Published in Nanomedicine (Lond) on September 01, 2010
Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers. Nucleic Acids Res (2012) 1.47
Cellular uptake and intracellular trafficking of antisense and siRNA oligonucleotides. Bioconjug Chem (2011) 1.32
Current progress on aptamer-targeted oligonucleotide therapeutics. Ther Deliv (2013) 1.09
Multivalent cyclic RGD conjugates for targeted delivery of small interfering RNA. Bioconjug Chem (2011) 0.99
The chemistry and biology of oligonucleotide conjugates. Acc Chem Res (2012) 0.95
Cellular uptake and intracellular trafficking of oligonucleotides: implications for oligonucleotide pharmacology. Nucleic Acid Ther (2014) 0.90
High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides. Nucleic Acids Res (2015) 0.86
Multi-armed cationic cyclodextrin:poly(ethylene glycol) polyrotaxanes as efficient gene silencing vectors. Integr Biol (Camb) (2013) 0.85
Cellular uptake and intracellular trafficking of oligonucleotides. Adv Drug Deliv Rev (2015) 0.83
Conjugation with receptor-targeted histidine-rich peptides enhances the pharmacological effectiveness of antisense oligonucleotides. Bioconjug Chem (2013) 0.83
Bioconjugates for targeted delivery of therapeutic oligonucleotides. Adv Drug Deliv Rev (2015) 0.83
Small interfering RNAs targeting cyclin D1 and cyclin D2 enhance the cytotoxicity of chemotherapeutic agents in mantle cell lymphoma cell lines. Leuk Lymphoma (2011) 0.80
A glucose carbonate apatite complex exhibits in vitro and in vivo anti-tumour effects. Sci Rep (2015) 0.77
Imaging mRNA expression levels in living cells with PNA·DNA binary FRET probes delivered by cationic shell-crosslinked nanoparticles. Org Biomol Chem (2013) 0.76
Selection of the most potent specific on/off adaptor-hepatitis delta virus ribozymes for use in gene targeting. Nucleic Acid Ther (2011) 0.76
Self-Amplifying Replicon RNA Vaccine Delivery to Dendritic Cells by Synthetic Nanoparticles. Vaccines (Basel) (2014) 0.75
Nanoformulation of D-α-tocopheryl polyethylene glycol 1000 succinate-b-poly(ε-caprolactone-ran-glycolide) diblock copolymer for siRNA targeting HIF-1α for nasopharyngeal carcinoma therapy. Int J Nanomedicine (2015) 0.75
Innovative delivery of siRNA to solid tumors by super carbonate apatite. PLoS One (2015) 0.75
PEGylated nanoparticles for biological and pharmaceutical applications. Adv Drug Deliv Rev (2003) 3.19
Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells. J Am Chem Soc (2005) 1.66
pH-responsive three-layered PEGylated polyplex micelle based on a lactosylated ABC triblock copolymer as a targetable and endosome-disruptive nonviral gene vector. Bioconjug Chem (2006) 1.24
Two-dimensional multiarray formation of hepatocyte spheroids on a microfabricated PEG-brush surface. Chembiochem (2004) 1.12
Systemic delivery of siRNA to tumors using a lipid nanoparticle containing a tumor-specific cleavable PEG-lipid. Biomaterials (2011) 1.09
A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo. J Control Release (2009) 1.06
A core-shell-type fluorescent nanosphere possessing reactive poly(ethylene glycol) tethered chains on the surface for zeptomole detection of protein in time-resolved fluorometric immunoassay. Anal Chem (2003) 1.04
Preparation of a novel PEG-clay hybrid as a DDS material: dispersion stability and sustained release profiles. J Control Release (2005) 0.99
Design of poly(ethylene glycol)/streptavidin coimmobilized upconversion nanophosphors and their application to fluorescence biolabeling. Langmuir (2008) 0.97
An orally administered redox nanoparticle that accumulates in the colonic mucosa and reduces colitis in mice. Gastroenterology (2012) 0.95
Nanospheres for DNA separation chips. Nat Biotechnol (2004) 0.95
Enhanced growth inhibition of hepatic multicellular tumor spheroids by lactosylated poly(ethylene glycol)-siRNA conjugate formulated in PEGylated polyplexes. ChemMedChem (2007) 0.94
Lactose-installed poly(ethylene glycol)-poly(d,l-lactide) block copolymer micelles exhibit fast-rate binding and high affinity toward a protein bed simulating a cell surface. A surface plasmon resonance study. Bioconjug Chem (2003) 0.93
Ligand density effect on biorecognition by PEGylated gold nanoparticles: regulated interaction of RCA120 lectin with lactose installed to the distal end of tethered PEG strands on gold surface. Biomacromolecules (2005) 0.93
Direct observation of adsorption-induced inactivation of antibody fragments surrounded by mixed-PEG layer on a gold surface. J Am Chem Soc (2010) 0.93
Intracellular inducible alkylation system that exhibits antisense effects with greater potency and selectivity than the natural oligonucleotide. Angew Chem Int Ed Engl (2006) 0.93
Temperature-related change in the properties relevant to drug delivery of poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles in aqueous milieu. J Control Release (2002) 0.92
Density control of poly(ethylene glycol) layer to regulate cellular attachment. Langmuir (2007) 0.91
pH-sensitive radical-containing-nanoparticle (RNP) for the L-band-EPR imaging of low pH circumstances. Bioconjug Chem (2009) 0.91
On-off regulation of 19F magnetic resonance signals based on pH-sensitive PEGylated nanogels for potential tumor-specific smart 19F MRI probes. Bioconjug Chem (2007) 0.89
Enhanced cytoplasmic delivery of siRNA using a stabilized polyion complex based on PEGylated nanogels with a cross-linked polyamine structure. Biomacromolecules (2009) 0.89
pH-responsive oligodeoxynucleotide (ODN)-poly(ethylene glycol) conjugate through acid-labile beta-thiopropionate linkage: preparation and polyion complex micelle formation. Biomacromolecules (2003) 0.89
Redox nanoparticle treatment protects against neurological deficit in focused ultrasound-induced intracerebral hemorrhage. Nanomedicine (Lond) (2012) 0.88
Newly synthesized radical-containing nanoparticles enhance neuroprotection after cerebral ischemia-reperfusion injury. Neurosurgery (2011) 0.88
Inverted pattern formation of cell microarrays on poly(ethylene glycol) (PEG) gel patterned surface and construction of hepatocyte spheroids on unmodified PEG gel microdomains. Lab Chip (2009) 0.87
Smart polymeric micelles as nanocarriers for oligonucleotides and siRNA delivery. Nucleic Acids Symp Ser (Oxf) (2005) 0.87
Supramolecular assemblies for the cytoplasmic delivery of antisense oligodeoxynucleotide: polyion complex (PIC) micelles based on poly(ethylene glycol)-SS-oligodeoxynucleotide conjugate. Biomacromolecules (2005) 0.87
Polyion complex micelles of pDNA with acetal-poly(ethylene glycol)-poly(2-(dimethylamino)ethyl methacrylate) block copolymer as the gene carrier system: physicochemical properties of micelles relevant to gene transfection efficacy. Biomacromolecules (2004) 0.85
The ROS scavenging and renal protective effects of pH-responsive nitroxide radical-containing nanoparticles. Biomaterials (2011) 0.85
Design of core--shell-type nanoparticles carrying stable radicals in the core. Biomacromolecules (2009) 0.84
Efficient short interference RNA delivery to tumor cells using a combination of octaarginine, GALA and tumor-specific, cleavable polyethylene glycol system. Biol Pharm Bull (2009) 0.84
Smart polyion complex micelles for targeted intracellular delivery of PEGylated antisense oligonucleotides containing acid-labile linkages. Chembiochem (2005) 0.84
Block ionomer complexes of PEG-block-poly(4-vinylbenzylphosphonate) and cationic surfactants as highly stable, pH responsive drug delivery system. J Control Release (2012) 0.84
Suppression of NSAID-induced small intestinal inflammation by orally administered redox nanoparticles. Biomaterials (2013) 0.83
A high-performance waveguide-mode biosensor for detection of factor IX using PEG-based blocking agents to suppress non-specific binding and improve sensitivity. Analyst (2013) 0.83
Thermal characterization of poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles based on pyrene excimer formation. J Control Release (2004) 0.83
Near-infrared (1550 nm) in vivo bioimaging based on rare-earth doped ceramic nanophosphors modified with PEG-b-poly(4-vinylbenzylphosphonate). Nanoscale (2011) 0.82
In vitro and in vivo characteristics of core-shell type nanogel particles: optimization of core cross-linking density and surface poly(ethylene glycol) density in PEGylated nanogels. Acta Biomater (2011) 0.82
Creation of a mixed poly(ethylene glycol) tethered-chain surface for preventing the nonspecific adsorption of proteins and peptides. Biointerphases (2007) 0.81
Completely dispersible PEGylated gold nanoparticles under physiological conditions: modification of gold nanoparticles with precisely controlled PEG-b-polyamine. Langmuir (2008) 0.81
Lactose-conjugated polyion complex micelles incorporating plasmid DNA as a targetable gene vector system: their preparation and gene transfecting efficiency against cultured HepG2 cells. J Control Release (2004) 0.81
Nitroxyl radical-containing nanoparticles for novel nanomedicine against oxidative stress injury. Nanomedicine (Lond) (2011) 0.81
Spheroid array of fetal mouse liver cells constructed on a PEG-gel micropatterned surface: upregulation of hepatic functions by co-culture with nonparenchymal liver cells. Lab Chip (2009) 0.81
Glycolytic enzymes PGK1 and PKM2 as novel transcriptional targets of PPARγ in breast cancer pathophysiology. J Drug Target (2012) 0.81
Characterization of aldehyde-PEG tethered surfaces: influence of PEG chain length on the specific biorecognition. Langmuir (2004) 0.80
Different mechanisms of action of poly(ethylene glycol) and arginine on thermal inactivation of lysozyme and ribonuclease A. Biotechnol Bioeng (2012) 0.80
The use of nitroxide radical-containing nanoparticles coupled with piperine to protect neuroblastoma SH-SY5Y cells from Aβ-induced oxidative stress. Biomaterials (2011) 0.80
Chemical nanotherapy: nitroxyl radical-containing nanoparticle protects neuroblastoma SH-SY5Y cells from Abeta-induced oxidative stress. Ther Deliv (2011) 0.80
Efficient siRNA delivery based on PEGylated and partially quaternized polyamine nanogels: enhanced gene silencing activity by the cooperative effect of tertiary and quaternary amino groups in the core. J Control Release (2010) 0.80
Co-immobilized poly(ethylene glycol)-block-polyamines promote sensitivity and restrict biofouling on gold sensor surface for detecting factor IX in human plasma. Analyst (2014) 0.80
Non-Fouling Character of Poly[2-(methacryloyloxy)ethyl Phosphorylcholine]-Modified Gold Surfaces Fabricated by the 'Grafting to' Method: Comparison of its Protein Resistance with Poly(ethylene glycol)-Modified Gold Surfaces. Macromol Rapid Commun (2009) 0.79
Development of silica-containing redox nanoparticles for medical applications. Biomater Sci (2015) 0.79
Preparation of highly dispersible and tumor-accumulative, iron oxide nanoparticles Multi-point anchoring of PEG-b-poly(4-vinylbenzylphosphonate) improves performance significantly. Colloids Surf B Biointerfaces (2011) 0.79
Creation of a blood-compatible surface: a novel strategy for suppressing blood activation and coagulation using a nitroxide radical-containing polymer with reactive oxygen species scavenging activity. Acta Biomater (2011) 0.79
Reactive oxygen species-scavenging nanomedicines for the treatment of oxidative stress injuries. Adv Healthc Mater (2014) 0.79
Structure and activity assay of nanozymes prepared by the coimmobilization of practically useful enzymes and hydrophilic block copolymers on gold nanoparticles. Langmuir (2008) 0.79
Electric stimulus opens intercellular spaces in skin. J Biol Chem (2013) 0.78
High-performance immunolatex possessing a mixed-PEG/antibody coimmobilized surface: highly sensitive ferritin immunodiagnostics. Anal Chem (2009) 0.78
Synthesis of heterotelechelic poly(ethylene glycol) derivatives having alpha-benzaldehyde and omega-pyridyl disulfide groups by ring opening polymerization of ethylene oxide using 4-(diethoxymethyl)benzyl alkoxide as a novel initiator. Bioconjug Chem (2004) 0.78
Large payloads of gold nanoparticles into the polyamine network core of stimuli-responsive PEGylated nanogels for selective and noninvasive cancer photothermal therapy. Nanoscale (2010) 0.78
Long-term survival and functional maintenance of hepatocytes by using a microfabricated cell array. Colloids Surf B Biointerfaces (2012) 0.77
Coffee component hydroxyl hydroquinone (HHQ) as a putative ligand for PPAR gamma and implications in breast cancer. BMC Genomics (2013) 0.77
Redox nanoparticle therapeutics to cancer--increase in therapeutic effect of doxorubicin, suppressing its adverse effect. J Control Release (2013) 0.77
Redox-active injectable gel using thermo-responsive nanoscale polyion complex flower micelle for noninvasive treatment of local inflammation. J Control Release (2013) 0.77
Tumor growth suppression by gadolinium-neutron capture therapy using gadolinium-entrapped liposome as gadolinium delivery agent. Biomed Pharmacother (2012) 0.77
Pharmacokinetics of core-polymerized, boron-conjugated micelles designed for boron neutron capture therapy for cancer. Biomaterials (2012) 0.77
High-performance surface acoustic wave immunosensing system on a PEG/aptamer hybridized surface. Langmuir (2013) 0.77
Regulation of lysozyme activity based on thermotolerant protein/smart polymer complex formation. J Am Chem Soc (2009) 0.76
High PEGylation efficiency of pentaethylenehexamine-end poly(ethylene glycol) (mPEG-N6) for active-ester surface. Colloids Surf B Biointerfaces (2011) 0.76
A design of nanosized PEGylated-latex mixed polymer solution for microchip electrophoresis. Lab Chip (2004) 0.76
Improved complementary polymer pair system: switching for enzyme activity by PEGylated polymers. Langmuir (2012) 0.76
Stimuli-responsive smart nanogels for cancer diagnostics and therapy. Nanomedicine (Lond) (2010) 0.76
Development of a high-performance immunolatex based on "soft landing" antibody immobilization mechanism. Colloids Surf B Biointerfaces (2011) 0.75
Fluorescence-based affinity labeling of nucleobase by hydrogen-bond forming metal complex. Nucleic Acids Symp Ser (Oxf) (2007) 0.75
Oral nanotherapeutics: effect of redox nanoparticle on microflora in mice with dextran sodium sulfate-induced colitis. J Gastroenterol (2013) 0.75
Indomethacin-loaded redox nanoparticles improve oral bioavailability of indomethacin and suppress its small intestinal inflammation. Ther Deliv (2014) 0.75
Physicochemical characterization of densely packed poly(ethylene glycol) layer for minimizing nonspecific protein adsorption. J Nanosci Nanotechnol (2007) 0.75
Colloidal Au replacement assay for highly sensitive quantification of low molecular weight analytes by surface plasmon resonance. Bioconjug Chem (2007) 0.75
Design and preparation of a nanoprobe for imaging inflammation sites. Biointerphases (2012) 0.75
Efficient inhibition of interfacial nonspecific interaction to create practically utilizable high ferritin-response immunolatex. Anal Chem (2009) 0.75
Synthesis and evaluation of the functional oligonucleotides-PEG conjugates. Nucleic Acids Symp Ser (Oxf) (2004) 0.75
Novel oligonucleotide carrier as scavenger for reactive oxygen species. Macromol Biosci (2010) 0.75
Binding enhancement of antigen-functionalized PEGylated gold nanoparticles onto antibody-immobilized surface by increasing the functionalized antigen using alpha-sulfanyl-omega-amino-PEG. Chem Commun (Camb) (2008) 0.75
TEMPOL protects human neuroblastoma SH-SY5Y cells against β-amyloid-induced cell toxicity. Eur J Pharmacol (2010) 0.75
Simple solid-phase synthesis and biological properties of carbohydrate-oligonucleotide conjugates modified at the 3'-terminus. Bioconjug Chem (2010) 0.75
Novel protein PEGylation chemistry via glutalaldehyde-functionalized PEG. Bioconjug Chem (2013) 0.75
Novel biocompatible nanoreactor for silica/gold hybrid nanoparticles preparation. Colloids Surf B Biointerfaces (2012) 0.75
Improving the heat resistance of ribonuclease A by the addition of poly(N,N-diethylaminoethyl methacrylate)-graft-poly(ethylene glycol) (PEAMA-g-PEG). Macromol Biosci (2010) 0.75
Silica-installed redox nanoparticles for novel oral nanotherapeutics - improvement in intestinal delivery with anti-inflammatory effects. J Drug Target (2014) 0.75