Published in Genomics Proteomics Bioinformatics on September 01, 2010
Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms. Proc Natl Acad Sci U S A (1998) 39.20
Alignment of whole genomes. Nucleic Acids Res (1999) 20.02
Complete genome sequence of Neisseria meningitidis serogroup B strain MC58. Science (2000) 16.04
Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491. Nature (2000) 9.86
Pathogenicity islands and the evolution of microbes. Annu Rev Microbiol (2000) 9.51
Pathogenicity islands of virulent bacteria: structure, function and impact on microbial evolution. Mol Microbiol (1997) 9.50
Serotype antigens of Neisseria meningitidis and a proposed scheme for designation of serotypes. Rev Infect Dis (1985) 6.62
Deoxyribonucleic acid homologies among species of the genus Neisseria. J Bacteriol (1967) 3.94
Population genetics and molecular epidemiology of Neisseria meningitidis. APMIS (1998) 3.72
Comparative DNA analysis across diverse genomes. Annu Rev Genet (1998) 3.67
The changing epidemiology of invasive meningococcal disease in Canada, 1985 through 1992. Emergence of a virulent clone of Neisseria meningitidis. JAMA (1995) 3.09
Molecular characterization and expression in Escherichia coli of the gene complex encoding the polysaccharide capsule of Neisseria meningitidis group B. Proc Natl Acad Sci U S A (1989) 2.83
Functional genomics of Neisseria meningitidis pathogenesis. Nat Med (2000) 2.73
A review of vaccine research and development: meningococcal disease. Vaccine (2006) 2.64
Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18. PLoS Genet (2006) 2.47
Identification of pathogen-specific genes through microarray analysis of pathogenic and commensal Neisseria species. Microbiology (2005) 1.88
The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as 'virulence genes'. BMC Genomics (2006) 1.77
Comparative genomics of Neisseria meningitidis: core genome, islands of horizontal transfer and pathogen-specific genes. Microbiology (2006) 1.75
Comparative genomics identifies the genetic islands that distinguish Neisseria meningitidis, the agent of cerebrospinal meningitis, from other Neisseria species. Infect Immun (2002) 1.55
Finding pathogenicity islands and gene transfer events in genome data. Bioinformatics (2000) 1.36
Comparative overview of the genomic and genetic differences between the pathogenic Neisseria strains and species. Plasmid (2005) 1.10
The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as virulence genes: response. BMC Genomics (2006) 0.80
Evolution of prokaryotic genomes. Curr Top Microbiol Immunol (2002) 0.78
Estimated epidemiologic parameters and morbidity associated with pandemic H1N1 influenza. CMAJ (2009) 4.44
Topoisomerase IIIalpha and Bloom's helicase can resolve a mobile double Holliday junction substrate through convergent branch migration. Proc Natl Acad Sci U S A (2006) 1.83
Simple models for containment of a pandemic. J R Soc Interface (2006) 1.78
Global population structure and evolution of Bordetella pertussis and their relationship with vaccination. MBio (2014) 1.76
Population-wide emergence of antiviral resistance during pandemic influenza. PLoS One (2008) 1.71
Modelling strategies for controlling SARS outbreaks. Proc Biol Sci (2004) 1.71
Emergence of drug resistance: implications for antiviral control of pandemic influenza. Proc Biol Sci (2007) 1.49
Macrolide resistance and molecular types of Treponema pallidum causing primary syphilis in Shanghai, China. Clin Infect Dis (2009) 1.44
Invasive Haemophilus influenzae disease caused by non-type b strains in Northwestern Ontario, Canada, 2002-2008. Clin Infect Dis (2009) 1.36
Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity. Nat Immunol (2003) 1.34
Molecular characterization of syphilis in patients in Canada: azithromycin resistance and detection of Treponema pallidum DNA in whole-blood samples versus ulcerative swabs. J Clin Microbiol (2009) 1.33
Invasive disease caused by Haemophilus influenzae type a in Northern Ontario First Nations communities. J Med Microbiol (2010) 1.30
Retracted Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis. J Clin Invest (2002) 1.24
Estimated effects of projected climate change on the basic reproductive number of the Lyme disease vector Ixodes scapularis. Environ Health Perspect (2014) 1.24
On epidemic modeling in real time: An application to the 2009 Novel A (H1N1) influenza outbreak in Canada. BMC Res Notes (2010) 1.18
Invasive Haemophilus influenzae disease: changing epidemiology and host-parasite interactions in the 21st century. Infect Genet Evol (2009) 1.13
Invasive meningococcal disease in Quebec, Canada, due to an emerging clone of ST-269 serogroup B meningococci with serotype antigen 17 and serosubtype antigen P1.19 (B:17:P1.19). J Clin Microbiol (2006) 1.11
Highly conserved cross-reactive CD4+ T-cell HA-epitopes of seasonal and the 2009 pandemic influenza viruses. Influenza Other Respir Viruses (2010) 1.11
Genetic diversity of three lgt loci for biosynthesis of lipooligosaccharide (LOS) in Neisseria species. Microbiology (2002) 1.08
When is quarantine a useful control strategy for emerging infectious diseases? Am J Epidemiol (2006) 1.08
Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes. Arthritis Res Ther (2005) 1.07
Population genetics and antibiotic susceptibility of invasive Haemophilus influenzae in Manitoba, Canada, from 2000 to 2006. FEMS Immunol Med Microbiol (2007) 1.07
Drosophila RecQ4 has a 3'-5' DNA helicase activity that is essential for viability. J Biol Chem (2009) 1.06
Modeling spatial spread of west nile virus and impact of directional dispersal of birds. Math Biosci Eng (2006) 1.06
Extensive genomic variation within clonal complexes of Neisseria meningitidis. Genome Biol Evol (2011) 1.06
Managing public health crises: the role of models in pandemic preparedness. Influenza Other Respir Viruses (2009) 1.04
Nonencapsulated Neisseria meningitidis strain produces amylopectin from sucrose: altering the concept for differentiation between N. meningitidis and N. polysaccharea. J Clin Microbiol (2003) 1.03
A delay differential model for pandemic influenza with antiviral treatment. Bull Math Biol (2007) 1.00
Community-based measures for mitigating the 2009 H1N1 pandemic in China. PLoS One (2010) 1.00
Nationwide molecular surveillance of pandemic H1N1 influenza A virus genomes: Canada, 2009. PLoS One (2011) 1.00
A model for influenza with vaccination and antiviral treatment. J Theor Biol (2008) 0.98
Spatial dynamics of bar-headed geese migration in the context of H5N1. J R Soc Interface (2010) 0.98
Molecular typing of Treponema pallidum strains in western Canada: predominance of 14d subtypes. Sex Transm Dis (2010) 0.97
Epidemiology of serogroup B invasive meningococcal disease in Ontario, Canada, 2000 to 2010. BMC Infect Dis (2012) 0.97
Role of positive selection pressure on the evolution of H5N1 hemagglutinin. Genomics Proteomics Bioinformatics (2009) 0.97
Post-exposure prophylaxis during pandemic outbreaks. BMC Med (2009) 0.97
Transforming growth factor-beta-induced transcription of the Alzheimer beta-amyloid precursor protein gene involves interaction between the CTCF-complex and Smads. Biochem Biophys Res Commun (2002) 0.96
Canada in the face of the 2009 H1N1 pandemic. Influenza Other Respir Viruses (2010) 0.96
Campus quarantine (Fengxiao) for curbing emergent infectious diseases: lessons from mitigating A/H1N1 in Xi'an, China. J Theor Biol (2011) 0.95
Homologous recombination drives both sequence diversity and gene content variation in Neisseria meningitidis. Genome Biol Evol (2013) 0.95
The impact of prophylaxis of healthcare workers on influenza pandemic burden. J R Soc Interface (2007) 0.94
A sex-role-preference model for HIV transmission among men who have sex with men in China. BMC Public Health (2009) 0.94
Clinical prediction and diagnosis of neurosyphilis in HIV-infected patients with early Syphilis. J Clin Microbiol (2013) 0.94
Developing a temperature-driven map of the basic reproductive number of the emerging tick vector of Lyme disease Ixodes scapularis in Canada. J Theor Biol (2012) 0.94
Increase in serogroup C meningococcal disease in Canada is associated with antigenic changes in the protein antigens of the ET-15 clone of Neisseria meningitidis. J Infect Dis (2006) 0.93
Nano titanium dioxide induces the generation of ROS and potential damage in HaCaT cells under UVA irradiation. J Nanosci Nanotechnol (2010) 0.93
Superantigen-induced TCR alpha locus secondary rearrangement: role in tolerance induction. J Immunol (2002) 0.92
Nucleotide sequence diversity of the bexA gene in serotypeable Haemophilus influenzae strains recovered from invasive disease patients in Canada. J Clin Microbiol (2007) 0.91
Invasive potential of nonencapsulated disease isolates of Neisseria meningitidis. Infect Immun (2012) 0.91
Single- and multiple-dose pharmacokinetics of pirfenidone, an antifibrotic agent, in healthy Chinese volunteers. J Clin Pharmacol (2007) 0.91
Vaccination against 2009 pandemic H1N1 in a population dynamical model of Vancouver, Canada: timing is everything. BMC Public Health (2011) 0.91
A final size relation for epidemic models. Math Biosci Eng (2007) 0.90
Impaired V(D)J recombination and increased apoptosis among B cell precursors in the bone marrow of c-Abl-deficient mice. Int Immunol (2007) 0.90
Genetic analysis of Bordetella pertussis in Ontario, Canada reveals one predominant clone. Int J Infect Dis (2013) 0.90
HIV epidemic in Far-Western Nepal: effect of seasonal labor migration to India. BMC Public Health (2011) 0.89
Richards model revisited: validation by and application to infection dynamics. J Theor Biol (2012) 0.89
Projection of tuberculosis incidence with increasing immigration trends. J Theor Biol (2008) 0.89
DNA Sequence analysis of the PorB protein of nonserotypeable serogroup C ET-15 meningococci suggests a potential mutational hot spot on their serotype antigens. J Clin Microbiol (2004) 0.89
Differentiation of human Wharton's jelly cells toward nucleus pulposus-like cells after coculture with nucleus pulposus cells in vitro. Tissue Eng Part A (2011) 0.89
Threshold conditions for west nile virus outbreaks. Bull Math Biol (2008) 0.88
Evolution of the variable gene segments and recombination signal sequences of the human T-cell receptor alpha/delta locus. Immunogenetics (2004) 0.88
RecQ4: the second replicative helicase? Crit Rev Biochem Mol Biol (2010) 0.88
Chemoprotective effect of N-acetylcysteine (NAC) on cellular oxidative damages and apoptosis induced by nano titanium dioxide under UVA irradiation. Toxicol In Vitro (2010) 0.88
Linking antimicrobial prescribing to antimicrobial resistance in the ICU: before and after an antimicrobial stewardship program. Epidemics (2012) 0.87
Population profiling in China by gender and age: implication for HIV incidences. BMC Public Health (2009) 0.87
Pandemic influenza: Modelling and public health perspectives. Math Biosci Eng (2011) 0.86
Characterization of nontypeable Haemophilus influenzae collected from respiratory infections and invasive disease cases in Manitoba, Canada. FEMS Immunol Med Microbiol (2009) 0.86
Nonencapsulated or nontypeable Haemophilus influenzae are more likely than their encapsulated or serotypeable counterparts to have mutations in their fucose operon. Can J Microbiol (2011) 0.86
Spatiotemporal variation of mistletoes: a dynamic modeling approach. Bull Math Biol (2010) 0.85
Modeling and prediction of HIV in China: transmission rates structured by infection ages. Math Biosci Eng (2008) 0.85
Invasive serogroup B Neisseria meningitidis in Quebec, Canada, 2003 to 2010: persistence of the ST-269 clone since it first emerged in 2003. J Clin Microbiol (2012) 0.85
Persistent high incidence of tuberculosis among immigrants in a low-incidence country: impact of immigrants with early or late latency. Math Biosci Eng (2011) 0.85
The impact of maturation delay of mosquitoes on the transmission of West Nile virus. Math Biosci (2010) 0.85
Oscillatory viral dynamics in a delayed HIV pathogenesis model. Math Biosci (2009) 0.84
Immune response to Haemophilus influenzae type b vaccination in patients with chronic renal failure. Clin Vaccine Immunol (2012) 0.84
Antigenic and genetic characterization of serogroup C meningococci isolated from invasive meningococcal disease cases in Canada from 1999 to 2003. Can J Microbiol (2005) 0.83
Strategies for the use of oseltamivir and zanamivir during pandemic outbreaks. Can J Infect Dis Med Microbiol (2010) 0.83
Canadian beta-lactamase-negative Haemophilus influenzae isolates showing decreased susceptibility toward ampicillin have significant penicillin binding protein 3 mutations. Diagn Microbiol Infect Dis (2009) 0.83
T cell memory to evolutionarily conserved and shared hemagglutinin epitopes of H1N1 viruses: a pilot scale study. BMC Infect Dis (2013) 0.83
Identification of opcA gene in Neisseria polysaccharea: interspecies diversity of Opc protein family. Gene (2003) 0.83
Speed-accuracy trade-off in planned arm movements with delayed feedback. Neural Netw (2006) 0.83
Eradicating vector-borne diseases via age-structured culling. J Math Biol (2006) 0.83
Critical role of nosocomial transmission in the toronto sars outbreak. Math Biosci Eng (2004) 0.82
Predicting the HIV/AIDS epidemic and measuring the effect of mobility in mainland China. J Theor Biol (2012) 0.82
Molecular determination of liver fibrosis by synchrotron infrared microspectroscopy. Biochim Biophys Acta (2006) 0.82
Variability in transmissibility of the 2009 H1N1 pandemic in Canadian communities. BMC Res Notes (2011) 0.82
Invasive meningococcal disease caused by Neisseria meningitidis strains expressing both serogroup Y and W-135 antigenic specificities. J Clin Microbiol (2010) 0.82
Subcellular localization of caspase-3 activation correlates with changes in apoptotic morphology in MOLT-4 leukemia cells exposed to X-ray irradiation. Int J Oncol (2005) 0.82
Molecular characterization of four Haemophilus influenzae serotype a strains isolated from patients in Quebec, Canada. Can J Microbiol (2007) 0.82
Indigenous populations health protection: a Canadian perspective. BMC Public Health (2012) 0.82
Transcriptional activation and increase in expression of Alzheimer's beta-amyloid precursor protein gene is mediated by TGF-beta in normal human astrocytes. Biochem Biophys Res Commun (2002) 0.81
Regulatory mechanisms in the differential expression of Hemokinin-1. Neuropeptides (2008) 0.81
Molecular analysis of monoclonal antibodies to group variant capsular polysaccharide of Neisseria meningitidis: recurrent heavy chains and alternative light chain partners. Mol Immunol (2005) 0.81
Tissue-engineered allograft intervertebral disc transplantation for the treatment of degenerative disc disease: experimental study in a beagle model. Tissue Eng Part A (2012) 0.81