PubRank

Shridar Ganesan

Author PubWeight™ 82.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev 2005 12.15
2 X chromosomal abnormalities in basal-like human breast cancer. Cancer Cell 2006 7.17
3 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. Nat Struct Mol Biol 2010 5.59
4 Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer. J Clin Oncol 2010 5.50
5 Molecular Stratification of Clear Cell Renal Cell Carcinoma by Consensus Clustering Reveals Distinct Subtypes and Survival Patterns. Genes Cancer 2010 3.78
6 Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors. Cancer Discov 2012 2.74
7 Computerized image-based detection and grading of lymphocytic infiltration in HER2+ breast cancer histopathology. IEEE Trans Biomed Eng 2009 2.56
8 Expectation-maximization-driven geodesic active contour with overlap resolution (EMaGACOR): application to lymphocyte segmentation on breast cancer histopathology. IEEE Trans Biomed Eng 2010 2.52
9 Identifying mRNA targets of microRNA dysregulated in cancer: with application to clear cell Renal Cell Carcinoma. BMC Syst Biol 2010 2.49
10 High expression of lymphocyte-associated genes in node-negative HER2+ breast cancers correlates with lower recurrence rates. Cancer Res 2007 2.48
11 Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer. J Clin Invest 2012 2.03
12 The telomerase reverse transcriptase regulates chromatin state and DNA damage responses. Proc Natl Acad Sci U S A 2005 2.01
13 Active localization of the retinoblastoma protein in chromatin and its response to S phase DNA damage. Mol Cell 2003 1.55
14 BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair. Mol Cell Biol 2011 1.52
15 Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer. Cancer Discov 2013 1.32
16 PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function. Mol Cell Biol 2012 1.30
17 The disappearing Barr body in breast and ovarian cancers. Nat Rev Cancer 2007 1.24
18 Portraits of breast cancer progression. BMC Bioinformatics 2007 1.17
19 Further evidence for BRCA1 communication with the inactive X chromosome. Cell 2007 1.15
20 Mutational landscape of the essential autophagy gene BECN1 in human cancers. Mol Cancer Res 2014 1.13
21 Association of nuclear localization of a long interspersed nuclear element-1 protein in breast tumors with poor prognostic outcomes. Genes Cancer 2010 1.12
22 UHRF1 depletion causes a G2/M arrest, activation of DNA damage response and apoptosis. Biochem J 2011 1.11
23 Computer-assisted assessment of the human epidermal growth factor receptor 2 immunohistochemical assay in imaged histologic sections using a membrane isolation algorithm and quantitative analysis of positive controls. BMC Med Imaging 2008 1.11
24 Amplified loci on chromosomes 8 and 17 predict early relapse in ER-positive breast cancers. PLoS One 2012 1.10
25 Towards improved cancer diagnosis and prognosis using analysis of gene expression data and computer aided imaging. Exp Biol Med (Maywood) 2009 1.05
26 BRCA1, PARP, and 53BP1: conditional synthetic lethality and synthetic viability. J Mol Cell Biol 2011 1.02
27 Bcl-2 modulation to activate apoptosis in prostate cancer. Mol Cancer Res 2009 1.01
28 A 2D mechanistic model of breast ductal carcinoma in situ (DCIS) morphology and progression. J Theor Biol 2009 0.96
29 Multi-field-of-view strategy for image-based outcome prediction of multi-parametric estrogen receptor-positive breast cancer histopathology: Comparison to Oncotype DX. J Pathol Inform 2012 0.95
30 Lactase persistence and lipid pathway selection in the Maasai. PLoS One 2012 0.95
31 Low p53 binding protein 1 (53BP1) expression is associated with increased local recurrence in breast cancer patients treated with breast-conserving surgery and radiotherapy. Int J Radiat Oncol Biol Phys 2012 0.93
32 Multi-field-of-view framework for distinguishing tumor grade in ER+ breast cancer from entire histopathology slides. IEEE Trans Biomed Eng 2013 0.93
33 Tripartite Motif-containing 33 (TRIM33) protein functions in the poly(ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver Cancer 1 (ALC1) protein. J Biol Chem 2013 0.89
34 Triple-negative breast cancer: molecular subtypes and targeted therapy. Curr Opin Obstet Gynecol 2014 0.89
35 ErbB2, EphrinB1, Src kinase and PTPN13 signaling complex regulates MAP kinase signaling in human cancers. PLoS One 2012 0.87
36 Breast cancer stratification from analysis of micro-array data of micro-dissected specimens. Genome Inform 2007 0.83
37 Identification of the YES1 Kinase as a Therapeutic Target in Basal-Like Breast Cancers. Genes Cancer 2010 0.83
38 Metabotropic glutamate receptor 1 expression and its polymorphic variants associate with breast cancer phenotypes. PLoS One 2013 0.81
39 Metabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells. Breast Cancer Res Treat 2015 0.80
40 ERG and CHD1 heterogeneity in prostate cancer: use of confocal microscopy in assessment of microscopic foci. Prostate 2014 0.79
41 Evaluation of single nucleotide polymorphisms (SNPs) in the p53 binding protein 1 (TP53BP1) gene in breast cancer patients treated with breast-conserving surgery and whole-breast irradiation (BCS + RT). Int J Radiat Oncol Biol Phys 2010 0.79
42 Deficiency of the dual ubiquitin/SUMO ligase Topors results in genetic instability and an increased rate of malignancy in mice. BMC Mol Biol 2010 0.79
43 Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer. J Clin Invest 2016 0.77
44 Automated reconstruction algorithm for identification of 3D architectures of cribriform ductal carcinoma in situ. PLoS One 2012 0.75
45 Clinicopathologic presentation of Asian-Indian American (AIA) women with stage 0, I & II breast cancer. J Immigr Minor Health 2011 0.75
46 A novel role of chromodomain protein CBX8 in DNA damage response. J Biol Chem 2017 0.75