Long-term survival of human neural stem cells in the ischemic rat brain upon transient immunosuppression.

PubWeight™: 1.05‹?› | Rank: Top 15%

🔗 View Article (PMC 2988794)

Published in PLoS One on November 19, 2010

Authors

Laura Rota Nodari1, Daniela Ferrari, Fabrizio Giani, Mario Bossi, Virginia Rodriguez-Menendez, Giovanni Tredici, Domenico Delia, Angelo Luigi Vescovi, Lidia De Filippis

Author Affiliations

1: Department of Biotechnologies and Biosciences, University Milano Bicocca, Milan, Italy.

Articles citing this

Transplanted neural stem/precursor cells instruct phagocytes and reduce secondary tissue damage in the injured spinal cord. Brain (2012) 1.26

Amelioration of motor/sensory dysfunction and spasticity in a rat model of acute lumbar spinal cord injury by human neural stem cell transplantation. Stem Cell Res Ther (2013) 1.25

Neural stem cell gene therapy ameliorates pathology and function in a mouse model of globoid cell leukodystrophy. Stem Cells (2011) 1.22

The immune response of stem cells in subretinal transplantation. Stem Cell Res Ther (2015) 1.05

Injected Versus Oral Cyclosporine for Human Neural Progenitor Grafting in Rats. J Stem Cell Res Ther (2012) 1.04

Hypoxia in the regulation of neural stem cells. Cell Mol Life Sci (2011) 1.04

Neural stem/progenitor cells as a promising candidate for regenerative therapy of the central nervous system. Front Cell Neurosci (2012) 0.96

Human neural stem cell transplantation in ALS: initial results from a phase I trial. J Transl Med (2015) 0.86

Concise review: self-renewal in the central nervous system: neural stem cells from embryo to adult. Stem Cells Transl Med (2012) 0.86

Endogenous neural precursors influence grafted neural stem cells and contribute to neuroprotection in the parkinsonian rat. Eur J Neurosci (2012) 0.82

Proteomic analysis of immature rat pups brain in response to hypoxia and ischemia challenge. Int J Clin Exp Pathol (2014) 0.82

Human neural stem cells alleviate Alzheimer-like pathology in a mouse model. Mol Neurodegener (2015) 0.81

ATM-deficient human neural stem cells as an in vitro model system to study neurodegeneration. DNA Repair (Amst) (2013) 0.81

Increasing doublecortin expression promotes migration of human embryonic stem cell-derived neurons. Stem Cells (2012) 0.79

Minocycline treatment and bone marrow mononuclear cell transplantation after endothelin-1 induced striatal ischemia. Inflammation (2013) 0.79

Adult stem cell as new advanced therapy for experimental neuropathic pain treatment. Biomed Res Int (2014) 0.77

Effects of atelocollagen on neural stem cell function and its migrating capacity into brain in psychiatric disease model. J Neural Transm (Vienna) (2013) 0.76

Stem cell therapy for amyotrophic lateral sclerosis. Cell Regen (Lond) (2015) 0.75

Articles cited by this

Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science (1992) 19.30

Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med (2002) 10.10

Adult neurogenesis in the mammalian central nervous system. Annu Rev Neurosci (2005) 8.96

Mechanisms underlying inflammation in neurodegeneration. Cell (2010) 7.66

Estimation of nuclear population from microtome sections. Anat Rec (1946) 7.21

Astrocytes give rise to new neurons in the adult mammalian hippocampus. J Neurosci (2001) 5.66

Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann Neurol (1982) 5.58

Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas. Proc Natl Acad Sci U S A (2000) 5.49

Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis. Nature (2003) 5.31

Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol (2005) 5.31

Anti-inflammatory mechanism of intravascular neural stem cell transplantation in haemorrhagic stroke. Brain (2007) 3.68

Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain. J Neurosci (1997) 3.61

Is there a neural stem cell in the mammalian forebrain? Trends Neurosci (1996) 3.60

Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism. Nature (2005) 3.53

Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex. Proc Natl Acad Sci U S A (2004) 3.45

Transplantation of cultured human neuronal cells for patients with stroke. Neurology (2000) 3.38

Multipotent progenitor cells in the adult dentate gyrus. J Neurobiol (1998) 3.15

A niche for adult neural stem cells. Curr Opin Genet Dev (2003) 3.05

Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor. J Neurosci (1996) 3.04

Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years. Nat Med (2008) 2.80

Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters. Nat Biotechnol (2004) 2.78

In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain. J Neurosci (1996) 2.72

Ischemia-induced neurogenesis of neocortical layer 1 progenitor cells. Nat Neurosci (2009) 2.21

Stem cells in the adult mammalian central nervous system. Curr Opin Neurobiol (1999) 2.16

Isolation and cloning of multipotential stem cells from the embryonic human CNS and establishment of transplantable human neural stem cell lines by epigenetic stimulation. Exp Neurol (1999) 2.14

bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells. Neuron (1993) 1.92

Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms. Brain (2009) 1.89

Neural transplantation for the treatment of Parkinson's disease. Lancet Neurol (2003) 1.64

Prolonged seizures increase proliferating neuroblasts in the adult rat subventricular zone-olfactory bulb pathway. J Neurosci (2002) 1.46

Human neural stem cell grafts modify microglial response and enhance axonal sprouting in neonatal hypoxic-ischemic brain injury. Stroke (2010) 1.44

Human neural stem cells can migrate, differentiate, and integrate after intravenous transplantation in adult rats with transient forebrain ischemia. Neurosci Lett (2003) 1.39

Cortical neurogenesis enhanced by chronic perinatal hypoxia. Exp Neurol (2006) 1.35

Acute injury directs the migration, proliferation, and differentiation of solid organ stem cells: evidence from the effect of hypoxia-ischemia in the CNS on clonal "reporter" neural stem cells. Exp Neurol (2006) 1.35

Mild hypoxia enhances proliferation and multipotency of human neural stem cells. PLoS One (2010) 1.35

Migration patterns and phenotypic differentiation of long-term expanded human neural progenitor cells after transplantation into the adult rat brain. Brain Res Dev Brain Res (2002) 1.32

Human neural stem cells ameliorate autoimmune encephalomyelitis in non-human primates. Ann Neurol (2009) 1.30

A novel, immortal, and multipotent human neural stem cell line generating functional neurons and oligodendrocytes. Stem Cells (2007) 1.21

Roles of the mammalian subventricular zone in cell replacement after brain injury. Prog Neurobiol (2004) 1.19

Perturbed cellular response to brain injury during aging. Ageing Res Rev (2009) 1.19

Transplantation of neural stem cells in a rat model of stroke: assessment of short-term graft survival and acute host immunological response. Brain Res (2002) 1.10

Neural cells from primary human striatal xenografts migrate extensively in the adult rat CNS. Eur J Neurosci (2002) 0.99

Experimental traumatic brain injury modulates the survival, migration, and terminal phenotype of transplanted epidermal growth factor receptor-activated neural stem cells. Neurosurgery (2005) 0.94

Reproducible loss of CA1 neurons following carotid artery occlusion combined with halothane-induced hypotension. Brain Res (2005) 0.93

Basic fibroblast growth factor supports the proliferation of epidermal growth factor-generated neuronal precursor cells of the adult mouse CNS. Neurosci Lett (1995) 0.91

Degeneration of newly formed CA1 neurons following global ischemia in the rat. Exp Neurol (2007) 0.91

Transplantation of stem cells from the adult human brain to the adult rat brain. Neurosurgery (2007) 0.90

Neuroprotection by cyclosporin A following transient brain ischemia correlates with the inhibition of the early efflux of cytochrome C to cytoplasm. Brain Res Mol Brain Res (2004) 0.88

Improving the survival of human CNS precursor-derived neurons after transplantation. J Neurosci Res (2004) 0.86

Multipotential neural precursors transplanted into the metachromatic leukodystrophy brain fail to generate oligodendrocytes but contribute to limit brain dysfunction. Dev Neurosci (2008) 0.86

Neural stem cell grafts reduce the extent of neuronal damage in a mouse model of global ischaemia. Brain Res (2005) 0.86

Robust generation of oligodendrocyte progenitors from human neural stem cells and engraftment in experimental demyelination models in mice. PLoS One (2010) 0.85

Sustained survival of xenografted human neural stem/progenitor cells in experimental brain trauma despite discontinuation of immunosuppression. Exp Neurol (2006) 0.84

Neurotransmitter synthesis in poststroke cortical neurogenesis in adult rats. Stem Cell Res (2009) 0.80

Articles by these authors

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment. Proc Natl Acad Sci U S A (2009) 4.19

Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease. Brain (2005) 3.61

Tumor-initiating cells of HER2-positive carcinoma cell lines express the highest oncoprotein levels and are sensitive to trastuzumab. Clin Cancer Res (2009) 2.14

Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice. Biol Psychiatry (2005) 1.74

G-CSF treatment of severe congenital neutropenia reverses neutropenia but does not correct the underlying functional deficiency of the neutrophil in defending against microorganisms. Blood (2007) 1.66

Neural stem cells: an overview. Circ Res (2003) 1.64

The proliferative capacity of the subventricular zone is maintained in the parkinsonian brain. Brain (2011) 1.64

Long-term survival of dopamine neurons derived from parthenogenetic primate embryonic stem cells (cyno-1) after transplantation. Stem Cells (2005) 1.56

Bortezomib-induced peripheral neurotoxicity: a neurophysiological and pathological study in the rat. Exp Neurol (2007) 1.54

The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas. Cancer Cell (2012) 1.50

Paclitaxel and Cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine. Clin Cancer Res (2003) 1.45

Immunological aspects of chronic fatigue syndrome. Autoimmun Rev (2008) 1.42

Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors. Proc Natl Acad Sci U S A (2004) 1.40

Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint. Cancer Cell (2006) 1.38

Cornelia de Lange syndrome mutations in SMC1A or SMC3 affect binding to DNA. Hum Mol Genet (2008) 1.37

Mild hypoxia enhances proliferation and multipotency of human neural stem cells. PLoS One (2010) 1.35

Junctional adhesion molecule-A-deficient polymorphonuclear cells show reduced diapedesis in peritonitis and heart ischemia-reperfusion injury. Proc Natl Acad Sci U S A (2005) 1.33

Treatment of unruptured cerebral aneurysms by embolization with guglielmi detachable coils: case-fatality, morbidity, and effectiveness in preventing bleeding--a systematic review of the literature. Neurosurgery (2004) 1.32

Emx2 regulates the proliferation of stem cells of the adult mammalian central nervous system. Development (2002) 1.24

DBC1 phosphorylation by ATM/ATR inhibits SIRT1 deacetylase in response to DNA damage. J Mol Cell Biol (2012) 1.20

Innate immunity defects in Hermansky-Pudlak type 2 syndrome. Blood (2006) 1.19

Multimodal quantal release at individual hippocampal synapses: evidence for no lateral inhibition. J Neurosci (2002) 1.18

Biological heterogeneity of putative bladder cancer stem-like cell populations from human bladder transitional cell carcinoma samples. Cancer Sci (2009) 1.17

Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt. Oncogene (2004) 1.17

Gene expression profiling of advanced ovarian cancer: characterization of a molecular signature involving fibroblast growth factor 2. Oncogene (2004) 1.16

Protective effect of erythropoietin and its carbamylated derivative in experimental Cisplatin peripheral neurotoxicity. Clin Cancer Res (2006) 1.15

Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2. Mol Cancer Ther (2007) 1.13

From cytogenomic to epigenomic profiles: monitoring the biologic behavior of in vitro cultured human bone marrow mesenchymal stem cells. Stem Cell Res Ther (2012) 1.12

Activation of ATM and Chk2 kinases in relation to the amount of DNA strand breaks. Oncogene (2004) 1.12

Impaired elimination of DNA double-strand break-containing lymphocytes in ataxia telangiectasia and Nijmegen breakage syndrome. DNA Repair (Amst) (2006) 1.08

Retinoic acid-induced neuritogenesis of human neuroblastoma SH-SY5Y cells is ERK independent and PKC dependent. J Neurosci Res (2004) 1.08

DNA damage-induced cell cycle regulation and function of novel Chk2 phosphoresidues. Mol Cell Biol (2006) 1.07

Nigrostriatal dysfunction in familial Alzheimer's disease-linked APPswe/PS1DeltaE9 transgenic mice. J Neurosci (2005) 1.07

Karyopherin-alpha2 protein interacts with Chk2 and contributes to its nuclear import. J Biol Chem (2003) 1.06

A CDKN2A mutation in familial melanoma that abrogates binding of p16INK4a to CDK4 but not CDK6. Cancer Res (2007) 1.05

Hypoxia in the regulation of neural stem cells. Cell Mol Life Sci (2011) 1.04

Monitoring the genomic stability of in vitro cultured rat bone-marrow-derived mesenchymal stem cells. Chromosome Res (2009) 1.03

Ataxia-telangiectasia-mutated dependent phosphorylation of Artemis in response to DNA damage. Cancer Sci (2005) 1.01

Damaging-agent sensitivity of Artemis-deficient cell lines. Eur J Immunol (2005) 1.00

Safety of anti-tumor necrosis factor-alpha therapy in patients with rheumatoid arthritis and chronic hepatitis C virus infection. J Rheumatol (2008) 1.00

TLR9 agonists oppositely modulate DNA repair genes in tumor versus immune cells and enhance chemotherapy effects. Cancer Res (2011) 1.00

Phenotypic variations between affected siblings with ataxia-telangiectasia: ataxia-telangiectasia in Japan. Int J Hematol (2009) 0.99

TRAP1 regulates proliferation, mitochondrial function, and has prognostic significance in NSCLC. Mol Cancer Res (2014) 0.99

GFAPdelta in radial glia and subventricular zone progenitors in the developing human cortex. Development (2010) 0.98

Intravenous neural stem cells abolish nociceptive hypersensitivity and trigger nerve regeneration in experimental neuropathy. Pain (2012) 0.98

Role of MAPKs in platinum-induced neuronal apoptosis. Neurotoxicology (2009) 0.97

The shelterin protein TRF2 inhibits Chk2 activity at telomeres in the absence of DNA damage. Curr Biol (2009) 0.97

ERK1 and ERK2 are involved in recruitment and maturation of human mesenchymal stem cells induced to adipogenic differentiation. J Mol Cell Biol (2011) 0.96

Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2. Biochem Biophys Res Commun (2008) 0.96

GM3 synthase overexpression results in reduced cell motility and in caveolin-1 upregulation in human ovarian carcinoma cells. Glycobiology (2009) 0.96

Isolation of neural stem cells from neural tissues using the neurosphere technique. Curr Protoc Stem Cell Biol (2010) 0.96

Monitoring techniques for prevention of procedure-related ischemic damage in aneurysm surgery. World Neurosurg (2011) 0.95

Brap2 functions as a cytoplasmic retention protein for p21 during monocyte differentiation. Mol Cell Biol (2004) 0.95

High values of CXCL10 serum levels in mixed cryoglobulinemia associated with hepatitis C infection. Am J Gastroenterol (2008) 0.93

SEL1L affects human pancreatic cancer cell cycle and invasiveness through modulation of PTEN and genes related to cell-matrix interactions. Neoplasia (2005) 0.93

Lingual vascular canals of the mandible: the risk of bleeding complications during implant procedures. Implant Dent (2007) 0.93

Differentiation-dependent lysine 4 acetylation enhances MEF2C binding to DNA in skeletal muscle cells. Nucleic Acids Res (2007) 0.93

A protein phosphatase feedback mechanism regulates the basal phosphorylation of Chk2 kinase in the absence of DNA damage. Biochim Biophys Acta (2010) 0.92

NFBD1/MDC1 associates with p53 and regulates its function at the crossroad between cell survival and death in response to DNA damage. J Biol Chem (2007) 0.92

ATM and the DNA damage response. Workshop on ataxia-telangiectasia and related syndromes. EMBO Rep (2006) 0.92

Detection of ATM gene mutation in human glioma cell line M059J by a rapid frameshift/stop codon assay in yeast. Radiat Res (2002) 0.91

The stem cells as a potential treatment for neurodegeneration. Methods Mol Biol (2007) 0.91

Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II: Structural and biological characterization. Bioorg Med Chem (2012) 0.90

DNA Methylation Changes during In Vitro Propagation of Human Mesenchymal Stem Cells: Implications for Their Genomic Stability? Stem Cells Int (2013) 0.90

Neurotoxicity of platinum compounds: comparison of the effects of cisplatin and oxaliplatin on the human neuroblastoma cell line SH-SY5Y. J Neurooncol (2004) 0.89

Immortalization of human neural stem cells with the c-myc mutant T58A. PLoS One (2008) 0.89

Human mesenchymal stem cells express neuronal markers after osteogenic and adipogenic differentiation. Cell Mol Biol Lett (2013) 0.89

Chronic exposure of astrocytes to interferon-α reveals molecular changes related to Aicardi-Goutieres syndrome. Brain (2013) 0.89

Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy. Bioorg Med Chem (2009) 0.89

Cisplatin-induced peripheral neuropathy: neuroprotection by erythropoietin without affecting tumour growth. Eur J Cancer (2007) 0.89

Comparative neuronal differentiation of self-renewing neural progenitor cell lines obtained from human induced pluripotent stem cells. Front Cell Neurosci (2013) 0.88

Adult mesenchymal stem cells rescue dorsal root ganglia neurons from dying. Brain Res (2006) 0.88

REGgamma proteasome activator is involved in the maintenance of chromosomal stability. Cell Cycle (2007) 0.88

Effect of the chronic combined administration of cisplatin and paclitaxel in a rat model of peripheral neurotoxicity. Eur J Cancer (2008) 0.88

Mesenchymal stem cells neuronal differentiation ability: a real perspective for nervous system repair? Curr Stem Cell Res Ther (2011) 0.88

Unique expression and localization of aquaporin-4 and aquaporin-9 in murine and human neural stem cells and in their glial progeny. Glia (2006) 0.88

Paclitaxel toxicity in post-mitotic dorsal root ganglion (DRG) cells. Anticancer Res (2006) 0.88

NGF protects dorsal root ganglion neurons from oxaliplatin by modulating JNK/Sapk and ERK1/2. Neurosci Lett (2010) 0.88

Expression and distribution of 'high affinity' glutamate transporters GLT1, GLAST, EAAC1 and of GCPII in the rat peripheral nervous system. J Anat (2008) 0.88

Role of senataxin in DNA damage and telomeric stability. DNA Repair (Amst) (2010) 0.87

A glycosphingolipid/caveolin-1 signaling complex inhibits motility of human ovarian carcinoma cells. J Biol Chem (2011) 0.87

PDGF receptor alpha inhibition induces apoptosis in glioblastoma cancer stem cells refractory to anti-Notch and anti-EGFR treatment. Mol Cancer (2014) 0.87

Novel second mitochondria-derived activator of caspases (Smac) mimetic compounds sensitize human leukemic cell lines to conventional chemotherapeutic drug-induced and death receptor-mediated apoptosis. Invest New Drugs (2010) 0.87

REGgamma/PA28gamma proteasome activator interacts with PML and Chk2 and affects PML nuclear bodies number. Cell Cycle (2009) 0.87

Emerging role of mitogen-activated protein kinases in peripheral neuropathies. J Peripher Nerv Syst (2007) 0.86

Expression of neural markers by undifferentiated rat mesenchymal stem cells. J Biomed Biotechnol (2012) 0.85

Anatomical organization of the telencephalic connections of the parafascicular nucleus in adult and developing rats. Eur J Neurosci (2003) 0.85