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1
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Implications of small effect sizes of individual genetic variants on the design and interpretation of genetic association studies of complex diseases.
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Am J Epidemiol
|
2006
|
7.66
|
|
2
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'Racial' differences in genetic effects for complex diseases.
|
Nat Genet
|
2004
|
5.15
|
|
3
|
Early extreme contradictory estimates may appear in published research: the Proteus phenomenon in molecular genetics research and randomized trials.
|
J Clin Epidemiol
|
2005
|
4.14
|
|
4
|
An exploratory test for an excess of significant findings.
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Clin Trials
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2007
|
3.83
|
|
5
|
Vitamin D with or without calcium supplementation for prevention of cancer and fractures: an updated meta-analysis for the U.S. Preventive Services Task Force.
|
Ann Intern Med
|
2011
|
3.71
|
|
6
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Vitamin D and calcium: a systematic review of health outcomes.
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Evid Rep Technol Assess (Full Rep)
|
2009
|
3.51
|
|
7
|
Genetic associations in large versus small studies: an empirical assessment.
|
Lancet
|
2003
|
3.41
|
|
8
|
The appropriateness of asymmetry tests for publication bias in meta-analyses: a large survey.
|
CMAJ
|
2007
|
3.40
|
|
9
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Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis.
|
Am J Gastroenterol
|
2004
|
3.28
|
|
10
|
Meta-Analyst: software for meta-analysis of binary, continuous and diagnostic data.
|
BMC Med Res Methodol
|
2009
|
2.92
|
|
11
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Statins, low-density lipoprotein cholesterol, and risk of cancer.
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J Am Coll Cardiol
|
2008
|
2.77
|
|
12
|
Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis.
|
JAMA
|
2008
|
2.52
|
|
13
|
Local literature bias in genetic epidemiology: an empirical evaluation of the Chinese literature.
|
PLoS Med
|
2005
|
2.18
|
|
14
|
Systematic review: charged-particle radiation therapy for cancer.
|
Ann Intern Med
|
2009
|
2.15
|
|
15
|
A summary of the Agency for Healthcare Research and Quality's evidence report on breastfeeding in developed countries.
|
Breastfeed Med
|
2009
|
2.09
|
|
16
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Semi-automated screening of biomedical citations for systematic reviews.
|
BMC Bioinformatics
|
2010
|
2.00
|
|
17
|
Quantitative evaluation of drug or device effects on ventricular remodeling as predictors of therapeutic effects on mortality in patients with heart failure and reduced ejection fraction: a meta-analytic approach.
|
J Am Coll Cardiol
|
2010
|
1.93
|
|
18
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Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study.
|
Lancet Neurol
|
2006
|
1.92
|
|
19
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Limited benefit of antiretroviral resistance testing in treatment-experienced patients: a meta-analysis.
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AIDS
|
2004
|
1.87
|
|
20
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Do statins impair cognition? A systematic review and meta-analysis of randomized controlled trials.
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J Gen Intern Med
|
2015
|
1.74
|
|
21
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Dose of erythropoiesis-stimulating agents and adverse outcomes in CKD: a metaregression analysis.
|
Am J Kidney Dis
|
2012
|
1.69
|
|
22
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Systematic review: Anti-epidermal growth factor receptor treatment effect modification by KRAS mutations in advanced colorectal cancer.
|
Ann Intern Med
|
2011
|
1.68
|
|
23
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Do observational studies using propensity score methods agree with randomized trials? A systematic comparison of studies on acute coronary syndromes.
|
Eur Heart J
|
2012
|
1.64
|
|
24
|
Heterogeneity of the phenotypic definition of coronary artery disease and its impact on genetic association studies.
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Circ Cardiovasc Genet
|
2010
|
1.62
|
|
25
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Unavailability of online supplementary scientific information from articles published in major journals.
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FASEB J
|
2005
|
1.61
|
|
26
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Automatically annotating topics in transcripts of patient-provider interactions via machine learning.
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Med Decis Making
|
2013
|
1.51
|
|
27
|
Hereditary nonpolyposis colorectal cancer: diagnostic strategies and their implications.
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Evid Rep Technol Assess (Full Rep)
|
2007
|
1.42
|
|
28
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Oral Mechanical Bowel Preparation for Colorectal Surgery: Systematic Review and Meta-Analysis.
|
Dis Colon Rectum
|
2015
|
1.37
|
|
29
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Role of the Fcgamma receptor IIa polymorphism in susceptibility to systemic lupus erythematosus and lupus nephritis: a meta-analysis.
|
Arthritis Rheum
|
2002
|
1.37
|
|
30
|
The COPD genetic association compendium: a comprehensive online database of COPD genetic associations.
|
Hum Mol Genet
|
2009
|
1.35
|
|
31
|
Impact of schizophrenia candidate genes on schizotypy and cognitive endophenotypes at the population level.
|
Biol Psychiatry
|
2007
|
1.32
|
|
32
|
Association of polymorphisms of the estrogen receptor alpha gene with bone mineral density and fracture risk in women: a meta-analysis.
|
J Bone Miner Res
|
2002
|
1.29
|
|
33
|
Patellar resurfacing in total knee arthroplasty. A meta-analysis.
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J Bone Joint Surg Am
|
2005
|
1.29
|
|
34
|
Extreme between-study homogeneity in meta-analyses could offer useful insights.
|
J Clin Epidemiol
|
2006
|
1.28
|
|
35
|
Comparison of the diagnostic accuracy of lymphatic endothelium markers: Bayesian approach.
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Mod Pathol
|
2005
|
1.25
|
|
36
|
Conducting quantitative synthesis when comparing medical interventions: AHRQ and the Effective Health Care Program.
|
J Clin Epidemiol
|
2011
|
1.24
|
|
37
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Data extraction from machine-translated versus original language randomized trial reports: a comparative study.
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Syst Rev
|
2013
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1.18
|
|
38
|
Inflated numbers of authors over time have not been just due to increasing research complexity.
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J Clin Epidemiol
|
2008
|
1.17
|
|
39
|
Family-based versus unrelated case-control designs for genetic associations.
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PLoS Genet
|
2006
|
1.15
|
|
40
|
The Fc gamma RIIIA-F158 allele is a risk factor for the development of lupus nephritis: a meta-analysis.
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Kidney Int
|
2003
|
1.13
|
|
41
|
The empirical basis for determinations of medical futility.
|
J Gen Intern Med
|
2010
|
1.13
|
|
42
|
Bayesian meta-analysis and meta-regression for gene-disease associations and deviations from Hardy-Weinberg equilibrium.
|
Stat Med
|
2007
|
1.09
|
|
43
|
Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study.
|
Bone
|
2007
|
1.07
|
|
44
|
Selective discussion and transparency in microarray research findings for cancer outcomes.
|
Eur J Cancer
|
2007
|
1.06
|
|
45
|
Toward modernizing the systematic review pipeline in genetics: efficient updating via data mining.
|
Genet Med
|
2012
|
1.04
|
|
46
|
Modernizing the systematic review process to inform comparative effectiveness: tools and methods.
|
J Comp Eff Res
|
2013
|
1.02
|
|
47
|
Electrocardiogram screening for disorders that cause sudden cardiac death in asymptomatic children: a meta-analysis.
|
Pediatrics
|
2012
|
1.02
|
|
48
|
Electrocardiogram-gated single-photon emission computed tomography versus cardiac magnetic resonance imaging for the assessment of left ventricular volumes and ejection fraction: a meta-analysis.
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J Am Coll Cardiol
|
2002
|
1.02
|
|
49
|
Patent foramen ovale and cryptogenic stroke.
|
N Engl J Med
|
2008
|
1.00
|
|
50
|
Therapeutic innovations, diminishing returns, and control rate preservation.
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JAMA
|
2009
|
1.00
|
|
51
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Are unadjusted analyses of clinical trials inappropriately biased toward the null?
|
Stroke
|
2009
|
0.95
|
|
52
|
The role of FcgammaRIIA and IIIA polymorphisms in autoimmune diseases.
|
Biomed Pharmacother
|
2004
|
0.95
|
|
53
|
Risk of arrhythmic and nonarrhythmic death in patients with heart failure and chronic kidney disease.
|
Am Heart J
|
2011
|
0.95
|
|
54
|
Paraoxonase 1 polymorphisms and ischemic stroke risk: A systematic review and meta-analysis.
|
Genet Med
|
2010
|
0.94
|
|
55
|
Comparison of large versus smaller randomized trials for mental health-related interventions.
|
Am J Psychiatry
|
2005
|
0.93
|
|
56
|
Reporting of systematic reviews of micronutrients and health: a critical appraisal.
|
Am J Clin Nutr
|
2009
|
0.93
|
|
57
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Evidence from crossover trials: empirical evaluation and comparison against parallel arm trials.
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Int J Epidemiol
|
2007
|
0.93
|
|
58
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Statistical considerations in meta-analysis.
|
Infect Dis Clin North Am
|
2009
|
0.92
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59
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Genotype misclassification in genetic association studies of the rs1042522 TP53 (Arg72Pro) polymorphism: a systematic review of studies of breast, lung, colorectal, ovarian, and endometrial cancer.
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Am J Epidemiol
|
2013
|
0.92
|
|
60
|
Prosthesis infection: diagnosis after total joint arthroplasty with antigranulocyte scintigraphy with 99mTc-labeled monoclonal antibodies--a meta-analysis.
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Radiology
|
2006
|
0.90
|
|
61
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Opportunities and challenges in conducting systematic reviews to support the development of nutrient reference values: vitamin A as an example.
|
Am J Clin Nutr
|
2009
|
0.90
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62
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Reexamining the emperor's new clothes: ambiguities in current cardiac screening recommendations for youth with attention deficit hyperactivity disorder.
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Circ Cardiovasc Qual Outcomes
|
2008
|
0.90
|
|
63
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Are "treatment" bare metal stents superior to "control" bare metal stents? A meta-analytic approach.
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Am Heart J
|
2008
|
0.87
|
|
64
|
HIV lipodystrophy case definition using artificial neural network modelling.
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Antivir Ther
|
2003
|
0.86
|
|
65
|
Parity and risk of lung cancer in women: systematic review and meta-analysis of epidemiological studies.
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Lung Cancer
|
2011
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0.83
|
|
66
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Comparative efficacy of first-line therapies for advanced-stage chronic lymphocytic leukemia: a multiple-treatment meta-analysis.
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Cancer Treat Rev
|
2012
|
0.83
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|
67
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CYP2D6 testing to predict response to tamoxifen in women with breast cancer. Pharmacogenomic.
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PLoS Curr
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2010
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0.83
|
|
68
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Meta-analysis of genome-wide linkage scans for renal function traits.
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Nephrol Dial Transplant
|
2011
|
0.81
|
|
69
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Association of RGS4 variants with schizotypy and cognitive endophenotypes at the population level.
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Behav Brain Funct
|
2008
|
0.81
|
|
70
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Self-reported health in high and very high incomes.
|
Qual Life Res
|
2006
|
0.80
|
|
71
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BCR-ABL mutation testing to predict response to tyrosine kinase inhibitors in patients with chronic myeloid leukemia.
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PLoS Curr
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2010
|
0.79
|
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72
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Impact of quality of evidence on the strength of recommendations: an empirical study.
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BMC Health Serv Res
|
2009
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0.77
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73
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Seeing the forests and the trees--innovative approaches to exploring heterogeneity in systematic reviews of complex interventions to enhance health system decision-making: a protocol.
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Syst Rev
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2014
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0.77
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74
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Drug and device effects on peak oxygen consumption, 6-minute walk distance, and natriuretic peptides as predictors of therapeutic effects on mortality in patients with heart failure and reduced ejection fraction.
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Circ Heart Fail
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2011
|
0.77
|
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75
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Cranial radiation for pediatric T-lineage acute lymphoblastic leukemia: a systematic review and meta-analysis.
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Am J Hematol
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2014
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0.77
|
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76
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A lesson from the Zuni Indians: heritability in perspective.
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Am J Kidney Dis
|
2010
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0.76
|
|
77
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Empirical evaluation of meta-analytic approaches for nutrient and health outcome dose-response data.
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Res Synth Methods
|
2013
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0.75
|
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78
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Inconsistencies in a study of rifampicin-miconazole-impregnated catheters versus standard catheters.
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Clin Infect Dis
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2009
|
0.75
|
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79
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Commentary: On Effect Measures, Heterogeneity, and the Laws of Nature.
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Epidemiology
|
2015
|
0.75
|
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80
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Reply to Badri et al. on 'Limited benefit of antiretroviral resistance testing in treatment-experienced patients: a meta-analysis'.
|
AIDS
|
2005
|
0.75
|
|
81
|
Diagnosis of sensorineural hearing loss with neural networks versus logistic regression modeling of distortion product otoacoustic emissions.
|
Audiol Neurootol
|
2004
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0.75
|
|
82
|
PROPENSITY SCORE-BASED METHODS IN COMPARATIVE EFFECTIVENESS RESEARCH ON CORONARY ARTERY DISEASE.
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Am J Epidemiol
|
2017
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0.75
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