C Abell

Author PubWeight™ 35.58‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Quantitative detection of protein expression in single cells using droplet microfluidics. Chem Commun (Camb) 2007 2.37
2 Crystal structure of aspartate decarboxylase at 2.2 A resolution provides evidence for an ester in protein self-processing. Nat Struct Biol 1998 1.89
3 Isolation and characterisation of a cDNA clone for a chlorophyll synthesis enzyme from Euglena gracilis. The chloroplast enzyme hydroxymethylbilane synthase (porphobilinogen deaminase) is synthesised with a very long transit peptide in Euglena. Eur J Biochem 1989 1.31
4 Purification, N-terminal amino acid sequence and properties of hydroxymethylbilane synthase (porphobilinogen deaminase) from Escherichia coli. Biochem J 1986 1.19
5 Escherichia coli L-aspartate-alpha-decarboxylase: preprotein processing and observation of reaction intermediates by electrospray mass spectrometry. Biochem J 1997 1.17
6 Tandem overproduction and characterisation of the nuclease domain of colicin E9 and its cognate inhibitor protein Im9. Eur J Biochem 1994 1.10
7 Experiences with the shikimate-pathway enzymes as targets for rational drug design. Biochem Soc Trans 2003 1.05
8 The sequence of hemC, hemD and two additional E. coli genes. Nucleic Acids Res 1988 1.03
9 Direct and sensitive detection of a human virus by rupture event scanning. Nat Biotechnol 2001 1.02
10 Evidence from kinetic isotope studies for an enolate intermediate in the mechanism of type II dehydroquinases. Biochem J 1996 0.98
11 Cloning and sequencing of the Escherichia coli panB gene, which encodes ketopantoate hydroxymethyltransferase, and overexpression of the enzyme. J Bacteriol 1993 0.94
12 Binding of vancomycin group antibiotics to D-alanine and D-lactate presenting self-assembled monolayers. Bioorg Med Chem 2000 0.93
13 The final step of pantothenate biosynthesis in higher plants: cloning and characterization of pantothenate synthetase from Lotus japonicus and Oryza sativum (rice). Biochem J 1999 0.93
14 Acute toxoplasmosis complicating leukemia. Diagnosis by bone marrow aspiration. Am J Dis Child 1969 0.92
15 Evidence that pyridoxal phosphate modification of lysine residues (Lys-55 and Lys-59) causes inactivation of hydroxymethylbilane synthase (porphobilinogen deaminase). Biochem J 1989 0.92
16 The crystal structure of E. coli pantothenate synthetase confirms it as a member of the cytidylyltransferase superfamily. Structure 2001 0.91
17 Studies on the mechanism of hydroxymethylbilane synthase concerning the role of arginine residues in substrate binding. Biochem J 1991 0.91
18 Escherichia coli dihydrodipicolinate synthase: characterization of the imine intermediate and the product of bromopyruvate treatment by electrospray mass spectrometry. Biochem J 1995 0.90
19 Mechanistic studies on type I and type II dehydroquinase with (6R)- and (6S)-6-fluoro-3-dehydroquinic acids. Bioorg Med Chem Lett 2000 0.90
20 Escherichia coli chorismate synthase catalyzes the conversion of (6S)-6-fluoro-5-enolpyruvylshikimate-3-phosphate to 6-fluorochorismate. Implications for the enzyme mechanism and the antimicrobial action of (6S)-6-fluoroshikimate. J Biol Chem 1995 0.88
21 Posttranslational modification of Klebsiella pneumoniae flavodoxin by covalent attachment of coenzyme A, shown by 31P NMR and electrospray mass spectrometry, prevents electron transfer from the nifJ protein to nitrogenase. A possible new regulatory mechanism for biological nitrogen fixation. Biochemistry 1992 0.87
22 Crystal structure of Escherichia coli ketopantoate reductase at 1.7 A resolution and insight into the enzyme mechanism. Biochemistry 2001 0.86
23 Identification of Tyr58 as the proton donor in the aspartate-alpha-decarboxylase reaction. Chem Commun (Camb) 2001 0.85
24 Investigation of putative active-site lysine residues in hydroxymethylbilane synthase. Preparation and characterization of mutants in which (a) Lys-55, (b) Lys-59 and (c) both Lys-55 and Lys-59 have been replaced by glutamine. Biochem J 1990 0.83
25 Mechanistic and inhibition studies of chorismate-utilizing enzymes. Biochem Soc Trans 2005 0.82
26 Biophysical tools to monitor enzyme-ligand interactions of enzymes involved in vitamin biosynthesis. Biochem Soc Trans 2005 0.82
27 Studies with substrate and cofactor analogues provide evidence for a radical mechanism in the chorismate synthase reaction. J Biol Chem 2000 0.80
28 Structural insights into the evolution of the pantothenate-biosynthesis pathway. Biochem Soc Trans 2003 0.79
29 Combinatorial synthetic design. Curr Opin Chem Biol 1999 0.78
30 Pantothenate biosynthesis in higher plants. Biochem Soc Trans 2005 0.78
31 Escherichia coli chorismate synthase: a deuterium kinetic-isotope effect under single-turnover and steady-state conditions shows that a flavin intermediate forms before the C-(6proR)-H bond is cleaved. Biochem J 1995 0.78
32 Terpenoid biosynthesis and the stereochemistry of enzyme-catalysed allylic addition-elimination reactions. Philos Trans R Soc Lond B Biol Sci 1991 0.78
33 Chemical force microscopy with active enzymes. Biophys J 2001 0.77
34 Nonlinear analysis of partial dopamine agonist effects on cAMP in C6 glioma cells. J Pharmacol Toxicol Methods 2001 0.76
35 Observation of a secondary tritium isotope effect in the chorismate synthase reaction. Biochemistry 1995 0.76
36 Direct and quantitative detection of bacteriophage by "hearing" surface detachment using a quartz crystal microbalance. Anal Chem 2001 0.76
37 An amino acid sequence motif observed amongst enzymes of the shikimate pathway. Biochem J 1991 0.75
38 Purification, characterization, crystallisation and X-ray analysis of selenomethionine-labelled hydroxymethylbilane synthase from Escherichia coli. Eur J Biochem 1993 0.75
39 Preparation of symmetrical and unsymmetrical DNA-protein conjugates with DNA as a molecular scaffold. Chembiochem 2001 0.75
40 Substrate deactivation of phenylalanine-sensitive 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase by erythrose 4-phosphate. Biochemistry 2001 0.75
41 Diabetic clinics: setting up. Practitioner 1990 0.75
42 Teaching "family": evaluating a multidimensional clerkship curriculum. Fam Med 1996 0.75
43 Novel chemical tagging method for combinatorial synthesis utilizing suzuki chemistry and fourier transform ion cyclotron resonance mass spectrometry. J Comb Chem 2001 0.75
44 Irreversible inhibition of type I dehydroquinase by substrates for type II dehydroquinase. Bioorg Med Chem Lett 2000 0.75