Published in Pharmacogenomics on September 01, 2010
Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes: a parallel-group prospective cohort study in two sub-Saharan Africa populations. PLoS One (2013) 1.17
Pharmacogenetic & pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients. PLoS One (2011) 1.17
Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without tuberculosis: a prospective cohort study. BMC Infect Dis (2013) 1.00
Worldwide variation in human drug-metabolism enzyme genes CYP2B6 and UGT2B7: implications for HIV/AIDS treatment. Pharmacogenomics (2012) 0.93
PharmGKB summary: very important pharmacogene information for cytochrome P-450, family 2, subfamily A, polypeptide 6. Pharmacogenet Genomics (2012) 0.92
CYP2B6*6, CYP2B6*18, Body weight and sex are predictors of efavirenz pharmacokinetics and treatment response: population pharmacokinetic modeling in an HIV/AIDS and TB cohort in Zimbabwe. BMC Pharmacol Toxicol (2015) 0.92
Pharmacogenetic-based efavirenz dose modification: suggestions for an African population and the different CYP2B6 genotypes. PLoS One (2014) 0.87
Individualization of antiretroviral therapy. Pharmgenomics Pers Med (2011) 0.83
An Expanded Analysis of Pharmacogenetics Determinants of Efavirenz Response that Includes 3'-UTR Single Nucleotide Polymorphisms among Black South African HIV/AIDS Patients. Front Genet (2016) 0.81
Impact of UGT2B7 His268Tyr polymorphism on the outcome of adjuvant epirubicin treatment in breast cancer. Breast Cancer Res (2011) 0.79
PharmGKB summary: Efavirenz pathway, pharmacokinetics. Pharmacogenet Genomics (2015) 0.75
Genetic variants in CYP2B6 and CYP2A6 explain interindividual variation in efavirenz plasma concentrations of HIV-infected children with diverse ethnic origin. PLoS One (2017) 0.75
Respiratory toxicity of multi-wall carbon nanotubes. Toxicol Appl Pharmacol (2005) 4.25
The nanosilica hazard: another variable entity. Part Fibre Toxicol (2010) 2.38
Associations between cytomegalovirus infection and functional impairment and frailty in the BELFRAIL Cohort. J Am Geriatr Soc (2011) 2.38
Size-dependent cytotoxicity of monodisperse silica nanoparticles in human endothelial cells. Small (2009) 2.27
Preclinical evidence that sildenafil and vardenafil activate chloride transport in cystic fibrosis. Am J Respir Crit Care Med (2007) 2.18
Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock. Crit Care (2010) 2.11
The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients. Pharmacogenetics (2004) 2.06
Focusing the research efforts. Nat Nanotechnol (2012) 1.96
Absence of carcinogenic response to multiwall carbon nanotubes in a 2-year bioassay in the peritoneal cavity of the rat. Toxicol Sci (2009) 1.79
Platelet-derived growth factor-producing CD4+ Foxp3+ regulatory T lymphocytes promote lung fibrosis. Am J Respir Crit Care Med (2011) 1.78
The European Register of Specialists in Clinical Chemistry and Laboratory Medicine: guide to the Register, version 3-2010. Clin Chem Lab Med (2010) 1.68
Opportunities to optimize tacrolimus therapy in solid organ transplantation: report of the European consensus conference. Ther Drug Monit (2009) 1.68
A new functional CYP3A4 intron 6 polymorphism significantly affects tacrolimus pharmacokinetics in kidney transplant recipients. Clin Chem (2011) 1.64
Acute barium intoxication and hemodiafiltration. J Toxicol Clin Toxicol (2003) 1.55
Reactivity of carbon nanotubes: free radical generation or scavenging activity? Free Radic Biol Med (2005) 1.51
Vancomycin and ciprofloxacin: systemic antibiotic administration for peritoneal dialysis-associated peritonitis. Perit Dial Int (2004) 1.49
Donor age and ABCB1 1199G>A genetic polymorphism are independent factors affecting long-term renal function after kidney transplantation. J Surg Res (2012) 1.45
An HIV seroconversion case: unequal performance of combined antigen/antibodies assays. AIDS (2002) 1.45
IL-13 mediates in vivo IL-9 activities on lung epithelial cells but not on hematopoietic cells. J Immunol (2007) 1.44
Adverse health effects of child labor: high exposure to chromium and oxidative DNA damage in children manufacturing surgical instruments. Environ Health Perspect (2012) 1.44
Amplification-based DNA analysis in the diagnosis of prosthetic joint infection. J Mol Diagn (2008) 1.43
The impact of the assay for measuring albumin on corrected ('adjusted') calcium concentrations. Nephrol Dial Transplant (2009) 1.43
Cadmium, lung and prostate cancer: a systematic review of recent epidemiological data. J Toxicol Environ Health B Crit Rev (2003) 1.38
Prolonged unconsciousness in a patient on automated peritoneal dialysis. Eur J Emerg Med (2006) 1.38
Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: toxicological aspects. Chem Res Toxicol (2008) 1.32
Genetic polymorphisms in DNA repair genes and possible links with DNA repair rates, chromosomal aberrations and single-strand breaks in DNA. Carcinogenesis (2004) 1.28
Effect of a new functional CYP3A4 polymorphism on calcineurin inhibitors' dose requirements and trough blood levels in stable renal transplant patients. Pharmacogenomics (2011) 1.27
Pulmonary overexpression of IL-10 augments lung fibrosis and Th2 responses induced by silica particles. Am J Physiol Lung Cell Mol Physiol (2004) 1.27
Clastogenic and aneugenic effects of multi-wall carbon nanotubes in epithelial cells. Carcinogenesis (2008) 1.26
Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: physicochemical aspects. Chem Res Toxicol (2008) 1.26
Revisiting the loading dose of amikacin for patients with severe sepsis and septic shock. Crit Care (2010) 1.26
IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis. J Immunol (2010) 1.25
Markers of macrophage differentiation in experimental silicosis. J Leukoc Biol (2004) 1.23
Associations of urinary cadmium with age and urinary proteins: further evidence of physiological variations unrelated to metal accumulation and toxicity. Environ Health Perspect (2013) 1.22
CYP3A4*22: promising newly identified CYP3A4 variant allele for personalizing pharmacotherapy. Pharmacogenomics (2013) 1.21
Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids. Transplantation (2005) 1.21
Confounders in the assessment of the renal effects associated with low-level urinary cadmium: an analysis in industrial workers. Environ Health (2011) 1.21
Factors associated with presentation to care with advanced HIV disease in Brussels and Northern France: 1997-2007. BMC Infect Dis (2011) 1.18
The etiologic diagnosis of infectious discitis is improved by amplification-based DNA analysis. Arthritis Rheum (2004) 1.16
Azithromycin reduces spontaneous and induced inflammation in DeltaF508 cystic fibrosis mice. Respir Res (2006) 1.12
High human exposure to cobalt and other metals in Katanga, a mining area of the Democratic Republic of Congo. Environ Res (2009) 1.12
Cobalt and antimony: genotoxicity and carcinogenicity. Mutat Res (2003) 1.11
Potentiation of cyclophosphamide chemotherapy using the anti-angiogenic drug thalidomide: importance of optimal scheduling to exploit the 'normalization' window of the tumor vasculature. Cancer Lett (2006) 1.11
Azithromycin reduces exaggerated cytokine production by M1 alveolar macrophages in cystic fibrosis. Am J Respir Cell Mol Biol (2009) 1.11
A profibrotic function of IL-12p40 in experimental pulmonary fibrosis. J Immunol (2002) 1.11
Increased dioxin-like compounds in the serum of women with peritoneal endometriosis and deep endometriotic (adenomyotic) nodules. Fertil Steril (2005) 1.10
Thickness of multiwalled carbon nanotubes affects their lung toxicity. Chem Res Toxicol (2011) 1.10
Influence of size, surface area and microporosity on the in vitro cytotoxic activity of amorphous silica nanoparticles in different cell types. Nanotoxicology (2010) 1.10
The new CYP3A4 intron 6 C>T polymorphism (CYP3A4*22) is associated with an increased risk of delayed graft function and worse renal function in cyclosporine-treated kidney transplant patients. Pharmacogenet Genomics (2012) 1.09
Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: A review. Clin Biochem (2010) 1.09
Novel CYP3A4 intron 6 single nucleotide polymorphism is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study. Pharmacogenet Genomics (2011) 1.09
Synthesis and characterization of stable monodisperse silica nanoparticle sols for in vitro cytotoxicity testing. Langmuir (2010) 1.06
Environmental and host-associated risk factors in endometriosis and deep endometriotic nodules: a matched case-control study. Environ Res (2006) 1.06
The threshold level of urinary cadmium associated with increased urinary excretion of retinol-binding protein and beta 2-microglobulin: a re-assessment in a large cohort of nickel-cadmium battery workers. Occup Environ Med (2010) 1.05
Profibrotic effect of IL-9 overexpression in a model of airway remodeling. Am J Respir Cell Mol Biol (2007) 1.05
Acute liver failure with renal impairment related to the abuse of senna anthraquinone glycosides. Ann Pharmacother (2005) 1.04
Review and meta-analysis of risk estimates for prostate cancer in pesticide manufacturing workers. Cancer Causes Control (2006) 1.04
Comparison of calibrated chromogenic anti-Xa assay and PT tests with LC-MS/MS for the therapeutic monitoring of patients treated with rivaroxaban. Thromb Haemost (2013) 1.02
The BELFRAIL (BFC80+) study: a population-based prospective cohort study of the very elderly in Belgium. BMC Geriatr (2010) 1.01
Basic protocol for transepithelial nasal potential difference measurements. J Cyst Fibros (2004) 1.01
Validation of an ELISA-based screening assay for the detection of amphetamine, MDMA and MDA in blood and oral fluid. Forensic Sci Int (2005) 1.01
Towards predicting the lung fibrogenic activity of nanomaterials: experimental validation of an in vitro fibroblast proliferation assay. Part Fibre Toxicol (2013) 1.00
Overexpression of cathepsin K during silica-induced lung fibrosis and control by TGF-beta. Respir Res (2005) 1.00
The EC4 European syllabus for post-graduate training in clinical chemistry and laboratory medicine: version 4--2012. Clin Chem Lab Med (2012) 0.99
A systematic review of myeloid leukemias and occupational pesticide exposure. Cancer Causes Control (2007) 0.97
Streptococcus gordonii septic arthritis: two cases and review of literature. BMC Infect Dis (2012) 0.97
Markers of individual susceptibility and DNA repair rate in workers exposed to xenobiotics in a tire plant. Environ Mol Mutagen (2004) 0.95
Occupational exposure to pesticides and Parkinson's disease: a systematic review and meta-analysis of cohort studies. Environ Int (2012) 0.95
Lung and systemic responses to carbon nanotubes (CNT) in mice. Toxicol Sci (2007) 0.95
Residential exposure to pesticides and childhood leukaemia: a systematic review and meta-analysis. Environ Int (2011) 0.95
Adherence to screening guidelines for hepatitis C among HIV-positive patients. AIDS Patient Care STDS (2013) 0.94
The role of pro- and anti-inflammatory responses in silica-induced lung fibrosis. Respir Res (2005) 0.94
Limited sampling models and Bayesian estimation for mycophenolic acid area under the curve prediction in stable renal transplant patients co-medicated with ciclosporin or sirolimus. Clin Pharmacokinet (2009) 0.94
A simultaneous d-optimal designed study for population pharmacokinetic analyses of mycophenolic Acid and tacrolimus early after renal transplantation. J Clin Pharmacol (2011) 0.93
Vancomycin penetration of uninfected pleural fluid exudate after continuous or intermittent infusion. Antimicrob Agents Chemother (2003) 0.93
Reference values and upper reference limits for 26 trace elements in the urine of adults living in Belgium. Clin Chem Lab Med (2013) 0.93
An overview of monitoring and supplementation of omega 3 fatty acids in cystic fibrosis. Clin Biochem (2007) 0.93
Prevalence and epidemiology of HIV type 1 drug resistance among newly diagnosed therapy-naive patients in Belgium from 2003 to 2006. AIDS Res Hum Retroviruses (2008) 0.92
Elevated blood lead levels and sources of exposure in the population of Kinshasa, the capital of the Democratic Republic of Congo. J Expo Sci Environ Epidemiol (2012) 0.92
1199G>A and 2677G>T/A polymorphisms of ABCB1 independently affect tacrolimus concentration in hepatic tissue after liver transplantation. Pharmacogenet Genomics (2007) 0.92
Time of drug administration, CYP3A5 and ABCB1 genotypes, and analytical method influence tacrolimus pharmacokinetics: a population pharmacokinetic study. Ther Drug Monit (2009) 0.91
Characterization of the effect of interleukin-10 on silica-induced lung fibrosis in mice. Am J Respir Cell Mol Biol (2004) 0.91
Plasma and tissue determination of 4-methylpyrazole for pharmacokinetic analysis in acute adult and pediatric methanol/ethylene glycol poisoning. Ther Drug Monit (2004) 0.91
The cytotoxic activity of amorphous silica nanoparticles is mainly influenced by surface area and not by aggregation. Toxicol Lett (2011) 0.91
Evaluation of the apoptogenic potential of hard metal dust (WC-Co), tungsten carbide and metallic cobalt. Toxicol Lett (2004) 0.91