Fred Heffron

Author PubWeight™ 47.87‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 sciS, an icmF homolog in Salmonella enterica serovar Typhimurium, limits intracellular replication and decreases virulence. Infect Immun 2005 2.64
2 Accurate prediction of secreted substrates and identification of a conserved putative secretion signal for type III secretion systems. PLoS Pathog 2009 2.41
3 A statistical framework for protein quantitation in bottom-up MS-based proteomics. Bioinformatics 2009 2.07
4 Analysis of the Salmonella typhimurium proteome through environmental response toward infectious conditions. Mol Cell Proteomics 2006 1.82
5 Attenuated Francisella novicida transposon mutants protect mice against wild-type challenge. Infect Immun 2006 1.73
6 Coordinated regulation of virulence during systemic infection of Salmonella enterica serovar Typhimurium. PLoS Pathog 2009 1.58
7 Global systems-level analysis of Hfq and SmpB deletion mutants in Salmonella: implications for virulence and global protein translation. PLoS One 2009 1.58
8 Identification of new secreted effectors in Salmonella enterica serovar Typhimurium. Infect Immun 2005 1.58
9 Proteomic analysis of Salmonella enterica serovar typhimurium isolated from RAW 264.7 macrophages: identification of a novel protein that contributes to the replication of serovar typhimurium inside macrophages. J Biol Chem 2006 1.55
10 Analysis of cells targeted by Salmonella type III secretion in vivo. PLoS Pathog 2007 1.48
11 Top-down proteomics reveals a unique protein S-thiolation switch in Salmonella Typhimurium in response to infection-like conditions. Proc Natl Acad Sci U S A 2013 1.46
12 Discovery of novel secreted virulence factors from Salmonella enterica serovar Typhimurium by proteomic analysis of culture supernatants. Infect Immun 2010 1.44
13 Salmonella typhimurium disseminates within its host by manipulating the motility of infected cells. Proc Natl Acad Sci U S A 2006 1.42
14 Computational prediction of type III and IV secreted effectors in gram-negative bacteria. Infect Immun 2010 1.19
15 A Multi-Omic View of Host-Pathogen-Commensal Interplay in Salmonella-Mediated Intestinal Infection. PLoS One 2013 1.14
16 Bottlenecks and hubs in inferred networks are important for virulence in Salmonella typhimurium. J Comput Biol 2009 1.11
17 Gene set analyses for interpreting microarray experiments on prokaryotic organisms. BMC Bioinformatics 2008 1.11
18 Proteomics analysis of the causative agent of typhoid fever. J Proteome Res 2008 1.09
19 Salmonella modulates metabolism during growth under conditions that induce expression of virulence genes. Mol Biosyst 2013 1.02
20 Discovery of Salmonella virulence factors translocated via outer membrane vesicles to murine macrophages. Infect Immun 2011 0.98
21 A multi-pronged search for a common structural motif in the secretion signal of Salmonella enterica serovar Typhimurium type III effector proteins. Mol Biosyst 2010 0.97
22 Mutations of Francisella novicida that alter the mechanism of its phagocytosis by murine macrophages. PLoS One 2010 0.96
23 Targeted protein degradation by Salmonella under phagosome-mimicking culture conditions investigated using comparative peptidomics. Mol Cell Proteomics 2007 0.95
24 Proteomic investigation of the time course responses of RAW 264.7 macrophages to infection with Salmonella enterica. Infect Immun 2009 0.93
25 Systems analysis of multiple regulator perturbations allows discovery of virulence factors in Salmonella. BMC Syst Biol 2011 0.90
26 Technologies and approaches to elucidate and model the virulence program of salmonella. Front Microbiol 2011 0.88
27 A Comprehensive Subcellular Proteomic Survey of Salmonella Grown under Phagosome-Mimicking versus Standard Laboratory Conditions. Int J Proteomics 2012 0.88
28 Experimental annotation of post-translational features and translated coding regions in the pathogen Salmonella Typhimurium. BMC Genomics 2011 0.88
29 Comparative phosphoproteomics reveals components of host cell invasion and post-transcriptional regulation during Francisella infection. Mol Cell Proteomics 2013 0.86
30 Global analysis of Salmonella alternative sigma factor E on protein translation. J Proteome Res 2015 0.84
31 Iron transport in Francisella in the absence of a recognizable TonB protein still requires energy generated by the proton motive force. Biometals 2008 0.84
32 A method for investigating protein-protein interactions related to salmonella typhimurium pathogenesis. J Proteome Res 2009 0.83
33 RNA type III secretion signals that require Hfq. J Bacteriol 2013 0.82
34 Diverse secreted effectors are required for Salmonella persistence in a mouse infection model. PLoS One 2013 0.82
35 Quantitative PCR-based competitive index for high-throughput screening of Salmonella virulence factors. Infect Immun 2010 0.82
36 Use of high-throughput mass spectrometry to elucidate host-pathogen interactions in Salmonella. Future Microbiol 2008 0.81
37 Proteome of Salmonella Enterica Serotype Typhimurium Grown in a Low Mg/pH Medium. J Proteomics Bioinform 2009 0.81
38 Optimization of proteomic sample preparation procedures for comprehensive protein characterization of pathogenic systems. J Biomol Tech 2008 0.81
39 Performing comparative peptidomics analyses of Salmonella from different growth conditions. Methods Mol Biol 2010 0.78
40 Studying Salmonellae and Yersiniae host-pathogen interactions using integrated 'omics and modeling. Curr Top Microbiol Immunol 2013 0.76
41 New sub-family of lysozyme-like proteins shows no catalytic activity: crystallographic and biochemical study of STM3605 protein from Salmonella Typhimurium. J Struct Funct Genomics 2013 0.75