PubRank

Debra J Taxman

Author PubWeight™ 35.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity 2009 6.37
2 Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC. Cell Host Microbe 2007 3.52
3 NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways. J Immunol 2009 2.39
4 Discovery of a viral NLR homolog that inhibits the inflammasome. Science 2011 2.36
5 CIITA-regulated plexin-A1 affects T-cell-dendritic cell interactions. Nat Immunol 2003 2.13
6 Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes. J Immunol 2007 1.97
7 Cutting edge: NLRC5-dependent activation of the inflammasome. J Immunol 2010 1.66
8 Chromosomal clustering of genes controlled by the aire transcription factor. Proc Natl Acad Sci U S A 2005 1.49
9 The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity 2012 1.44
10 Cutting edge: Monarch-1: a pyrin/nucleotide-binding domain/leucine-rich repeat protein that controls classical and nonclassical MHC class I genes. J Immunol 2003 1.33
11 Deletion of ripA alleviates suppression of the inflammasome and MAPK by Francisella tularensis. J Immunol 2010 1.27
12 Critical role of apoptotic speck protein containing a caspase recruitment domain (ASC) and NLRP3 in causing necrosis and ASC speck formation induced by Porphyromonas gingivalis in human cells. J Immunol 2009 1.26
13 Cross-regulation between the IL-1β/IL-18 processing inflammasome and other inflammatory cytokines. Curr Opin Immunol 2011 1.17
14 Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome. J Leukoc Biol 2012 1.11
15 Short hairpin RNA (shRNA): design, delivery, and assessment of gene knockdown. Methods Mol Biol 2010 1.07
16 Cutting edge: rho activation and actin polarization are dependent on plexin-A1 in dendritic cells. J Immunol 2006 0.92
17 Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition. Clin Cancer Res 2002 0.92
18 Selective targeting of leukemic cell growth in vivo and in vitro using a gene silencing approach to diminish S-adenosylmethionine synthesis. J Biol Chem 2008 0.87
19 Protein phosphatase 2A catalytic subunit α plays a MyD88-dependent, central role in the gene-specific regulation of endotoxin tolerance. Cell Rep 2013 0.86
20 Global functional analysis of nucleophosmin in Taxol response, cancer, chromatin regulation, and ribosomal DNA transcription. Exp Cell Res 2006 0.81
21 Downregulation of immune signaling genes in patients with large surface burn injury. J Burn Care Res 2007 0.81