Published in J Genet Genomics on September 01, 2010
Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation. Oncogene (2012) 0.93
Gastric Lgr5(+) stem cells are the cellular origin of invasive intestinal-type gastric cancer in mice. Cell Res (2016) 0.78
Cytokeratin 19 promoter directs the expression of Cre recombinase in various epithelia of transgenic mice. Oncotarget (2017) 0.75
Gastric Acid Secretion from Parietal Cells Is Mediated by a Ca(2+) Efflux Channel in the Tubulovesicle. Dev Cell (2017) 0.75
A novel 5-enolpyruvoylshikimate-3-phosphate (EPSP) synthase transgene for glyphosate resistance stimulates growth and fecundity in weedy rice (Oryza sativa) without herbicide. New Phytol (2013) 3.44
Transforming growth factor-beta-regulated miR-24 promotes skeletal muscle differentiation. Nucleic Acids Res (2008) 2.44
Complete viral RNA genome sequencing of ultra-low copy samples by sequence-independent amplification. Nucleic Acids Res (2012) 2.19
Endothelial Smad4 maintains cerebrovascular integrity by activating N-cadherin through cooperation with Notch. Dev Cell (2011) 2.17
Quantitative measurement of interocular suppression in anisometropic amblyopia: a case-control study. Ophthalmology (2013) 2.17
Ultrasonography for detection of disc displacement of temporomandibular joint: a systematic review and meta-analysis. J Oral Maxillofac Surg (2012) 2.06
Vector-virus mutualism accelerates population increase of an invasive whitefly. PLoS One (2007) 1.91
Hypersensitivity of BKCa to Ca2+ sparks underlies hyporeactivity of arterial smooth muscle in shock. Circ Res (2007) 1.67
Predictive power progesterone combined with beta human chorionic gonadotropin measurements in the outcome of threatened miscarriage. Arch Gynecol Obstet (2010) 1.64
Targeted disruption of Smad4 in cardiomyocytes results in cardiac hypertrophy and heart failure. Circ Res (2005) 1.62
Developmental control of histone mRNA and dSLBP synthesis during Drosophila embryogenesis and the role of dSLBP in histone mRNA 3' end processing in vivo. Mol Cell Biol (2002) 1.59
Production of lantipeptides in Escherichia coli. J Am Chem Soc (2010) 1.56
In vitro and in vivo anticancer activity of a novel puerarin nanosuspension against colon cancer, with high efficacy and low toxicity. Int J Pharm (2012) 1.54
Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1. Nat Cell Biol (2008) 1.51
Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease. Leuk Res (2009) 1.51
Long non-coding RNA HNF1A-AS1 regulates proliferation and migration in oesophageal adenocarcinoma cells. Gut (2013) 1.48
Smad4-mediated TGF-beta signaling in tumorigenesis. Int J Biol Sci (2010) 1.47
Detection of epithelial to mesenchymal transition in airways of a bleomycin induced pulmonary fibrosis model derived from an alpha-smooth muscle actin-Cre transgenic mouse. Respir Res (2007) 1.46
Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries. Cell Res (2013) 1.46
The hepatitis B virus X protein disrupts innate immunity by downregulating mitochondrial antiviral signaling protein. J Immunol (2010) 1.44
Squamous cell carcinoma and mammary abscess formation through squamous metaplasia in Smad4/Dpc4 conditional knockout mice. Development (2003) 1.43
Targeted disruption of Smad4 in mouse epidermis results in failure of hair follicle cycling and formation of skin tumors. Cancer Res (2005) 1.43
Selective antegrade cerebral perfusion attenuating the TLR4/NF-κB pathway during deep hypothermia circulatory arrest in a pig model. Cardiology (2014) 1.40
Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-beta-like signaling pathway. J Clin Invest (2009) 1.39
Altered contractile phenotypes of intestinal smooth muscle in mice deficient in myosin phosphatase target subunit 1. Gastroenterology (2013) 1.38
Smad4 is required for maintaining normal murine postnatal bone homeostasis. J Cell Sci (2007) 1.37
Hepatitis B virus X protein modulates oncogene Yes-associated protein by CREB to promote growth of hepatoma cells. Hepatology (2012) 1.34
miR-148a promoted cell proliferation by targeting p27 in gastric cancer cells. Int J Biol Sci (2011) 1.33
WASH inhibits autophagy through suppression of Beclin 1 ubiquitination. EMBO J (2013) 1.32
Mouse embryonic head as a site for hematopoietic stem cell development. Cell Stem Cell (2012) 1.31
Characterization of unique small RNA populations from rice grain. PLoS One (2008) 1.31
Mice lacking NKT cells but with a complete complement of CD8+ T-cells are not protected against the metabolic abnormalities of diet-induced obesity. PLoS One (2011) 1.30
Essential role of endothelial Smad4 in vascular remodeling and integrity. Mol Cell Biol (2007) 1.29
BMP4 Signaling Acts via dual-specificity phosphatase 9 to control ERK activity in mouse embryonic stem cells. Cell Stem Cell (2012) 1.29
Smad4 is required for the normal organization of the cartilage growth plate. Dev Biol (2005) 1.29
HBsAg and HBx knocked into the p21 locus causes hepatocellular carcinoma in mice. Hepatology (2004) 1.28
Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice. Cell Res (2011) 1.26
Functional screening for miRNAs targeting Smad4 identified miR-199a as a negative regulator of TGF-β signalling pathway. Nucleic Acids Res (2012) 1.24
Dendritic cells promote macrophage infiltration and comprise a substantial proportion of obesity-associated increases in CD11c+ cells in adipose tissue and liver. Diabetes (2012) 1.22
Constitutive stabilization of ß-catenin in the dental mesenchyme leads to excessive dentin and cementum formation. Biochem Biophys Res Commun (2011) 1.20
Essential role of Smad4 in maintaining cardiomyocyte proliferation during murine embryonic heart development. Dev Biol (2007) 1.20
Grb-2-associated binder 1 (Gab1) regulates postnatal ischemic and VEGF-induced angiogenesis through the protein kinase A-endothelial NOS pathway. Proc Natl Acad Sci U S A (2011) 1.17
IL-17 induces autoantibody overproduction and peripheral blood mononuclear cell overexpression of IL-6 in lupus nephritis patients. Chin Med J (Engl) (2003) 1.15
Two pairs of neurons in the central brain control Drosophila innate light preference. Science (2010) 1.14
ATHLATES: accurate typing of human leukocyte antigen through exome sequencing. Nucleic Acids Res (2013) 1.13
PTEN deficiency causes dyschondroplasia in mice by enhanced hypoxia-inducible factor 1alpha signaling and endoplasmic reticulum stress. Development (2008) 1.13
Ion sensing in the RCK1 domain of BK channels. Proc Natl Acad Sci U S A (2010) 1.13
PACT is a negative regulator of p53 and essential for cell growth and embryonic development. Proc Natl Acad Sci U S A (2007) 1.12
Identification of genes differentially expressed in cauliflower associated with resistance to Xanthomonas campestris pv. campestris. Mol Biol Rep (2010) 1.10
Effect of TGF-beta/Smad signaling pathway on lung myofibroblast differentiation. Acta Pharmacol Sin (2007) 1.10
Akt-p53-miR-365-cyclin D1/cdc25A axis contributes to gastric tumorigenesis induced by PTEN deficiency. Nat Commun (2013) 1.09
miR-21 promotes keratinocyte migration and re-epithelialization during wound healing. Int J Biol Sci (2011) 1.08
High-throughput DNA sequence data compression. Brief Bioinform (2013) 1.07
Synergistic function of Smad4 and PTEN in suppressing forestomach squamous cell carcinoma in the mouse. Cancer Res (2006) 1.06
Imaging of dynamic secretory vesicles in living pollen tubes of Picea meyeri using evanescent wave microscopy. Plant Physiol (2006) 1.05
SOCS3 promotes TLR4 response in macrophages by feedback inhibiting TGF-beta1/Smad3 signaling. Mol Immunol (2007) 1.03
MicroRNA-183 suppresses retinoblastoma cell growth, invasion and migration by targeting LRP6. FEBS J (2014) 1.02
Disruption of Smad4 in odontoblasts causes multiple keratocystic odontogenic tumors and tooth malformation in mice. Mol Cell Biol (2009) 1.02
RhesusBase: a knowledgebase for the monkey research community. Nucleic Acids Res (2012) 1.02
Potentiation of Smad-mediated transcriptional activation by the RNA-binding protein RBPMS. Nucleic Acids Res (2006) 1.01
Effect of social support on psychological-stress-induced anxiety and depressive symptoms in patients receiving peritoneal dialysis. J Psychosom Res (2008) 1.01
Genetic linkage mapping and analysis of muscle fiber-related QTLs in common carp (Cyprinus carpio L.). Mar Biotechnol (NY) (2010) 1.01
Identification of mesenchymal stem cells in aorta-gonad-mesonephros and yolk sac of human embryos. Blood (2007) 1.01
Elevated neutrophil to lymphocyte ratio predicts overall and cardiovascular mortality in maintenance peritoneal dialysis patients. Int Urol Nephrol (2012) 1.00
GM-CSF contributes to aortic aneurysms resulting from SMAD3 deficiency. J Clin Invest (2013) 0.99
Enhanced factor VIII heavy chain for gene therapy of hemophilia A. Mol Ther (2009) 0.99
Transforming growth factor β-regulated microRNA-29a promotes angiogenesis through targeting the phosphatase and tensin homolog in endothelium. J Biol Chem (2013) 0.99
Expression of growth differentiation factor 15 is positively correlated with histopathological malignant grade and in vitro cell proliferation in oral squamous cell carcinoma. Oral Oncol (2008) 0.99
Osteoblastic Wnts differentially regulate bone remodeling and the maintenance of bone marrow mesenchymal stem cells. Bone (2013) 0.98
Hepatitis B virus X protein and the estrogen receptor variant lacking exon 5 inhibit estrogen receptor signaling in hepatoma cells. Nucleic Acids Res (2006) 0.98
Accelerated re-epithelialization in Dpr2-deficient mice is associated with enhanced response to TGFbeta signaling. J Cell Sci (2008) 0.98
Performance of hybrids between weedy rice and insect-resistant transgenic rice under field experiments: implication for environmental biosafety assessment. J Integr Plant Biol (2009) 0.97
Rhesus macaques develop metabolic syndrome with reversible vascular dysfunction responsive to pioglitazone. Circulation (2011) 0.97
Chondrocyte-specific Smad4 gene conditional knockout results in hearing loss and inner ear malformation in mice. Dev Dyn (2009) 0.96
Bone morphogenetic protein-2: a potential regulator in scleral remodeling. Mol Vis (2008) 0.96
Anti-TNF-alpha therapies in systemic lupus erythematosus. J Biomed Biotechnol (2010) 0.96
Alkaline phosphatase and mortality in patients on peritoneal dialysis. Clin J Am Soc Nephrol (2014) 0.95
Genetic variants in the HLA-DRB1 gene are associated with Kashin-Beck disease in the Tibetan population. Arthritis Rheum (2011) 0.94
Angiotensin II upregulates Toll-like receptor 4 and enhances lipopolysaccharide-induced CD40 expression in rat peritoneal mesothelial cells. Inflamm Res (2009) 0.94
Functional promoter -94 ins/del ATTG polymorphism in NFKB1 gene is associated with bladder cancer risk in a Chinese population. PLoS One (2013) 0.94
Mutation analysis of the Smad3 gene in human osteoarthritis. Eur J Hum Genet (2003) 0.94
CIN85 associates with endosomal membrane and binds phosphatidic acid. Cell Res (2009) 0.94
Disruption of Smad4 in mouse epidermis leads to depletion of follicle stem cells. Mol Biol Cell (2008) 0.94
Focal adhesion kinase mediates TGF-beta1-induced renal tubular epithelial-to-mesenchymal transition in vitro. Mol Cell Biochem (2010) 0.93