Published in J Mol Cell Cardiol on December 29, 2010
Therapeutic efficacy of AAV1.SERCA2a in monocrotaline-induced pulmonary arterial hypertension. Circulation (2013) 1.05
Orai1 calcium channels in the vasculature. Pflugers Arch (2012) 0.95
ORAI1 calcium channel orchestrates skin homeostasis. Proc Natl Acad Sci U S A (2013) 0.93
Urotensin-II promotes vascular smooth muscle cell proliferation through store-operated calcium entry and EGFR transactivation. Cardiovasc Res (2013) 0.90
Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration. Pflugers Arch (2012) 0.88
SERCA2a gene transfer prevents intimal proliferation in an organ culture of human internal mammary artery. Gene Ther (2012) 0.87
Efficient transduction of vascular smooth muscle cells with a translational AAV2.5 vector: a new perspective for in-stent restenosis gene therapy. Gene Ther (2013) 0.83
CCR5 as a treatment target in pulmonary arterial hypertension. Circulation (2014) 0.83
Pan-junctional sarcoplasmic reticulum in vascular smooth muscle: nanospace Ca2+ transport for site- and function-specific Ca2+ signalling. J Physiol (2013) 0.81
Orai channel-mediated Ca2+ signals in vascular and airway smooth muscle. Am J Physiol Cell Physiol (2015) 0.78
Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis. Biochim Biophys Acta (2014) 0.77
STIM1-dependent Ca(2+) microdomains are required for myofilament remodeling and signaling in the heart. Sci Rep (2016) 0.75
ASIC1-mediated calcium entry stimulates NFATc3 nuclear translocation via PICK1 coupling in pulmonary arterial smooth muscle cells. Am J Physiol Lung Cell Mol Physiol (2016) 0.75
Importance of Altered Levels of SERCA, IP3R, and RyR in Vascular Smooth Muscle Cell. Biophys J (2017) 0.75
Effects of cyclopiazonic acid and dexamethasone on serotonin-induced calcium responses in vascular smooth muscle cells. J Physiol Biochem (2016) 0.75
Inositol trisphosphate and calcium signalling. Nature (1993) 25.57
Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev (2004) 16.52
Differential activation of transcription factors induced by Ca2+ response amplitude and duration. Nature (1997) 9.99
Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1. J Biol Chem (2006) 5.32
The molecular choreography of a store-operated calcium channel. Nature (2007) 4.80
Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A. Science (1999) 4.20
2-aminoethoxydiphenyl borate (2-APB) is a reliable blocker of store-operated Ca2+ entry but an inconsistent inhibitor of InsP3-induced Ca2+ release. FASEB J (2002) 3.60
The intima. Soil for atherosclerosis and restenosis. Circ Res (1995) 3.48
Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a. Circulation (1999) 3.19
Inositol trisphosphate and calcium signalling mechanisms. Biochim Biophys Acta (2008) 2.66
Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT. Mol Cell (1998) 2.44
Evidence for STIM1- and Orai1-dependent store-operated calcium influx through ICRAC in vascular smooth muscle cells: role in proliferation and migration. FASEB J (2009) 2.36
Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes. Cell Calcium (2007) 2.23
Arterial smooth muscle cell heterogeneity: implications for atherosclerosis and restenosis development. Arterioscler Thromb Vasc Biol (2003) 2.17
Inhibition of endogenous TRP1 decreases capacitative Ca2+ entry and attenuates pulmonary artery smooth muscle cell proliferation. Am J Physiol Lung Cell Mol Physiol (2002) 2.13
Smooth muscle cell calcium activation mechanisms. J Physiol (2008) 2.12
Ca2+ handling is altered when arterial myocytes progress from a contractile to a proliferative phenotype in culture. Am J Physiol Cell Physiol (2008) 2.01
Mechanisms underlying heterogeneous Ca2+ sparklet activity in arterial smooth muscle. J Gen Physiol (2006) 1.86
Modulation of the molecular composition of large conductance, Ca(2+) activated K(+) channels in vascular smooth muscle during hypertension. J Clin Invest (2003) 1.79
Biochemical evidence for a complex involving dihydropyridine receptor and ryanodine receptor in triad junctions of skeletal muscle. Proc Natl Acad Sci U S A (1994) 1.78
The non-excitable smooth muscle: calcium signaling and phenotypic switching during vascular disease. Pflugers Arch (2008) 1.72
Excitation-transcription coupling in arterial smooth muscle. Circ Res (2006) 1.70
Spatial and temporal signalling by calcium. Curr Opin Cell Biol (1994) 1.54
ORAI and store-operated calcium influx in human airway smooth muscle cells. Am J Respir Cell Mol Biol (2008) 1.50
The control of Ca2+ influx and NFATc3 signaling in arterial smooth muscle during hypertension. Proc Natl Acad Sci U S A (2008) 1.38
A definition of the intima of human arteries and of its atherosclerosis-prone regions. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Arterioscler Thromb (1992) 1.38
Multiple activation mechanisms of store-operated TRPC channels in smooth muscle cells. J Physiol (2007) 1.37
RNA interference targeting STIM1 suppresses vascular smooth muscle cell proliferation and neointima formation in the rat. Mol Ther (2008) 1.36
Blockade of nuclear factor of activated T cells activation signaling suppresses balloon injury-induced neointima formation in a rat carotid artery model. J Biol Chem (2005) 1.33
Sarco/endoplasmic reticulum Ca2+-ATPase gene transfer reduces vascular smooth muscle cell proliferation and neointima formation in the rat. Circ Res (2005) 1.33
Gene transfer into normal and atherosclerotic human blood vessels. Circ Res (1998) 1.24
Inositol trisphosphate and calcium oscillations. Biochem Soc Symp (2007) 1.22
Functional role of stromal interaction molecule 1 (STIM1) in vascular smooth muscle cells. Biochem Biophys Res Commun (2007) 1.21
L-type calcium channel expression depends on the differentiated state of vascular smooth muscle cells. FASEB J (1998) 1.20
SERCA2a gene transfer enhances eNOS expression and activity in endothelial cells. Mol Ther (2010) 1.18
Expression of endoplasmic-reticulum Ca2(+)-pump isoforms and of phospholamban in pig smooth-muscle tissues. Biochem J (1990) 1.18
Role of phospholamban in the modulation of arterial Ca(2+) sparks and Ca(2+)-activated K(+) channels by cAMP. Am J Physiol Cell Physiol (2001) 1.16
A potential role for nuclear factor of activated T-cells in receptor tyrosine kinase and G-protein-coupled receptor agonist-induced cell proliferation. Biochem J (2002) 1.12
Transient down-regulation of L-type Ca(2+) channel and dystrophin expression after balloon injury in rat aortic cells. Cardiovasc Res (2001) 1.10
Phosphatidylinositol 3-kinase and calcium-activated transcription pathways are required for VLDL-induced smooth muscle cell proliferation. Circ Res (2003) 1.07
Essential role of calcium in vascular endothelial growth factor A-induced signaling: mechanism of the antiangiogenic effect of carboxyamidotriazole. FASEB J (2002) 1.05
The alternative carboxyl termini of avian cardiac and brain sarcoplasmic reticulum/endoplasmic reticulum Ca(2+)-ATPases are on opposite sides of the membrane. J Biol Chem (1992) 1.02
Regulation of nuclear factor of activated T cells (NFAT) in vascular endothelial cells. J Mol Cell Cardiol (2009) 1.01
Ca2+-ATPases in non-failing and failing heart: evidence for a novel cardiac sarco/endoplasmic reticulum Ca2+-ATPase 2 isoform (SERCA2c). Biochem J (2006) 0.97
Therapeutic potential of a synthetic peptide inhibitor of nuclear factor of activated T cells as antirestenotic agent. Arterioscler Thromb Vasc Biol (2006) 0.90
How many Ca(2)+ATPase isoforms are expressed in a cell type? A growing family of membrane proteins illustrated by studies in platelets. Platelets (2005) 0.89
Mutation of delta-sarcoglycan is associated with Ca(2+) -dependent vascular remodeling in the Syrian hamster. Am J Pathol (2007) 0.84
Lesions in ryanodine channels in smooth muscle cells exposed to oxidized low density lipoprotein. Arterioscler Thromb Vasc Biol (2000) 0.81
Implication of adenylyl cyclase 8 in pathological smooth muscle cell migration occurring in rat and human vascular remodelling. J Pathol (2010) 0.78
Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair. Nat Med (2007) 3.98
Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. Sci Transl Med (2012) 3.53
Functional near-infrared fluorescence imaging for cardiac surgery and targeted gene therapy. Mol Imaging (2002) 3.37
Titin isoform switch in ischemic human heart disease. Circulation (2002) 3.05
Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial. J Card Fail (2009) 2.89
Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1. Circ Res (2005) 2.52
Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure. J Am Coll Cardiol (2008) 2.29
Long-term effects of AAV1/SERCA2a gene transfer in patients with severe heart failure: analysis of recurrent cardiovascular events and mortality. Circ Res (2013) 2.12
In vivo tracking of stem cells for clinical trials in cardiovascular disease. Circulation (2004) 2.11
A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes. J Mol Cell Cardiol (2011) 2.07
Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome. Circ Res (2012) 2.06
Effects of Na(+)/Ca(2+)-exchanger overexpression on excitation-contraction coupling in adult rabbit ventricular myocytes. J Mol Cell Cardiol (2002) 2.00
Functional consequences of caspase activation in cardiac myocytes. Proc Natl Acad Sci U S A (2002) 1.98
Type 1 phosphatase, a negative regulator of cardiac function. Mol Cell Biol (2002) 1.97
Critical role for stromal interaction molecule 1 in cardiac hypertrophy. Circulation (2011) 1.91
SUMO1-dependent modulation of SERCA2a in heart failure. Nature (2011) 1.89
PICOT inhibits cardiac hypertrophy and enhances ventricular function and cardiomyocyte contractility. Circ Res (2006) 1.80
Systems pharmacology of adverse event mitigation by drug combinations. Sci Transl Med (2013) 1.78
Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling. Proc Natl Acad Sci U S A (2004) 1.77
Angiotensin II-induced negative inotropy in rat ventricular myocytes: role of reactive oxygen species and p38 MAPK. Am J Physiol Heart Circ Physiol (2005) 1.73
Targeted sarcoplasmic reticulum Ca2+ ATPase 2a gene delivery to restore electrical stability in the failing heart. Circulation (2012) 1.71
Mechanical and metabolic rescue in a type II diabetes model of cardiomyopathy by targeted gene transfer. Mol Ther (2006) 1.71
Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy. Circulation (2009) 1.71
Mitral regurgitation augments post-myocardial infarction remodeling failure of hypertrophic compensation. J Am Coll Cardiol (2008) 1.70
Stem cell factor gene transfer promotes cardiac repair after myocardial infarction via in situ recruitment and expansion of c-kit+ cells. Circ Res (2012) 1.68
Cardiac sodium channel gene variants and sudden cardiac death in women. Circulation (2007) 1.67
PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signaling. Circ Res (2008) 1.66
cAMP-binding protein Epac induces cardiomyocyte hypertrophy. Circ Res (2005) 1.66
CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury. Cardiovasc Res (2006) 1.64
Increased leakage of sarcoplasmic reticulum Ca2+ contributes to abnormal myocyte Ca2+ handling and shortening in sepsis. Crit Care Med (2005) 1.63
SUMO-1 gene transfer improves cardiac function in a large-animal model of heart failure. Sci Transl Med (2013) 1.59
Cyclosporine attenuates cardiomyocyte hypertrophy induced by RAF1 mutants in Noonan and LEOPARD syndromes. J Mol Cell Cardiol (2011) 1.55
Targeting phospholamban by gene transfer in human heart failure. Circulation (2002) 1.55
Inhibition of PKCα/β with ruboxistaurin antagonizes heart failure in pigs after myocardial infarction injury. Circ Res (2011) 1.55
Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins. J Mol Cell Cardiol (2007) 1.54
Alteration in temporal kinetics of Ca2+ signaling and control of growth and proliferation. Biol Cell (2004) 1.53
Inducible expression of active protein phosphatase-1 inhibitor-1 enhances basal cardiac function and protects against ischemia/reperfusion injury. Circ Res (2009) 1.52
Inhibition of ErbB2 causes mitochondrial dysfunction in cardiomyocytes: implications for herceptin-induced cardiomyopathy. J Am Coll Cardiol (2004) 1.46
Gene therapy for heart failure. Circ Res (2012) 1.46
Fetal cells traffic to injured maternal myocardium and undergo cardiac differentiation. Circ Res (2011) 1.45
Targeted SERCA2a gene expression identifies molecular mechanism and therapeutic target for arrhythmogenic cardiac alternans. Circ Arrhythm Electrophysiol (2009) 1.44
MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors. Circulation (2013) 1.42
Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology. J Mol Cell Cardiol (2009) 1.42
Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle. J Clin Invest (2011) 1.42
AKT signalling in the failing heart. Eur J Heart Fail (2011) 1.41
Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure. Expert Opin Biol Ther (2010) 1.41
SERCA2a gene transfer decreases sarcoplasmic reticulum calcium leak and reduces ventricular arrhythmias in a model of chronic heart failure. Circ Arrhythm Electrophysiol (2011) 1.40
RNA interference targeting STIM1 suppresses vascular smooth muscle cell proliferation and neointima formation in the rat. Mol Ther (2008) 1.36
Acute beta-adrenergic overload produces myocyte damage through calcium leakage from the ryanodine receptor 2 but spares cardiac stem cells. J Biol Chem (2007) 1.36
Role of resistin in cardiac contractility and hypertrophy. J Mol Cell Cardiol (2008) 1.35
A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes. Chem Biol (2011) 1.35
Distinct roles of microRNA-1 and -499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes. PLoS One (2011) 1.34
Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models. Mol Ther (2011) 1.34
Sarco/endoplasmic reticulum Ca2+-ATPase gene transfer reduces vascular smooth muscle cell proliferation and neointima formation in the rat. Circ Res (2005) 1.33
CXCR4 modulates contractility in adult cardiac myocytes. J Mol Cell Cardiol (2006) 1.31
Prevention of ventricular arrhythmias with sarcoplasmic reticulum Ca2+ ATPase pump overexpression in a porcine model of ischemia reperfusion. Circulation (2008) 1.30
Localization and quantification of platelet-rich thrombi in large blood vessels with near-infrared fluorescence imaging. Circulation (2006) 1.28
The opposing effects of CCN2 and CCN5 on the development of cardiac hypertrophy and fibrosis. J Mol Cell Cardiol (2010) 1.27
Novel technique of aortic banding followed by gene transfer during hypertrophy and heart failure. Physiol Genomics (2002) 1.27
Plasticity of surface structures and β(2)-adrenergic receptor localization in failing ventricular cardiomyocytes during recovery from heart failure. Circ Heart Fail (2012) 1.23
The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: a potent target for cardiovascular diseases. Nat Clin Pract Cardiovasc Med (2008) 1.21
Early repair of moderate ischemic mitral regurgitation reverses left ventricular remodeling: a functional and molecular study. Circulation (2007) 1.20
Multidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferation. J Clin Invest (2008) 1.19
The Wnt/beta-catenin pathway is activated during advanced arterial aging in humans. Aging Cell (2010) 1.19
A novel mutant cardiac troponin C disrupts molecular motions critical for calcium binding affinity and cardiomyocyte contractility. Biophys J (2008) 1.18
SERCA2a gene transfer enhances eNOS expression and activity in endothelial cells. Mol Ther (2010) 1.18
Toll-like receptor 2 activation by bacterial peptidoglycan-associated lipoprotein activates cardiomyocyte inflammation and contractile dysfunction. Crit Care Med (2007) 1.16
Ca2+ cycling and new therapeutic approaches for heart failure. Circulation (2010) 1.16
Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium. FASEB J (2013) 1.15
Altered sarcoplasmic reticulum calcium cycling--targets for heart failure therapy. Nat Rev Cardiol (2012) 1.15
Shrink-film configurable multiscale wrinkles for functional alignment of human embryonic stem cells and their cardiac derivatives. Adv Mater (2011) 1.14
Abnormal muscle mechanosignaling triggers cardiomyopathy in mice with Marfan syndrome. J Clin Invest (2014) 1.13
Inhibition of MRP4 prevents and reverses pulmonary hypertension in mice. J Clin Invest (2011) 1.13
Small molecule-mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes. Stem Cells Transl Med (2013) 1.13
Targeting calcium cycling proteins in heart failure through gene transfer. J Physiol (2003) 1.12
Quantitation of CXCR4 expression in myocardial infarction using 99mTc-labeled SDF-1alpha. J Nucl Med (2008) 1.12
Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy. Nat Clin Pract Cardiovasc Med (2008) 1.12