Multiple functions of the S-phase checkpoint mediator.

Genetic instability is prevented by Mrc1-dependent spatio-temporal separation of replicative and repair activities of homologous recombination: homologous recombination tolerates replicative stress by Mrc1-regulated replication and repair activities operating at S and G2 in distinct subnuclear compartments. Bioessays (2014) 1.39

HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability. Nucleic Acids Res (2014) 0.86

Cdc7-dependent and -independent phosphorylation of Claspin in the induction of the DNA replication checkpoint. Cell Cycle (2013) 0.84

Multiple pathways can bypass the essential role of fission yeast Hsk1 kinase in DNA replication initiation. J Cell Biol (2011) 0.84

Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts. Cell Cycle (2012) 0.82

Cell cycle control in acute myeloid leukemia. Am J Cancer Res (2012) 0.82

Site-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1. PLoS Genet (2013) 0.81

Claspin as a biomarker of human papillomavirus-related high grade lesions of uterine cervix. J Transl Med (2012) 0.80

Conditional genetic interactions of RTT107, SLX4, and HRQ1 reveal dynamic networks upon DNA damage in S. cerevisiae. G3 (Bethesda) (2014) 0.79

Replicating damaged DNA in eukaryotes. Cold Spring Harb Perspect Biol (2013) 0.78

Proteasome-dependent degradation of replisome components regulates faithful DNA replication. Cell Cycle (2013) 0.78

The DNA-Binding Domain of S. pombe Mrc1 (Claspin) Acts to Enhance Stalling at Replication Barriers. PLoS One (2015) 0.76

MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR. Oncotarget (2016) 0.75

MRN- and 9-1-1-Independent Activation of the ATR-Chk1 Pathway during the Induction of the Virulence Program in the Phytopathogen Ustilago maydis. PLoS One (2015) 0.75

Cell-Type Specific Responses to DNA Replication Stress in Early C. elegans Embryos. PLoS One (2016) 0.75