J M Midgley

Author PubWeight™ 25.37‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Stereochemical origin of some clinically significant drug safety concerns: lessons for future drug development. Adverse Drug React Toxicol Rev 1999 1.64
2 Agonist-specific coupling of a cloned Drosophila octopamine/tyramine receptor to multiple second messenger systems. EMBO J 1994 1.25
3 The determination of hydroxydopamines and other trace amines in the urine of parkinsonian patients and normal controls. Neurochem Res 1993 1.02
4 Selective inhibition of adenylyl cyclase by octopamine via a human cloned alpha 2A-adrenoceptor. Br J Pharmacol 1997 1.01
5 Activities of octopamine and synephrine stereoisomers on alpha-adrenoceptors. Br J Pharmacol 1988 0.96
6 Penetration of synthetic corticosteroids into human aqueous humour. Eye (Lond) 1990 0.96
7 Quinolones and multiresistant Plasmodium falciparum. Lancet 1988 0.88
8 Isomeric octopamines: their occurrence and functions. J Pharm Pharmacol 1987 0.88
9 The determination of biogenic amines in four strains of the fruit fly Drosophila melanogaster. J Pharm Biomed Anal 1994 0.88
10 Agonist-specific coupling of G-protein-coupled receptors to second-messenger systems. Prog Brain Res 1995 0.86
11 The expression of a cloned Drosophila octopamine/tyramine receptor in Xenopus oocytes. Brain Res 1997 0.86
12 The mammalian metabolism of R-(-)-m-synephrine. J Pharm Pharmacol 1983 0.85
13 Advantages of using development models of the carrion beetles Thanatophilus micans (Fabricius) and T. mutilatus (Castelneau) (Coleoptera: Silphidae) for estimating minimum post mortem intervals, verified with case data. Int J Legal Med 2013 0.85
14 Beta-adrenergic activities of octopamine and synephrine stereoisomers on guinea-pig atria and trachea. J Pharm Pharmacol 1987 0.83
15 m-Octopamine: normal occurrence with p-octopamine in mammalian sympathetic nerves. J Neurochem 1985 0.82
16 Identification of glycation at the N-terminus of albumin by gas chromatography-mass spectrometry. Biochem J 1989 0.82
17 Penetration of topically applied dexamethasone alcohol into human aqueous humor. Arch Ophthalmol 1988 0.81
18 Penetration of topically applied prednisolone sodium phosphate into human aqueous humour. Eye (Lond) 1989 0.81
19 Audiovisual media in medical practice. A pilot experiment. J R Coll Gen Pract 1971 0.80
20 Activities of octopamine and synephrine stereoisomers on octopaminergic receptor subtypes in locust skeletal muscle. J Pharm Pharmacol 1988 0.80
21 Effect of oral administration of vitamin C on human aqueous humor ascorbate concentration. Zhongguo Yao Li Xue Bao 1999 0.79
22 Unsaturated steroids. Part 2. A novel route to anthrasteroids: X-ray crystal structure of 1(10 leads to 6)abeo-cholesta-5,7,9-trien-3-yl p-bromobenzoate. J Chem Soc Perkin 1 1977 0.77
23 Analysis of unconjugated morphine, codeine, normorphine and morphine as glucuronides in small volumes of plasma from children. J Pharm Biomed Anal 1995 0.77
24 Measurement of urinary medium chain acyl glycines by gas chromatography--negative ion chemical ionization mass spectrometry. J Pharm Biomed Anal 1991 0.77
25 Identification and quantitation of N-acetyl metabolites of biogenic amines in the thoracic nervous system of the locust, Schistocerca gregaria, by gas chromatography-negative-ion chemical ionisation mass spectrometry. J Chromatogr 1990 0.76
26 Penetration of topically applied betamethasone sodium phosphate into human aqueous humour. Eye (Lond) 1990 0.76
27 The analysis of corticosteroid acetates by gas chromatography/negative ion chemical ionization mass spectrometry. Rapid Commun Mass Spectrom 1989 0.76
28 Intracellular localization and metabolism of the phenanthridinium trypanocide, ethidium bromide, by isolated rat hepatocytes. Xenobiotica 1999 0.75
29 Analysis of biogenic amines in plasma of hypertensive patients and a control group. Neurochem Res 1993 0.75
30 Determination of (-)-bunolol and its metabolite, dihydro-(-)-bunolol, in human aqueous humour by gas chromatography-negative ion chemical ionisation mass spectrometry. J Chromatogr 1991 0.75
31 Identification and quantification of gamma-glutamyl conjugates of biogenic amines in the nervous system of the snail, Helix aspersa, by gas chromatography-negative-ion chemical ionisation mass spectrometry. J Chromatogr 1993 0.75
32 Unsaturated steroids. Part I. Synthesis of 22,23-dihydroergosterol. J Chem Soc Perkin 1 1976 0.75
33 Analysis of biogenic amines in bovine retina by gas chromatography-negative ion chemical ionisation mass spectrometry. J Neurochem 1989 0.75
34 Identification and quantitation of phenylalanine, tyrosine and dihydroxyphenylalanine in the thoracic nervous system of the locust, Schistocerca gregaria, by gas chromatography-negative-ion chemical ionisation mass spectrometry. J Chromatogr 1990 0.75
35 Identification and quantitative determination of o- and m-hydroxymandelic acid in human urine. Biomed Mass Spectrom 1979 0.75
36 Analysis of biogenic amines in the brain of the American cockroach (Periplaneta americana) by gas chromatography-negative ion chemical ionisation mass spectrometry. J Chromatogr 1989 0.75
37 Interspecies differences in the metabolism of ethidium bromide by rat, sheep and pig hepatocytes. J Vet Pharmacol Ther 1999 0.75
38 The chemistry of fungi. Part LXXII. The trimethylsilyloxy-substituent as a leaving group. J Chem Soc Perkin 1 1976 0.75
39 Synthesis and characterisation of acyl glycines. Their measurement in single blood spots by gas chromatography-mass spectrometry to diagnose inborn errors of metabolism. J Chromatogr B Biomed Appl 1996 0.75
40 Unsaturated steroids. Part 5. Synthesis of 4alpha-methylcholest-8(9)-en-3beta-ol. J Chem Soc Perkin 1 1977 0.75
41 Comparison of o-octopamine and related phenylethanolamines as substrates for norepinephrine N-methyltransferase. Res Commun Chem Pathol Pharmacol 1981 0.75
42 Biogenic amines: their occurrence, biosynthesis and metabolism in the locust, Schistocerca gregaria, by gas chromatography-negative-ion chemical ionisation mass spectrometry. J Chromatogr 1991 0.75
43 The identification and quantitative determination of phenylephrine in adrenal gland [proceedings]. J Pharm Pharmacol 1979 0.75
44 Quantitative measurement of octopamines and synephrines in urine using capillary column gas chromatography negative ion chemical ionization mass spectrometry. Anal Chem 1984 0.75
45 Analysis of biogenic amines and their metabolites in biological tissues and fluids by gas chromatography-negative ion chemical ionization mass spectrometry (GC-NICIMS). J Pharm Biomed Anal 1990 0.75
46 Conformational studies. Part 2. Synthesis of 17beta-hydroxy-4,4-dimethyl-5alpha-androstan-3-one, and of the 19-nor analogue. J Chem Soc Perkin 1 1977 0.75
47 The determination of 5-hydroxytryptamine, related indolealkylamines and 5-hydroxyindoleacetic acid in the bovine eye by gas chromatography-negative ion chemical ionization mass spectrometry. J Pharm Biomed Anal 1993 0.75
48 The effect of inducing agents on the metabolism of ethidium bromide by isolated rat hepatocytes. Chem Biol Interact 1999 0.75
49 Unsaturated steroids. Part 7. A simple synthesis of 22,23-dihydroergosterol. J Chem Soc Perkin 1 1977 0.75
50 m-Synephrine: normal occurrence in adrenal gland. J Neurochem 1980 0.75
51 Identification and quantitative determination of 0-, m- and p- hydroxymandelic acid in human urine [proceedings]. J Pharm Pharmacol 1979 0.75
52 HPTLC and HPLC determination of isometamidium in the presence of its manufacturing and degradation impurities. J Pharm Biomed Anal 1998 0.75
53 Determination of molecular weight of hyaluronic acid in bovine vitreous humour and Healon by high performance gel permeation chromatography and its depolymerization with ascorbic acid. Pharm World Sci 1997 0.75
54 The metabolism and biosynthesis of (+/-)-o-octopamine and (+/-)-o-synephrine in the rat. J Pharm Pharmacol 1983 0.75
55 Identification and quantitative determination of m-hydroxyphenylglycol in mammalian urine. Biomed Mass Spectrom 1982 0.75
56 Unsaturated steroids. Part 3. Synthesis of steroidal 22,24(28)-dienes, erogosta-5,7,22,24(28)-tetraen-3beta-ol, and cholesta-5,7,22-trien-3beta-ol. J Chem Soc Perkin 1 1977 0.75
57 Conformational studies. Part 5. Functionalisation of methyl groups in 4,4-dimethyl steroids. J Chem Soc Perkin 1 1977 0.75
58 Increased excretion of o-hydroxymandelic acid in phenylketonuria. Biomed Mass Spectrom 1980 0.75
59 Determination of oestrone, 17alpha- and 17beta-oestradiol in bovine aqueous humor using gas chromatography-negative ion chemical ionization mass spectrometry. Arch Pharm Res 1997 0.75
60 Analysis of a residual diamine in a pharmaceutical polymer using solid phase extraction with analysis by gas chromatography mass spectrometry. J Pharm Biomed Anal 1999 0.75
61 Unsaturated steroids. Part 6. A route to cholesta-5,7-diene-1alpha,3beta-diol; Preparation of steroidal 4,6,8(14)-trienes. J Chem Soc Perkin 1 1977 0.75
62 Determination of acidic metabolites of biogenic amines in human aqueous humour by gas chromatography--negative ion chemical ionisation mass spectrometry. J Neurochem 1992 0.75
63 Increased excretion of m-Hydroxyphenylglycol and m-Hydroxymandelic acid in neuroblastoma. Biochem Med 1982 0.75
64 The metabolism of fluorometholone by bovine cornea. J Pharm Biomed Anal 1994 0.75
65 Unsaturated steroids. Part 4. Some steroidal hydroxy-4,4-dimethyl-5,7-dienes and 4,4-dimethyl-5,7,14(15)-trienes. J Chem Soc Perkin 1 1977 0.75
66 Measurement of ascorbic acid in human aqueous humour and plasma and bovine aqueous humour by high-performance liquid chromatography with electrochemical detection. J Pharm Biomed Anal 1993 0.75
67 Investigation of the chemical equivalence of the trypanocidal products, Samorin and Veridium. J Pharm Biomed Anal 1999 0.75
68 GC/MS determination of biogenic amines in insect neurons. Methods Mol Biol 1997 0.75
69 Approaches to short-acting neuromuscular blocking agents: nonsymmetrical bis-tetrahydroisoquinolinium mono- and diesters. J Med Chem 1996 0.75