Phototoxicity of Hoechst 33342 in time-lapse fluorescence microscopy.

PubWeight™: 0.98‹?› | Rank: Top 15%

🔗 View Article (PMID 20931137)

Published in Photochem Photobiol Sci on October 08, 2010

Authors

Martin Purschke1, Noemi Rubio, Kathryn D Held, Robert W Redmond

Author Affiliations

1: Department of Radiation Oncology, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA.

Articles citing this

Standard fluorescent imaging of live cells is highly genotoxic. Cytometry A (2013) 0.90

ABCG2-dependent dye exclusion activity and clonal potential in epithelial cells continuously growing for 1 month from limbal explants. Invest Ophthalmol Vis Sci (2011) 0.90

SiR-Hoechst is a far-red DNA stain for live-cell nanoscopy. Nat Commun (2015) 0.90

High-throughput analysis of NF-κB dynamics in single cells reveals basal nuclear localization of NF-κB and spontaneous activation of oscillations. PLoS One (2014) 0.87

Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity. Arch Toxicol (2015) 0.82

The tumor suppressive role of NUMB isoform 1 in esophageal squamous cell carcinoma. Oncotarget (2014) 0.82

A versatile, bar-coded nuclear marker/reporter for live cell fluorescent and multiplexed high content imaging. PLoS One (2013) 0.79

Cytotoxic Induction and Photoacoustic Imaging of Breast Cancer Cells Using Astaxanthin-Reduced Gold Nanoparticles. Nanomaterials (Basel) (2016) 0.76

High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities. Arch Toxicol (2016) 0.75

Oxidative Burst-Dependent NETosis Is Implicated in the Resolution of Necrosis-Associated Sterile Inflammation. Front Immunol (2016) 0.75

Human Corneal Fibroblast Pattern Evolution and Matrix Synthesis on Mechanically Biased Substrates. Tissue Eng Part A (2016) 0.75

Use of Fluorescence Lifetime Imaging Microscopy (FLIM) as a Timer of Cell Cycle S Phase. PLoS One (2016) 0.75

Articles by these authors

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death. EMBO J (2012) 2.45

Prevention of capsular contracture with photochemical tissue passivation. Plast Reconstr Surg (2014) 1.99

New insights on cell death from radiation exposure. Lancet Oncol (2005) 1.72

Medium-mediated intercellular communication is involved in bystander responses of X-ray-irradiated normal human fibroblasts. Oncogene (2005) 1.60

Photochemical tissue bonding: a promising technique for peripheral nerve repair. J Surg Res (2007) 1.46

Real-time in vivo assessment of the nerve microenvironment with coherent anti-Stokes Raman scattering microscopy. Plast Reconstr Surg (2009) 1.17

Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR. Cancer Res (2013) 1.16

Phototoxicity is not associated with photochemical tissue bonding of skin. Lasers Surg Med (2010) 1.01

Photochemically cross-linked collagen gels as three-dimensional scaffolds for tissue engineering. Tissue Eng (2007) 1.00

Improving electrophysiologic and histologic outcomes by photochemically sealing amnion to the peripheral nerve repair site. Surgery (2009) 0.96

Bystander effects induced by diffusing mediators after photodynamic stress. Radiat Res (2009) 0.96

Collagen cross-linking using rose bengal and green light to increase corneal stiffness. Invest Ophthalmol Vis Sci (2013) 0.96

The time dependence of bystander responses induced by iron-ion radiation in normal human skin fibroblasts. Radiat Res (2007) 0.96

Immunologically augmented cancer treatment using modern radiotherapy. Trends Mol Med (2013) 0.95

Deficiencies of double-strand break repair factors and effects on mutagenesis in directly gamma-irradiated and medium-mediated bystander human lymphoblastoid cells. Radiat Res (2008) 0.95

NF-kappaB inhibition improves the sensitivity of human glioblastoma cells to 5-aminolevulinic acid-based photodynamic therapy. Biochem Pharmacol (2010) 0.94

Microvascular anastomosis using a photochemical tissue bonding technique. Lasers Surg Med (2007) 0.94

Ionizing radiation-induced bystander mutagenesis and adaptation: quantitative and temporal aspects. Mutat Res (2009) 0.93

Photochemical sealing improves outcome following peripheral neurorrhaphy. J Surg Res (2008) 0.93

Enhancement of porcine skin graft adherence using a light-activated process. J Surg Res (2002) 0.91

Evaluation of photochemical tissue bonding for closure of skin incisions and excisions. Lasers Surg Med (2005) 0.90

Biomarkers and mechanisms of FANCD2 function. J Biomed Biotechnol (2008) 0.89

Pro-apoptotic signaling induced by photo-oxidative ER stress is amplified by Noxa, not Bim. Biochem Biophys Res Commun (2013) 0.89

Estrogen enhanced cell-cell signalling in breast cancer cells exposed to targeted irradiation. BMC Cancer (2008) 0.87

Spatial and temporal dynamics of in vitro photodynamic cell killing: extracellular hydrogen peroxide mediates neighbouring cell death. Photochem Photobiol Sci (2009) 0.87

Photochemical repair of Achilles tendon rupture in a rat model. J Surg Res (2005) 0.87

Secondary reactive oxygen species extend the range of photosensitization effects in cells: DNA damage produced via initial membrane photosensitization. Photochem Photobiol (2003) 0.85

Photochemical repair of vocal fold microflap defects. Laryngoscope (2011) 0.85

Light-initiated bonding of amniotic membrane to cornea. Invest Ophthalmol Vis Sci (2011) 0.84

Real-time imaging of novel spatial and temporal responses to photodynamic stress. Free Radic Biol Med (2009) 0.84

Engineering cartilage in a photochemically crosslinked collagen gel. J Knee Surg (2009) 0.84

FANCD2-deficient human fibroblasts are hypersensitive to ionising radiation at oxygen concentrations of 0% and 3% but not under normoxic conditions. Int J Radiat Biol (2009) 0.84

Introduction to clinical radiation biology. Hematol Oncol Clin North Am (2006) 0.83

Preparation and integration of human amnion nerve conduits using a light-activated technique. Plast Reconstr Surg (2009) 0.82

Targeted and non-targeted effects from combinations of low doses of energetic protons and iron ions in human fibroblasts. Int J Radiat Biol (2010) 0.82

Fourier transform emission lifetime spectrometer. Opt Lett (2007) 0.82

A p38(MAPK)/HIF-1 pathway initiated by UVB irradiation is required to induce Noxa and apoptosis of human keratinocytes. J Invest Dermatol (2010) 0.82

cPLA2-interacting protein, PLIP, causes apoptosis and decreases G1 phase in mesangial cells. Am J Physiol Renal Physiol (2005) 0.81

Validation of an incremental motor unit number estimation technique in rabbits. Muscle Nerve (2010) 0.81

Improving Outcomes in Immediate and Delayed Nerve Grafting of Peripheral Nerve Gaps Using Light-Activated Sealing of Neurorrhaphy Sites with Human Amnion Wraps. Plast Reconstr Surg (2016) 0.80

Differential bystander signaling between radioresistant chondrosarcoma cells and fibroblasts after x-ray, proton, iron ion and carbon ion exposures. Int J Radiat Oncol Biol Phys (2012) 0.80

Do the dietary supplements epigallocatechin gallate or vitamin e cause a radiomodifying response on tumors in vivo? A pilot study with murine breast carcinoma. J Soc Integr Oncol (2007) 0.80

Photochemical keratodesmos as an adjunct to sutures for bonding penetrating keratoplasty corneal incisions. J Cataract Refract Surg (2004) 0.80

American Society for Radiation Oncology (ASTRO) survey of radiation biology educators in U.S. and Canadian radiation oncology residency programs. Int J Radiat Oncol Biol Phys (2009) 0.80

Relative biological effectiveness (RBE) and out-of-field cell survival responses to passive scattering and pencil beam scanning proton beam deliveries. Phys Med Biol (2012) 0.80

Photochemical keratodesmos for bonding corneal incisions. Invest Ophthalmol Vis Sci (2004) 0.80

A photoactivated nanofiber graft material for augmented Achilles tendon repair. Lasers Surg Med (2012) 0.79

Vascular endothelial growth factor-C enhances radiosensitivity of lymphatic endothelial cells. Angiogenesis (2013) 0.78

Light-activated sutureless closure of wounds in thin skin. Lasers Surg Med (2011) 0.78

Singlet-singlet annihilation in ultraviolet matrix-assisted laser desorption/ionization studied by fluorescence spectroscopy. Rapid Commun Mass Spectrom (2002) 0.78

Why is rose bengal more phototoxic to fibroblasts in vitro than in vivo? Photochem Photobiol (2013) 0.78

Photochemical tissue bonding: a potential strategy for treating limbal stem cell deficiency. Lasers Surg Med (2011) 0.78

Light-activated sealing of skin wounds. Lasers Surg Med (2014) 0.77

Enhancing the stiffness of collagen hydrogels for delivery of encapsulated chondrocytes to articular lesions for cartilage regeneration. J Biomed Mater Res A (2014) 0.77

A light-activated method for repair of corneal surface defects. Lasers Surg Med (2011) 0.76

Two-photon irradiation of an intracellular singlet oxygen photosensitizer: achieving localized sub-cellular excitation in spatially-resolved experiments. Free Radic Res (2010) 0.76

Light-Activated Sealing of Nerve Graft Coaptation Sites Improves Outcome following Large Gap Peripheral Nerve Injury. Plast Reconstr Surg (2015) 0.75

Photochemical Tissue Passivation Attenuates AV Fistula Intimal Hyperplasia. Ann Surg (2016) 0.75

An intraluminal stent facilitates light-activated vascular anastomosis. J Trauma Acute Care Surg (2017) 0.75