Saskia Nijmeijer

Author PubWeight™ 9.55‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A structural insight into the reorientation of transmembrane domains 3 and 5 during family A G protein-coupled receptor activation. Mol Pharmacol 2010 1.14
2 Real-time visualization of heterotrimeric G protein Gq activation in living cells. BMC Biol 2011 1.00
3 Viral hijacking of human receptors through heterodimerization. Biochem Biophys Res Commun 2008 0.95
4 Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H₄ and the ion channel serotonin 5-HT₃A. Bioorg Med Chem Lett 2011 0.86
5 G protein-coupled receptors: walking hand-in-hand, talking hand-in-hand? Br J Pharmacol 2011 0.86
6 Virtual fragment screening: discovery of histamine H3 receptor ligands using ligand-based and protein-based molecular fingerprints. J Chem Inf Model 2012 0.84
7 Small and colorful stones make beautiful mosaics: fragment-based chemogenomics. Drug Discov Today 2012 0.82
8 Molecular determinants of ligand binding modes in the histamine H(4) receptor: linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies. J Med Chem 2011 0.81
9 Bispyrimidines as potent histamine H(4) receptor ligands: delineation of structure-activity relationships and detailed H(4) receptor binding mode. J Med Chem 2013 0.78
10 Significance of N-terminal proteolysis of CCL14a to activity on the chemokine receptors CCR1 and CCR5 and the human cytomegalovirus-encoded chemokine receptor US28. J Immunol 2009 0.77
11 Triazole ligands reveal distinct molecular features that induce histamine H4 receptor affinity and subtly govern H4/H3 subtype selectivity. J Med Chem 2011 0.77