1
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Fibrinolysis for patients with intermediate-risk pulmonary embolism.
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N Engl J Med
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9.33
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2
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Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials.
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Lancet Neurol
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2007
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6.15
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3
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Extended-duration venous thromboembolism prophylaxis in acutely ill medical patients with recently reduced mobility: a randomized trial.
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Ann Intern Med
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2010
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5.79
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4
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Etomidate versus ketamine for rapid sequence intubation in acutely ill patients: a multicentre randomised controlled trial.
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Lancet
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2009
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5.31
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5
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Prehospital ticagrelor in ST-segment elevation myocardial infarction.
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N Engl J Med
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2014
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5.25
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6
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Family presence during cardiopulmonary resuscitation.
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N Engl J Med
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2013
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4.74
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7
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Updated systematic review and meta-analysis of randomized clinical trials on the role of mechanical bowel preparation before colorectal surgery.
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Ann Surg
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2009
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4.66
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8
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Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4).
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Pain
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2005
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4.59
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9
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Bedside monitoring to adjust antiplatelet therapy for coronary stenting.
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N Engl J Med
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2012
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4.37
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10
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Explosion of tuberculin-specific Th1-responses induces immune restoration syndrome in tuberculosis and HIV co-infected patients.
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AIDS
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2006
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3.82
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11
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Magnetic resonance elastography for the noninvasive staging of liver fibrosis.
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Gastroenterology
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2008
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3.67
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12
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Impact of continuous venovenous hemofiltration on organ failure during the early phase of severe sepsis: a randomized controlled trial.
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Crit Care Med
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2009
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3.23
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13
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Effect of waxy maize-derived hydroxyethyl starch 130/0.4 on renal function in surgical patients.
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Anesthesiology
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2013
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3.13
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14
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STEMI and NSTEMI: are they so different? 1 year outcomes in acute myocardial infarction as defined by the ESC/ACC definition (the OPERA registry).
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Eur Heart J
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2007
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3.03
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15
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Radiofrequency ablation of hepatocellular carcinoma: long-term results and prognostic factors in 235 Western patients with cirrhosis.
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Hepatology
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2009
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3.01
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16
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Decompressive craniectomy and early cranioplasty for the management of severe head injury: a prospective multicenter study on 147 patients.
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World Neurosurg
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2011
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2.89
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17
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Photoselective vaporization of the prostate with GreenLight 120-W laser compared with monopolar transurethral resection of the prostate: a multicenter randomized controlled trial.
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Eur Urol
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2012
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2.80
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18
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Immediate vs delayed intervention for acute coronary syndromes: a randomized clinical trial.
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JAMA
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2.72
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19
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Fibered confocal fluorescence microscopy (Cell-viZio) facilitates extended imaging in the field of microcirculation. A comparison with intravital microscopy.
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2.66
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20
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Synergistic deleterious effect of hypoxemia and hypovolemia on microcirculation in intestinal villi*.
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Crit Care Med
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2.65
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21
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Sequential-design, multicenter, randomized, controlled trial of early decompressive craniectomy in malignant middle cerebral artery infarction (DECIMAL Trial).
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Stroke
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2007
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2.62
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22
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Impact of metformin on the prognosis of cirrhosis induced by viral hepatitis C in diabetic patients.
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J Clin Endocrinol Metab
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2011
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2.48
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23
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High incidence of myocardial ischemia during postpartum hemorrhage.
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Anesthesiology
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2004
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2.16
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24
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Placebo-controlled trial of high-dose atorvastatin in patients with severe cerebral small vessel disease.
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Stroke
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2009
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2.10
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25
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Out-of-hospital tracheal intubation with single-use versus reusable metal laryngoscope blades: a multicenter randomized controlled trial.
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Ann Emerg Med
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2.02
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26
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Spironolactone reduces fibrosis of dilated atria during heart failure in rats with myocardial infarction.
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Eur Heart J
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1.99
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27
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Mortality after colorectal cancer surgery: a French survey of more than 84,000 patients.
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Ann Surg
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28
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The capacity of nondigestible carbohydrates to stimulate fecal bifidobacteria in healthy humans: a double-blind, randomized, placebo-controlled, parallel-group, dose-response relation study.
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Am J Clin Nutr
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2004
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1.82
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29
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Impaired tissue perfusion: a pathology common to hypertension, obesity, and diabetes mellitus.
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Circulation
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30
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Microcirculatory alterations in traumatic hemorrhagic shock.
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Crit Care Med
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2014
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1.80
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31
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Intravenous enoxaparin or unfractionated heparin in primary percutaneous coronary intervention for ST-elevation myocardial infarction: the international randomised open-label ATOLL trial.
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Lancet
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2011
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1.80
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32
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Rectal cancer surgery with or without bowel preparation: The French GRECCAR III multicenter single-blinded randomized trial.
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Ann Surg
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1.67
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33
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Involvement of renin-angiotensin system in pressure-flow relationship: role of angiotensin-converting enzyme gene polymorphism.
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Anesthesiology
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2002
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1.62
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34
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Suboccipital steroid injections for transitional treatment of patients with more than two cluster headache attacks per day: a randomised, double-blind, placebo-controlled trial.
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Lancet Neurol
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2011
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1.58
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35
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Improved survival after resuscitation with norepinephrine in a murine model of uncontrolled hemorrhagic shock.
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Anesthesiology
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2007
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1.58
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36
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Plasma-induced endothelial oxidative stress is related to the severity of septic shock.
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Crit Care Med
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1.57
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37
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Real-time magnetic resonance-guided laser thermal therapy for focal metastatic brain tumors.
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Neurosurgery
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2008
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1.57
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38
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Axon-tracing properties of indocyanine green.
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Arch Ophthalmol
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1.55
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39
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Both passive leg raising and intravascular volume expansion improve sublingual microcirculatory perfusion in severe sepsis and septic shock patients.
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Intensive Care Med
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1.55
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40
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Genotype-phenotype correlations in cerebral cavernous malformations patients.
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Ann Neurol
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1.55
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41
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Reliance on visual information after stroke. Part I: Balance on dynamic posturography.
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Arch Phys Med Rehabil
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2004
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1.52
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42
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Carotid intima-media thickness, plaques, and Framingham risk score as independent determinants of stroke risk.
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Stroke
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2005
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1.52
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43
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Efficacy and safety of enoxaparin versus unfractionated heparin during percutaneous coronary intervention: systematic review and meta-analysis.
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BMJ
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1.51
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A randomized study of out-of-hospital continuous positive airway pressure for acute cardiogenic pulmonary oedema: physiological and clinical effects.
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1.49
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45
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Postresuscitation syndrome: potential role of hydroxyl radical-induced endothelial cell damage.
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46
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Survival after radiofrequency ablation and salvage transplantation in patients with hepatocellular carcinoma and Child-Pugh A cirrhosis.
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1.46
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Effects of vasopressin, norepinephrine, and L-arginine on intestinal microcirculation in endotoxemia.
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1.46
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48
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Atorvastatin decreases computed tomography and S100-assessed brain ischemia after subarachnoid aneurysmal hemorrhage: a comparative study.
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Crit Care Med
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1.45
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49
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Value of lactic acidosis in the assessment of the severity of acute cyanide poisoning.
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Crit Care Med
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1.42
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50
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Efficacy of joint lavage in knee osteoarthritis: meta-analysis of randomized controlled studies.
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Rheumatology (Oxford)
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1.40
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51
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Blood pressure and haemoglobin A1c are associated with microhaemorrhage in CADASIL: a two-centre cohort study.
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Brain
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1.38
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52
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Renal arterial resistance in septic shock: effects of increasing mean arterial pressure with norepinephrine on the renal resistive index assessed with Doppler ultrasonography.
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Intensive Care Med
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1.38
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53
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Tuberculosis-associated immune restoration syndrome in HIV-1-infected patients involves tuberculin-specific CD4 Th1 cells and KIR-negative gammadelta T cells.
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J Immunol
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54
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Pretreatment with prasugrel in non-ST-segment elevation acute coronary syndromes.
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N Engl J Med
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55
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Benefits of massive weight loss on symptoms, systemic inflammation and cartilage turnover in obese patients with knee osteoarthritis.
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Ann Rheum Dis
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1.27
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56
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Reliance on visual information after stroke. Part II: Effectiveness of a balance rehabilitation program with visual cue deprivation after stroke: a randomized controlled trial.
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1.23
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57
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Structural and hemodynamic analysis of the mouse retinal microcirculation.
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Invest Ophthalmol Vis Sci
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58
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Risk factors for intra-abdominal septic complications after a first ileocecal resection for Crohn's disease: a multivariate analysis in 161 consecutive patients.
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Dis Colon Rectum
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Abciximab in primary coronary stenting of ST-elevation myocardial infarction: a European meta-analysis on individual patients' data with long-term follow-up.
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A randomized controlled trial of alleviated positioning after small macular hole surgery.
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Ophthalmology
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61
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Endovascular treatment of basilar tip aneurysms with Guglielmi detachable coils: predictors of immediate and long-term results with multivariate analysis 6-year experience.
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Radiology
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1.17
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62
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Evaluation of an impedance threshold device in patients receiving active compression-decompression cardiopulmonary resuscitation for out of hospital cardiac arrest.
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Resuscitation
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63
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Treatment of shoulder pain in spastic hemiplegia by reducing spasticity of the subscapular muscle: a randomised, double blind, placebo controlled study of botulinum toxin A.
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J Neurol Neurosurg Psychiatry
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Laser thermal therapy: real-time MRI-guided and computer-controlled procedures for metastatic brain tumors.
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Anesth Analg
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Perception of verticality after recent cerebral hemispheric stroke.
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Stroke
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1.11
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67
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Inflammatory cytokines, C reactive protein, and procalcitonin as early predictors of necrosis infection in acute necrotizing pancreatitis.
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Hypomagnesemia associated with chondrocalcinosis: a cross-sectional study.
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Arthritis Rheum
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Randomized comparison of platelet function monitoring to adjust antiplatelet therapy versus standard of care: rationale and design of the assessment with a double randomization of (1) a fixed dose versus a monitoring-guided dose of aspirin and clopidogrel after DES implantation, and (2) treatment interruption versus continuation, 1 year after stenting (ARCTIC) study.
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Am Heart J
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MR elastography of liver fibrosis: preliminary results comparing spin-echo and echo-planar imaging.
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Erythromycin infusion or gastric lavage for upper gastrointestinal bleeding: a multicenter randomized controlled trial.
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The AFC score: validation of a 4-item predicting score of postoperative mortality after colorectal resection for cancer or diverticulitis: results of a prospective multicenter study in 1049 patients.
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Am Heart J
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Cardiac troponin I is an independent predictor of in-hospital death after adult cardiac surgery.
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Tumor necrosis factor-alpha increases airway smooth muscle oxidants production through a NADPH oxidase-like system to enhance myosin light chain phosphorylation and contractility.
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Hyaline cartilage thickness in radiographically normal cadaveric hips: comparison of spiral CT arthrographic and macroscopic measurements.
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Characterization and prediction of prolonged air leak after pulmonary resection: a nationwide study setting up the index of prolonged air leak.
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Prospective comparative assessment of buprenorphine overdose with heroin and methadone: clinical characteristics and response to antidotal treatment.
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