Published in Bioorg Med Chem Lett on November 12, 2010
The Discovery and Characterization of ML218: A Novel, Centrally Active T-Type Calcium Channel Inhibitor with Robust Effects in STN Neurons and in a Rodent Model of Parkinson's Disease. ACS Chem Neurosci (2011) 0.96
Identification of Potent and Selective Diphenylpropanamide RORγ Inhibitors. ACS Med Chem Lett (2013) 0.90
(E)-N-(3,3-Diphenyl-allyl-idene)-4-nitro-aniline. Acta Crystallogr Sect E Struct Rep Online (2012) 2.05
(E)-N-(3,3-Diphenyl-allyl-idene)-3-nitro-aniline. Acta Crystallogr Sect E Struct Rep Online (2012) 2.03
(E)-2,2'-[3-(2-Nitro-phen-yl)prop-2-ene-1,1-di-yl]bis-(3-hy-droxy-5,5-dimethyl-cyclo-hex-2-en-1-one). Acta Crystallogr Sect E Struct Rep Online (2011) 2.01
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3-Hy-droxy-2-[(2E)-1-(2-hy-droxy-6-oxocyclo-hex-1-en-1-yl)-3-(2-meth-oxy-phen-yl)prop-2-en-1-yl]cyclo-hex-2-en-1-one. Acta Crystallogr Sect E Struct Rep Online (2011) 1.54
2,2'-[(E)-3-(4-Nitro-phen-yl)prop-2-ene-1,1-di-yl]bis-(3-hy-droxy-5,5-dimethyl-cyclo-hex-2-en-1-one). Acta Crystallogr Sect E Struct Rep Online (2012) 1.28
9-[(E)-2-(2-Meth-oxy-phen-yl)ethen-yl]-3,4,5,6,7,9-hexa-hydro-2H-xanthene-1,8-dione. Acta Crystallogr Sect E Struct Rep Online (2012) 1.23
(E)-2,2'-[3-(4-Fluoro-phen-yl)prop-2-ene-1,1-di-yl]bis-(3-hy-droxy-5,5-dimethyl-cyclo-hex-2-en-1-one). Acta Crystallogr Sect E Struct Rep Online (2013) 1.16
(E)-3,3,6,6-Tetra-methyl-9-(2-nitro-styr-yl)-3,4,5,6,7,9-hexa-hydro-1H-xanthene-1,8(2H)-dione. Acta Crystallogr Sect E Struct Rep Online (2012) 1.11
(E)-N-[(E)-3-(4-Nitro-phen-yl)allyl-idene]naphthalen-1-amine. Acta Crystallogr Sect E Struct Rep Online (2013) 1.07
5- And 6-exocyclic products, cis-2,3,5-trisubstituted tetrahydrofurans, and cis-2,3,6-trisubstituted tetrahydropyrans via Prins-type cyclization. J Org Chem (2008) 1.06
(E)-9-(4-Chloro-styr-yl)-3,4,5,6,7,9-hexa-hydro-2H-xanthene-1,8-dione. Acta Crystallogr Sect E Struct Rep Online (2012) 1.06
(E)-2,2'-[3-(2-Nitro-phen-yl)prop-2-ene-1,1-di-yl]bis-(3-hy-droxy-cyclo-hex-2-en-1-one). Acta Crystallogr Sect E Struct Rep Online (2011) 1.02
Synthesis and biological evaluation of novel T-type Ca2+ channel blockers. Bioorg Med Chem (2004) 0.98
Novel GSK-3beta inhibitors from sequential virtual screening. Bioorg Med Chem (2007) 0.92
(E)-9-(4-Fluoro-styr-yl)-3,3,6,6-tetra-methyl-3,4,5,6,7,9-hexa-hydro-2H-xanthene-1,8-dione. Acta Crystallogr Sect E Struct Rep Online (2013) 0.92
5-Exocyclic products, 2,3,5-trisubstituted tetrahydrofurans via Prins-type cyclization. Org Lett (2006) 0.92
(E)-2,2'-[3-(4-Chloro-phen-yl)prop-2-ene-1,1-di-yl]bis-(3-hy-droxy-5,5-di-methyl-cyclo-hex-2-en-1-one). Acta Crystallogr Sect E Struct Rep Online (2013) 0.92
(E)-N-(3,3-Di-phenyl-allyl-idene)naph-thal-en-1-amine. Acta Crystallogr Sect E Struct Rep Online (2013) 0.91
(E)-N-(3,3-Di-phenyl-allyl-idene)-2-(tri-fluoro-meth-yl)aniline. Acta Crystallogr Sect E Struct Rep Online (2013) 0.90
Highly stereoselective synthesis of 2,5-disubstituted 3-vinylidene tetetrahydrofurans via Prins-type cyclization. Org Lett (2005) 0.88
Dispersant-free conducting pastes for flexible and printed nanocarbon electrodes. Nat Commun (2013) 0.87
Identification of tyrosinase inhibitors from Glycyrrhiza uralensis. Planta Med (2005) 0.87
Epigenetic regulation of cholinergic receptor M1 (CHRM1) by histone H3K9me3 impairs Ca(2+) signaling in Huntington's disease. Acta Neuropathol (2013) 0.86
Novel quinazolinone derivatives as 5-HT7 receptor ligands. Bioorg Med Chem (2007) 0.86
Development of selective blockers for Ca²(+)-activated Cl channel using Xenopus laevis oocytes with an improved drug screening strategy. Mol Brain (2008) 0.86
KST5468, a new T-type calcium channel antagonist, has an antinociceptive effect on inflammatory and neuropathic pain models. Pharmacol Biochem Behav (2010) 0.86
Arylpiperazine-containing pyrimidine 4-carboxamide derivatives targeting serotonin 5-HT(2A), 5-HT(2C), and the serotonin transporter as a potential antidepressant. Bioorg Med Chem Lett (2010) 0.85
A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3). Angew Chem Int Ed Engl (2015) 0.85
IKKbeta inhibitors identification part II: ligand and structure-based virtual screening. Bioorg Med Chem (2010) 0.85
Discovery and development of heat shock protein 90 inhibitors as anticancer agents: a review of patented potent geldanamycin derivatives. Expert Opin Ther Pat (2013) 0.84
Synthesis of 3,4-dimethylidene oxacycles through Prins-type cyclization of allenylmethylsilanes. Chem Asian J (2011) 0.84
Intramolecular Diels-Alder reactions of optically active allenic ketones: chirality transfer in the preparation of substituted oxa-bridged octalones. J Am Chem Soc (2005) 0.84
Synthesis and biological evaluation of novel T-type calcium channel blockers. Bioorg Med Chem Lett (2006) 0.82
A concise synthesis of tetrabenazine: an intramolecular aza-Prins-type cyclization via oxidative C-H activation. Org Lett (2011) 0.82
Novel pyrimidoazepine analogs as serotonin 5-HT(2A) and 5-HT(2C) receptor ligands for the treatment of obesity. Eur J Med Chem (2013) 0.81
Two new antioxidant stilbene dimers, parthenostilbenins A and B from Parthenocissus tricuspidata. Planta Med (2005) 0.81
Lead discovery and optimization of T-type calcium channel blockers. Bioorg Med Chem (2006) 0.80
IKKβ inhibitor identification: a multi-filter driven novel scaffold. BMC Bioinformatics (2010) 0.80
IKKbeta inhibitors identification part I: homology model assisted structure based virtual screening. Bioorg Med Chem (2009) 0.80
Direct synthesis of 4-fluoroisoxazoles through gold-catalyzed cascade cyclization-fluorination of 2-alkynone O-methyl oximes. J Org Chem (2014) 0.80
In silico renal clearance model using classical Volsurf approach. J Chem Inf Model (2006) 0.80
Synthesis and biological evaluation of chromone carboxamides as calpain inhibitors. Bioorg Med Chem Lett (2005) 0.80
Total synthesis and structural revision of (+/-)-tricholomalides A and B. J Am Chem Soc (2009) 0.80
First pharmacophoric hypothesis for T-type calcium channel blockers. Bioorg Med Chem (2004) 0.80
New serotonin 5-HT(6) ligands from common feature pharmacophore hypotheses. J Chem Inf Model (2007) 0.79
Functional human 5-HT6 receptor assay for high throughput screening of chemical ligands and binding proteins. Comb Chem High Throughput Screen (2008) 0.79
Discovery of piperidinyl aminopyrimidine derivatives as IKK-2 inhibitors. Bioorg Med Chem Lett (2011) 0.79
Synthesis and biological evaluation of 1,4-diazepane derivatives as T-type calcium channel blockers. Bioorg Med Chem Lett (2010) 0.79
Acremostrictin, a highly oxygenated metabolite from the marine fungus Acremonium strictum. J Nat Prod (2011) 0.79