bicarbonate-buffered peritoneal dialysis fluid. Perit Dial Int (2006) 1.44
Unusual short-term complete response to two regimens of cytotoxic chemotherapy in a patient with poorly differentiated thyroid carcinoma. J Clin Endocrinol Metab (2012) 1.42
Soluble receptor for advanced glycation end products: a new biomarker in diagnosis and prognosis of chronic inflammatory diseases. Rheumatology (Oxford) (2009) 1.36
Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis. Circulation (2005) 1.32
Differential roles for endothelial ICAM-1, ICAM-2, and VCAM-1 in shear-resistant T cell arrest, polarization, and directed crawling on blood-brain barrier endothelium. J Immunol (2010) 1.24
Oxygen glucose deprivation switches the transport of tPA across the blood-brain barrier from an LRP-dependent to an increased LRP-independent process. Stroke (2005) 1.18
Low-dose aspirin prevents age-related endothelial dysfunction in a mouse model of physiological aging. Am J Physiol Heart Circ Physiol (2008) 1.14
Mycobacterium tuberculosis heparin-binding haemagglutinin adhesin (HBHA) triggers receptor-mediated transcytosis without altering the integrity of tight junctions. Microbes Infect (2005) 1.13
Astrocyte mediated modulation of blood-brain barrier permeability does not correlate with a loss of tight junction proteins from the cellular contacts. Cell Tissue Res (2003) 1.09
P-glycoprotein in blood-brain barrier endothelial cells: interaction and oligomerization with caveolins. J Neurochem (2003) 1.07
High transcytosis of melanotransferrin (P97) across the blood-brain barrier. J Neurochem (2002) 1.07
Heterogeneous pattern of renal disease associated with homozygous factor H deficiency. Hum Pathol (2011) 1.00
Peroxisome-proliferator-activated receptor-alpha activation protects brain capillary endothelial cells from oxygen-glucose deprivation-induced hyperpermeability in the blood-brain barrier. Curr Neurovasc Res (2009) 1.00
Prediction of drug transport through the blood-brain barrier in vivo: a comparison between two in vitro cell models. Pharm Res (2002) 0.98
An in vitro blood-brain barrier model for high throughput (HTS) toxicological screening. Toxicol In Vitro (2008) 0.97
Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistance-associated proteins in an in vitro model of the blood-brain barrier. Brain Res (2004) 0.96
Physiological pathway for low-density lipoproteins across the blood-brain barrier: transcytosis through brain capillary endothelial cells in vitro. Endothelium (2008) 0.96
Overestimation of the probability of death on peritoneal dialysis by the Kaplan-Meier method: advantages of a competing risks approach. BMC Nephrol (2012) 0.95
Enlarging residual mass after treatment of a nonseminomatous germ cell tumor: growing teratoma syndrome or cancer recurrence? J Clin Oncol (2007) 0.94
Understanding the blood-brain barrier using gene and protein expression profiling technologies. Brain Res Rev (2009) 0.93
Inhibition of melanoma brain metastasis by targeting melanotransferrin at the cell surface. Pigment Cell Melanoma Res (2008) 0.92
Modelling the neurovascular unit and the blood-brain barrier with the unique function of pericytes. Curr Neurovasc Res (2011) 0.92
Carnitine: transport and physiological functions in the brain. Mol Aspects Med (2004) 0.90
An uncommon case of peritonitis: appendicitis should not be overlooked. Perit Dial Int (2007) 0.87
In vitro blood-brain barrier permeability and cerebral endothelial cell uptake of the neuroprotective nitrone compound NXY-059 in normoxic, hypoxic and ischemic conditions. Brain Res (2002) 0.87
Specific AHNAK expression in brain endothelial cells with barrier properties. J Cell Physiol (2005) 0.86
Evidence of lowest brain penetration of an antiemetic drug, metopimazine, compared to domperidone, metoclopramide and chlorpromazine, using an in vitro model of the blood-brain barrier. Pharmacol Res (2006) 0.86
Differential expression of selectins by mouse brain capillary endothelial cells in vitro in response to distinct inflammatory stimuli. Neurosci Lett (2005) 0.86
Endothelial cells and astrocytes: a concerto en duo in ischemic pathophysiology. Int J Cell Biol (2012) 0.86
AGEs, macrophage colony stimulating factor and vascular adhesion molecule blood levels are increased in patients with diabetic microangiopathy. Thromb Haemost (2004) 0.86
Actin, gelsolin and filamin-A are dynamic actors in the cytoskeleton remodelling contributing to the blood brain barrier phenotype. Proteomics (2009) 0.85
Truncated thioredoxin (Trx-80) promotes pro-inflammatory macrophages of the M1 phenotype and enhances atherosclerosis. J Cell Physiol (2013) 0.85
The MAP kinase pathway mediates transcytosis induced by TNF-alpha in an in vitro blood-brain barrier model. Eur J Neurosci (2005) 0.85
Transcriptional profiles of receptors and transporters involved in brain cholesterol homeostasis at the blood-brain barrier: use of an in vitro model. Brain Res (2008) 0.84
Brain pericytes from stress-susceptible pigs increase blood-brain barrier permeability in vitro. Fluids Barriers CNS (2012) 0.84
Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: an in vitro study. Brain Res (2009) 0.84
Influence of surface charge and inner composition of porous nanoparticles to cross blood-brain barrier in vitro. Int J Pharm (2007) 0.82
Localization of organic cation/carnitine transporter (OCTN2) in cells forming the blood-brain barrier. J Neurochem (2007) 0.81
Down-regulation of caveolin-1 in glioma vasculature: modulation by radiotherapy. J Neurosci Res (2004) 0.81
A large-scale electrophoresis- and chromatography-based determination of gene expression profiles in bovine brain capillary endothelial cells after the re-induction of blood-brain barrier properties. Proteome Sci (2010) 0.81
[3H]BHDP as a novel and selective ligand for sigma1 receptors in liver mitochondria and brain synaptosomes of the rat. FEBS Lett (2003) 0.81
Simplified percutaneous placement of peritoneal dialysis catheters: comparison with surgical placement. Perit Dial Int (2002) 0.81
Bexarotene Promotes Cholesterol Efflux and Restricts Apical-to-Basolateral Transport of Amyloid-β Peptides in an In Vitro Model of the Human Blood-Brain Barrier. J Alzheimers Dis (2015) 0.81
A simple method for assessing free brain/free plasma ratios using an in vitro model of the blood brain barrier. PLoS One (2013) 0.80
A differential proteomic approach identifies structural and functional components that contribute to the differentiation of brain capillary endothelial cells. J Proteomics (2011) 0.80
Effect of iodinated contrast agents on residual renal function in PD patients. Nephrol Dial Transplant (2005) 0.80
Intercommunications between brain capillary endothelial cells and glial cells increase the transcellular permeability of the blood-brain barrier during ischaemia. J Neurochem (2002) 0.80
Maternal calorie restriction modulates placental mitochondrial biogenesis and bioenergetic efficiency: putative involvement in fetoplacental growth defects in rats. Am J Physiol Endocrinol Metab (2012) 0.80
[Cognitive impairment and chronic kidney disease: which links?]. Nephrol Ther (2010) 0.80
Glial-cell-mediated re-induction of the blood-brain barrier phenotype in brain capillary endothelial cells: a differential gel electrophoresis study. Proteomics (2013) 0.80
Brain pericytes ABCA1 expression mediates cholesterol efflux but not cellular amyloid-β peptide accumulation. J Alzheimers Dis (2012) 0.80
Dietary CML-enriched protein induces functional arterial aging in a RAGE-dependent manner in mice. Mol Nutr Food Res (2015) 0.80
Metastatic renal cancer: evolution of five complete response cases after the antiangiogenic discontinuation. Bull Cancer (2011) 0.80
Pairwise comparison of 18F-FDG and 18F-FCH PET/CT in prostate cancer patients with rising PSA and known or suspected second malignancy. Nucl Med Commun (2016) 0.79
Amyloid-β peptides, Alzheimer's disease and the blood-brain barrier. Curr Alzheimer Res (2013) 0.79
Methylated beta-cyclodextrin as P-gp modulators for deliverance of doxorubicin across an in vitro model of blood-brain barrier. Bioorg Med Chem Lett (2006) 0.78
A systematic approach to managing pregnant dialysis patients--the importance of an intensified haemodiafiltration protocol. Nephrol Dial Transplant (2005) 0.78
Oxysterols decrease apical-to-basolateral transport of Aß peptides via an ABCB1-mediated process in an in vitro Blood-brain barrier model constituted of bovine brain capillary endothelial cells. Brain Res (2013) 0.78
Structural determination of the novel fragmentation routes of morphine opiate receptor antagonists using electrospray ionization quadrupole time-of-flight tandem mass spectrometry. Rapid Commun Mass Spectrom (2005) 0.78