Published in Matrix Biol on September 25, 2010
Dynamic stiffening of poly(ethylene glycol)-based hydrogels to direct valvular interstitial cell phenotype in a three-dimensional environment. Biomaterials (2015) 1.08
Microarray analyses to quantify advantages of 2D and 3D hydrogel culture systems in maintaining the native valvular interstitial cell phenotype. Biomaterials (2015) 0.93
Role of cell-matrix interactions on VIC phenotype and tissue deposition in 3D PEG hydrogels. J Tissue Eng Regen Med (2013) 0.93
EMT-inducing biomaterials for heart valve engineering: taking cues from developmental biology. J Cardiovasc Transl Res (2011) 0.91
Manipulation of valve composition to elucidate the role of collagen in aortic valve calcification. BMC Cardiovasc Disord (2014) 0.86
Directing valvular interstitial cell myofibroblast-like differentiation in a hybrid hydrogel platform. Adv Healthc Mater (2014) 0.84
Laser microfabricated poly(glycerol sebacate) scaffolds for heart valve tissue engineering. J Biomed Mater Res A (2012) 0.80
Comparison of Mesenchymal Stem Cell Source Differentiation Toward Human Pediatric Aortic Valve Interstitial Cells within 3D Engineered Matrices. Tissue Eng Part C Methods (2015) 0.79
Myocardial contraction and hyaluronic acid mechanotransduction in epithelial-to-mesenchymal transformation of endocardial cells. Biomaterials (2014) 0.78
Hyaluronan turnover and hypoxic brown adipocytic differentiation are co-localized with ossification in calcified human aortic valves. Pathol Res Pract (2012) 0.78
Ascorbic acid promotes extracellular matrix deposition while preserving valve interstitial cell quiescence within 3D hydrogel scaffolds. J Tissue Eng Regen Med (2015) 0.76
Calcific Aortic Valve Disease Is Associated with Layer-Specific Alterations in Collagen Architecture. PLoS One (2016) 0.75
Adhesive Peptide Sequences Regulate Valve Interstitial Cell Adhesion, Phenotype and Extracellular Matrix Deposition. Cell Mol Bioeng (2016) 0.75
Hyaluronan Hydrogels for a Biomimetic Spongiosa Layer of Tissue Engineered Heart Valve Scaffolds. Biomacromolecules (2016) 0.75
Differential cell-matrix responses in hypoxia-stimulated aortic versus mitral valves. J R Soc Interface (2016) 0.75
Wave mice: a new tool in the quest to characterize aortic valvular disease etiologies. J Thorac Dis (2015) 0.75
Application of hydrogels in heart valve tissue engineering. J Long Term Eff Med Implants (2015) 0.75
Valve Interstitial Cells: The Key to Understanding the Pathophysiology of Heart Valve Calcification. J Am Heart Assoc (2017) 0.75
Heart Valve Biomechanics and Underlying Mechanobiology. Compr Physiol (2016) 0.75
The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch Biochem Biophys (1961) 19.31
Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation (2008) 15.35
Bone formation and inflammation in cardiac valves. Circulation (2001) 6.01
An Alizarin red-based assay of mineralization by adherent cells in culture: comparison with cetylpyridinium chloride extraction. Anal Biochem (2004) 4.12
Signaling properties of hyaluronan receptors. J Biol Chem (2001) 3.95
Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves. Circulation (2001) 3.47
Extracellular matrix remodeling and organization in developing and diseased aortic valves. Circ Res (2006) 2.91
Human semilunar cardiac valve remodeling by activated cells from fetus to adult: implications for postnatal adaptation, pathology, and tissue engineering. Circulation (2006) 2.68
Identification and characterization of calcifying valve cells from human and canine aortic valves. J Heart Valve Dis (1999) 2.56
Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease. Circ Res (2004) 2.45
In situ elasticity modulation with dynamic substrates to direct cell phenotype. Biomaterials (2009) 2.41
Progression of aortic valve stenosis: TGF-beta1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis. Ann Thorac Surg (2003) 2.38
The emerging role of valve interstitial cell phenotypes in regulating heart valve pathobiology. Am J Pathol (2007) 2.18
The adhesion receptor CD44 promotes atherosclerosis by mediating inflammatory cell recruitment and vascular cell activation. J Clin Invest (2001) 2.04
Calcification by valve interstitial cells is regulated by the stiffness of the extracellular matrix. Arterioscler Thromb Vasc Biol (2009) 1.89
Hyaluronan-mediated angiogenesis in vascular disease: uncovering RHAMM and CD44 receptor signaling pathways. Matrix Biol (2006) 1.79
Improved and simple micro assay for sulfated glycosaminoglycans quantification in biological extracts and its use in skin and muscle tissue studies. Glycobiology (2003) 1.77
Porcine cardiac valvular subendothelial cells in culture: cell isolation and growth characteristics. J Mol Cell Cardiol (1987) 1.60
Crosslinked hyaluronan scaffolds as a biologically active carrier for valvular interstitial cells. Biomaterials (2005) 1.51
Glycosaminoglycan profiles of myxomatous mitral leaflets and chordae parallel the severity of mechanical alterations. J Am Coll Cardiol (2003) 1.51
Angiogenic oligosaccharides of hyaluronan induce multiple signaling pathways affecting vascular endothelial cell mitogenic and wound healing responses. J Biol Chem (2002) 1.50
The role of elastin in aortic valve mechanics. J Biomech (1998) 1.49
Interleukin-1 beta promotes matrix metalloproteinase expression and cell proliferation in calcific aortic valve stenosis. Atherosclerosis (2003) 1.49
Activation of valvular interstitial cells is mediated by transforming growth factor-beta1 interactions with matrix molecules. Matrix Biol (2005) 1.49
Detection of osteopontin in calcified human aortic valves. Arterioscler Thromb Vasc Biol (1997) 1.41
Cell biology of valvular interstitial cells. Can J Cardiol (1996) 1.33
Tissue engineering of functional trileaflet heart valves from human marrow stromal cells. Circulation (2002) 1.28
Substrate properties influence calcification in valvular interstitial cell culture. J Heart Valve Dis (2008) 1.28
Modulation of TGFbeta1-dependent myofibroblast differentiation by hyaluronan. Am J Pathol (2009) 1.24
Regulation of valvular interstitial cell calcification by components of the extracellular matrix. J Biomed Mater Res A (2009) 1.17
Increased cellular expression of matrix proteins that regulate mineralization is associated with calcification of native human and porcine xenograft bioprosthetic heart valves. J Clin Invest (1997) 1.16
Abundance and location of proteoglycans and hyaluronan within normal and myxomatous mitral valves. Cardiovasc Pathol (2008) 1.15
Fragment size- and dose-specific effects of hyaluronan on matrix synthesis by vascular smooth muscle cells. Biomaterials (2006) 1.15
Mechanisms of bioprosthetic heart valve failure: fatigue causes collagen denaturation and glycosaminoglycan loss. J Biomed Mater Res (1999) 1.15
Evaluation of the matrix-synthesis potential of crosslinked hyaluronan gels for tissue engineering of aortic heart valves. Biomaterials (2005) 1.14
Hyaluronan attenuates transforming growth factor-beta1-mediated signaling in renal proximal tubular epithelial cells. Am J Pathol (2004) 1.13
Material-based regulation of the myofibroblast phenotype. Biomaterials (2007) 1.11
Valve proteoglycan content and glycosaminoglycan fine structure are unique to microstructure, mechanical load and age: Relevance to an age-specific tissue-engineered heart valve. Acta Biomater (2008) 1.08
Role of the MAPK/ERK pathway in valvular interstitial cell calcification. Am J Physiol Heart Circ Physiol (2009) 1.08
The effect of bioactive hydrogels on the secretion of extracellular matrix molecules by valvular interstitial cells. Biomaterials (2008) 1.07
Natural antisense mRNAs to hyaluronan synthase 2 inhibit hyaluronan biosynthesis and cell proliferation. J Biol Chem (2005) 1.06
Loss of chondroitin 6-sulfate and hyaluronan from failed porcine bioprosthetic valves. J Biomed Mater Res A (2003) 1.03
Characterization of structural and signaling molecules by human valve interstitial cells and comparison to human mesenchymal stem cells. J Heart Valve Dis (2007) 0.95
Hyaluronan and its receptor CD44 in the heart of newborn and adult rats. Anat Rec A Discov Mol Cell Evol Biol (2006) 0.94
Significant changes in mitral valve leaflet matrix composition and turnover with tachycardia-induced cardiomyopathy. Circulation (2009) 0.93
Hyaluronic acid cues for functional endothelialization of vascular constructs. J Tissue Eng Regen Med (2008) 0.91
Transforming growth factor beta 1-hyaluronic acid interaction. Cell Tissue Res (1995) 0.88
Differential effects of exogenous and endogenous hyaluronan on contraction and strength of collagen gels. Acta Biomater (2008) 0.81
Hyaluronan uptake by adult human skin fibroblasts in vitro. Eur J Histochem (2003) 0.79
Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease. Circ Res (2004) 2.45
A research mentor training curriculum for clinical and translational researchers. Clin Transl Sci (2012) 2.21
Photocrosslinkable polyvinyl alcohol hydrogels that can be modified with cell adhesion peptides for use in tissue engineering. Biomaterials (2002) 1.50
Immobilized gradients of epidermal growth factor promote accelerated and directed keratinocyte migration. Wound Repair Regen (2007) 1.17
Regulation of valvular interstitial cell calcification by components of the extracellular matrix. J Biomed Mater Res A (2009) 1.17
Role of the MAPK/ERK pathway in valvular interstitial cell calcification. Am J Physiol Heart Circ Physiol (2009) 1.08
Surface grafted antibodies: controlled architecture permits enhanced antigen detection. Langmuir (2005) 1.02
Efficacy of simvastatin treatment of valvular interstitial cells varies with the extracellular environment. Arterioscler Thromb Vasc Biol (2008) 1.01
Can valvular interstitial cells become true osteoblasts? A side-by-side comparison. J Heart Valve Dis (2011) 0.98
Regulation of valvular interstitial cell calcification by adhesive peptide sequences. J Biomed Mater Res A (2010) 0.98
Role of the Rho pathway in regulating valvular interstitial cell phenotype and nodule formation. Am J Physiol Heart Circ Physiol (2010) 0.96
Nylon-3 copolymers that generate cell-adhesive surfaces identified by library screening. J Am Chem Soc (2009) 0.92
In vitro adipogenic differentiation of preadipocytes varies with differentiation stimulus, culture dimensionality, and scaffold composition. Tissue Eng Part A (2009) 0.92
Nylon-3 polymers with selective antifungal activity. J Am Chem Soc (2013) 0.91
Measurement of single-cell adhesion strength using a microfluidic assay. Biomed Microdevices (2010) 0.91
Tuning the biological activity profile of antibacterial polymers via subunit substitution pattern. J Am Chem Soc (2014) 0.90
Structure-activity relationships among antifungal nylon-3 polymers: identification of materials active against drug-resistant strains of Candida albicans. J Am Chem Soc (2014) 0.89
Detection of antigens in biologically complex fluids with photografted whole antibodies. Anal Chem (2006) 0.88
Manipulation of valve composition to elucidate the role of collagen in aortic valve calcification. BMC Cardiovasc Disord (2014) 0.86
Polymer chain length effects on fibroblast attachment on nylon-3-modified surfaces. Biomacromolecules (2012) 0.86
Ternary nylon-3 copolymers as host-defense peptide mimics: beyond hydrophobic and cationic subunits. J Am Chem Soc (2014) 0.85
Serum deprivation improves seeding and repopulation of acellular matrices with valvular interstitial cells. J Biomed Mater Res A (2005) 0.85
Regulation of polyurethane hemocompatibility and endothelialization by tethered hyaluronic acid oligosaccharides. Biomaterials (2009) 0.84
Co-immobilization of gradient-patterned growth factors for directed cell migration. Ann Biomed Eng (2008) 0.83
Regulation of keratinocyte signaling and function via changes in epidermal growth factor presentation. Acta Biomater (2010) 0.82
Sex-related differences in gene expression by porcine aortic valvular interstitial cells. PLoS One (2012) 0.82
Experimental and computational analysis of cellular interactions with nylon-3-bearing substrates. J Biomed Mater Res A (2012) 0.82
Nylon-3 polymers active against drug-resistant Candida albicans biofilms. J Am Chem Soc (2015) 0.81
Influence of substrate composition on human embryonic stem cell differentiation and extracellular matrix production in embryoid bodies. Biotechnol Prog (2014) 0.80
The haemocompatibility of polyurethane-hyaluronic acid copolymers. Biomaterials (2007) 0.80
Polyurethane/dermatan sulfate copolymers as hemocompatible, non-biofouling materials. Macromol Biosci (2010) 0.79
Nylon-3 polymers that enable selective culture of endothelial cells. J Am Chem Soc (2013) 0.79
Controlled polymerization chemistry to graft architectures that influence cell-material interactions. Acta Biomater (2007) 0.79
A time course investigation of the statin paradox among valvular interstitial cell phenotypes. Am J Physiol Heart Circ Physiol (2012) 0.77
Regulation of cell signaling and function via changes in growth factor presentation. Conf Proc IEEE Eng Med Biol Soc (2009) 0.77
Differential support of cell adhesion and growth by copolymers of polyurethane with hyaluronic acid. J Biomed Mater Res A (2013) 0.76
Screening nylon-3 polymers, a new class of cationic amphiphiles, for siRNA delivery. Mol Pharm (2014) 0.75
Effect of hyaluronic acid incorporation method on the stability and biological properties of polyurethane-hyaluronic acid biomaterials. J Mater Sci Mater Med (2013) 0.75