Published in Stem Cells on November 01, 2010
Hydrogel design for cartilage tissue engineering: a case study with hyaluronic acid. Biomaterials (2011) 1.40
Mesenchymal stem cells for cartilage repair in osteoarthritis. Stem Cell Res Ther (2012) 1.26
SOX9 gene transfer via safe, stable, replication-defective recombinant adeno-associated virus vectors as a novel, powerful tool to enhance the chondrogenic potential of human mesenchymal stem cells. Stem Cell Res Ther (2012) 1.06
Cell Therapy and Tissue Engineering Approaches for Cartilage Repair and/or Regeneration. Int J Stem Cells (2015) 0.96
Subchondral bone influences chondrogenic differentiation and collagen production of human bone marrow-derived mesenchymal stem cells and articular chondrocytes. Arthritis Res Ther (2014) 0.92
Time-dependent processes in stem cell-based tissue engineering of articular cartilage. Stem Cell Rev (2012) 0.92
Stem cell application for osteoarthritis in the knee joint: A minireview. World J Stem Cells (2014) 0.87
Changes of chondrocyte expression profiles in human MSC aggregates in the presence of PEG microspheres and TGF-β3. Biomaterials (2011) 0.86
Toward regeneration of articular cartilage. Birth Defects Res C Embryo Today (2013) 0.85
Sox9 potentiates BMP2-induced chondrogenic differentiation and inhibits BMP2-induced osteogenic differentiation. PLoS One (2014) 0.85
miRNA Control of Tissue Repair and Regeneration. Am J Pathol (2015) 0.83
Maximizing phenotype constraint and extracellular matrix production in primary human chondrocytes using arginine-glycine-aspartate concentration gradient hydrogels. Acta Biomater (2013) 0.83
Regeneration of articular cartilage in healer and non-healer mice. Matrix Biol (2014) 0.82
Roles of microRNAs in prenatal chondrogenesis, postnatal chondrogenesis and cartilage-related diseases. J Cell Mol Med (2013) 0.81
Enzymatically cross-linked alginic-hyaluronic acid composite hydrogels as cell delivery vehicles. Int J Biol Macromol (2013) 0.81
ECM production of primary human and bovine chondrocytes in hybrid PEG hydrogels containing type I collagen and hyaluronic acid. Biomacromolecules (2012) 0.80
Radiation-induced alterations of osteogenic and chondrogenic differentiation of human mesenchymal stem cells. PLoS One (2015) 0.77
Photocrosslinked layered gelatin-chitosan hydrogel with graded compositions for osteochondral defect repair. J Mater Sci Mater Med (2015) 0.77
Transient vascularization of transplanted human adult-derived progenitors promotes self-organizing cartilage. J Clin Invest (2014) 0.75
Bilayer Implants: Electromechanical Assessment of Regenerated Articular Cartilage in a Sheep Model. Cartilage (2016) 0.75
Three-Dimensional Bioprinting and Its Potential in the Field of Articular Cartilage Regeneration. Cartilage (2016) 0.75
Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg Am (2007) 24.18
Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med (1994) 14.46
Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg Am (1971) 9.93
The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells. Cell Tissue Kinet (1970) 7.16
HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. Exp Hematol (2003) 5.35
Multipotent mesenchymal stem cells from adult human synovial membrane. Arthritis Rheum (2001) 4.57
Two- to 9-year outcome after autologous chondrocyte transplantation of the knee. Clin Orthop Relat Res (2000) 3.34
Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay. J Clin Invest (1994) 3.30
The surface of articular cartilage contains a progenitor cell population. J Cell Sci (2004) 3.28
Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration. J Clin Invest (1995) 2.67
Variations in the intrinsic mechanical properties of human articular cartilage with age, degeneration, and water content. J Bone Joint Surg Am (1982) 2.57
In vivo engineering of organs: the bone bioreactor. Proc Natl Acad Sci U S A (2005) 2.04
The role of mesenchymal stem cells in haemopoiesis. Blood Rev (2005) 1.98
Total knee replacement: is it really an effective procedure for all? Knee (2007) 1.78
Principles of cartilage repair and regeneration. Clin Orthop Relat Res (1997) 1.75
Articular cartilage repair: are the intrinsic biological constraints undermining this process insuperable? Osteoarthritis Cartilage (1999) 1.69
Human articular chondrocytes secrete parathyroid hormone-related protein and inhibit hypertrophy of mesenchymal stem cells in coculture during chondrogenesis. Arthritis Rheum (2010) 1.64
The basic science of the subchondral bone. Knee Surg Sports Traumatol Arthrosc (2010) 1.55
The development of articular cartilage: evidence for an appositional growth mechanism. Anat Embryol (Berl) (2001) 1.54
Nucleostemin is a marker of proliferating stromal stem cells in adult human bone marrow. Stem Cells (2005) 1.49
The natural history of cartilage defects in people with knee osteoarthritis. Osteoarthritis Cartilage (2007) 1.47
The pathobiology of focal lesion development in aging human articular cartilage and molecular matrix changes characteristic of osteoarthritis. Arthritis Rheum (2003) 1.47
Elastic modulus of calcified cartilage is an order of magnitude less than that of subchondral bone. J Orthop Res (1994) 1.40
The immunogenicity and immunomodulatory function of osteogenic cells differentiated from mesenchymal stem cells. J Immunol (2006) 1.32
Tissue engineering of articular cartilage with biomimetic zones. Tissue Eng Part B Rev (2009) 1.30
Maturation of tissue engineered cartilage implanted in injured and osteoarthritic human knees. Tissue Eng (2006) 1.28
Immunogenicity of adult mesenchymal stem cells: lessons from the fetal allograft. Stem Cells Dev (2005) 1.28
Type X collagen expression in osteoarthritic and rheumatoid articular cartilage. Virchows Arch B Cell Pathol Incl Mol Pathol (1993) 1.23
Three-dimensional cartilage tissue engineering using adult stem cells from osteoarthritis patients. Arthritis Rheum (2007) 1.14
Identification of a stem cell niche in the zone of Ranvier within the knee joint. J Anat (2009) 1.09
Modulation of lubricin biosynthesis and tissue surface properties following cartilage mechanical injury. Arthritis Rheum (2009) 1.08
Matrix turnover in human cartilage repair tissue in autologous chondrocyte implantation. Arthritis Rheum (2001) 1.07
Distinct mesenchymal progenitor cell subsets in the adult human synovium. Rheumatology (Oxford) (2009) 1.05
Mechano-regulation of stem cell differentiation and tissue regeneration in osteochondral defects. J Biomech (2004) 1.05
Mesenchymal stem cell differentiation in an experimental cartilage defect: restriction of hypertrophy to bone-close neocartilage. Stem Cells Dev (2009) 1.05
Effects of in vitro preculture on in vivo development of human engineered cartilage in an ectopic model. Tissue Eng (2005) 1.01
Ultrastructural localisation of alkaline phosphatase activity in osteoarthritic human articular cartilage. Ann Rheum Dis (1988) 0.97
Clonal chondroprogenitors maintain telomerase activity and Sox9 expression during extended monolayer culture and retain chondrogenic potential. Osteoarthritis Cartilage (2008) 0.95
Maturation-dependent durability of spontaneous cartilage repair in rabbit knee joint. J Biomed Mater Res (1999) 0.95
Study of the collagen structure in the superficial zone and physiological state of articular cartilage using a 3D confocal imaging technique. J Orthop Surg Res (2008) 0.91
Mesenchymal progenitor cells derived from synovium and infrapatellar fat pad as a source for superficial zone cartilage tissue engineering: analysis of superficial zone protein/lubricin expression. Tissue Eng Part A (2010) 0.91
Induction of cartilage integration by a chondrocyte/collagen-scaffold implant. Biomaterials (2009) 0.90
Bioreactors in tissue engineering: scientific challenges and clinical perspectives. Adv Biochem Eng Biotechnol (2009) 0.87
On how degeneration influences load-bearing in the cartilage-bone system: a microstructural and micromechanical study. Osteoarthritis Cartilage (2007) 0.85
Immunohistochemical collagen analysis of the most superficial layer in adult articular cartilage. J Orthop Sci (2004) 0.85
Cell-based therapy in articular cartilage lesions of the knee. Arthroscopy (2009) 0.82
Cyclic loading can denature type II collagen in articular cartilage. Connect Tissue Res (2004) 0.79
Mechanisms of proteoglycan metabolism that lead to cartilage destruction in the pathogenesis of arthritis. Drugs Today (Barc) (2003) 0.79
Clinical transplantation of a tissue-engineered airway. Lancet (2008) 10.04
Chondrogenic differentiation of human embryonic stem cells: the effect of the micro-environment. Tissue Eng (2006) 1.36
Maturation of tissue engineered cartilage implanted in injured and osteoarthritic human knees. Tissue Eng (2006) 1.28
Three-dimensional cartilage tissue engineering using adult stem cells from osteoarthritis patients. Arthritis Rheum (2007) 1.14
Repair of meniscal cartilage white zone tears using a stem cell/collagen-scaffold implant. Biomaterials (2010) 1.09
Precultivation of engineered human nasal cartilage enhances the mechanical properties relevant for use in facial reconstructive surgery. Ann Surg (2006) 1.03
Biochemical markers of the mechanical quality of engineered hyaline cartilage. J Mater Sci Mater Med (2007) 1.02
Characteristics of repair tissue in second-look and third-look biopsies from patients treated with engineered cartilage: relationship to symptomatology and time after implantation. Arthritis Res Ther (2008) 1.01
Effects of in vitro preculture on in vivo development of human engineered cartilage in an ectopic model. Tissue Eng (2005) 1.01
Human fetal and adult bone marrow-derived mesenchymal stem cells use different signaling pathways for the initiation of chondrogenesis. Stem Cells Dev (2013) 0.95
A double-chamber rotating bioreactor for the development of tissue-engineered hollow organs: from concept to clinical trial. Biomaterials (2009) 0.92
Induction of cartilage integration by a chondrocyte/collagen-scaffold implant. Biomaterials (2009) 0.90
Quantitative analysis of repair tissue biopsies following chondrocyte implantation. Novartis Found Symp (2003) 0.82
Chondrocyte isolation, expansion, and culture on polymer scaffolds. Methods Mol Biol (2004) 0.78
A new methodological sequence to expand and transdifferentiate human umbilical cord blood derived CD133+ cells into a cardiomyocyte-like phenotype. Stem Cell Rev (2013) 0.76
Five novel glucose-6-phosphate dehydrogenase deficiency haplotypes correlating with disease severity. J Transl Med (2012) 0.75
Directing chondrogenesis of stem cells with specific blends of cellulose and silk. Biomacromolecules (2013) 0.75