PubRank

Rolf Jansen

Author PubWeight™ 42.48‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The RNA polymerase "switch region" is a target for inhibitors. Cell 2008 1.96
2 Opening and closing of the bacterial RNA polymerase clamp. Science 2012 1.73
3 Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase. EMBO J 2005 1.71
4 Chlorotonil A, a macrolide with a unique gem-dichloro-1,3-dione functionality from Sorangium cellulosum, So ce1525. Angew Chem Int Ed Engl 2008 1.43
5 New target for inhibition of bacterial RNA polymerase: 'switch region'. Curr Opin Microbiol 2011 1.26
6 Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase. J Neurosci 2011 1.26
7 Rifamycins do not function by allosteric modulation of binding of Mg2+ to the RNA polymerase active center. Proc Natl Acad Sci U S A 2008 1.16
8 Hepatitis C virus complete life cycle screen for identification of small molecules with pro- or antiviral activity. Antiviral Res 2010 1.12
9 Carbamidocyclophanes A-E, chlorinated paracyclophanes with cytotoxic and antibiotic activity from the Vietnamese cyanobacterium Nostoc sp. J Nat Prod 2007 1.09
10 GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife 2014 1.09
11 Streptococcus mutans inhibits Candida albicans hyphal formation by the fatty acid signaling molecule trans-2-decenoic acid (SDSF). Chembiochem 2010 1.08
12 Archazolid and apicularen: novel specific V-ATPase inhibitors. BMC Biochem 2005 1.06
13 Lyngbyazothrins A-D, antimicrobial cyclic undecapeptides from the cultured Cyanobacterium lyngbya sp. J Nat Prod 2009 1.06
14 7-O-malonyl macrolactin A, a new macrolactin antibiotic from Bacillus subtilis active against methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, and a small-colony variant of Burkholderia cepacia. Antimicrob Agents Chemother 2006 1.04
15 Stereochemical determination and complex biosynthetic assembly of etnangien, a highly potent RNA polymerase inhibitor from the myxobacterium Sorangium cellulosum. J Am Chem Soc 2008 0.98
16 Elansolid A, a unique macrolide antibiotic from Chitinophaga sancti isolated as two stable atropisomers. Angew Chem Int Ed Engl 2011 0.93
17 The absolute configuration of rhizopodin and its inhibition of actin polymerization by dimerization. Angew Chem Int Ed Engl 2009 0.91
18 Balticols A-F, new naphthalenone derivatives with antiviral activity, from an ascomycetous fungus. Chem Biodivers 2009 0.91
19 Gephyronic acid, a missing link between polyketide inhibitors of eukaryotic protein synthesis (part I): Structural revision and stereochemical assignment of gephyronic acid. Angew Chem Int Ed Engl 2010 0.90
20 Chondramide C: synthesis, configurational assignment, and structure-activity relationship studies. Angew Chem Int Ed Engl 2008 0.89
21 Marinoquinolines A-F, pyrroloquinolines from Ohtaekwangia kribbensis (Bacteroidetes). J Nat Prod 2011 0.89
22 Rhamnolipids from the rhizosphere bacterium Pseudomonas sp. GRP(3) that reduces damping-off disease in Chilli and tomato nurseries. J Nat Prod 2007 0.88
23 Precursor-directed syntheses and biological evaluation of new elansolid derivatives. Chembiochem 2012 0.87
24 Roimatacene: an antibiotic against Gram-negative bacteria isolated from Cystobacter ferrugineus Cb G35 (Myxobacteria). Chemistry 2011 0.87
25 Cyclic depsipeptides, ichthyopeptins A and B, from Microcystis ichthyoblabe. J Nat Prod 2007 0.85
26 Etnangien, a macrolide-polyene antibiotic from Sorangium cellulosum that inhibits nucleic acid polymerases. J Nat Prod 2007 0.85
27 Molecular basis of elansolid biosynthesis: evidence for an unprecedented quinone methide initiated intramolecular Diels-Alder cycloaddition/macrolactonization. Angew Chem Int Ed Engl 2011 0.84
28 Indiacens A and B: prenyl indoles from the myxobacterium Sandaracinus amylolyticus. J Nat Prod 2012 0.84
29 Disciformycins A and B: 12-membered macrolide glycoside antibiotics from the myxobacterium Pyxidicoccus fallax active against multiresistant staphylococci. Angew Chem Int Ed Engl 2014 0.82
30 p-hydroxyacetophenone amides from Cystobacter ferrugineus, strain Cb G35. J Nat Prod 2011 0.82
31 Cohaerins G-K, azaphilone pigments from Annulohypoxylon cohaerens and absolute stereochemistry of cohaerins C-K. Phytochemistry 2013 0.81
32 Gephyronic acid, a missing link between polyketide inhibitors of eukaryotic protein synthesis (part II): Total synthesis of gephyronic acid. Angew Chem Int Ed Engl 2010 0.81
33 [Prescription of generic drugs in general practice. Results of a survey of general practitioners]. Med Klin (Munich) 2006 0.80
34 Chivosazole A--elucidation of the absolute and relative configuration. Angew Chem Int Ed Engl 2007 0.79
35 Ajudazols, new inhibitors of the mitochondrial electron transport from Chondromyces crocatus. Production, antimicrobial activity and mechanism of action. J Antibiot (Tokyo) 2004 0.79
36 The thuggacins, novel antibacterial macrolides from Sorangium cellulosum acting against selected Gram-positive bacteria. J Antibiot (Tokyo) 2007 0.78
37 Identification of myxobacteria-derived HIV inhibitors by a high-throughput two-step infectivity assay. Microb Cell Fact 2013 0.78
38 Antimycobacterial serratamolides and diacyl peptoglucosamine derivatives from Serratia sp. J Nat Prod 2008 0.78
39 The binding site of the V-ATPase inhibitor apicularen is in the vicinity of those for bafilomycin and archazolid. J Biol Chem 2012 0.77
40 Binding mode characterization of novel RNA polymerase inhibitors using a combined biochemical and NMR approach. ACS Chem Biol 2014 0.77
41 Concerted action of P450 plus helper protein to form the amino-hydroxy-piperidone moiety of the potent protease inhibitor crocapeptin. J Am Chem Soc 2013 0.77
42 Isolation and total synthesis of icumazoles and noricumazoles--antifungal antibiotics and cation-channel blockers from Sorangium cellulosum. Angew Chem Int Ed Engl 2011 0.77
43 Thuggacins, macrolide antibiotics active against Mycobacterium tuberculosis: isolation from myxobacteria, structure elucidation, conformation analysis and biosynthesis. Chemistry 2007 0.76
44 Chivosazoles A and F, cytostatic macrolides from myxobacteria, interfere with actin. Chembiochem 2009 0.75
45 Sulfangolids, macrolide sulfate esters from Sorangium cellulosum. Chemistry 2012 0.75
46 Total synthesis of noricumazole B establishes D-arabinose as glycan unit. Org Biomol Chem 2012 0.75
47 Total and semi-syntheses of antimicrobial thuggacin derivatives. Chemistry 2015 0.75
48 Hyafurones, hyapyrrolines, and hyapyrones: polyketides from Hyalangium minutum. J Nat Prod 2014 0.75
49 Hyaladione, an S-methyl cyclohexadiene-dione from Hyalangium minutum. J Nat Prod 2012 0.75