Published in Neurobiol Dis on September 29, 2010
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Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling. Front Cell Neurosci (2015) 0.79
Vitamin E dietary supplementation improves neurological symptoms and decreases c-Abl/p73 activation in Niemann-Pick C mice. Nutrients (2014) 0.78
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Increased activity of hepatic microsomal triglyceride transfer protein and bile acid synthesis in gallstone disease. Hepatology (2007) 2.05
Effects of hepatic expression of the high-density lipoprotein receptor SR-BI on lipoprotein metabolism and female fertility. Endocrinology (2006) 1.83
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HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction. PLoS Biol (2010) 1.42
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Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy. Hum Mol Genet (2012) 1.36
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Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons. Autophagy (2013) 1.34
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Diet as a risk factor for cholesterol gallstone disease. J Am Coll Nutr (2004) 1.25
Hemizygosity at the NCF1 gene in patients with Williams-Beuren syndrome decreases their risk of hypertension. Am J Hum Genet (2006) 1.23
SynCAM 1 adhesion dynamically regulates synapse number and impacts plasticity and learning. Neuron (2010) 1.22
BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response. EMBO J (2011) 1.21
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Trolox and 17beta-estradiol protect against amyloid beta-peptide neurotoxicity by a mechanism that involves modulation of the Wnt signaling pathway. J Biol Chem (2005) 1.14
Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C disease. FASEB J (2008) 1.14
Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress. PLoS One (2010) 1.11
Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1. Proc Natl Acad Sci U S A (2014) 1.11
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Lateral assembly of the immunoglobulin protein SynCAM 1 controls its adhesive function and instructs synapse formation. EMBO J (2011) 1.06
Amyloid β-peptide oligomers stimulate RyR-mediated Ca2+ release inducing mitochondrial fragmentation in hippocampal neurons and prevent RyR-mediated dendritic spine remodeling produced by BDNF. Antioxid Redox Signal (2011) 1.04
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Arabidopsis thaliana mutants lacking ADP-glucose pyrophosphorylase accumulate starch and wild-type ADP-glucose content: further evidence for the occurrence of important sources, other than ADP-glucose pyrophosphorylase, of ADP-glucose linked to leaf starch biosynthesis. Plant Cell Physiol (2011) 0.99
The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity. Arch Toxicol (2014) 0.98
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NPC2 is expressed in human and murine liver and secreted into bile: potential implications for body cholesterol homeostasis. Hepatology (2006) 0.97
Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation. Brain (2009) 0.96
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Cholecystectomy increases hepatic triglyceride content and very-low-density lipoproteins production in mice. Liver Int (2010) 0.94
Hepatic overexpression of caveolins increases bile salt secretion in mice. Hepatology (2003) 0.94
Oxidative stress triggers the amyloidogenic pathway in human vascular smooth muscle cells. Neurobiol Aging (2007) 0.94
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Synaptic clustering of PSD-95 is regulated by c-Abl through tyrosine phosphorylation. J Neurosci (2010) 0.92
Escherichia coli glycogen genes are organized in a single glgBXCAP transcriptional unit possessing an alternative suboperonic promoter within glgC that directs glgAP expression. Biochem J (2011) 0.91
Hepatic overexpression of sterol carrier protein-2 inhibits VLDL production and reciprocally enhances biliary lipid secretion. J Lipid Res (2002) 0.91
Targeting autophagy in ALS: a complex mission. Autophagy (2011) 0.90
The unfolded protein response in Alzheimer's disease. Semin Immunopathol (2013) 0.90
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Modification of γ-secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease. EMBO Mol Med (2012) 0.90
Activation of PKR causes amyloid ß-peptide accumulation via de-repression of BACE1 expression. PLoS One (2011) 0.90
Oxidative stress: a pathogenic mechanism for Niemann-Pick type C disease. Oxid Med Cell Longev (2012) 0.90
AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington's disease. Biochem Biophys Res Commun (2012) 0.89
The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling. Biochem Biophys Res Commun (2009) 0.88
Targeting the unfolded protein response for disease intervention. Expert Opin Ther Targets (2015) 0.88
Enhancing the expression of starch synthase class IV results in increased levels of both transitory and long-term storage starch. Plant Biotechnol J (2011) 0.87
Npc1 deficiency in the C57BL/6J genetic background enhances Niemann-Pick disease type C spleen pathology. Biochem Biophys Res Commun (2011) 0.87
Abnormal calcium homeostasis and protein folding stress at the ER: A common factor in familial and infectious prion disorders. Commun Integr Biol (2011) 0.87
Rare variants in calcium homeostasis modulator 1 (CALHM1) found in early onset Alzheimer's disease patients alter calcium homeostasis. PLoS One (2013) 0.87
Molecular mechanisms of neurotoxicity of pathological prion protein. Curr Mol Med (2004) 0.86
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Altered Prion protein expression pattern in CSF as a biomarker for Creutzfeldt-Jakob disease. PLoS One (2012) 0.85
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Astrocytic αVβ3 integrin inhibits neurite outgrowth and promotes retraction of neuronal processes by clustering Thy-1. PLoS One (2012) 0.84
Functional contribution of the transcription factor ATF4 to the pathogenesis of amyotrophic lateral sclerosis. PLoS One (2013) 0.84
Overexpression of the cholesterol-binding protein MLN64 induces liver damage in the mouse. World J Gastroenterol (2007) 0.84
Corticotropin-releasing factor binding protein enters the regulated secretory pathway in neuroendocrine cells and cortical neurons. Neuropeptides (2011) 0.84
p73 participates in male germ cells apoptosis induced by etoposide. Mol Hum Reprod (2010) 0.83
Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease. Autophagy (2012) 0.83
Extracellular α-synuclein alters synaptic transmission in brain neurons by perforating the neuronal plasma membrane. J Neurochem (2015) 0.82
Cholinergic abnormalities, endosomal alterations and up-regulation of nerve growth factor signaling in Niemann-Pick type C disease. Mol Neurodegener (2012) 0.82
STARTing to understand MLN64 function in cholesterol transport. J Lipid Res (2010) 0.82
Consolidation of object recognition memory requires HRI kinase-dependent phosphorylation of eIF2α in the hippocampus. Hippocampus (2013) 0.81
Lysosomal vitamin E accumulation in Niemann-Pick type C disease. Biochim Biophys Acta (2011) 0.81
Herp depletion protects from protein aggregation by up-regulating autophagy. Biochim Biophys Acta (2013) 0.81
Inactivation of hepatic microsomal triglyceride transfer protein protects mice from diet-induced gallstones. Gastroenterology (2006) 0.81
On-chip impedimetric detection of bacteriophages in dairy samples. Biosens Bioelectron (2008) 0.81
Transient expression of progesterone receptor and cathepsin-l in human granulosa cells during the periovulatory period. Fertil Steril (2012) 0.81
A BAX/BAK and cyclophilin D-independent intrinsic apoptosis pathway. PLoS One (2012) 0.80
Molecular Mechanisms Underlying the Link between Nuclear Receptor Function and Cholesterol Gallstone Formation. J Lipids (2011) 0.80
Increased copper levels in in vitro and in vivo models of Niemann-Pick C disease. Biometals (2012) 0.80
Proteostasis impairment: at the intersection between Alzheimer's disease and diabetes. Cell Metab (2013) 0.80
GlgS, described previously as a glycogen synthesis control protein, negatively regulates motility and biofilm formation in Escherichia coli. Biochem J (2013) 0.80