Microtubule +TIPs at a glance.

EBs recognize a nucleotide-dependent structural cap at growing microtubule ends. Cell (2012) 2.24

Light-induced cell damage in live-cell super-resolution microscopy. Sci Rep (2015) 1.72

Estimating the microtubule GTP cap size in vivo. Curr Biol (2012) 1.71

EB1 accelerates two conformational transitions important for microtubule maturation and dynamics. Curr Biol (2014) 1.55

Aurora B suppresses microtubule dynamics and limits central spindle size by locally activating KIF4A. J Cell Biol (2013) 1.13

Writing and Reading the Tubulin Code. J Biol Chem (2015) 1.10

End-binding proteins EB3 and EB1 link microtubules to ankyrin G in the axon initial segment. Proc Natl Acad Sci U S A (2011) 1.08

Regulation of localization and activity of the microtubule depolymerase MCAK. Bioarchitecture (2011) 1.01

The axonal cytoskeleton: from organization to function. Front Mol Neurosci (2015) 0.96

Sequence determinants of a microtubule tip localization signal (MtLS). J Biol Chem (2012) 0.95

Recruitment of EB1, a master regulator of microtubule dynamics, to the surface of the Theileria annulata schizont. PLoS Pathog (2013) 0.95

Multiparametric analysis of CLASP-interacting protein functions during interphase microtubule dynamics. Mol Cell Biol (2013) 0.93

Cytokinesis defines a spatial landmark for hepatocyte polarization and apical lumen formation. J Cell Sci (2014) 0.91

EB1 regulates tubulin and actin cytoskeletal networks at the sertoli cell blood-testis barrier in male rats: an in vitro study. Endocrinology (2014) 0.90

The Gas2 family protein Pigs is a microtubule +TIP that affects cytoskeleton organisation. J Cell Sci (2015) 0.89

Cytoskeletal social networking in the growth cone: How +TIPs mediate microtubule-actin cross-linking to drive axon outgrowth and guidance. Cytoskeleton (Hoboken) (2016) 0.88

TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation. Biol Open (2015) 0.88

A proteomic approach reveals integrin activation state-dependent control of microtubule cortical targeting. Nat Commun (2015) 0.87

A proteomic study of mitotic phase-specific interactors of EB1 reveals a role for SXIP-mediated protein interactions in anaphase onset. Biol Open (2015) 0.87

A phenotypic screen identifies microtubule plus end assembly regulators that can function in mitotic spindle orientation. Cell Cycle (2015) 0.86

Regulation of Microtubule Growth and Catastrophe: Unifying Theory and Experiment. Trends Cell Biol (2015) 0.85

Single-particle imaging reveals intraflagellar transport-independent transport and accumulation of EB1 in Chlamydomonas flagella. Mol Biol Cell (2015) 0.82

Meiotic Clade AAA ATPases: Protein Polymer Disassembly Machines. J Mol Biol (2015) 0.82

Drosophila tubulin-binding cofactor B is required for microtubule network formation and for cell polarity. Mol Biol Cell (2012) 0.82

Drosophila CLIP-190 and mammalian CLIP-170 display reduced microtubule plus end association in the nervous system. Mol Biol Cell (2015) 0.82

Neurodegeneration and microtubule dynamics: death by a thousand cuts. Front Cell Neurosci (2015) 0.82

Prostate-derived sterile 20-like kinases (PSKs/TAOKs) are activated in mitosis and contribute to mitotic cell rounding and spindle positioning. J Biol Chem (2011) 0.82

The microtubule plus-end tracking proteins SPR1 and EB1b interact to maintain polar cell elongation and directional organ growth in Arabidopsis. Plant Cell (2014) 0.82

Mechanisms of Chromosome Congression during Mitosis. Biology (Basel) (2017) 0.82

Near-atomic cryo-EM structure of PRC1 bound to the microtubule. Proc Natl Acad Sci U S A (2016) 0.81

End-binding 1 protein overexpression correlates with glioblastoma progression and sensitizes to Vinca-alkaloids in vitro and in vivo. Oncotarget (2014) 0.81

FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor ARHGEF2 to decrease actomyosin contractility. Sci Signal (2012) 0.80

Mitotic redistribution of the mitochondrial network by Miro and Cenp-F. Nat Commun (2015) 0.80

Preparation of segmented microtubules to study motions driven by the disassembling microtubule ends. J Vis Exp (2014) 0.79

A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly. Sci Rep (2015) 0.79

Swinging a sword: how microtubules search for their targets. Syst Synth Biol (2014) 0.79

A STRIPAK component Strip regulates neuronal morphogenesis by affecting microtubule stability. Sci Rep (2015) 0.78

Septin cooperation with tubulin polyglutamylation contributes to cancer cell adaptation to taxanes. Oncotarget (2015) 0.78

A defect in the CLIP1 gene (CLIP-170) can cause autosomal recessive intellectual disability. Eur J Hum Genet (2014) 0.78

Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends. Dev Cell (2016) 0.78

Anti-migratory effect of vinflunine in endothelial and glioblastoma cells is associated with changes in EB1 C-terminal detyrosinated/tyrosinated status. PLoS One (2013) 0.78

Marshalin, a microtubule minus-end binding protein, regulates cytoskeletal structure in the organ of Corti. Biol Open (2013) 0.78

Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin. Nat Commun (2016) 0.78

Regulation of blood-testis barrier by actin binding proteins and protein kinases. Reproduction (2015) 0.77

C-terminal region of MAP7 domain containing protein 3 (MAP7D3) promotes microtubule polymerization by binding at the C-terminal tail of tubulin. PLoS One (2014) 0.77

Microtubules CLASP to Adherens Junctions in epidermal progenitor cells. Bioarchitecture (2014) 0.77

Characterization of Adenomatous Polyposis Coli Protein Dynamics and Localization at the Centrosome. Cancers (Basel) (2016) 0.77

MTB-3, a microtubule plus-end tracking protein (+TIP) of Neurospora crassa. PLoS One (2013) 0.76

A conceptual view at microtubule plus end dynamics in neuronal axons. Brain Res Bull (2016) 0.76

EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice. Nat Commun (2016) 0.76

Microtubule-Associated Protein EB3 Regulates IP3 Receptor Clustering and Ca(2+) Signaling in Endothelial Cells. Cell Rep (2015) 0.76

The role of +TIPs in directional tip expansion. Mol Microbiol (2014) 0.76

Deficiency of RITA results in multiple mitotic defects by affecting microtubule dynamics. Oncogene (2016) 0.75

The HIV-1 protein Vpr impairs phagosome maturation by controlling microtubule-dependent trafficking. J Cell Biol (2015) 0.75

Is toxicant-induced Sertoli cell injury in vitro a useful model to study molecular mechanisms in spermatogenesis? Semin Cell Dev Biol (2016) 0.75

Transport of germ cells across the seminiferous epithelium during spermatogenesis-the involvement of both actin- and microtubule-based cytoskeletons. Tissue Barriers (2016) 0.75

Interaction of microtubules with the actin cytoskeleton via cross-talk of EB1-containing +TIPs and γ-actin in epithelial cells. Oncotarget (2016) 0.75

Microfabricated Systems and Assays for Studying the Cytoskeletal Organization, Micromechanics, and Motility Patterns of Cancerous Cells. Adv Mater Interfaces (2014) 0.75

Tau antagonizes end-binding protein tracking at microtubule ends through a phosphorylation-dependent mechanism. Mol Biol Cell (2016) 0.75

Microtubule stabilising peptides rescue tau phenotypes in-vivo. Sci Rep (2016) 0.75

The Microtubule-Stabilizing Protein CLASP1 Associates with the Theileria annulata Schizont Surface via Its Kinetochore-Binding Domain. mSphere (2017) 0.75

Tracking the ends: a dynamic protein network controls the fate of microtubule tips. Nat Rev Mol Cell Biol (2008) 7.15

An EB1-binding motif acts as a microtubule tip localization signal. Cell (2009) 4.08

Structural basis for the regulation of tubulin by vinblastine. Nature (2005) 3.10

ELM--the database of eukaryotic linear motifs. Nucleic Acids Res (2011) 2.84

Mammalian end binding proteins control persistent microtubule growth. J Cell Biol (2009) 2.82

STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER. Curr Biol (2008) 2.79

Structural basis of the 9-fold symmetry of centrioles. Cell (2011) 2.73

Key interaction modes of dynamic +TIP networks. Mol Cell (2006) 2.18

Structure-function relationship of CAP-Gly domains. Nat Struct Mol Biol (2007) 2.02

Molecular mechanism of action of microtubule-stabilizing anticancer agents. Science (2013) 1.97

COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activity. Proc Natl Acad Sci U S A (2004) 1.85

Structural insights into the EB1-APC interaction. EMBO J (2004) 1.82

The Caenorhabditis elegans septin complex is nonpolar. EMBO J (2007) 1.69

In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends. Curr Biol (2010) 1.63

Exploring amyloid formation by a de novo design. Proc Natl Acad Sci U S A (2004) 1.55

Suppression of microtubule dynamic instability by the +TIP protein EB1 and its modulation by the CAP-Gly domain of p150glued. Biochemistry (2007) 1.48

Structure of a VEGF-VEGF receptor complex determined by electron microscopy. Nat Struct Mol Biol (2007) 1.48

Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates. J Neurosci (2007) 1.47

A conserved trimerization motif controls the topology of short coiled coils. Proc Natl Acad Sci U S A (2005) 1.43

A Proteome-wide screen for mammalian SxIP motif-containing microtubule plus-end tracking proteins. Curr Biol (2012) 1.38

Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2007) 1.32

13C, 15N resonance assignment of parts of the HET-s prion protein in its amyloid form. J Biomol NMR (2006) 1.30

SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. J Cell Biol (2011) 1.29

Association of the leukocyte plasma membrane with the actin cytoskeleton through coiled coil-mediated trimeric coronin 1 molecules. Mol Biol Cell (2005) 1.27

Oligomerization and multimerization are critical for angiopoietin-1 to bind and phosphorylate Tie2. J Biol Chem (2005) 1.26

Structural basis of tubulin tyrosination by tubulin tyrosine ligase. J Cell Biol (2013) 1.21

Insights into EB1 structure and the role of its C-terminal domain for discriminating microtubule tips from the lattice. Mol Biol Cell (2011) 1.19

Automated unrestricted multigene recombineering for multiprotein complex production. Nat Methods (2009) 1.19

Regulation of microtubule dynamic instability in vitro by differentially phosphorylated stathmin. J Biol Chem (2009) 1.18

Native architecture of the centriole proximal region reveals features underlying its 9-fold radial symmetry. Curr Biol (2013) 1.10

Configurational entropy elucidates the role of salt-bridge networks in protein thermostability. Protein Sci (2007) 1.06

Molecular insights into mammalian end-binding protein heterodimerization. J Biol Chem (2009) 1.05

Molecular basis of coiled-coil oligomerization-state specificity. Proc Natl Acad Sci U S A (2010) 1.04

End-binding proteins sensitize microtubules to the action of microtubule-targeting agents. Proc Natl Acad Sci U S A (2013) 1.04

Automated seamless DNA co-transformation cloning with direct expression vectors applying positive or negative insert selection. BMC Biotechnol (2010) 1.01

Solid-state NMR spectroscopy reveals that E. coli inclusion bodies of HET-s(218-289) are amyloids. Angew Chem Int Ed Engl (2009) 1.00

Structural basis of microtubule stabilization by laulimalide and peloruside A. Angew Chem Int Ed Engl (2014) 0.99

Polymorphism in an amyloid-like fibril-forming model peptide. Angew Chem Int Ed Engl (2008) 0.95

Structure of the extracellular domain of Tie receptor tyrosine kinases and localization of the angiopoietin-binding epitope. J Biol Chem (2006) 0.95

Sequence determinants of a microtubule tip localization signal (MtLS). J Biol Chem (2012) 0.95

Control of intrinsically disordered stathmin by multisite phosphorylation. J Biol Chem (2006) 0.94

Thermodynamics of the Op18/stathmin-tubulin interaction. J Biol Chem (2003) 0.93

Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry. Proc Natl Acad Sci U S A (2013) 0.92

End binding proteins are obligatory dimers. PLoS One (2013) 0.92

Insights into peroxisome function from the structure of PEX3 in complex with a soluble fragment of PEX19. J Biol Chem (2010) 0.92

De novo design of a two-stranded coiled-coil switch peptide. J Struct Biol (2006) 0.90

Interaction of mammalian end binding proteins with CAP-Gly domains of CLIP-170 and p150(glued). J Struct Biol (2011) 0.89

Laminin chain assembly is regulated by specific coiled-coil interactions. J Struct Biol (2010) 0.88

Localizing chemical groups while imaging single native proteins by high-resolution atomic force microscopy. Nano Lett (2014) 0.86

Drosophila stathmins bind tubulin heterodimers with high and variable stoichiometries. J Biol Chem (2010) 0.85

Microtubule end binding: EBs sense the guanine nucleotide state. Curr Biol (2011) 0.85

Methods of NMR structure refinement: molecular dynamics simulations improve the agreement with measured NMR data of a C-terminal peptide of GCN4-p1. J Biomol NMR (2010) 0.83

Production of in vitro amplified DNA pseudolibraries and high-throughput cDNA target amplification. BMC Biotechnol (2007) 0.82

Molecular-dynamics simulations of C- and N-terminal peptide derivatives of GCN4-p1 in aqueous solution. Chem Biodivers (2005) 0.82

High-level expression and purification of a designed angiopoietin-1 chimeric protein, COMP-Ang1, produced in Chinese hamster ovary cells. Protein J (2008) 0.80

Cooperative stabilization of microtubule dynamics by EB1 and CLIP-170 involves displacement of stably bound P(i) at microtubule ends. Biochemistry (2012) 0.79

Influence of 63Ser phosphorylation and dephosphorylation on the structure of the stathmin helical nucleation sequence: a molecular dynamics study. Biochemistry (2012) 0.78

Tyrosine-dependent capture of CAP-Gly domain-containing proteins in complex mixture by EB1 C-terminal peptidic probes. J Proteomics (2012) 0.78

Exploring the trigger sequence of the GCN4 coiled-coil: biased molecular dynamics resolves apparent inconsistencies in NMR measurements. Protein Sci (2010) 0.77

Exploring the conserved water site and hydration of a coiled-coil trimerisation motif: a MD simulation study. Chembiochem (2008) 0.76

Corrigendum: SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture. Nat Cell Biol (2016) 0.75

Structural basis for the oligomerization-state switch from a dimer to a trimer of an engineered cortexillin-1 coiled-coil variant. PLoS One (2013) 0.75

Quinazolinone-based Anticancer Agents: Synthesis, Anti-proliferative SAR, Anti-tubulin Activity and Tubulin Co-crystal Structure. J Med Chem (2017) 0.75

Erratum: Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex. Nat Cell Biol (2017) 0.75